• Journal of Physiology & Pathology in Korean Medicine
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• v.28 no.2
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• pp.195-199
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• 2014

Although the Herba Cirsii is known to posses beneficial health effects, the anti-diabetic effects and the mechanism of action have not been elucidated. In the present study we have shown that Herba Cirsii Extract (HCE) can stimulate glucose uptake in OP9 adipocytes. Unlike insulin, HCE did not stimulate the Ser473 phosphorylation and activation of Akt. The increasing effects of HCE on glucose uptake were inhibited by PD680509 and compound C pretreatment, which means that the glucose uptake effects by HCE were carried out by extracelluar signal-regulated kinase1/2(ERK1/2) and AMP-activated protein kinase (AMPK) activation. Further studies revealed that HCE stimulated glucose transport occurs through a mechanism involving ERK1/2 activation and AMPK activation.

• Journal of the Korean Institute of Telematics and Electronics D
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• v.34D no.12
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• pp.39-45
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• 1997

This study presents the first experimental data for the impact of hot-carrier degradtion on the performance of CMOS folded-cascode op-amps. A folded-cascode op-amp which has an NMOS input pair has been designed and fabricated using a 0.8.mu.m single-poly, double-metal CMOS process. After high voltage stress, the degradtion of perfomrance parameters such as open-metal CMOS process. After high voltage stress, the degradation of performance parameters such as open-loop voltage gain, unity-gain frequency and phase margin has been analized and physically explaniend in terms of hot carrier degradation.

• International Commerce and Information Review
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• v.9 no.2
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• pp.205-230
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• 2007

In modern manufacturing practice it is sometimes necessary to send products to another country for special processing which cannot be performed inside the territory of the zone and Outward Processing(OP) covers such situation. What's more, process and Rules of Origin(RoO) of OP is implicated in Korea' Free Trade Agreement(Korea-Singapore, Korea-EFTA and Korea-Asean FTA) because of the goods to be producted in Kaesong Industrial Complex. Thus, In this paper analyse a implication of OP's process and RoO focused on the two fold : (1) provide an overview of the objectives, types, effects of Outward Processing described in customs law and FTA provisions of EU and Korea; (2) present a comparative analysis of EU and Korean rules; (3) offer an appropriate proposal to Korea-EU FTA negotiation.

• Journal of Communications and Networks
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• v.11 no.5
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• pp.445-454
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• 2009

Cooperative transmission protocols are always designed to achieve the largest diversity gain and the network capacity simultaneously. The concept of diversity-multiplexing tradeoff (DMT) in multiple input multiple output (MIMO) systems has been extended to this field. However, DMT constrains a better understanding of the asymptotic interplay between transmission rate, outage probability (OP) and signal-to-noise ratio. Another formulation called the throughput-reliability tradeoff (TRT) was then proposed to avoid such a limitation. By this new rule, Azarian and Gamal well elucidated the asymptotic trends exhibited by the OP curves in block-fading MIMO channels. Meanwhile they doubted whether the new rule can be used in more general channels and protocols. In this paper, we will prove that it does hold true in decode-and-forward cooperative protocols. We deduce the theoretic OP curves predicted by TRT and demonstrate by simulations that the OP curves will asymptotically overlap with the theoretic curves predicted by TRT.

• Annals of Clinical Neurophysiology
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• v.20 no.1
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• pp.41-43
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• 2018

ntermediate syndrome (IMS) typically occurs at 24-96 hours following organophosphate (OP) poisoning, after an acute cholinergic crisis, but before OP-induced delayed polyneuropathy. It is characterized by proximal muscle weakness and respiratory insufficiency, which is a major contributing factor of OP-related morbidity and mortality. We report an atypical IMS case showing rapid-onset ascending paralysis and respiratory disturbance with an acute cholinergic crisis occurring 4-5 days after skin exposure to OP.

• Proceedings of the KIEE Conference
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• 1993.07a
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• pp.479-482
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• 1993

A fully balanced differential amplifier can achieve high-gain wide-bandwidth characteristics. And also, Offset PSRR, CMRR and Noise performance of that are excellent, but these merits can be achieved only when the architecture holds fully balanced. Commonly, the fully balanced differential amplifier has a common mode feedback(CMFB) circuit in order to maintain the balance. This paper presents improved characteristics of the CMFB circuit and designs the wide-bandwidth CMOS Op-amp. The unity gain bandwidth of this Op-amp is 50MHz with the load capacitor 2pF, and the value of phase margin is $85^{\circ}$.

• Proceedings of the Korean Society of Toxicology Conference
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• 2002.11b
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• pp.163-163
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• 2002

4-tert-octylphenol (OP) is surfactant additive widely used in the manufacture of a variety of detergents and plastic products, a U.S. Environmental Protection Agency (EP A) classified endocrine disruptor. The purpose of this study was developed the analytical method of OP and determined toxicokinetics parameters after i. v. and oral administration in SD rats plasma concentration of OP using HPLC.(omitted)

• Proceedings of the Korea Information Processing Society Conference
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• 2013.11a
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• pp.287-289
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• 2013

Fast Handover for Proxy Mobile IPv6 (FPMIPv6), a protocol described in RFC 5949, is used to reduce handover latency and minimize packet loss problem occuring in the Proxy Mobile IPv6 (PMIPv6) protocol. However, during the study of implementing FPMIPv6, we found the Out-of-Order Packet (OoOP) problem that occurs in the experiment of FPMIPv6. Since the OoOP is an issue that affects significantly to QoS of the network, in this paper, we analyze the OoOP problem by using network model. The analysis conducts the cause of occurring OoOP problem due to there exist two paths for data transmitted from Correspondent Node (CN) to MN in FPMIPv6.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.45 no.4
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• pp.227-231
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• 2000

Small seed size is one of the major traits of soybean cultivars for sprouts with regard to high sprout yield. This study was conducted to identify quantitative trait loci (QTL) for seed size and weight in a set of F 6 seeds of 89 lines derived from a cross between 'Pureunkong', a soybean cultivar developed for sprouts and 'Jinpumkong 2', a soybean cultivar with no beany taste in seed due to the lack of lipoxygenases. The genetic map of 25 linkage groups with a total of 98 markers including RFLP, RAPD, SSR and classical markers was constructed from this F/sbu 5/-derived population and was used for QTL analysis. 'Pureunkong' was significantly smaller (P＜0.01) than 'Jinpumkong 2' in seed size and seed weight. Genetic variation was detected and transgressive segregation was common in the population for these traits. Seven DNA markers including opT14-1600 in LG A2, opF02-400 in LG B2, Satt100, opC09-700, opG04-730 and opQll-650 in LG C2, and opY07-1100 ＆ 1000 in LG(unknown) were significantly associated and accounted for 4.7 to 10.9% and 5.1 to 10.1 % of the phenotypic variation in seed size and seed weight, respectively. 'Pureunkong' alleles increased seed size and seed weight at the all four significant marker loci on the LG C2. These marker loci in LG C2 were closely linked and were presumed to be a single QTL. Overall, at least three independent QTLs from 3 linkage groups (A2, B2, and C2) were putatively involved in the control of seed size and seed weight.

• Korean Journal of Environmental Biology
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• v.22 no.4
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• pp.550-558
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• 2004

The effects of postnatal exposure to octylphenol(OP) on the expressions of the steroidogenic enzymes and testosterone production were evaluated. Postnatal male mice (15-day-old) were injected with 2 or 20mg $kg^{-l}$ body weight (BW) of OP for 5 days and sacrificed on postnatal day 21. Testosterone concentration was measured by radioimmunoassay and the expressions of the testicular genes were determined by RT-PCR analyses. Significant reductions in the mean body and testis weight were observed in the OP treated animals. No marked alteration in the histological structure of the testis were observed, however, slight reduction in the seminiferous tubule diameter and the number of Leydig cells and several pyknotic cells could be identified in the 20 mg $kg^{-l}$ BW of the OP treated animals. Serum testosterone concentration was dramatically reduced and the mRNA expressions of the steroidogenic acute regulatory protein (StAR), cholesterol side-chain cleavage enzyme (P450scc) and $17\beta$-hydroxylase/Cl7-20 lyase $(P450_{17\alpha})$ were decreased. No significant changes of the gene expressions of the steroidogenic factor-l (SF-I) and estrogen and androgen receptor after the OP treatment showed that the decreased expressions of the steroidogenic enzymes in the present study did not correlate with these genes. Altogether, the present study demonstrates that postnatal treatment of OP inhibits steroidogenesis by decreasing the transcriptional expressions of the StAR and steroidogenic enzymes. The alteration in steroidogenesis may adversely affect the normal development of the testis and sper- matogenesis.