Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)

Korean Society of Toxicology & Korea Environmental Mutagen Society (한국독성학회)
권호 표지

DEVELOPMENT OF CONVENIENT ANALYTICAL METHOD OF 4-TERT-OCTYLPHENOL

  • Cho, Jae-Min (Department of Pharmacology, National Institute of Toxicological Research) ;
  • Ahn, Mee-Ryung (Department of Pharmacology, National Institute of Toxicological Researc) ;
  • Kwak, Son-Hyok (Department of Pharmacology, National Institute of Toxicological Research) ;
  • Kang, Mi-Kyung (Department of Pharmacology, National Institute of Toxicological Research) ;
  • An, Eun-Ju (Department of Pharmacology, National Institute of Toxicological Research) ;
  • Kim, Jung-Mi (Department of Pharmacology, National Institute of Toxicological Research) ;
  • Park, Sun-Ok (Department of Pharmacology, National Institute of Toxicological Research) ;
  • Park, Hong-Seok (Department of Pharmacology, National Institute of Toxicological Research) ;
  • Chung, Hye-Joo (Department of Pharmacology, National Institute of Toxicological Research)
  • Published : 2002.11.01
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Abstract

4-tert-octylphenol (OP) is surfactant additive widely used in the manufacture of a variety of detergents and plastic products, a U.S. Environmental Protection Agency (EP A) classified endocrine disruptor. The purpose of this study was developed the analytical method of OP and determined toxicokinetics parameters after i. v. and oral administration in SD rats plasma concentration of OP using HPLC.(omitted)

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