• 대한전자공학회논문지TC
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• 제41권12호
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• pp.85-91
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• 2004

정지 위성을 이용하여 양방향 통신을 위한 이동 단말 안테나의 구조는 송신 시스템과 수신 시스템으로 구성된다. 송신 시스템은 위성으로 신호를 전송하기 위한 송신부이며, 반면 수신 시스템은 위성으로부터의 신호를 수신하는 수신부 외에 위성추적을 위한 위성추적 제어부로 구성된다. 한편, 이동 환경에서 정지 위성을 이용한 양방향 통신은 다른 위성 통신에 피해가 없도록 국제적 기준의 안테나 패턴 특성과 안정적인 위성 추적이 요구된다. 본 논문에서는 Ku 대역 정지 위성의 양방향 통신 서비스를 위하여 제작된 이동형 위상 배열 안테나의 안테나 패턴과 안정적인 위성 추적이 가능하도록 하는 위성 추적 제어부를 포함한 수신 시스템의 설계 및 제작 특성에 대해 살펴보았다.

• 한국콘텐츠학회논문지
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• 제16권7호
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• pp.659-666
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• 2016

현대 사회에서 색채가 인간에게 미치는 영향은 정신적 심리적 측면에서 중요한 요소로 나타나고 있다. 색채는 시지각적으로 인간의 마음에 일어나는 감정과 정서를 연출하여 메마른 감성을 치유하며, 환경은 표현된 색채에 따라 삶의 가치를 높여 주는 역할을 한다. 본 연구에서는 금속의 단조로운 색채표현을 해소하기 위한 측면으로 금속 장신구에 옻칠과 포슬린150물감을 사용하여 표현하는 방법을 응용시켜 다양한 색채변화를 나타내었다. 옻칠과 포슬린150물감의 금속시편을 제작하고 비교 분석하여 장 단점의 결과로 도출하였다. 장점은 이를 접목하는 방법은 금속 색채표현의 일반적인 방법에 비해 색채효과를 다양하게 표현할 수 있었고, 표면 코팅 역할을 하므로 기물의 변색을 방지하여 가변적 문제점을 보완해 줄 수 있었다. 단점은 옻칠은 체질에 따른 옻오름 현상이 나타나고, 포슬린150페인팅은 화학성분으로 식기류에 사용하면 건강에 해로울 수 있다. 이를 참고하여 작품에 적용하여 예술성과 실용성 구현에 기여하고자 한다.

• 대한의생명과학회지
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• 제3권1호
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• pp.1-9
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• 1997

대부분의 포유동물들에서 수정전에 정자의 첨체반응이 일어난다고 알려져 있으며 첨체반응에서 $Ca^{2+}$ 이 중요한 역할을 한다고 알려져 있다. 단백질 또한 정자의 생리적 역할에 중요한 요소로 작용한다고 보고되고 있다. 본 실험에서는 동면동물의 부정소에서 정자성숙과정을 비교 관찰하고 성숙 과정에 있어 $Ca^{2+}$ 농도와의 연관성을 규명하고 정자성숙 전, 후에 정자성숙에 영향을 미치는 $Mg^{2+}$-ATPase, lactate dehydrogenase의 작용을 비교, 분석하였다. 그 결과 다음과 같은 결과를 얻었다. 대표적 동면동물인 박쥐의 경우 활동기에 다른 동면동물인 햄스터, 항온동물인 생쥐와 마찬가지로 부정소미에서 정자성숙과정을 거쳤으며 교미시 대부분의 정자는 부정소미에서 더욱 활발한 운동성을 보였으며 부정소미 말에서 수정능획득 과정을 거치는 것으로 관찰되었다. 그러나 동면동물의 환경 조건 특히 온도의 변화가 부정소에서의 정자성숙과정에 영향을 주는지에 대해서는 더 자세한 연구가 필요하다고 사료된다.

• BMB Reports
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• 제44권11호
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• pp.753-757
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• 2011

Heme oxygenase-1 (HO-1), an inducible enzyme with broad tissue expression, is wel1-regulated in response to hematopoietic stress and preserves vascular homeostasis. We investigated the involvement of HO-1 in HL-60 cell differentiation. Dimethyl sulfoxide (DMSO) completely decreased HO-1 expression in a time-dependent manner, but clearly induced HL-60 cell differentiation, as evidenced by a marked increase in CD11b expression. Interestingly, zinc protoporphyrin (ZnPP), a strong inhibitor of HO-1, induced HL-60 cell differentiation. In contrast, treatment with cobalt protoporphyrin (CoPP), an activator of HO-1, decreased CD11b expression. Additionally, ZnPP down-regulated HO-1 protein expression in HL-60 cells, whereas CoPP induced upregulation. These results suggest that HO-1 might have a negative function in DMSO-induced HL-60 cell differentiation. This study provides the first evidence that HO-1 plays an important role in DMSO-induced HL-60 cell differentiation.

• 간호행정학회지
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• 제22권2호
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• pp.109-118
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• 2016

Purpose: The aim of this study was to analyze relationships between perfectionism, burnout, and emotional intelligence in APN and to identify the mediating effect of emotional intelligence on the relationship between perfectionism and burnout. Methods: A structured self-report questionnaire was used to measure perfectionism, burnout, and emotional intelligence. Data were collected from 121 APN working in five advanced general hospitals and two general hospitals. Data were analyzed using descriptive statistics, Independent t-test, One-way ANOVA, Mann-Whitney U test, Pearson correlation and Hierarchical multiple regression with the SPSS/WIN 22.0 program. Results: Mean scores for each variable were: perfectionism 3.57 (on a 5-point scale), burnout 3.32 (on a 7-point scale), and emotional intelligence 5.00 (on a 7-point scale). Self-oriented perfectionism had a positive correlation with burnout, as did socially prescribed perfectionism. Emotional intelligence was a significant variable reducing burnout, as it also had a reverse buffering effect on the relationship between self-oriented perfectionism and burnout. Explanatory power of the final model based on variables was 34%. Conclusion: The results of this study suggest a mediating direction regarding burnout by demonstrating that emotional intelligence plays a direct and reverse buffering role to self-oriented perfectionism, which can be used to reduce burnout in APN.

• 한국발생생물학회지:발생과생식
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• 제22권4호
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• pp.341-350
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• 2018

Chemokines is a small protein that plays a major role in inflammatory reactions and viral infections as a chemotactic factor of cytokines involved in innate immunity. Most of the chemokines belong to the chemokine groups CC and CXC. To investigate the immune system of the olive flounder (Paralichthys olivaceus), an expression pattern specifically induced in the early developmental stages of analysis is examined using qRT-PCR. We also examined tissue-specific expression of both CC and CXC chemokine in healthy olive flounder samples. CC and CXC chemokine shows increased expression after immune-related organs are formed compared to expression during early development. CC chemokine was more highly expressed in the fin, but CXC chemokine showed higher expression in the gills, spleen, intestines, and stomach. Spatial and temporal expression analysis of CC and CXC chemokine were performed following viral hemorrhagic septicemia virus (VHSV) infection. CC chemokine showed high expression in the gills, which are respiratory organs, whereas CXC chemokine was more highly expressed in the kidneys, an immune-related organ. These results suggest that CC and CXC chemokine play an important role in the immune response of the olive flounder, and may be used as basic data for the immunological activity and gene analysis of it as well as other fish.

• International Journal of Advanced Culture Technology
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• 제9권3호
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• pp.259-264
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• 2021

In modern socity, online communication plays a vital role in social interaction of communicities. It is so common for online users to see display advertisements online while surting the Net. Specifically, most web banners diaplayed on portral sites consist of words, phrase, and sentences. Considering that the primary purpose of adversiting is persuation, the advertisement such as web banners is an examplary case to show the interaction among pragmatics, translation and advertising because the linguistic expressions employed in the banners represent its pragmatic use, leading to persuation and functioning as a communicative tool for the smooth communication between source text producers (adversisers) and target audience (online users). This can be part of the so-called translation process. In particular, we can easily witness the use of English words in web banners. Thus, this paper looks at web banners displayed on major four portal sites-Naver, Daum, Nate, and Zum, giving a special attention to the content contained in the web banners as well as the use of English words. As s result, we found that the frequencies of English words in each portal site were higher when the advertised products were targeting young online users, whereas the frequencies were lower when the users are older group than young people. The finding supports the prgramatic perspective that linguistic expressions are understood in social contexts and shows the so-called translation process which involves a shift from semantic meaning of words to their pragmatic use. Finally, we can conclude that the interaction is possible when we have the framework where translation, pragmatics, and advertising are all communitative components for social interaction within social contexts.

• Journal of Medicine and Life Science
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• 제15권2호
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• pp.67-71
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• 2018

Neuronal excitotoxicity induces mitochondrial dysfunction and the release of proapoptotic proteins. Excitotoxicity, the process by which the overactivation of excitatory neurotransmitter receptors leads to neuronal cell death. Neuronal death by excitotoxicity was related to neuronal degenerative disorders and hypoxia, results from excessive exposure to excitatory neurotransmitters, such as glutamate. Glutamate acts at NMDA receptors in cultured neurons to increase the intracellular free calcium concentration. Therefore endogenous glutamate may be a key factor to regulate neuronal cell death via activating $Ca^{2+}$ signaling. For this issue, we tested some conditions to alter intracellular $Ca^{2+}$ level in dissociated hippocampal neurons of rats. Cultured hippocampal neuron were treated by KCl (20 mM), $CaCl_2$ (3.8 mM) and glutamate ($5{\mu}M$) for 24 hrs. Interestingly, The Optical Density of hippocampal neurons was increased by high KCl application in MTT assay data. This enhanced response by high KCl was dependent on synaptic $Ca^{2+}$ influx but not on intracellular $Ca^{2+}$ level. However, the number of neurons seemed to be not changed in Hoechst 33342 staining data. These results suggest that enhancement of synaptic activity plays a key role to increase mitochondrial signaling in hippocampal neurons.

• The Korean Journal of Physiology and Pharmacology
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• 제25권2호
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• pp.139-146
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• 2021

Mitochondrial NADP+-dependent isocitrate dehydrogenase 2 (IDH2) produces NADPH, which is known to inhibit mitochondrial oxidative stress. Ureteral obstruction induces kidney inflammation and fibrosis via oxidative stress. Here, we investigated the role and underlying mechanism of IDH2 in unilateral ureteral obstruction (UUO)-induced kidney inflammation using IDH2 gene deleted mice (IDH2-/-). Eight- to 10-week-old female IDH2-/- mice and wild type (IDH2+/+) littermates were subjected to UUO and kidneys were harvested 5 days after UUO. IDH2 was not detected in the kidneys of IDH2-/- mice, while UUO decreased IDH2 in IDH2+/+ mice. UUO increased the expressions of markers of oxidative stress in both IDH2+/+ and IDH2-/- mice, and these changes were greater in IDH2-/- mice compared to IDH2+/+ mice. Bone marrow-derived macrophages of IDH2-/- mice showed a more migrating phenotype with greater ruffle formation and Rac1 distribution than that of IDH2+/+ mice. Correspondently, UUO-induced infiltration of monocytes/macrophages was greater in IDH2-/- mice compared to IDH2+/+ mice. Taken together, these data demonstrate that IDH2 plays a protective role against UUO-induced inflammation through inhibition of oxidative stress and macrophage infiltration.

• The Plant Pathology Journal
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• 제37권6호
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• pp.607-618
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• 2021

The pepper anthracnose fungus, Colletotrichum scovillei, causes severe losses of pepper fruit production in the tropical and temperate zones. RAC1 is a highly conserved small GTP-binding protein in the Rho GT-Pase family. This protein has been demonstrated to play a role in fungal development, and pathogenicity in several plant pathogenic fungi. However, the functional roles of RAC1 are not characterized in C. scovillei causing anthracnose on pepper fruits. Here, we generated a deletion mutant (𝜟Csrac1) via homologous recombination to investigate the functional roles of CsRAC1. The 𝜟Csrac1 showed pleiotropic defects in fungal growth and developments, including vegetative growth, conidiogenesis, conidial germination and appressorium formation, compared to wild-type. Although 𝜟Csrac1 was able to develop appressoria, it failed to differentiate appressorium pegs. However, 𝜟Csrac1 still caused anthracnose disease with significantly reduced rate on wounded pepper fruits. Further analyses revealed that 𝜟Csrac1 was defective in tolerance to oxidative stress and suppression of host-defense genes. Taken together, our results suggest that CsRAC1 plays essential roles in fungal development and pathogenicity in C. scovilleipepper fruit pathosystem.