• The Journal of Engineering Geology
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• v.21 no.1
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• pp.15-24
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• 2011

To clarify the distribution of joints and fracture zones in the Cheongju granitic mass, we analyzed drill-core and geophysical well-logging data obtained at two boreholes located 30 m from each other. Lithological properties were investigated from the drill-core data and the samples were classified based on the rock mass rating (RMR) and on rock quality designation (RQD). Subsurface discontinuities within soft and hard rocks were examined by geophysical well-logging and cross-hole seismic tomography. The velocity structures constructed from seismic tomography are well correlated with the profile of bedrock depth, previously mapped from a seismic refraction survey. Dynamic elastic moduli, obtained from full waveform sonic and ${\gamma}-{\gamma}$ logging, were interrelated with P-wave velocities to investigate the dynamic properties of the rock mass. Compared with the correlation graph between elastic moduli and velocities for hard rock at borehole BH-1, the correlation points for BH-2 data showed a wide scatter. These scattered points reflect the greater abundance of joints and fractures near borehole BH-2. This interpretation is supported by observations by acoustic televiewer (ATV) and optical televiewer (OTV) image loggings.

• Nuclear Engineering and Technology
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• v.55 no.2
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• pp.681-689
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• 2023

Purpose: Muons are characterized by a strong penetrating ability and can travel through thousands of meters of rock, making them ideal to image large volumes and substances typically impenetrable to, for example, electrons and photons. The feasibility of 3D image reconstruction and material identification based on a cosmic ray muons tomography (MT) system with triangular bar plastic scintillator detectors has been verified in this paper. Our prototype shows potential application value and the authors wish to apply this prototype system to 3D imaging. In addition, an MT experiment with the same detector system is also in progress. Methods: A simulation based on GEANT4 was developed to study cosmic ray muons' physical processes and motion trails. The yield and transportation of optical photons scintillated in each triangular bar of the detector system were reproduced. An image reconstruction algorithm and correction method based on muon scattering, which differs from the conventional PoCA algorithm, has been developed based on simulation data and verified by experimental data. Results: According to the simulation result, the detector system's position resolution is below 1 ~ mm in simulation and 2 mm in the experiment. A relatively legible 3D image of lead bricks in size of 20 cm × 5 cm × 10 cm used our inversion algorithm can be presented below 1× 10⁴ effective events, which takes 16 h of acquisition time experimentally. Conclusion: The proposed method is a potential candidate to monitor the cosmic ray MT accurately. Monte Carlo simulations have been performed to discuss the application of the detector and the simulation results have indicated that the detector can be used in cosmic ray MT. The cosmic ray MT experiment is currently underway. Furthermore, the proposal also has the potential to scan the earth, buildings, and other structures of interest including for instance computerized imaging in an archaeological framework.

• Journal of Korean Society of Environmental Engineers
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• v.31 no.6
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• pp.442-448
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• 2009

To evaluate the combustion mechanism of each droplet cluster downstream of the premixed spray flame, the simultaneous time-series measurements were conducted by using optical measurement system consisting of laser tomography, multi-color integrated Cassegrain receiving optics (MICRO) and phase Doppler anemometer (PDA). Furthermore, the group combustion number of droplet cluster was estimated experimentally, and the combustion mechanism of droplet cluster was examined applying the theoretical analysis. The group combustion number, $G_c$, was experimentally estimated about all droplet cluster verified by planar images, and it was classified into the internal group combustion mode and the external group combustion mode according to the theoretical analysis. It is found that there are cases in which the group combustion number estimated experimentally for droplet cluster agree or disagree with the classification by theoretical analysis. The reason of disagreement is considered due to that the group combustion number was only estimated by the geometrical arrangement of droplets in cluster, and that the actual phenomenon is three-dimensional but the measurement system is two-dimensional.

• Korean Journal of Optics and Photonics
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• v.18 no.5
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• pp.345-350
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• 2007

The characteristics of the supercontinuum generated in photonic crystal fibers were investigated by using the generalized nonlinear $Schr\"{o}dinger$ equation and the split-step Fourier method. Based on the simulated results, we generated the supercontinuum spectrum with the flatness of ${\pm}4dB$ in the wavelength range of 650 to 900 nm by employing a 200-fs pulse of Ti:sapphire laser and a commercial photonic crystal fiber.

• Genomics & Informatics
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• v.5 no.2
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• pp.46-55
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• 2007

The convergence of molecular and genetic disciplines with non-invasive imaging technologies has provided an opportunity for earlier detection of disease processes which begin with molecular and cellular abnormalities. This emerging field, known as molecular imaging, is a relatively new discipline that has been rapidly developed over the past decade. It endeavors to construct a visual representation, characterization, and quantification of biological processes at the molecular and cellular level within living organisms. One of the goals of molecular imaging is to translate our expanding knowledge of molecular biology and genomic sciences into good patient care. The practice of molecular imaging is still largely experimental, and only limited clinical success has been achieved. However, it is anticipated that molecular imaging will move increasingly out of the research laboratory and into the clinic over the next decade. Non-invasive in vivo molecular imaging makes use of nuclear, magnetic resonance, and in vivo optical imaging systems. Recently, an interest in Positron Emission Tomography (PET) has been revived, and along with optical imaging systems PET is assuming new, important roles in molecular genetic imaging studies. Current PET molecular imaging strategies mostly rely on the detection of probe accumulation directly related to the physiology or the level of reporter gene expression. PET imaging of both endogenous and exogenous gene expression can be achieved in animals using reporter constructs and radio-labeled probes. As increasing numbers of genetic markers become available for imaging targets, it is anticipated that a better understanding of genomics will contribute to the advancement of the molecular genetic imaging field. In this report, the principles of non-invasive molecular genetic imaging, its applications and future directions are discussed.

• Journal of Trauma and Injury
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• v.19 no.1
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• pp.89-92
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• 2006

Penetrating facial wounds are uncommon and are usually life threatening because of the possibility of brain damage. There are three possible pathways for penetrating the cranium through the orbit: via the orbital roof, via the superior orbital fissure, or between the optic canal and lateral wall of the orbit. Brain injuries resulting from the penetrating wounds show extensive parenchymal damage, hemorrhage, and brain edema. Transorbital penetrating wounds can lead to diverse lesions of the optical apparatus, including the eye globe, the optical nerve, and the chiasm. Moreover, intracerebral structures may be hurt, and bleeding and infection may occur. Early diagnosis and prompt debridement are the fundamental factors affecting the outcome of a penetrating facial wound. An 87-year-old man was admitted to the emergency department with a grinder impacted into the medial aspect of the right eye. On presentation, the man was fully conscious with a Glasgow Coma Scale score of 15 and complained of a visual disturbance of the right eye. Computed tomography demonstrated a right orbital medial and inferior wall fracture, a frontal bone fracture, and a contusional hemorrhage in frontal lobe of the brain. A craniotomy with hematoma removal and repair of the orbital floor was done. He showed no neurological deficits except right visual loss. This appears to be the first report of a man with a penetrating facial wound caused by a grinder, who presented with a potentially disastrous craniocerebral injury that did not lead to any serious neurological seguelae.

• Journal of the Optical Society of Korea
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• v.20 no.6
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• pp.663-668
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• 2016

In single-photon-emission computed tomography (SPECT) with a pixelated semiconductor detector (PSD), not only pinhole collimators but also parallel-hole collimators are often used in preclinical nuclear-medicine imaging systems. The purpose of this study was to evaluate and compare pinhole and parallel-hole collimators in a PSD. For that purpose, we paired a PID 350 (Ajat Oy Ltd., Finland) CdTe PSD with each of the four collimators most frequently used in preclinical nuclear medicine: (1) a pinhole collimator, and (2) low-energy high-resolution (LEHR), (3) low-energy general-purpose (LEGP), and (4) low-energy high-sensitivity (LEHS) parallel-hole collimators. The sensitivity and spatial resolution of each collimator was evaluated using a point source and a hot-rod phantom. The highest sensitivity was achieved using LEHS, followed by LEGP, LEHR, and pinhole. Also, at a source-to-collimator distance of 2 cm, the spatial resolution was 1.63, 2.05, 2.79, and 3.45 mm using pinhole, LEHR, LEGP, and LEHS, respectively. The reconstructed hot-rod phantom images showed that the pinhole collimator and the LEHR parallel-hole collimator give a fine spatial resolution for preclinical SPECT with PSD. In conclusion, we successfully compared different types of collimators for a preclinical pixelated semiconductor SPECT system.

• Current Optics and Photonics
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• v.5 no.3
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• pp.311-321
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• 2021

Indocyanine green (ICG) is a dye approved for use in clinical diagnostics. ICG remains in the intravascular space following intravenous administration, due to its ability to rapidly bind to the plasma proteins, and its therapeutic potential has been studied in well-vascularized cutaneous tumors. Here we have evaluated the clinical response of a subconjunctival tumor to photothermal therapy (PTT) using an ICG-enhanced near-infrared diode laser and its adverse effects, in a rabbit. 22 male New Zealand white rabbits with subconjunctival tumors were enrolled (control group 6, laser-only group 8, laser-with-ICG group 8). Rabbits in the laser-with-ICG group received ICG (twice, 2 mg/kg each time, intravenously) directly followed by irradiation with a diode laser (λ = 810 nm). Rabbits in the laser-only group were irradiated with the diode laser. ICG angiography, ultrasonography, and pathologic examination were performed to evaluate PTT response at specific time points (0, 2, and 4 weeks after PTT). Two weeks after initial treatment, the eight rabbits treated by laser with ICG showed a 100% response rate. There was no clinical response in both laser-only and control groups. ICG-PTT is a potential and effective palliative therapeutic modality for subconjunctival tumors.

• Journal of Sensor Science and Technology
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• v.27 no.5
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• pp.317-327
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• 2018

Terahertz (THz) time-domain spectroscopy(TDS), imaging techniques, and related systems have become mature technologies, widely used in many universities and research laboratories. However, the development of creative technologies still requires improved THz application systems. A few key points are discussed, including the innovative advances of mode-locking energy-emitting semiconductor lasers and better photoconductive semiconductor quantum structures. To realize a compact, low cost, and high performance THz system, it is essential that THz spectroscopy and imaging technologies are better characterized by semiconductor and nano-devices, both static and time-resolved. We introduce the THz spectroscopy and imaging systems, the OSCAT(Optical Sampling by laser CAvity Tuning) system and the ASOPS(ASynchronous Optical Sampling) system, are constructed by our research team. We report on the THz images obtained from their use.

• Journal of the Korean Institute of Telematics and Electronics D
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• v.35D no.11
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• pp.1-9
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• 1998

In this paper, an incoherent imaging of a high-contrast cylindrical cavity in a lossy medium illuminated by the time-harmonic cylindrical wave is obtained via the backprojections of the intensity patterns of the forward total electric field in the cross-borehole measurement configuration. The phenomenon that the interference fringes in the intensity pattern, which are caused by the superposition of the incident field and the scattered field with different optical paths, are removed in the backprojection process is interpreted numerically. This imaging method is validated by imaging an air circular cylinder in a lossy medium of $\varepsilon$$_{r}$=9 and $\sigma$ = 0.0005, 0.002 S/m, and the conditions for obtaining better images are investigated.d.