• Title/Summary/Keyword: OK-5

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The effect of Picibanil sclerotherapy for benign neck cysts (양성 경부 낭종에서의 Picibanil(OK-432)을 이용한 경화치료 효과)

  • Hong, Ji-Won;Boo, Sung-Hyun;Park, Jae-Hong;Kim, Myung-Gu
    • Korean Journal of Bronchoesophagology
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    • v.14 no.2
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    • pp.31-37
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    • 2008
  • Background and Objectives: In most cases of benign neck cysts, surgical excision has been considered as treatment of choice. However, sometimes complete excision is very difficult, and recurrences has been occured due to insufficient surgery frequently. In this point of view, non-surgical treatment has been attempted with sclerosing agents such as picibanil(OK-432). In this study, we evaluated the efficacy of picibanil sclerotherapy for benign neck cysts. Materials and methods: We retrospectively reviewed 53 patients(27 males, 26 females) who had undergone sclerotherapy with picibanil for benign neck cysts such as ranula, lymphangioma, thyroglossal duct cyst and branchial cyst. Information was gathered with respected to age, sex, number of injections, side effect and outcome of treatment. All patients were treated with intralesional aspiration of cystic contents and injection of picibanil, and followed on neck ultrasonography or neck CT. Results: 53 patients received sonoguided sclerotherapy using picibanil(OK-432). 31 patients(41.3%) showed total shrinkage, near total shrinkage(more than 90% of volume) in 7 patients(9.3%), marked shrinkage(more than 70%) in 5 patients(6.6%) and partial shrinkage(less than 70%) in 17 patients. 15 patients(20%) reaveled no response and 8 patients showed recurrences with repeated sclerotherapy. The side effects of therapy were observed by symptoms such as fever, localized pain and odynophagia. However, these complications disappeared after several days in all cases. Conclusions: We recognized that picibanil(OK-432) sclerotherapy for benign neck cyst is a safe and effective procedures as a primary treatment before considering surgery.

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Transepithelial Transport of Organic Cation and Its Inhibition by Sulfhydryl and Carboxyl Reagents in Opossum Kidney Cell Monolayer

  • Woo, Jae-Suk;Oh, Se-Ok;Jung, Jin-Sup;Kim, Yong-Keun;Lee, Sang-Ho
    • The Korean Journal of Physiology
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    • v.30 no.1
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    • pp.53-62
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    • 1996
  • Transepithelial transport of tetraethylammonium (TEA) was studied in monolayers of opossum kidney cells cultured on permeable membrane filters. $[^{14}C]-TEA$ was transported across the OK cell monolayer from basolateral to apical side by a saturable process which can be stimulated by acidification of the apical medium. The apparent Michaelis-Menten constant $(K_{m})$ and the maximum velocity$(V_{max})$ for the transport were $41\;{\mu}M$ and 147 pmole/ mg protein/ min, respectively. The transport was significantly inhibited by unlabelled TEA, amiloride, cimetidine, choline, and mepiperphenidol added to the basolateral side at 1 mM and was slightly inhibited by 5 mM $N_{1}-methylnicotinamide\;(NMN).$ Unlabelled TEA added to the apical side stimulated the $basolateral-to-apical\;{^{14}C}-TEA$ transport, suggesting that the TEA self-exchange mechanism was involved at the apical membrane. Sulfhydryl reagents such as ${\rho}-chloromercuribenzoic\;acid\;(PCMB)\;and \;{\rho}-chloro-mercuribenzene\;sulfonate \;(PCMBS)$ and carboxyl reagents such as N,N'-dicyclohexylcarbodiimidem (DCCD) and N-ethoxy-carbonyl-2-ethoxy-1,2-dihydro-quinoline(EEDQ) inhibited the TEA transport at both the basolateral and apical membranes of the OK cell monolayer. These results suggest that OK cell monolayers possess a vectorial transport system for organic cations which is similar to that for organic cation secretion in the renal proximal tubule.

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A Study of the Microstructure and Provenance Area of Bronze Spoons Excavated from the Ok-dong Site in Andong (안동 옥동유적 출토 청동시(靑銅匙)의 미세조직 및 산지연구)

  • Chung, Kwang-Yong;Lee, Joo-Hyun
    • Journal of Conservation Science
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    • v.25 no.4
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    • pp.411-420
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    • 2009
  • A series of scientific analyses, including ICP-AES, microstructure, and TIMS, were carried out on 5 bronze spoons among 14 bronze artifacts excavated from the Ok-dong site in Andong, North Gyeongsang Province. The results of analysis showed that the bronze spoons were formed from an alloy of no more than 75% Cu and 21~23% Sn, placing it in the category of brassware, with trace elements such as Pb, Fe, and Zn. In particular, plumbum Pb contents of which traces of 0.04% were found, appears to have been added as an impurity during smelting. The microstructure of the bronze spoons suggests that the casting process involved using a spoon-shaped hollow mold, followed by an ropid-cooling process after the shape was perfected at approximately $586^{\circ}C$. After comparison of data measured from thermal ionization mass spectrometry (TIMS) of galena from Korea, China, and Japan, it appears that the raw materials for the bronze spoons included galena (lead sulfide) produced from the southern part of China.

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A Study on Selection and Measures of the Apprehensive Areas of Soil Loss in the So-ok Stream Watershed (소옥천유역 토양유실 우심지역 선정 및 대책에 관한 연구)

  • Jeong, Dong-Hwan;Kim, Haejung;Lee, Young Joon;Hong, Sunhwa;Yoon, Johee;Choi, Heelak;Cho, Hong-Lae
    • Journal of Environmental Impact Assessment
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    • v.21 no.5
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    • pp.617-629
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    • 2012
  • This study aims to find out critical areas of a soil loss and propose feasible measures to reduce the water quality deterioration by a soil lose. As a study area, the So-ok stream catchment locating at the upper area of Daecheong Reservoir is selected and intensive field observation was carried out. RUSLE model is applied to assess the impact of the pollution migration by a soil ross from the critical areas during storms on the water quality of Chusori embayment. As results, total amount of the soil ross assessed against to the critical area on which major type of land use is a orchard for fruits is 54.3 ton/ha/yr and that of an abandoned mine site is about 200 ton/ha/year. In particular as effective measures, a plantation of an appropriate species of fruit trees and an application of ecologic restoration schemes are proposed against to the orchard and the abandoned mine site, respectively.

Marine Pollution of the East China Sea by Floating Marine Debris(II) - Densities and Composition of each Item - (부유성 해양 폐기물에 의한 동지나해의 해양 오염(II) - 종류별 밀도와 조성을 중심으로 -)

  • Kim, Jong-Hwa
    • Journal of Fisheries and Marine Sciences Education
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    • v.23 no.4
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    • pp.772-778
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    • 2011
  • In order to estimate the densities and composition of floating marine debris (FMD), a sighting survey was conducted from July 1st to July 14th, 2009 in the East China Sea (ECS) using a training vessel "Kaya (1,737 ton)" of Pukyong National University. The sampled zones are divided into 5 transects by observation day during the survey days and the densities and composition in each transect were calculated using the numbers of item per $km^2$. The results of distribution of FMD are as follows: 1. During the surveys, a large variety of FMD was discovered and highest densities were found in the Central East(CE) of the East China Sea(ECS) (48.2 items/$km^2$), whereas densities in the less populated transects in Okinawa(OK1, OK2) were comparatively low(3.5 ~ 4.9 items//$km^2$). 2. Among the classified 6 items, styrofoams(Styro) were most abundant and ubiquitous(10.3 items/$km^2$, 53% of the total number), except OK2 area. Next abundant item was vinyl and plastics called V & P(4.9 items/$km^2$, 25%). Above 2 items of the major proportion of FMD accounted for 78% of the total number of FMD observed through this study. 3. The percentages of manufactured plastics(Styro and V & P) found in the Seas near Korean Peninsula were varied from 87.2% to 69.8%. It was recognized that polluted level is middle value among them.

국제화시대 국제화전략 다룬 책 쏟아진다

  • Jeong, Hye-Ok
    • The Korean Publising Journal, Monthly
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    • s.144
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    • pp.4-5
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    • 1994
  • "국제화해야 21세기에 살아남을 수 있다"는 기업들의 절박한 모토는 국가도 개인도 예외가 아니다. 최근 서점가에 쏟아지고 있는 국제화.개방화에 대비하는 책들은 이러한 문명사적 대전환기를 맞아 작게는 '나', 크게는 기업, 국가가 '어떻게' '구체적'으로 '사고의 전환'을 이루어야 하는지가 조목조목 지적돼 있다.

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