• Fisheries and Aquatic Sciences
• /
• v.26 no.1
• /
• pp.35-47
• /
• 2023

Myelophycus caespitosus, a brown alga belonging to genus Myelophycus, has been traditionally used as a food and medicinal resource in Northeastern Asia. However, few studies have been conducted on its pharmacological activity. In this study, we evaluated whether methanol extract of M. caespitosus (MEMC) could protect against oxidative damage caused by hydrogen peroxide (H₂O₂) in C2C12 murine myoblasts. Our results revealed that MEMC could suppress H₂O₂-induced growth inhibition and DNA damage while blocking the production of reactive oxygen species. In H₂O₂-treated cells, cell cycle progression was halted at the G2/M phase, accompanied by changes in expression of key cell cycle regulators. However, these effects were attenuated by MEMC. In addition, we found that MEMC protected cells from induction of apoptosis associated with mitochondrial impairment caused by H₂O₂ treatment. Furthermore, MEMC enhanced the phosphorylation of nuclear factor-erythroid-2 related factor 2 (Nrf2) and expression and activity of heme oxygenase-1 (HO-1) in H₂O₂-treaetd C2C12 myoblasts. However, such anti-apoptotic and cytoprotective effects of MEMC were greatly abolished by HO-1 inhibitor, suggesting that MEMC could increase Nrf2-mediated activity of HO-1 to protect C2C12 myoblasts from oxidative stress.

• Journal of Industrial Convergence
• /
• v.21 no.11
• /
• pp.67-74
• /
• 2023

This study is a literature review analyzing the characteristics of biophilic design in health and welfare facilities for the elderly, children, and adolescents. Studies on biophilic design in such facilities were selected from two Korean databases. Eight studies were analyzed based on biophilic design elements, and the characteristics of biophilic design were compared between facilities for the elderly and those for children/adolescents. Elderly facilities exhibited more patterns of 'direct experience of nature' than their counterparts, while children/adolescents' facilities displayed more patterns of 'space and place experience' compared to facilities for the elderly. The pattern of 'indirect experience of nature' was similar for both the elderly and children/adolescents. We suggest utilizing more 'direct experience of nature' patterns, such as natural light and water, to reduce stress in vulnerable children and younger individuals. Additionally, incorporating more 'experience of space and place' patterns may help reduce stress and enhance the cognition of older individuals.

• Journal of Preventive Medicine and Public Health
• /
• v.57 no.1
• /
• pp.8-17
• /
• 2024

Objectives: The effectiveness and efficiency of pre-exposure prophylaxis (PrEP) in reducing the transmission of human immunodeficiency virus (HIV) among men who have sex with men (MSM) relies on how widely it is adopted and adhered to, particularly among high-risk groups of MSM. The meta-analysis aimed to collect and analyze existing evidence on various factors related to PrEP adherence in MSM, including demographic characteristics, sexual behaviors, substance use, and psychosocial factors. Methods: The meta-analysis followed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. The search included articles published between January 2018 and December 2022, obtained from the PubMed, ScienceDirect, and Scopus databases. The studies that were included in the analysis reported the proportion of MSM who demonstrated adherence to PrEP and underwent quality appraisal using the Newcastle-Ottawa Scale. Results: Of the 268 studies initially identified, only 12 met the inclusion criteria and were included in the final meta-analysis. The findings indicated that education (odds ratio [OR], 1.64; 95% confidence interval [CI], 1.12 to 2.40), number of sexual partners (OR, 1.16; 95% CI, 1.02 to 1.31), engaging in sexual activities with an human immunodeficiency virus-positive partner (OR, 1.59; 95% CI, 1.16 to 2.26), substance use (OR, 0.83; 95% CI, 0.70 to 0.99), and lower levels of depression (OR, 0.55; 95% CI, 0.37 to 0.82) were associated with higher rates of PrEP adherence among MSM. Conclusions: Despite these findings, further research is necessary to investigate PrEP adherence more comprehensively. The findings of this meta-analysis can be utilized to inform interventions aimed at improving PrEP adherence among MSM and provide directions for future research in this area.

• Journal of the Korean Society of Physical Medicine
• /
• v.19 no.1
• /
• pp.131-142
• /
• 2024

PURPOSE: This study was a systematic review and meta-analysis of the literature comparing the differences between task-oriented treadmill training and general treadmill training for stroke patients. METHODS: Literature published in the Cumulated Index to Nursing and Allied Health Literature (CINAHL), Embase, Physiotherapy Evidence Database (PEDro), and PubMed was reviewed. A total of 1,163 studies were initially retrieved, of which eight articles were included in the final review. A quality assessment of the included studies was conducted using the Risk of Bias (RoB) 2.0 tool, and Duval and Tweedie's trim and fill method was used to evaluate publication bias. Data analysis was performed using R studio 4.2.1. RESULTS: According to the quality assessment using RoB 2.0, three articles were evaluated as low risk, two as of some concern, and three as high risk. The overall effect size of task-oriented tradmill training was .35. Regarding gait function, the values were .76, .25, and .40, respectively, for gait endurance, gait speed, and gait pattern. According to Duval and Tweedie's trim and fill method, no publication bias was observed. CONCLUSION: Study findings indicate that task-oriented treadmill training is the most effective intervention for improving gait endurance in patients with stroke. Therefore, applying this intervention to patients with stroke in the community is recommended.

• Korean Journal of Ecology and Environment
• /
• v.51 no.1
• /
• pp.40-59
• /
• 2018

This review summarizes the history of freshwater zooplankton research in Korean Society of Limnology and necessary future topics that are remain poorly investigated in South Korea based on main research topics of published articles focusing on lakes, reservoirs, rivers and wetland ecosystems. In Korea, a total 450 freshwater zooplankton species have been reported (85 species of cladocera, ca. 230 species of rotifera since 1939, and 138 species of copepoda), and they cover 10% of total zooplankton species list. In the present paper, we provide recent species list of zooplankton found in Korea and their taxonomic keys. Over periods of 45 years, there are 25 published papers for zooplankton biota in lentic ecosystems in Korean Journal of Ecology and Environment (KJEE). The ecology of zooplankton communities in rivers has focused on the mechanisms involved in regulating their abundance, diversity and spatio-temporal patterns of genus Bosmina and rotifers (genus Brachionus and Keratella) that are most frequently found from Korea. On the other hand, the studies on zooplankton in wetland has focused on Alona, Chydorus and Ceriodaphnia with special emphasis on their relationships with aquatic macrophytes. Even though studies on the freshwater ecosystem in Korea have a long history, a few of studies on zooplankton biota were conducted at rice paddy, Dumbeong and wetlands. During the last two decades, experimental advances in freshwater zooplankton ecology and understanding of structure and function of this biota were made from a series of articles mainly in journal of KJEE. For future studies, quantitative, experimental and interdisciplinary approaches would be key words to understand zooplankton ecology and their roles in aquatic ecosystems under changing environments, and we have suggested necessary zooplankton research fields and future directions.

• Journal of the Society of Disaster Information
• /
• v.19 no.3
• /
• pp.471-480
• /
• 2023

Purpose: This study intends to present a future research direction for military education by identifying and analyzing research trends in the field of education related to soldiers in academic research published in Korea. Method: In domestic academic papers published from 2000 to 2022, 269 final papers were selected from among the papers conducted on the subjects of 'soldiers' and 'education'. The final selected literature was analyzed by categorizing it into year, research subject, research method type, number of researchers, research topic, and research content. Result: First, since 2010, the number of studies has gradually increased, and 31 articles were published in 2021, with the largest number of studies. Second, the largest number of studies were conducted on the entire military, followed by the Army and Nursing Officers. Third, qualitative research methods were used a little more in research methods. Fourth, the number of researchers with two or more researchers was steadily increasing. Fifth, most of the research topics were development, design, and improvement. Sixth, in terms of detailed research contents, most of the studies were related to soldiers' spirit(mental force) education and military education and training. Conclusion: Through this study, it was confirmed that military education was studied in various subjects. The direction of future research should be in-depth research from various perspectives with a lot of interest in military education and safety.

• Journal of Society of Preventive Korean Medicine
• /
• v.19 no.1
• /
• pp.71-82
• /
• 2015

Objective : The purpose of this study is to present the desirable model for the promotion of care coordination between Korean Medicine and Western Medicine and develope the instrument to measure the level of coordination. Moreover, we verified the validity and reliability of the developed Instrument. Method : In this study, We developed the 16 items regarding care coordination in Korean Medicine and Western Medicine by literature review and expert interviews. In addition, we verified the validity and reliability of the instrument as a methodological research. Results : We developed two factors such as 'Inter-professional activities' and 'Organizational support' as the instrument to measure the level of care coordination, and each of seven, eight total of 15 measurement items are listed. Conclusion : Since the legal permission, the level and type of care coordination and the effects of them are needed to be checked. So, the measurement instrument driven by this study has a political signification in healthcare system specially in these times. In addition, by utilizing this instrument, we propose to perform a variety of future studies on the levels of healthcare coordination and related outcomes.

• Journal of Acupuncture Research
• /
• v.33 no.2
• /
• pp.201-210
• /
• 2016

Objectives : The serum creatine kinase(CK) level of Amyotrophic Lateral Sclerosis(ALS) patients suggests that it may be an independent prognostic factor for the survival of ALS. We report the changes of serum CK level of ALS patients treated by administering processed Glycyrrhiza uralensis extracts and Korean medical treatments. Methods : We provided an ALS patient with processed Glycyrrhiza uralensis extracts and Korean medical treatments including acupuncture, pharmacopuncture and herbal medicine. The serum CK level was checked every month. The changes of ALSFRS-R and MRC grade were checked every month for additional result. Results : The serum CK level as the prognostic factor for the survival of ALS gradually decreased for three months. However, ALSFRS-R decreased by two points at the second trial. MRC rate had no change for three months. Conclusion : Combined administration of processed Glycyrrhiza uralensis extracts and Korean medical treatment could be meaningful possibilities in the treatment of ALS. We should conduct further studies to solve the limitations of this case study.

• Molecular & Cellular Toxicology
• /
• v.4 no.3
• /
• pp.230-234
• /
• 2008

Epidemiological studies demonstrate an adverse effect of several environmental and occupational exposures on male sex hormone. Bisphenol A (BPA) is a weak estrogen and a widely used industrial chemical. Epoxy resin painters may be continuously exposed to BPA at high concentrations. The effect of occupational exposure of BPA on male reproduction was examined by measuring the urinary BPA, testosterone and gonadotropic hormones of epoxy resin painters in the shipyard. The painters had significantly higher concentrations of urinary BPA (2.61${\pm}$1.08 ${\mu}g$/g creatinine) than controls (1.38${\pm}$0.5 9 ${\mu}g$/g creatinine). In serum, the testosterone level of painters was significantly decreased but the luteinizing hormone (LH) and follicle-stimulating hormone (FSH) levels of painters were significantly higher than controls. Occupational exposure to BPA influences testosterone and gonadotropic hormones in male workers.

• The Journal of Korean Society for School & Community Health Education
• /
• v.16 no.3
• /
• pp.17-29
• /
• 2015

Objectives: The purpose of this study is to examine the trend of adolescent's smart phone addiction researches from 2012 to 2014 in Korea, and to propose further study for prevention of adolescent's smart phone addiction. Methods: Subjects were 169 researches about adolescent's smart phone addiction from 2012 to 2014 in Korea, and the theme was summarized as following: variables associated with adolescent's smart phone addiction, prevention and intervention strategies of it, the status and development of adolescent's smart phone addiction scale, awareness and prevention of smart phone addiction. Results: As a result of this study, 63.3% were as the most source of researches in 2014, and master's thesis was 74.6 percent. According to the theme of research, the most effects on smart phone addition is self-control and parenting and the most relational variables with smart phone addition are anxiety and parenting. The most affected by smart phone addiction is adaption of school life and conversational breakdown. The studies about prevention of smart phone addiction and intervention examine the effect of therapy program and group consultation. Conclusions: The educational program for using smart phone should be made and applied for preventing adolescent's smart phone addiction.