• Korean Journal of Pharmacognosy
• /
• v.17 no.4
• /
• pp.263-271
• /
• 1986

In order to investigate experimentally the clinical effects of Taeksa-Tang that was prescribed to cure the severe dizziness, the water extract of Taeksa-Tang was experimented about the effects on the diuretic action, the serum lipid, the isolated ileum and heart, the blood vessel, the blood pressure and respiration. The results of this study were obtained as follows: The diuretic action was significantly shown in rabbits. The level of total cholesterol, triglyceride and phopholipid in serum of rabbits given high cholesterol diet were significantly decreased. The contraction of the isolated ileum of mice induced by acetylcholine chloride and barium chloride was remarkably inhibited. The vasodilating and hypotensive actions were noted in rabbits. Negative inotropic action on the isolated frog heart was recognized.

• The Journal of Internal Korean Medicine
• /
• v.32 no.1
• /
• pp.10-25
• /
• 2011

Objectives : Asthma is considered an inflammation disease characterized by airway hyperresponsiveness and pulmonary eosinophilia. Chungsang boha-tang is a herbal medication which has been frequently used in traditional therapeutic agents for asthma. We aimed to observe the clinical effects of Chungsangboha-tang on blood eosinophil, serum IgE, AST, ALT and pulmonary function in asthmatic outpatients. Methods : The subjects consisted of 66 asthmatic patients who had been treated with Chungsangboha-tang among all the asthmatic patients who visited the 5th Internal Medicine of the Oriental Medicine Hospital of Kyung Hee University from November,2004 to November,2009. We observed blood eosinophil, serum IgE, AST, ALT levels and pulmonary function test results as well as medical records of patients to evaluate the effects. Results : Pulmonary function significantly improved after 8 weeks of treatment, and blood eosinophil and serum IgE level significantly decreased after 8 weeks of treatment. AST, ALT levels changed in normal ranges. Chungsangboha-tang was significantly effective on the male patients who had a smoking history and worse initial lab findings. We also observed a significant improvement of pulmonary function and decrease of eosinophil and serum IgE levels in the patient group who had a single treatment of Chungsangboha-tang without steroid therapy. Conclusions : This study shows that Chungsangboha-tang has effects on the improvement of pulmonary function and decrease of eosinophil and serum IgE levels as well as improvement of symptoms. And, 8 weeks of long-term treatment showed no negative effects such as significant increase of AST, ALT levels.

• The Journal of the Society of Stroke on Korean Medicine
• /
• v.21 no.1
• /
• pp.33-38
• /
• 2020

■ Objectives This case report is reported to show the effect of Ukgansan and Hwangnyeonhaedok-tang on a patient who complaining myoclonic seizure due to psychogenic non epileptic seizure, occurred after traumatic stress event. ■ Methods A female patients with myolconic seizure was treated with Ukgansan and Hwangnyeonhaedok-tang during 5 days. Then we assessed dyskinesia severity by AIMS(Abnormal Involuntary Movement Scale) every two days til discharge. ■ Results Seizure decreased two days after hospitalization, then disappeared third day. There was no recurrence till discharge. When she revisited outpatients clinic, there was no symptom. ■ Conclusion This case showed the effect of Ukgansan and Hwangnyeonhaedok-tang on psychogenic epileptic seizure.

• The Journal of Internal Korean Medicine
• /
• v.42 no.3
• /
• pp.403-411
• /
• 2021

Background: This case report shows the effect of Hyulbuchuko-tang on a patient with a contraindication to anticoagulants who complained about dyspnea caused by pulmonary embolism (PE). Case report: A PE patient with dyspnea was treated with herbal medication, Hyulbuchuko-tang, for 28 days. Evaluations took place by assessing time for oxygen application time per day, follow-up chest CT, and D-dimer test results. Oxygen application time per day decreased, and oxygen therapy ended on the 14th day of Hyulbuchuko-tang treatment. Follow-up chest CT showed resolution of PE. The D-dimer level decreased on the 24th day and decreased more after 1 month later. Conclusion: This clinical case study suggests that Hyulbuchuko-tang might be effective in the resolution of PE and can be an option as a treatment for PE patients with contraindications to anticoagulants.

• Journal of Sasang Constitutional Medicine
• /
• v.29 no.3
• /
• pp.280-287
• /
• 2017

Objectives The purpose of this study is to investigate the effect of Jihwangbaekho-tang on chest discomfort of unknown cause in a 52-year-old male patient diagnosed with Soyangin. Methods Patient had chest discomfort. But, the cause of this symptom was not identified by various cardiac examinations. The patient was treated with Soyangin Jihwangbaekho-tang for 2 weeks on the basis of Sasang Constitutional Medicine and the symptoms were evaluated by GAS(Global Assessment Scale). Results After using Jihwangbaekho-tang, GAS score has been decreased from 7 to 3. Conclusions This case study suggests that chest discomfort, whose cause is unknown, can be treated when using Sasang Constitutional Medicine.

• The Journal of Korean Medicine
• /
• v.35 no.2
• /
• pp.69-78
• /
• 2014

Objectives: This case report was executed to confirm the efficacy and safety of Injincheonggan-tang on two patients with HBeAg-negative chronic hepatitis B. Methods: We reviewed the changes of clinical progress and laboratory records of patients with chronic hepatitis B who did not want to take any antiviral or interferon therapy. One patient has visited the department of internal medicine I of Kyung Hee University Korean Medicine Hospital, from October 2010 and the other, from October 2006. Both of them were prescribed with Injincheonggan-tang and laboratory tests were conducted as well. Results and Conclusions: AST, ALT and HBV DNA which are significant indicators of liver function were controlled in the normal range during the herbal treatment period and subjective clinical symptoms were also improved after taking Injincheonggan-tang.

• Journal of Korean Medicine for Obesity Research
• /
• v.9 no.1
• /
• pp.23-36
• /
• 2009

Objectives The purpose of this study is to research related to Taeeumjowui-Tang(Taiyintiaowei-tang) in oriental medicine. Methods "Taeeumjowui-Tang" was used as a search term. In order to see detail review, we classified all the searched study into type, method, purpose, item of evaluation, composition of herbal medication. Results We found out total twenty six studies. They were fifteen pieces of experimental studies, five clinical case studies, five case reports and one literature review according to type and method. There were fourteen thesis that experiments on efficacy and effect in the purpose of study. Only one thesis showed about stability and toxicity. There were eleven prescription of different composition and dosage. In the item of evaluation, serum biochemical analysis, cell study, body and organ weight, food consumption, body mass index, waist circumference, waist-hip circumference ratio, bioelectrical impedance analysis were used. Conclusion To improve more objective and continuous research in oriental medicine, it is needed unity about prescription and dosage, activation of clinical trial research and variation of research subject.

• The Journal of the Society of Stroke on Korean Medicine
• /
• v.8 no.1
• /
• pp.58-62
• /
• 2007

Objective : Stroke patients tend to take antibiotics due to infection resulting from complication. One of many side effects from using antibiotics is diarrhea, which infact causes anaerobic organism dysfunction resulting Pseudo-Membranous Colitis (P.M.C). To treat P.M.C, antibiotics and antibacterial agents are usually used. But they may cause other side effects, therefore extreme caution must be taken. Methods : We treated an antibiotic induced P.M.C patient who diagnosed by sigmoid scopy with only Yijoong-tang (Lizhong-tang) without antibiotics and observed patients stool aspects. Results and Conclusion : Patiensts symptom was improved after 7days, and we can see the improvement by follow-up sigmoid scopy. This case may give us a possibility of that oriental medical treatments as complementary and alternative medicine to standard antibiotic treatment.

• The Journal of Internal Korean Medicine
• /
• v.28 no.1
• /
• pp.133-148
• /
• 2007

Objectives : The purpose of our study was to investigate the effects of Injinchunggan-tang (Yinchenchinggan-tang) on DMN liver damage caused by applying proteomics. Materials and Methods: Sprague-Dawley rats were used in this experiment; the rats were divided into the normal group (normal saline), the control group (DMN) and the samplegroup (DMN+IJCGT). The DMN was induced 3 days a week for 3 weeks in the control group. The normal saline without DMN was induced by the same method in the normal group. Injinchunggan-tang extract was orally administered twice a day for 3 weeks after DMN was induced in the sample group. The livers of each group were processed and we investigated histology, OxyBlot, 2-dimensional electrophoresis, and western blot of liver of each group. Results : In the histological findings of the liver, the control group showed portal fibrosis with a few septa or without septa. The sample group showed no fibrosis or portal fibrosis without septa. In the OxyBlot finding, Injinchunggan-tang prevented liver damage by oxidation. In the 2-dimensional electrophoresis finding, formiminotransferase cyclodeaminase (FTCD), FYVE-finger containing protein, aldehyde dehydrogenase (ALDH), and ratio of predicted : hypothetical protein LOC68668 isoform 1 were changed. Conclusions : Injinchunggan-tang exerts an inhibitory effect against the fibrosis and oxidation induced by the DMN in the rat liver cell, and some proteins induced by the DMN were changed by Injinchunggan-tang.

• Journal of Sasang Constitutional Medicine
• /
• v.28 no.3
• /
• pp.205-214
• /
• 2016

Objectives This paper was aimed to review the preceding research on the origins, changes and constructive principle of Taeeumjowi-tang.Methods We reviewed Jema Lee's original works including Dongyisusebowon and relevant books to analyze Taeeumjowi-tang-related items. To compensate insufficient evidence of literature, we also refocued physiological and pathological pecularities of Taeeumin and relevant symptomatology.Results and Conclusions 1) The origins of Taeeumjowi-tang should be Mahwang-tang, Saengmaek-san, Seokchangpowonji-san, and Gondam-san. 2) Taeeumjowi-tang went through Saengmaek-san, Sanyakhwawi-jeon, Bopyesaengmaek-tang, Gilgyungsaengmaek-san, and Bopyewon-tang before it was built as the final version. 3) Taeeumjowi-tang consists of a) big blue lilyturf (麥門冬) and Omija (五味子) which are directly of help to exhale and disperse qi-fluid of Lung, b) balloon-flower (桔梗) which helps circulation of qi-fluid from Head to Lung, c) adlay (薏苡仁) and dry nut (乾栗) which are directly of help to raise up qi-fluid of Wiwan, d) ephedra (麻黃) which helps circulation of qi-fluid from Wiwan to skin, e) calamus (石菖蒲) which directly helps the psychological function of Ear, and f) radish seed (蘿葍子) which slightly eliminate the excessive function of Small intestine, treating Wiwanhan symptomatology in Taeeumin.