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Optimization Design of Solar Water Heating System based on Economic Evaluation Criterion using a Genetic Algorithm (유전알고리즘 이용 경제적 평가기준에 따른 태양열급탕시스템 최적화 설계에 관한 연구)

  • Choi, Doosung;Ko, Myeongjin;Park, Kwang-Tae
    • Journal of the Korean Solar Energy Society
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    • v.36 no.5
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    • pp.73-89
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    • 2016
  • To assure maximum economic benefits and the energy performance of solar water heating systems, the proper sizing of components and operating conditions need to be optimized. In recent years, a number of studies to design optimally solar water heating systems have been tried. This paper presents a design method for optimizing the various capacity-related and installation-related design variables based on life cycle cost using a genetic algorithm. The design variables considered in this study included the types and numbers of solar collector and auxiliary heaters; the types of storage tanks and heat exchangers; the solar collector slope; mass flow rates of the fluid on the hot and cold sides. The suggested method was applied for optimizing a solar water heating system for an elementary school in Seoul, South Korea. In addition, the effectiveness of the proposed optimization method was assessed by analyzing the obtained optimal solutions of six case studies, each of which was simulated with different solar fractions. It is observed that a trade-off between the equipment cost and the energy cost results in an optimal design that yields the lowest life cycle cost. Therefore, it could be helpful to apply the optimal solar water heating system by comparing the various design solutions obtained by using the optimization method instead of the engineer's experience and intuition.

Lack of Influence of MGMT Codon Leu84Phe and Codon Ileu143Val Polymorphisms on Esophageal Cancer Risk in the Kashmir Valley

  • Shah, Mohd A.;Shaffi, Sheikh M.;Lone, Ghulam Nabi;Jan, Syed Mudassar
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.7
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    • pp.3047-3052
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    • 2012
  • The enzyme encoded by the MGMT gene is involved in the repair of alkylated lesions formed in DNA by carcinogenic nitrosamines. Since dietary items consumed by the Kashmiri population contain high concentrations of these agents, it is biologically plausible that MGMT polymorphic variants may be associated with their risk of esophageal cancer. The present study was performed to assess whether non-synonymous SNPS at codon Leu84Phe and codon Ileu143Val of the MGMT gene, close to the active site of the protein, might be linked to predisposition of Kashmiris to esophageal cancer. Genotyping was carried out by polymerase chain reaction-restriction fragment length polymorphism on 92 cases and 77 healthy controls. Codon 84 and codon 143 SNPs of the MGMT gene were not associated with any increase in risk. While the frequency of the Phe allele at codon 84 in cases was (0.16), slightly higher than controls (0.12), the difference was not statistically significant. Similarly, the frequency of Valine allele in cases at codon 143 (0.08) and controls (0.09) was nearly equal. Moreover, no significant association of MGMT genotypes with the clinicopatholgic variables of esophageal cancer patients was observed. In conclusion, MGMT variants at codon 84 and codon143 may not be involved in the susceptibility of the Kashmiri population to esophageal cancer.

Effect of Intravenous Intraoperative Esmolol on Pain Management Following Lower Limb Orthopedic Surgery

  • Haghighi, Mohammad;Sedighinejad, Abbas;Mirbolook, Ahmadreza;Nabi, Bahram Naderi;Farahmand, Maral;leili, Ehsan Kazemnezhad;Shirvani, Masoumeh;Jahromi, Sina Khajeh
    • The Korean Journal of Pain
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    • v.28 no.3
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    • pp.198-202
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    • 2015
  • Background: Lack of proper control of acute postoperative pain often leads to lingering or chronic pain. Several studies have emphasized the role of beta-blockers in reducing postoperative pain. Esmolol is a selective short-acting beta-blocker that produces few side effects. The purpose of this study was to examine the effect of intravenous intraoperative esmolol on postoperative pain reduction following orthopedic leg fracture surgery. Methods: In a clinical trial, 82 patients between 20-65 years of age with tibia fractures and American Society of Anesthesiologists (ASA) physical status I & II who underwent surgery were divided into two groups. Group A received esmolol and group B received normal saline. Postoperative pain was measured at three time points: entering the recovery unit, and at 3 h and 6 h following surgery, using the Visual Analogue Scale (VAS). A P value of < 0.05 was considered significant. Results: Mean VAS scores at all three time points were significantly different between the two test groups (P = 0.02, P = 0.0001, and P = 0.0001, respectively). The consumption of pethidine was lower in group A than in group B (P = 0.004) and the duration of its effect was significantly longer in time (P = 0.026). Conclusions: Intravenous intraoperative esmolol is effective in the reduction of postoperative pain following leg fracture surgery. It reduced opioid consumption following surgery and delayed patient requests for analgesics.

Identification of Pedigree by Bovine Blood Typing in Holstein (젖소에 있어서 혈액형분석에 의한 혈통확인에 관한 연구)

  • 이장희;신형두;정호영;유충원;안병석;이수헌;정상원;김창원
    • Journal of Embryo Transfer
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    • v.9 no.2
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    • pp.197-205
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    • 1994
  • This experiment was carried out to clarify the pedigree identification from blood typing of 301 Hoisteins in National Animal Breeding Institute(N.A.B.I.). Twenty kinds of standard reagent standardized by Insternational Society for Animal Blood Group Research provied from KNC improvement center, N, L, C, F. were used as the reference reagents in this study. The highest frequency of antigenic facfors was obtained from X$_2$in blood typing of 301 Holsteins. The frequency of X$_2$ was 0.714.In A blood system, four kinds of phenogroups were observed. The gene frequencies of Al and Z' phenogroups were equally 0.027.This frequency was greatly lower than those of breeds of Southern European and Zebu cattle. In B blood Systern, nineteen kinds of blood type were appeared. The appearance frequency of Gx blood type was 0.259, whish was higher than the others. In C blood system, thirty kinds of blood type were observed. The appearance frequency of X$_2$ blood type was the highest(0.189). In F blood system, three kinds of alleles were detected. The gene frequency of F allele was higher than that of V(0.105). However, the frequency of F allele(0.327) was greatly lower than that of "- /- " allele. In S blood system, twelve kinds of blood type were appeared and showed sirnilar appearance frequencies except " - / - " allele. From the results of the pedigree identification from 8 sires and 28 progenies of them, the accuracy of pedigree identification was 92.9%.ification was 92.9%.

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Transgenic Tobacco Plant Expressing Environmental E. coli merA Gene for Enhanced Volatilization of Ionic Mercury

  • Haque, Shafiul;Zeyaullah, Md.;Nabi, Gowher;Srivastava, P.S.;Ali, Arif
    • Journal of Microbiology and Biotechnology
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    • v.20 no.5
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    • pp.917-924
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    • 2010
  • The practicability of transgenic tobacco engineered to express bacterial native mercuric reductase (MerA), responsible for the transport of $Hg^{2+}$ ions into the cell and their reduction to elemental mercury ($Hg^0$), without any codon modification, for phytoremediation of mercury pollution was evaluated. Transgenic tobacco plants reduce mercury ions to the metallic form; take up metallic mercury through their roots; and evolve the less toxic elemental mercury. Transformed tobacco produced a large amount of merA protein in leaves and showed a relatively higher resistance phenotype to $HgCl_2$ than wild type. Results suggest that the integrated merA gene, encoding mercuric reductase, a key enzyme of the bacterial mer operon, was stably integrated into the tobacco genome and translated to active MerA, which catalyzes the bioconversion of toxic $Hg^{2+}$ to the least toxic elemental $Hg^0$, and suggest that MerA is capable of reducing the $Hg^{2+}$, probably via NADPH as an electron donor. The transgenic tobacco expressing merA volatilized significantly more mercury than wild-type plants. This is first time we are reporting the expression of a bacterial native merA gene via the nuclear genome of Nicotiana tabacum, and enhanced mercury volatilization from tobacco transgenics. The study clearly indicates that transgenic tobacco plants are reasonable candidates for the remediation of mercurycontaminated areas.

A Study on the Formative Aesthetics and Modern Application of Traditional Korean Knots (전통 매듭의 조형미와 현대적 활용실태)

  • Kim, Bo-Young;Geum, Key-Sook
    • Journal of the Korean Society of Costume
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    • v.60 no.10
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    • pp.1-15
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    • 2010
  • A Korean knot is one of the ornamental elements that our ancestors used intimately in their daily lives, and the diverse forms and structural features of the Korean knot have sufficient creative and aesthetic value for it to be recognized as one of beautiful products that was relished by individuals of the times. Starting from two strands, Korean knots make unique forms as they are overlapped or plaited, crossing each other in many ways. The forms of Korean knots were given names such as "nabi maedeup"(butterfly knots) and "gukwa maedeup" (chrysanthemum knots), in reference to things in the surrounding environment that were perceived as being similar in their appearance. It is considered that with their unique structure, such Korean knots may provide a good motif for creative design. As well, it is believed that combining the traditional beauty of Korean knots with a contemporary sensibility will lead to the creation of truly forward-looking design. Against this backdrop, this study aims to inquire into and analyze the formative characteristics and aesthetics of Korean knots, with an eye to their use in future design. In addition, it aims to help to put such historical knotting practices into practical and functional use in the future, through a study of previous uses of historical knotting practices with a modern sensibility. It is thus expected that this work will contribute to the inheriting and development of traditional culture, and ultimately to enhancing the status of Korean design in the world.

Estimation of Genetic Components of Variance in Biparental Progenies of Bivoltine Silkworm (Bombyx mori L.)

  • Malik, Gulam Nabi;Sofi, Abdul Majeed;Haque Rufaie, Syed Zia;Singh, Tejender Paul;Aijaz, Mohammad;Malik, Manzoor Ahmad;Dar, Habib Ullah
    • International Journal of Industrial Entomology and Biomaterials
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    • v.9 no.2
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    • pp.279-281
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    • 2004
  • Components of genetic variation were estimated for five metric traits using 24 biparental progenies (N. C. Design III) generated from F$_2$ generation of a commercial bivoltine silkworm hybrid, SH$_{6}$${\times}$NB$_4$D$_2$. Variance due to additive ($\sigma$$^2$A) and dominance ($\sigma$$^2$D) gene effects was significant for single cocoon weight and shell weight. However, magnitude of former was greater than latter indicating preponderance of additive gene action in the inheritance of these two traits. Average degree of dominance was in the range of partial dominance for all the traits. High estimates of heritability (ns) indicated operation of genes with large additive effects, hence, scope exists for improvement of present populations through a few cycles of selection.n.

Establishment of Ecological Preservation Zone on Uninhabited Island in Goseong-gun and Tongyeong-si, Korea (고성 및 통영 일대 무인도서의 생태보전권역 설정에 관한 연구)

  • KIM, Jang-soo;JANG, Dong-Ho
    • Journal of The Geomorphological Association of Korea
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    • v.20 no.4
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    • pp.71-83
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    • 2013
  • In this study, the ecological presevation zone on uninhabited islands was established based on the setting of geomorphological landscape. The 14 uninhabited islands, which are scattered around the Goseong-gun and Tongyeong-si region have been surveyed on field. As a result of study, uninhabited island of Goseong-gun and Tongyeong-si was classified the absolute preservation areas(I), preservation areas(II), quasi-preservation areas(III), and a available areas(IV). These results evaluated 5 islands of Anjang Island(Maan-do), Bam Island, Saetgaekkeut, Dae Island(Juk-do) and Ttandok Island to be absolute preservation areas(I), the 8 islands of Mana Island, Yuk Island, Nabi Island, Sochi Island, Yongdu-do, Daeho-do, Jam-do, and Hwa-do to be preservation areas(II), the 1 island of Goeam Island to be quasipreservation areas(III). Those islands selected as absolute preservation areas and preservation areas have especially outstanding geomorphological landscape resources, and are expected to be able for use as natural study fields or as outdoor laboratories.

Cryo-Compression Therapy After Elective Spinal Surgery for Pain Management: A Cross-Sectional Study With Historical Control

  • Nabiyev, Vugar Nabi;Ayhan, Selim;Adhikari, Prashant;Cetin, Engin;Palaoglu, Selcuk;Acaroglu, R. Emre
    • Neurospine
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    • v.15 no.4
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    • pp.348-352
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    • 2018
  • Objective: Postoperative dynamic cryo-compression (DC) therapy has been proposed as a method of reducing pain and the inflammatory response in the early postoperative period after orthopedic joint reconstruction surgery. Our aim was to analyze the analgesic efficacy of DC therapy after adult lumbar spinal surgery. Methods: DC was applied for 30 minutes every 6 hours after surgery. Pain was measured by a visual analogue scale (VAS) in the preoperative period, immediately after surgery, and every 6 hours postoperatively for the first 72 hours of the hospital stay. Patients' pain medication requirements were monitored using the patient-controlled analgesia system and patient charts. Twenty patients who received DC therapy were compared to 20 historical controls who were matched for demographic and surgical variables. Results: In the postanesthesia care unit, the mean VAS back pain score was $5.87{\pm}0.9$ in the DC group and $6.95{\pm}1.0$ (p=0.001) in the control group. The corresponding mean VAS scores for the DC vs. control groups were $3.8{\pm}1.1$ vs. $5.4{\pm}0.7$ (p < 0.001) at 6 hours postoperatively, and $2.7{\pm}0.7$ vs. $6.25{\pm}0.9$ (p<0.001) at discharge, respectively. The cumulative mean analgesic consumption of paracetamol, tenoxicam, and tramadol in the DC group vs. control group was $3,733.3{\pm}562.7mg$ vs. $4,633.3{\pm}693.5mg$ (p<0.005), $53.3{\pm}19.5mg$ vs. $85.3{\pm}33.4mg$ (p<0.005), and $63.3{\pm}83.4mg$ vs. $393.3{\pm}79.9mg$ (p<0.0001), respectively. Conclusion: The results of this study demonstrated a positive association between the use of DC therapy and accelerated improvement in patients during early rehabilitation after adult spine surgery compared to patients who were treated with painkillers only.

Probabilistic exposure assessment, a risk-based sampling plan and food safety performance evaluation of common vegetables (tomato and brinjal) in Bangladesh

  • Mazumder, Mohammad Nurun-Nabi;Bo, Aung Bo;Shin, Seung Chul;Jacxsens, Liesbeth;Akter, Tahmina;Bir, Md. Shahidul Haque;Aktar, Most Mohshina;Rahman, Md. Habibur;WeiQiang, Jia;Park, Kee Woong
    • Korean Journal of Agricultural Science
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    • v.48 no.1
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    • pp.33-43
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    • 2021
  • Along with the widespread use of pesticides in the world, concerns over human health impacts are rapidly growing. There is a large body of evidence on the relationship between the exposure to pesticides and the elevated rate of chronic diseases such as different types of cancers, diabetes, neurodegenerative disorders like Parkinson, Alzheimer, and amyotrophic lateral sclerosis (ALS), birth defects, and reproductive disorders. This research assessed the health risk of pesticide residues by the dietary intake of vegetables collected from the agro-based markets of Dhaka, Bangladesh. As some of the banned pesticides were also found in vegetable samples, they may pose a higher risk because of cheaper availability and hence the government of Bangladesh should take strong measures to control these banned pesticides. Five organo phosphorus (chlorpyrifos, parathion, ethion, acephate, fenthion) and two carbamate (carbaryl and carbofuran) pesticide residues were identified in twenty four samples of two common vegetables (tomato and brinjal). The pesticide residues ranged from below a detectable limit (< 0.01) to 0.36 mg·kg-1. Acephate, chlorpyrifos, ethion, and carbaryl were detected in only one sample, while co-occurrence occurred twice for parathion. Continuous monitoring and strict regulation should be enforced regarding the control of pesticide residues in fresh vegetables and other food commodities in Bangladesh.