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Intermediate syndrome after dermal exposure to organophosphate insecticide

  • Lee, Su Bin (Department of Neurology, Myongji Hospital, Seonam University College of Medicine) ;
  • Ryu, Seung Ho (Department of Neurology, Myongji Hospital, Seonam University College of Medicine) ;
  • Park, Doo Yong (Department of Neurology, Myongji Hospital, Seonam University College of Medicine) ;
  • Park, Jong-Ho (Department of Neurology, Myongji Hospital, Seonam University College of Medicine) ;
  • Kim, Jee Young (Department of Neurology, Myongji Hospital, Seonam University College of Medicine)
  • Received : 2017.06.13
  • Accepted : 2017.12.07
  • Published : 2018.01.31

Abstract

ntermediate syndrome (IMS) typically occurs at 24-96 hours following organophosphate (OP) poisoning, after an acute cholinergic crisis, but before OP-induced delayed polyneuropathy. It is characterized by proximal muscle weakness and respiratory insufficiency, which is a major contributing factor of OP-related morbidity and mortality. We report an atypical IMS case showing rapid-onset ascending paralysis and respiratory disturbance with an acute cholinergic crisis occurring 4-5 days after skin exposure to OP.

Keywords

References

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