• Title/Summary/Keyword: OAL

Search Result 15, Processing Time 0.026 seconds

Determination of optimal accelerometer locations using modal sensitivity for identifying a structure

  • Kwon, Soon-Jung;Woo, Sungkwon;Shin, Soobong
    • Smart Structures and Systems
    • /
    • v.4 no.5
    • /
    • pp.629-640
    • /
    • 2008
  • A new algorithm is proposed to determine optimal accelerometer locations (OAL) when a structure is identified by frequency domain system identification (SI) method. As a result, a guideline is presented for selecting OAL which can reflect modal response of a structure properly. The guideline is to provide a minimum number of necessary accelerometers with the variation in the number of measurable target modes. To determine OAL for SI applications effectively, the modal sensitivity effective independence distribution vector (MS-EIDV) is developed with the likelihood function of measurements. By maximizing the likelihood of the occurrence of the measurements relative to the predictions, Fisher Information Matrix (FIM) is derived as a function of mode shape sensitivity. This paper also proposes a statistical approach in determining the structural parameters with a presumed parameter error which reflects the epistemic paradox between the determination of OAL and the application of a SI scheme. Numerical simulations have been carried out to examine the proposed OAL algorithm. A two-span multi-girder bridge and a two-span truss bridge were used for the simulation studies. To overcome a rank deficiency frequently occurred in inverting a FIM, the singular value decomposition scheme has been applied.

Effects of Black rice (Oryza sativa L.) Aleurone layer on Cyclophosphamide-induced Immunosuppression in Mice (Cyclophosphamide에 의해 유도된 면역 저하 마우스에서 흑미 (Oryza sativa L.) 호분층의 면역 활성 효과)

  • Lee, Eun Byeol;Choi, Ji-Hye;Kim, Si Hyun;Jang, Hwan Hee;Lee, Sung Hyen
    • Korean Journal of Pharmacognosy
    • /
    • v.52 no.3
    • /
    • pp.170-176
    • /
    • 2021
  • Anthocyanins are considered as one of the major functional components including cyanidin-3-glucoside and peonidin-3-glucoside anthocyanins of black rice (Oryza sativa L., BR) aleurone layer (OAL) extract. The immunomodulatory biological effects of OAL has rarely been evaluated. This study has extensively studied the immunomodulatory effects of BR in immunosuppressed mice by CPA. The immunostimulatory effects of BR extract in in vivo at 150 (OAL-1) and 300 mg/kg body weight (OAL-2) for OAL groups were measured and compared to the normal group (CON) ingested with distilled water only or other groups. After the 14 days of oral administration, immune related organ weights, serum immunoglobulin (Ig) A and IgG, and cytokines (IL-12, TNF-α) levels, splenocytes proliferation rate, and NK cell activity were evaluated as immune related biomarkers. The serum IgA and IgG values in the OAL-treated groups increased to the level of the CON. OAL significantly and effectively controlled the IL-12 and TNF-α levels and NK activity compared to the negative control (NC) group. The results suggest that BR aleurone layer with immunomodulatory activities has a great potential as a functional food by itself or as a supplement.

Homology Modeling and Characterization of Oligoalginate Lyase from the Alginolytic Marine Bacterium Sphingomonas sp. Strain MJ-3 (알긴산을 분해하는 해양미생물인 Sphingomonas sp. MJ-3 균주의 올리고알긴산 분해효소의 상동성 모델링 및 특성연구)

  • Kim, Hee Sook
    • Journal of Life Science
    • /
    • v.25 no.2
    • /
    • pp.121-129
    • /
    • 2015
  • Alginates are found in marine brown seaweeds and in extracellular biofilms secreted by some bacteria. Previously, we reported an oligoalginate lyase from Sphingomonas sp. MJ-3 (MJ3-Oal) that had an exolytic activity and protein sequence homology with endolytic polymannuronate (polyM) lyase in the N-terminal region. In this study, the MJ3-Oal was tested for both exolytic and endolytic activity by homology modeling using the crystal structure of Alg17c from Saccharophagus degradans 2-40T. The tyrosine residue at the $426^{th}$ position, which possibly formed a hydrogen bond with the substrate, was mutated to phenylalanine. The FPLC profiles showed that MJ3-Oal degraded alginate quickly to monomers as a final product through the oligmers, whereas the Tyr426Phe mutant showed only exolytic alginate lyase activity. $^1H$-NMR spectra also showed that MJ3-Oal degraded the endoglycosidic bond of polyM and polyMG (polymannuronate-guluronate) blocks. These results indicate that oligoalginate lyase from Sphingomonas sp. MJ-3 probably catalyzes the degradation of both exo- and endo-glycosidic bonds of alginate.

Determination of Optimal Accelerometer Locations using Mode-Shape Sensitivity (진동형상 민감도에 의한 가속도계 최적위치 결정)

  • Kwon, Soon-Jung;Shin, Soo-Bong
    • Journal of the Earthquake Engineering Society of Korea
    • /
    • v.10 no.6 s.52
    • /
    • pp.29-36
    • /
    • 2006
  • This paper proposes a new algorithm of MS-EIDV (modal sensitivity-effective independence distribution vector) for determining optimal accelerometer locations (OAL) by using the Fisher Information Matrix (FIM) derived from mode-shape sensitivities. Also, the paper provides a reasonable guideline for selecting OAL which can reflect dynamic responses of a structure effectively. Since OAL should be determined with known values of structural parameters but since the parameters can be estimated by applying an inverse method such as SI (system identification) using measured response, the paper proposes a statistical method to overcome the paradox by considering the error bound of the structural parameters. To examine the proposed methods, a frequency-domain SI method has been applied. By using the identified results, the minimum necessary number of accelerometers could be selected depending on the number of target measurable modes. Through simulation studies, the results by applying EIDV method directly using the information of mode shapes were compared with those by applying the proposed MS-EIDV.

Research Trends in Digital Archiving and the OAIS Reference Model (디지럴 아카이빙 최근 연구동향 및 OAIS 참조모형에 관한 연구)

  • Kim, Hee-Jung
    • Journal of Korean Society of Archives and Records Management
    • /
    • v.3 no.1
    • /
    • pp.23-41
    • /
    • 2003
  • This paper reviewed research trends in Digital Archiving and the OAIS Reference Model. Well renowned International Projects are also reviewed. InterPares, NEDLIB, CEDARS, CAMiLEON, PRISM are included. Several key functions of the OAIS Reference Model are presented and further research direction of digital preservation in Korea is also suggested.

A Study on The Relational Database Adoption (관계형 데이타 베이스 채택에 관한 연구)

  • 김윤기;이재범;양경훈
    • Proceedings of the Korean Operations and Management Science Society Conference
    • /
    • 1996.10a
    • /
    • pp.78-88
    • /
    • 1996
  • It is important to understand the process of IT diffusion between organizations for meeting effectively IT progress and its changes. The previous studies provide, the process of IT diffusion between organizational members, organizational factors facilitating the assimilation of IT within the organization, and the organizational members' usage of communication channels in the IT adoption process. But they failed to provide comprehensively the diffusion process of IT between organizations. Therefore, an empirical research through a field survey has been performed to examine the diffusion process of RDB with 64 companies to overcome the limits of the previous studies. The purpose of this study is (1) to empirically examine the interaction of companies(prior adopters and potential adopters), (2) to look into the differences of the factors of organizational structure and the periods of RDB adoption process between OAE(Organizations Adopting Earlier) and OAL(Organizations Adopting Later), and the importance of communication channels used in IT planning stage and adoption stage, (3) to inquire into the difference of RDB performance between OAE and OAL. The results of this study indicate that there is no interaction between the prior adopters and the potential adopters. Also, there are great significant differences with regards to variables of CEO's age, CEO's concern on IT, formalization, centralization compensation systems, CIO's attitudes on changes, RDB adoption periods, performance of RDB. In addition, interpersonal channels have been much more used than mass communication channels in both IT planning stage and adoption stage. This study provides good guidelines to the companies and the vendors in shaping the strategies of IT adoption and IT diffusion respectively.

  • PDF

A Design and Implementation of Data Provider for Developing Features Supporting OAl in MIRAGE (MIRAGE의 OAI지원 기능을 위한 Data Provider 설계 와 구현)

  • 지용인;이종필;이현숙;이만호
    • Proceedings of the Korean Information Science Society Conference
    • /
    • 2002.04b
    • /
    • pp.169-171
    • /
    • 2002
  • MIRAGE는 XML을 기반으로 하는 가상문서라는 개념을 도입하여 인터넷 상의 정보 공유를 가능하게 하여 새로운 지식을 생성할 수 있도록 한 디지털도서관 시스템이다. OAI는 컨텐츠에 대한 메타데이터를 이용해서 디지털도서관 안에 있는 정보를 상호이용하기 위한 프로토콜이다. 본 논문에서는 MIRAGE에 OAI 지원 기능을 첨가하여 MIRAGE 시스템에 의해 만들어진 가상문서에 대한 메타데이터를 제공하는 data provider를 구현하여 다른 디지털도서관과 더불어 정보를 상호이용할 수 있도록 하였다. 또한 원문에 대한 접근을 원하는 사용자를 위해서 메타데이터의 원문에 직접 접근할 수 있도록 하였다.

  • PDF

Synaptic Facilitation of Naive and Depressed Synapses in Aplysia

  • Chang, Deok-Jin;Kaang, Bong-Kiun
    • Proceedings of the Korean Biophysical Society Conference
    • /
    • 2001.06a
    • /
    • pp.23-23
    • /
    • 2001
  • To evaluate the contribution of cAMP/PKA signal pathway in short-term facilitation, we overexpressed Ap oal receptor in sensory neurons that do not normally express this receptor. We have previously shown that activation of this receptor in sensory cells, by a brief treatment with octopamine (OA), produced short-term facilitation such as membrane depolarization, increase in membrane excitability, spike broadening, and enhanced neurotransmitter release in non-depressed synapse.(omitted)

  • PDF

Research on the optimization of off-axis illumination condition and sub-resolution pattern size for the $0.1{\mu}m$ rule dense pattern formation ($0.1{\mu}m$급 dense 패턴 형성을 위한 사입사 조명 조건과 OPC 보조 패턴 크기의 최적 조건에 관한 연구)

  • 박정보;이재봉;이성묵
    • Korean Journal of Optics and Photonics
    • /
    • v.12 no.3
    • /
    • pp.190-199
    • /
    • 2001
  • In this paper, we have researched the depth of focus (DOF) and cutoff intensity of the $0.1{\mu}m$rule dense line'||'&'||'space pattern according to the various off-axis illumination (OAl) conditions in the optical system of 0.65 NA using ArF excimer laser (193 nm). We have also studied the variation of the DOF and cutoff intensity according to the sub-resolution pattern (hammer head type) size for optical proximity correction (OPC) applied to the capacitor pattern and the various OAl conditions in the same optical system. As a result, it is revealed that the cross type quadrupole or annular illumination is preferred to the conventional X type quadrupole for printing the $0.1{\mu}m$ rule dense pattern. Also, we can investigate the optimal illumination condition and the size of ope sub-resolution pattern to keep a consistent DGF and cutoff intensity trends.

  • PDF

Development of Embedded System Based on Windows CE 5.0 (S3C2410A와 Windows CE 5.0 기반의 임베디드시스템 개발에 관한 연구)

  • Kim, Do-Kyu
    • The Journal of Information Technology
    • /
    • v.8 no.4
    • /
    • pp.91-102
    • /
    • 2005
  • In this paper, development of embedded system based on Windows CE 5.0 which released recently is studied. Embedded softwares for the target board using S3C2410A SOC based on ARM920T core are composed of (1) BSP(Board Support Package) contains an OAL(OEM Adaptation Layer) which includes a boot loader for initializing and customizing target hardware, device drivers, and a corresponding set of configuration files (2) Windows CE 5.0 kernel (3) SDK and MP3 test application. Particularly, PB(Platform Builder) provides the efficient functions to build, test and debug the BSP and CE kernel. It is looked forward to being widely spread that Windows CE 5.0 will be utilized at smart devices such as PMP, CNS and DMB phone which inevitably require a display device.

  • PDF