• 한국보육학회지
• /
• 제18권3호
• /
• pp.123-140
• /
• 2018

본 연구는 전래동요에 기초한 음악놀이활동이 유아의 국악능력과 국악흥미도, 놀이성에 미치는 영향이 어떠한가를 분석해보는데 목적이 있다. 이를 위해 W시에 위치한 어린이집의 만 5세 두 학급의 유아 28명을 선정하여, 실험집단을 대상으로 전래동요에 기초한 음악놀이활동을 적용하였으며, 비교집단에는 가창 중심의 전래동요 지도와 누리과정에 기초한 주제 중심의 음악활동을 적용하였다. 수집된 자료를 토대로 두집단의 사전검사 점수를 공변인으로 한 공변량분석을 실시하였으며 분석결과, 전래동요에 기초한 음악놀이활동이 유아의 국악능력과 국악흥미도, 놀이성을 통계적으로 유의하게 향상시키는 것으로 나타났다. 연구의 결과는 음악놀이가 전래동요에 내재한 놀이성과 연계되어 국악교육을 위한 효과적인 교수방법으로 적용될 수 있음을 시사한다.

• Bulletin of the Korean Chemical Society
• /
• 제35권9호
• /
• pp.2625-2629
• /
• 2014

Platelets are anuclear discoid-shaped blood cells with key roles in human body. To understand the mechanisms of their activation process, it is required to have analytical imaging techniques capable of acquiring platelet images under fully hydrated conditions. Herein, for the first time, we demonstrate the capability of synchrotron-based transmission X-ray microscopy (TXM) to study platelets (resting and ADP activated) under hydrated and air-dried conditions. To confirm the biological imaging capability of TXM, fixed platelets were imaged and compared with whole mount electron microscopy (EM) images. TXM provided morphological information with sufficient spatial resolution with simple and quick sample preparation procedure. We also observed temporal changes during the platelet activation, which initially had a discoid shape (0 s), formed pseudopodia (30 s) and generated a network of fibrin (5 min). Our results clearly demonstrate the potential of TXM technique to study fully hydrated biological samples under in situ conditions.

• Radiation Oncology Journal
• /
• 제33권3호
• /
• pp.226-232
• /
• 2015

Purpose: Toxicity of mucosa is one of the major concerns of radiotherapy (RT), when a target tumor is located near a mucosal lined organ. Energy of photon RT is transferred primarily by secondary electrons. If these secondary electrons could be removed in an internal cavity of mucosal lined organ, the mucosa will be spared without compromising the target tumor dose. The purpose of this study was to present a RT dose reduction in near target inner-surface (NTIS) of internal cavity, using Lorentz force of magnetic field. Materials and Methods: Tissue equivalent phantoms, composed with a cylinder shaped internal cavity, and adjacent a target tumor part, were developed. The phantoms were irradiated using 6 MV photon beam, with or without 0.3 T of perpendicular magnetic field. Two experimental models were developed: single beam model (SBM) to analyze central axis dose distributions and multiple beam model (MBM) to simulate a clinical case of prostate cancer with rectum. RT dose of NTIS of internal cavity and target tumor area (TTA) were measured. Results: With magnetic field applied, bending effect of dose distribution was visualized. The depth dose distribution of SBM showed 28.1% dose reduction of NTIS and little difference in dose of TTA with magnetic field. In MBM, cross-sectional dose of NTIS was reduced by 33.1% with magnetic field, while TTA dose were the same, irrespective of magnetic field. Conclusion: RT dose of mucosal lined organ, located near treatment target, could be modulated by perpendicular magnetic field.

• 대한수학교육학회지:수학교육학연구
• /
• 제25권4호
• /
• pp.631-655
• /
• 2015

유아수학교육의 중요성은 날로 강조되고 있으며, 따라서 초등수학과의 연계성 확보에 대한 관심 또한 증가하고 있다. 학교수학과는 별개로 연구되고 있는 유치원 수학을 수학과 교육과정에 포함시키는 이점에 근거하여, 수학과 교육과정 구성 체제를 초 중등의 학제가 아닌 유 초 중등의 학제에 따라 전개하는 가능성을 탐색하고 그 구체적인 내용 선정을 시도하는 것이 본 연구의 목적이다. 이를 위해 선행연구 결과를 기반으로 하고, 수학과 교육과정이 초중등이 아닌 유치원부터 시작하는, 이른바 K-12의 체제를 따르는 외국의 수학과 교육과정을 비교 분석하여 유치원과 초등학교 1학년의 내용 연계 양태를 파악하였다. 그 결과를 기초로, 학습 출발점의 원리, 중복 최소화의 원리, 전-개념을 위한 활동 중심의 원리, 초등 수학과 교육과정 준거의 원리에 따라 영역별로 내용을 선정하고 이를 통해 유 초 수학교육의 연계성 확보 및 차후 우리나라의 교육과정 변화에 대비하기 위한 시사점을 도출하였다.

• 한국수정란이식학회지
• /
• 제33권3호
• /
• pp.169-175
• /
• 2018

It has been claimed that artificial insemination (AI) of cows with frozen-thawed semen treated with commercially produced kits, Wholemom (in favour of female gender) increases the birth chance of calves with desired sex ratio by approximately 85% without decrease of pregnancy rates. Hence, this study was conducted to investigate the efficacy of wholemom kits as combined with frozen-thawed bovine semen during in vitro fertilization on the in vitro fertilization and developmental efficiency and sex ratios such as some reproductive parameters in bovine. For this, 1,737 oocytes were in vitro fertilized and developed. Agglutination effects on bovine after treatment of Wholemom kit were observed by time passage and dose respectively. To determine sex of embryos, Bovine embryo Y-specific gene primers(ConEY) and Bovine specific universal primer(ConBV) were used as multiple PCR method. Fertilization rate of wholemom-treated group was significantly lower than its of control group[66.9% (1,156/1,737) in Wholemom-treated group; 75.0% (610/813) in control group]. However, developmental rate after fertilization of both wholemom-treated and control groups were not significantly different [26.1% (404/1,156) in Wholemom-treated group; 27.4% (224/610) in control group]. Sex ratio of in vitro fertilized embryo with frozen-thawed semen treated with wholemom kit was determined by multi PCR. Female ratio in wholemom-treated group [85.4% (173/201)] was significantly higher than its of control group [47.2% (66/141)]. In conclusion, wholemom treatments of semen used in the in vitro fertilization and development of bovine oocytes provided increase in female ratio with decrease of fertilization rate.

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• 제18권2호
• /
• pp.94-99
• /
• 2015

Purpose: A mother's working environment is believed to be a major determinant of exclusive breastfeeding (EBF) practice. We aimed to define the influence of a facility dedicated to breastfeeding and a breastfeeding support program at the workplace on breastfeeding practice. Methods: A cross-sectional study was performed in five workplaces. The inclusion criteria were female workers whose last child was between 6 and 36 months old. Observational data were obtained and a questionnaire was filled out. The World Health Organization definition for EBF was used. Results: Data from 186 subjects (74 office workers and 112 factory workers) were collected. Just over half (52%) of the mothers were between 20 and 46 years old, 75.3% had graduated from high school and university, 12.9% had more than two children and 36.0% owned a house. The prevalence of EBF during the last 6 months was 32.3%. A proper dedicated breastfeeding facility was available for 21.5% of the mothers, but only 7.5% had been in contact with a breastfeeding support program. The presence of a dedicated breastfeeding facility increased EBF practice almost threefold, by an odds ratio (OR) of 2.74 and a 95% confidence interval (CI) of 1.34-5.64 (p<0.05). Knowledge of the breastfeeding support program increased EBF practice by almost six times (OR, 5.93; 95% CI, 1.78-19.79) (p<0.05). Conclusion: Our findings suggest that Governments should make it obligatory for employers to offer a breastfeeding support program and a dedicated breastfeeding facility at the workplace as these simple measures significantly increase EBF.

• 한국임상수의학회지
• /
• 제32권5호
• /
• pp.445-448
• /
• 2015

5개월령 코리안 숏헤어 새끼 고양이(몸무게 1.7 kg)가 상부호흡기 증상, 얼굴과 발/발바닥의 궤양과 부종 및 파행을 주증으로 내원하였다. 실험실 검사상, 백혈구감소증, 림프구 감소증, 췌장염 및 칼리시바이러스 감염증이 확인되었다. 진단은 고독성 칼리시바이러스 감염증에 대한 특이 임상증상과 PCR을 통한 칼리시바이러스 동정 및 다른 상부호흡기 감염을 배제함으로써 내려졌다. 상부호흡기 증상완화와 이차 감염에 대한 처치 및 보조요법을 약 한 달간 실시하였고, 환자는 이러한 치료를 통해 임상증상이 크게 개선되었다. 본 증례는 고독성 고양이 칼리시바이러스에 대한 첫 번째 발병증례이다.

• 지능정보연구
• /
• 제11권1호
• /
• pp.65-93
• /
• 2005

미술진단을 위한 전문가 시스템에는 (1)그림의 특징 (2) 환자의 심리증상 (3)그림 특징과 환자 심리증상 간의 관계 (4) 전문가의 진단과정 (5)지식의 표출 및 표현 방법 둥 다양한 분야에서 광범위한 지식이 필요하다. 이 지식들은 현장의 그림진단 치료사와 함께, 심리학자, 심리치료사, 그리고 미술진단을 컴퓨터에 구현할 지식공학자들로부터 얻어진다. 전문가는 다양한 요인들을 복합적으로 고려하는 매우 복잡한 진단과정을 거치며, 관련되는 방대한 지식들은 성격상 모호하고, 일관성이 부족하며, 때에 따라서는 상충적이기도 하다. 이 논문에서는 전문가의 진단과정을 모델링하여, 전문가 시스템의 구조를 설립하고, 지식들을 분석하여 분류한다. 분류에 따라 지식 획득과 표현에 적합한 방법을 선정하며, 온톨로지(ontoloty) 개념에 의한 프로티지(Protege) 2000을 도구로 사용하여 이 지식들을 체계적으로 정리한다. 실제 예제를 통하여 이 시스템의 사용가능성과 적합성을 보인다.

• 한국가금학회지
• /
• 제40권2호
• /
• pp.91-96
• /
• 2013

FABPs, 15 kDa organic substances, are small intracellular proteins which have a primary role to regulate fatty acid uptake and intracellular transport. This study was conducted to identify SNPs in the two FABP family genes and their associations with the body weight traits in Korean native chicken (KNC). Two SNPs, namely g.508C>T of FABP3 gene and g.285C>T of FABP4 gene, have been genotyped by using PCR-RFLP method. The results showed that FABP3 was significantly associated with body weight at birth, body weights at 12 to 20 weeks, and also slaughter weight. Moreover, the g.285C>T SNP of FABP4 gene was not associated with any body weight traits. These results suggested that the g.508C>T SNP of FABP3 genes can be used as molecular markers to select KNC having desirable body weights.

• 한국가금학회지
• /
• 제40권2호
• /
• pp.157-162
• /
• 2013

Both ODC and PRDM16 genes were known to be associated with body weight traits in chicken. These two genes were located on GGA3 and GGA21, respectively, where the QTLs of body weights are located. Therefore, the objectives of this study were to identify the SNPs in these two genes and their associations with body weight traits in Korean native chicken. Fluidigm Dynamic Array integrated fluidic circuits (IFCs) assay was used to genotype 7 SNPs consisting g.-353C>T, g.2136A>G, g.2524T>C, g.3607C>T SNPs of the ODC gene, and g.182216C>T, g.182290A>T, g.182491A>T SNPs of the PRDM16 gene. Statistical analysis showed that g.2136A>G SNP of the ODC was associated with body weight at 20 weeks of age and slaughter weight, and g.3607C>T SNP of the ODC was associated with body weight at 2 weeks of age. Association between g.182216C>T SNP of the PRDM16 and body weight at 12 weeks of age has also been revealed. In addition, g.182491A>T SNP of PRDM16 has significant correlation with body weight (BW) at 8 weeks, BW at 10 weeks and BW at 14 weeks of age. These results suggested that both ODC and PRDM16 could be strong candidate genes for body weight traits in Korean native chicken.