• Title/Summary/Keyword: Optical Tomography

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Implementation of Cost-effective Common Path Spectral Domain Free-hand Scanning OCT System

  • Shoujing Guo;Xuan Liu;Jin U. Kang
    • Current Optics and Photonics
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    • v.7 no.2
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    • pp.176-182
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    • 2023
  • Optical coherence tomography (OCT) is being developed to guide various ophthalmic surgical procedures. However, the high cost of the intraoperative OCT system limits its availability mostly to the largest hospitals and healthcare systems. In this paper, we present a design and evaluation of a low-cost intraoperative common-path free-hand scanning OCT system. The lensed fiber imaging probe is designed and fabricated for intraocular use and the free-hand scanning algorithm that could operate at a low scanning speed was developed. Since the system operates at low frequencies, the cost of the overall system is significantly lower than other commercial intraoperative OCT systems. The assembled system is characterized and shows that it meets the design specifications. The handheld OCT imaging probe is tested on multilayer tape phantom and ex-vivo porcine eyes. The results show that the system could be used as an intraoperative intraocular OCT imaging device.

Common-path Optical Interferometry for Stabilized Dynamic Contrast Imaging: A Feasibility Study

  • Seung-Jin, Lee;Young-Wan, Choi;Woo June, Choi
    • Current Optics and Photonics
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    • v.7 no.1
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    • pp.65-72
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    • 2023
  • The motion of organelles inside a cell is an important intrinsic indicator for assessing cell physiology and tissue viability. Dynamic contrast full-field optical coherence tomography (D-FFOCT) is a promising imaging technology that can visualize intracellular movements using the variance of temporal interference signals caused by biological motions. However, double-path interferometry in D-FFOCT can be highly vulnerable to surrounding noise, which may cause turbulence in the interference signals, contaminating the sample dynamics. Therefore, we propose a method for stabilized D-FFOCT imaging in noisy environments by using common-path interferometry in D-FFOCT. A comparative study shows that D-FFOCT with the proposed method achieves stable dynamic contrast imaging of a scattering phantom in motion that is over tenfold more noise-insensitive compared to the conventional one, and thus this imaging capability can provide cleaner motion contrast images. With the proposed approach, the intracellular dynamics of biological samples are imaged and monitored.

Fabrication of an On System based on an Optical Delay line with Cylindrical PZT (실린더형 압전소자 광지연선을 이용한 광 간섭형 단층촬영(OCT) 시스템 제작)

  • Park, Sung-Jin;Kim, Young-Kwan;Kim, Yong-Pyung
    • Korean Journal of Optics and Photonics
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    • v.17 no.2
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    • pp.159-164
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    • 2006
  • We demonstrate a compact optical coherence tomography(OCT) system based on the optical fiber delay line controlled by a cylindrical piezo-electric transducer(PZT). An 18-m length of single mode fiber is wrapped under constant tension around a PZT. Approximately 134 windings are used. Wraps of the long length of fiber allow the small expansion of the PZT to be magnified to an optical path length delay of 0.78 m. The OCT system shows characteristics for 2-dimensional imaging, exhibiting 96.9dB of signal-to-noise ratio(SNR), $18.6{\pm}0.5\;{\mu}m$ of axial resolution, and $5\;{\mu}m$ of lateral resolution with samples.

Study on application to the field of dentistry using optical coherence tomography (OCT) (치의학 분야에 대한 광간섭 단층영상기기(optical coherence tomography)의 적용 가능성 고찰)

  • Pyo, Se-Wook;Lim, Young-Joon;Lee, Won-Jin;Lee, Jun-Jae
    • The Journal of Korean Academy of Prosthodontics
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    • v.55 no.1
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    • pp.100-110
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    • 2017
  • Purpose: This paper describes the basic principles and the feasibility of the field of dental diagnosis of optical coherence tomography (OCT) used in diverse field of medical diagnosis. Materials and methods: In this review, the research data of OCT were searched from PubMed, medical journal and related papers. Results: Generally, OCT is noninvasive and is possible to secure an excellent spatial resolution and real-time images of biological microstructure. Conclusion: This review discusses not only the basic principles of operation, types, advantages, disadvantages of OCT but also the future applications of OCT technology and their potential in the field of dental diagnosis.

Evaluation of sealant microleakage using Swept-Source Optical Coherence Tomography (치면열구전색치아의 미세누출 평가를 위한 Swept-Source Optical Coherence Tomography의 타당도 평가)

  • Nam, Sang-Mi;Ku, Hye-Min;Lee, Eun-Song;Kim, Baek-Il
    • The Journal of the Korean dental association
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    • v.56 no.12
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    • pp.686-694
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    • 2018
  • Purpose: The aim of this study was to evaluate the validity of swept-source optical coherence tomography (SS-OCT) for detecting sealant microleakage. Materials and Methods: A total of 31 extracted sound human molar, assigned as suitable for sealant application, were chosen and divided into two groups: (1) no microleakage group and (2) microleakage group by applying sealant using the different methods. All specimens were immersed in 1% methylene blue for 24 h and sectioned to confirm the absence or presence of sealant microleakage as a gold standard method. Subsequently, all the sectioned specimens were digitally photographed using a microscope with a magnification of ${\times}50$. Presence of microleakage was evaluated on a 2-point rating scale. The association of histological method with conventional methods (visual and tactile assessment) and SS-OCT was assessed using a chi-squared test. The intra- and inter-examiner reliability was calculated using Cohen's Kappa. Results: The SS-OCT showed a sensitivity of 0.73 and a specificity of 1.00, while visual and tactile assessment showed a sensitivity of 0.67 and a specificity of 0.86. The inter-examiner reliability of SS-OCT was 0.79, whereas that of the visual and tactile assessment was 0.53. Conclusions: SS-OCT can be used to non-invasively detect sealant microleakage and to monitor pit and fissure sealant in the clinics.

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Comparisons of the diagnostic accuracies of optical coherence tomography, micro-computed tomography, and histology in periodontal disease: an ex vivo study

  • Park, Jin-Young;Chung, Jung-Ho;Lee, Jung-Seok;Kim, Hee-Jin;Choi, Seong-Ho;Jung, Ui-Won
    • Journal of Periodontal and Implant Science
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    • v.47 no.1
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    • pp.30-40
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    • 2017
  • Purpose: Optical coherence tomography (OCT) is a noninvasive diagnostic technique that may be useful for both qualitative and quantitative analyses of the periodontium. Micro-computed tomography (micro-CT) is another noninvasive imaging technique capable of providing submicron spatial resolution. The purpose of this study was to present periodontal images obtained using ex vivo dental OCT and to compare OCT images with micro-CT images and histologic sections. Methods: Images of ex vivo canine periodontal structures were obtained using OCT. Biologic depth measurements made using OCT were compared to measurements made on histologic sections prepared from the same sites. Visual comparisons were made among OCT, micro-CT, and histologic sections to evaluate whether anatomical details were accurately revealed by OCT. Results: The periodontal tissue contour, gingival sulcus, and the presence of supragingival and subgingival calculus could be visualized using OCT. OCT was able to depict the surface topography of the dentogingival complex with higher resolution than micro-CT, but the imaging depth was typically limited to 1.2-1.5 mm. Biologic depth measurements made using OCT were a mean of 0.51 mm shallower than the histologic measurements. Conclusions: Dental OCT as used in this study was able to generate high-resolution, cross-sectional images of the superficial portions of periodontal structures. Improvements in imaging depth and the development of an intraoral sensor are likely to make OCT a useful technique for periodontal applications.

2-D OCT image implementation using low coherence SLD (Low coherence 특성의 SLD를 이용한 2차원 OCT 영상 구현)

  • 정태호;박양하;오상기;김용평
    • Proceedings of the Optical Society of Korea Conference
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    • 2003.02a
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    • pp.290-291
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    • 2003
  • Optical Coherence Tomography is a new medical dianostic imaging technology which can perform micron resolution cross-sectional or tomograpic imaging in biological tissue. In this paper, we analyze OCT system. And we have 2-dimensional OCT image implementation using low coherence SLD.

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