• Proceedings of the KSME Conference
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• 2007.05a
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• pp.296-299
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• 2007

KAERI is in the process of carrying out the Nuclear Hydrogen Development and Demonstration (NHDD) Program. The indirect cycle gas cooled reactors that produce heat at temperatures in the order of $950^{\circ}C$ are being considered in the NHDD program. For the indirect gas cooled reactors, the intermediate hear exchanger (IHX) and hot gas duct (HGD) are the main components. For the NHDD program we are in the process of establishing a conceptual design of the IHX and HGD. The pre-conceptual design activities in this study dealt with a preliminary design of the IHX and the HGD including strength and thermal expansion evaluation of the main components.

• The Korean Journal of Nuclear Medicine
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• v.35 no.6
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• pp.352-363
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• 2001

Purpose: To investigate ictal hyperperfusion patterns during semiologic progression of seizures, we performed SPECT subfraction in 50 patients with temporal lobe epilepsy (TLE). Materials and Methods: The patients were categorized Into five groups according to semiologic progression during ictal SPECT (group-1 having only aura; group-2 haying motionless staling with or without aura; group-3 having motionless staring and then automatism with or without aura; group-4 having motionless staring and then dystonic posturing with or without aura and automatism; group-5 having motionless staring, automatism, then head version and generalized seizures with or without aura and dystonic posturing). Results: In group-1, three patients showed ipsilateral temporal hyperperfusion and two had bilateral temporal hyperperfusion with ipsilateral predominance. In group-2, three (42.9%) patients showed bilateral temporal hyperperfusion with unilateral predominance and four (57.1%) revealed insular hyperperfusion of epileptic side. In group-3, 15 patients (88.2%) showed bilateral temporal hyperperfusion with unilateral predominance and 12 (70.6%) insular hyperperfusion. In group-4, 11 patients (84.6%) showed basal ganglia hyperperfusion on the opposite hemisphere to the side of the dystonic posturing. en group-5, there were multiple hyperperfusion areas in the frontal, temporal and basal ganglia regions. However, the injection times of radiotracer in five groups were relatively short and similar. Conclusions: The semiologic progression in TLE seizures were related to the propagation of hyperperfusion from ipsilateral temporal lobe to contralateral temporal lobe, insula, basal ganglia, and frontal lobe. Not only the radiotracer injection time but also semiologic progression after the Injection was significant in determining hyperperfusion pattern of ictal SPECT.

• BMB Reports
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• v.54 no.5
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• pp.266-271
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• 2021

Estrogen-related receptor γ (ERRγ), a member of the orphan nuclear receptor family, is a key mediator in cellular metabolic processes and energy homeostasis. Therefore, ERRγ has become an attractive target for treating diverse metabolic disorders. We recently reported that ERRγ acts as a negative regulator of osteoclastogenesis induced by receptor activator of nuclear factor-κB ligand (RANKL). In the present study, we explored the effects of an ERRγ-specific modulator, GSK5182, on ERRγ-regulated osteoclast differentiation and survival. Interestingly, GSK5182 increased ERRγ protein levels much as does GSK4716, which is an ERRγ agonist. GSK5182 inhibited osteoclast generation from bone-marrow-derived macrophages without affecting cytotoxicity. GSK5182 also attenuated RANKL-mediated expression of cFos and nuclear factor of activated T-cells cytoplasmic 1 (NFATc1), pivotal transcription factors for osteoclastogenesis. Arrested osteoclast differentiation was associated with reduced RANK expression, but not with the M-CSF receptor, c-Fms. GSK5182 strongly blocked the phosphorylation of IκBα, c-Jun N-terminal kinase, and extracellular signal-regulated kinase in response to RANKL. GSK5182 also suppressed NF-κB promoter activity in a dose-dependent manner. In addition to osteoclastogenesis, GSK5182 accelerated osteoclast apoptosis by caspase-3 activation. Together, these results suggest that GSK5182, a synthetic ERRγ modulator, may have potential in treating disorders related to bone resorption.

• Structural Engineering and Mechanics
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• v.4 no.2
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• pp.139-148
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• 1996

Vector algorithms and the relative importance of the four basic modules (computation of element stiffness matrices, assembly of the global stiffness matrix, solution of the system of linear simultaneous equations, and calculation of stresses and strains) of a finite element computer program for inelastic analysis of reinforced concrete shells are presented. Performance of the vector program is compared with a scalar program. For a cooling tower problem, the speedup factor from the scalar to the vector program is 34 for the element stiffness matrices calculation, 25.3 for the assembly of global stiffness matrix, 27.5 for the equation solver, and 37.8 for stresses, strains and nodal forces computations on a Gray Y-MP. The overall speedup factor is 30.9. When the equation solver alone is vectorized, which is computationally the most intensive part of a finite element program, a speedup factor of only 1.9 is achieved. When the rest of the program is also vectorized, a large additional speedup factor of 15.9 is attained. Therefore, it is very important that all the modules in a nonlinear program are vectorized to gain the full potential of the supercomputers. The vector finite element computer program for inelastic analysis of RC shells with layered elements developed in the present study enabled us to perform mesh convergence studies. The vector program can be used for studying the ultimate behavior of RC shells and used as a design tool.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.11 no.2
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• pp.157-178
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• 2013

This study gives a conceptual and basic direction to develop a URL (underground research laboratory) program for establishing the performance and safety of a deep geological disposal system in Korea. The concept of deep geological disposal is one of the preferred methodologies for the final disposal of spent nuclear fuel (SNF). Advanced countries with radioactive waste disposal have developed their own disposal concepts reasonable to their social and environmental conditions and applied to their commercial projects. Deep geological disposal system is a multi-barrier system generally consisting of an engineered barrier and natural barrier. A disposal facility and its host environment can be relied on a necessary containment and isolation over timescales envisaged as several to tens of thousands of years. A disposal system is not allowed in the commercial stage of the disposal program without a validation and demonstration of the performance and safety of the system. All issues confirming performance and safety of a disposal system include investigation, analysis, assessment, design, construction, operation and closure from planning to closure of the deep geological repository. Advanced countries perform RD&D (research, development & demonstration) programs to validate the performance and safety of a disposal system using a URL facility located at the preferred rock area within their own territories. The results and processes from the URL program contribute to construct technical criteria and guidelines for site selection as well as suitability and safety assessment of the final disposal site. Furthermore, the URL program also plays a decisive role in promoting scientific understanding of the deep geological disposal system for stakeholders, such as the public, regulator, and experts.

• Journal of Radiation Protection and Research
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• v.39 no.1
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• pp.65-69
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• 2014

The Korean nuclear industry has been influenced by Fukushima nuclear accident of Japan which occurred two years ago. With information about the accident mainly through mass media such as television or internet, most people are inclined to have a negative perception about nuclear and radiation. They have lack of proper understanding of the fact. Especially, Korean students being future generation have a very limited chance to learn about nuclear and radiation from their regular school curricula. To meet this need, the effectiveness of an extra curricula program is studied using a set of survey on the change of knowledge and perception on radiation, which has been conducted by providing a radiation experiencing program, developed for this study, to high school students in Daejeon area. As a result, a large number of students are found to have enhanced their knowledge on radiation, while some students have shown their positive change of perception on radiation. Based on this, further study may need to improve the survey method and to promote its application for the development of more diverse and systematic radiation experiencing programs. Moreover, better ways for synergy between education and public relations activities on radiation safety may need to be sought.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.25 no.9
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• pp.599-605
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• 2015

The revised U.S. Nuclear Regulatory Commission(NRC), Regulatory Guide(RG) 1.20, rev.3 requires the evaluation of the potential adverse effects from pressure fluctuations and vibrations on piping and components for the reactor coolant, steam, feedwater, and condensate systems. Detailed vibration analyses for the systems attached to the steam generator are very difficult, because these piping systems are very complicated. This paper suggests a screening method for the flow-induced vibration of acoustic resonances and pump-induced vibration of the piping systems attached to the steam generator in order to conduct the APR1400 comprehensive vibration assessment program. This paper seeks to address the areas such as potential vibration sources, and methods to prevent the occurrence of acoustic resonances and pump-induced vibration of piping systems attached to the steam generator, for conducting the APR1400 comprehensive vibration assessment program. The screening method in this paper will be used to estimate the flow-induced vibration of the piping systems attached to the steam generator for the APR1400.

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2005.11b
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• pp.165-175
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• 2005

Measurement of spent resin activity was initiated in 2004 in order to develop the C-14 removal technology for safe disposal. As part of this program, spent resins were sampled and measured in the in-station resin storage tank 2 at Wolsong Nuclear Power Plant Unit 1. At the time of sampling, the resins had been in storage tank from 3 to 23 years. Total 72 resin samples were sampled, which were collected from both man-hole (68 samples) and test-hole (4 samples) in the in-station resin storage tank 2. They were separated into liquid, activated carbon, zeolite, and spent resin. The spent resins were oxidized with sample oxidizer and analyzed for C-14. Ten of collected mixed resin samples were separated by density into cation and anion resins using a sugar solution. The C-14 concentration in anion exchange resin was approximately 2 times higher than in the mixed resin. The average concentration of C-14 in the cation/anion mixed exchange resin was $460\;GBq/m^3$ from test-hole and $53.1\;GBq/m^3$ from man-hole. We have found that concentration of C-14 in the spent resin is about from 0.4 to $1,321\;GBq/m^3$. So it could be a problem, when dispose of at a repository, since there is a disposal limit of $222\;GBq/m^3$. This means we should develop the C-14 removal technology.

• Strategy21
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• s.31
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• pp.5-26
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• 2013

The South Korean society has experienced many changes since the sinking of ROKS Cheonan. The government reviewed its defense posture and adopted the 5·24 Measure in its relations with North Korea. As a result, the people of South Korea became more conscious of security situations on the Korean peninsula while North Korea's economy suffered badly. Meanwhile, the South Korean government has taken a flexible stance toward North Korea in terms of exchange and cooperation since September 2011. The flexible stance was to manage inter-Korea relations in a stable manner and relieve the hardships of the North Korean people while preserving the spirits and purposes of the 5·24 Measure. The UN Security Council adopted twenty-six resolutions and statements on North Korea since June 25, 1950. They include thirteen U.N. Security Council resolutions including those concerning nuclear weapons or missile programs, nine Presidential statements, and four press statements. Resolution 82, the first U.N. resolution on North Korea, came when the Korean War broke out. Resolution 825, the first one related to nuclear or missile programs, was adopted in response to North Korea's withdrawal from the NPT. Apart from these U.N. resolutions, the United States has imposed separate sanctions against North Korea. North Korea's nuclear weapons program can be considered in comparison with that of Iran in terms of the consequences they create for the regional security. The Security Council has adopted six resolutions on Iran so far. One should note that the resolutions on Iran have had much stronger sanctions compared to those imposed on North Korea. That is, while the North Korea case may be viewed as a more serious threat to international security from the perspective of nuclear weapons development or proliferation, tougher sanctions have been placed on Iran. There are two approaches that South Korea should take in addressing the related issues. First, we should aim to reduce the gap between sanctions imposed on Iran and North Korea. It is difficult to understand that a country with more serious problems is rewarded with lighter sanctions. We should take measures through the Security Council Sanctions Committee to make individuals and groups in North Korea that play a central role in developing nuclear weapons and missiles subject to additional sanctions. Second, we have to change. Other countries in the international community have become tired of North Korea's nuclear issue and now they look to South Korea for initiative. We should correctly understand this current situation and play a leading role within our capacity. Knowingly and unknowingly, the notion that the North Korean nuclear issue may be left to South Korea has been spread around the international community. Although the situation is grave, we should try to open a new horizon in ushering in the unification era by taking the initiative with confidence that there is a looming hope ahead of us. For these tasks, we should stop thinking in the old way that has been ossified for the last two decades. We should not be pushed around by neighboring great powers in dealing with North Korea related issues anymore; we should take the initiative with resolution that we will play our role at the center of four great powers and with confidence that we can do it. Based on the confidence that the Republic of Korea has become a country with enough capacity to take the initiative, we should establish a 'National Grand Strategy' representing South Korea's strategic vision that the unification is the ultimate solution to the problems related to North Korea's nuclear weapons program.

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2005.11a
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• pp.221-228
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• 2005

The objectives of this paper are to present the general features of the current IAEA programs and their future prospects in the fields of the nuclear fuel cycle and the related materials technologies thus responding to a need to achieve a consolidated understanding of the Agency's programs for an effect ive implementation of the respective national R&D projects in Korea. During the development of the Agency's programs for 2005-2007 in the aforementioned fields. it is foreseen that an considerable attention will be attributed to the concepts, models and opportunities for optimizing the fuel cycle, mining the raw materials, re-using the materials and reducing the waste arisings (e.g. through Partitioning and transmutation), all of which, will Include an enhanced consideration for proliferation and security concerns.