• Title/Summary/Keyword: N.$D_L$

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Whitening Effect of Dayflower (Commelina communis L.) Extract by Inhibition of N-Linked Glycosylation Process and Melanogenesis (N-Linked Glycosylation 저해에 의한 닭의장풀 추출물의 미백효능)

  • Park, Sun-Hee;Lee, Bang-Yong;Lee, Seung-Hyun;Han, Chang-Sung;Kim, Jin-Guk;Kim, Kyoung-Tae;Kim, Ki-Ho;Kim, Young-Heui
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.35 no.1
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    • pp.73-78
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    • 2009
  • In order to investigate the potential of a Dayflower (Commelina communis L.) extract as an active in gredient for whitening cosmetics, we prepared aqueous Commelina communis L. extract We measured its mushroom tyrosinase inhibitory activity, cellular tyrosinase activity, and melanin synthesis inhibitory activity in B16 melanoma cells. It did not show inhibitory activity against mushroom tyrosinase but showed melanin synthesis inhibitory activity. In a melanin synthesis inhibition assay using mouse B16-F10 melanoma cell, it suppressed melanin production up to 32% at a concentration of $1,000{\mu}/mL$ without cytotoxicity, and also reduced cellular tyrosinase activity to above 50 % above the concentration of $250{\mu}g/mL$. In study on the melanogenic protein expressions, it had especially influence on expression of tyrosinase protein, which is a well-known key protein on melanogenesis, and tyrosinase expression was gradually decreased in a dose-dependent. Dayflower also blocked N-glycosylation of TRP-2, but affected on the expression of TRP-1 rather than on blocking of N-glycosylation processing. Therefore, this result suggests that aqueous Commelina communis L. extract could be used as an active ingredient for whitening cosmetics.

THE RELATION PROPERTY BETWEEN THE DIVISOR FUNCTION AND INFINITE PRODUCT SUMS

  • Kim, Aeran
    • Honam Mathematical Journal
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    • v.38 no.3
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    • pp.507-552
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    • 2016
  • For a complex number q and a divisor function ${\sigma}_1(n)$ we define $$C(q):=q{\prod_{n=1}^{\infty}}(1-q^n)^{16}(1-q^{2n})^4,\\D(q):=q^2{\prod_{n=1}^{\infty}}(1-q^n)^8(1-q^{2n})^4(1-q^{4n})^8,\\L(q):=1-24{\sum_{n=1}^{\infty}}{\sigma}_1(n)q^n$$ moreover we obtain the number of representations of $n{\in}{\mathbb{N}}$ as sum of 24 squares, which are possible for us to deduce $L(q^4)C(q)$ and $L(q^4)D(q)$.

Dietary Effect of Liriopis Tuber Water Extracts on the Level of Blood Glucose and Serum Cholesterol in Streptozotocin-Induced Diabetic Rat (맥문동 물 추출물의 식이가 Streptozotocin으로 유도한 당뇨 흰쥐의 혈당과 혈청 콜레스테롤 함량에 미치는 영향)

  • Im Jung-Gyo;Kang Myung-Su;Park In-Kyung;Kim Soon-Dong
    • Journal of the East Asian Society of Dietary Life
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    • v.15 no.1
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    • pp.20-28
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    • 2005
  • The dietary effect of water extracts of Liriopis tuber(WELT) in the diabetic SD-rats on the level of blood sugar and serum cholesterol was investigated. The experimental plots divided into normal group(N), diabetic control(DC), 5% WELT-group(WELT-I) and 10% WELT-group (WELT-II). Each group was fed for 6 weeks, then continuously fed for 1 more week after streptozotocin injection. The loss of the body weight fed for one week after induction of the diabetes was 2.2~6.3% in the WELT-I and -II groups, but it was 18.6% in the DC-group. There was no significant difference in the feed intakes after diabetes induction between N-group and WELT-group, while it was significantly increased in DC-group. The feed efficiency ratios before diabetes induction were 1.70 in WELT-I group, 1.53~1.59 in the N, DC and WELT-II group, while the ratios after diabetes induction were 0.92 in DC-group, 1.51~1.83 in the N, WELT-I and -II group. While the amounts of water intakes for one week after diabetes induction was 625.4 mL in the DC-group, and it were 364.3~371.1 mL in the WELT-groups showing no significant difference with N-group. The excretion amounts of urine were 431.96 mL in DC-group for one week after diabetes induction, and it was 182~192.84 mL in WELT-groups. The ratios of liver weight against body weight were 2.74% in N-group, 2.93~2.96% in WELT-groups, but it was 4.01% in DC-group. The level of blood glucose in WELT-groups fed for one week after diabetes induction were 136.8~138.6 mg/dL showing no significant difference with N-group, but it was 357.8 mg/dL in DC-group. The level of serum triacylglycerol and serum total cholesterol were 93.8 and 68.7 mg/dL in N-group, 120.1 and 101.6 mg/dL in DC-group, 97.4~100.6 and 60.8~67.7 mg/dL in WELT-groups, respectively, showing no significant difference between N-group and WELT-groups. HDL-cholesterol/total cholesterol ratio were 0.63 in N-group, 0.57~0.67 in WELT -groups, which was significantly higher than that of DC-group(p<0.05). Atherogenic index were 0.58 in N-group, 0.49~0.74 in WELT-groups, but it was 1.32 in DC-group. The above results suggest that the WELT diets may have both preventive and curing effects against the diabetes.

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Ammonia Effects on Anaerobic Digestion of Swine Wastewaters (양돈폐수의 혐기성 소화에 대한 암모니아의 영향)

  • Kim, Jong-Soo
    • Journal of the Korea Organic Resources Recycling Association
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    • v.10 no.1
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    • pp.102-108
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    • 2002
  • The effects of ammonia on mesophilic anaerobic digestion were investigated by operating lab-scale two-stage ASBF reactors using swine wastewaters as influent without and with ammonia removal at HRT of 1-2 days and OLR of $2.2{\sim}9.6kg-COD/m^3{\cdot}d$ for 250 days. The COD removal efficiency and biogas generation of two-stage ASBF reactors was decreased by increasing influent ammonia concentrations to 1,580 mg(T-N)/L with increasing OLR to $6.3kg-COD/m^3{\cdot}d$, while those were increased by maintaining influent ammonia concentrations below 340 mg(T-N)/L by MAP precipitation with increasing OLR to $9.6kg-COD/m^3{\cdot}d$. Initial inhibirion of ammonia on anaerobic processes was observed at a concentration of 760 mg(T-N)/L and the COD removal efficiency and biogas generation dropped to 1/2 at ammonia concentration ranges of 1,540~1,870 mg(T-N)/L. It is essential to remove ammonia in swine wastewaters to an initial inhibition level before anaerobic processes for the effective removal of COD.

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Influence of 3-(N-methyl-N-X(Sub.)Phenylaminooxoacetyl) Group on the Herbicidal Activity of Imazapyr Derivatives (Imazapyr 유도체의 제초활성에 미치는 3-(N-methyl-N(X)-치환-Phenylaminooxoacetyl) Group의 영향)

  • Sung, N.D.;Ryu, T.S.;Chang, H.S.;Kim, D.W.
    • Applied Biological Chemistry
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    • v.37 no.6
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    • pp.516-521
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    • 1994
  • New seventeen imazapyr derivatives, 2-(4-isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl)-3-(N-methyl-N-X(sub.)-phenylaminooxoacetyl)pyridine, 6 were synthesized and their pre-emergence herbicidal activity$(pI_{50})$ in vivo against Corn (Zea mays L.) and Pigweed (Amaranthus viridis L.) were studied by the pot test under paddly conditions. Quantitative structure activity relationships (QSARs) were analyzed using the physicochemical parameters of substituent(X) on the phenyl ring of 3-(N-methyl-N-X(sub.)-phenylaminooxoacetyl) group and regression analysis. The herbicidal activities were related to the steric effect of X-substituent. The effect was rationalized by paraholic function of MR and $L_1$, where the optimal values were MR=5.56 (Zea mays L.) and $L_1=3.34\;{{\AA}}$ (Amaranthus viridis L.). Among them, 2,5-difluoro substituted compound, 6i showed good herbicidal activity against Pigweed with excellent tolerance to Corn.

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A NOTE ON SKEW DERIVATIONS IN PRIME RINGS

  • De Filippis, Vincenzo;Fosner, Ajda
    • Bulletin of the Korean Mathematical Society
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    • v.49 no.4
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    • pp.885-898
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    • 2012
  • Let m, n, r be nonzero fixed positive integers, R a 2-torsion free prime ring, Q its right Martindale quotient ring, and L a non-central Lie ideal of R. Let D : $R{\rightarrow}R$ be a skew derivation of R and $E(x)=D(x^{m+n+r})-D(x^m)x^{n+r}-x^mD(x^n)x^r-x^{m+n}D(x^r)$. We prove that if $E(x)=0$ for all $x{\in}L$, then D is a usual derivation of R or R satisfies $s_4(x_1,{\ldots},x_4)$, the standard identity of degree 4.

REMARKS ON NONSPECIAL LINE BUNDLES ON GENERAL κ-GONAL CURVES

  • CHOI, YOUNGOOK;KIM, SEONJA
    • Journal of the Korean Mathematical Society
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    • v.52 no.5
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    • pp.991-1001
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    • 2015
  • In this work we obtain conditions for nonspecial line bundles on general ${\kappa}$-gonal curves failing to be normally generated. Let L be a nonspecial very ample line bundle on a general ${\kappa}$-gonal curve X with ${\kappa}{\geq}4$ and $deg\mathcal{L}{\geq}{\frac{3}{2}}g+{\frac{g-2}{{\kappa}}}+1$. If L fails to be normally generated, then L is isomorphic to $\mathcal{K}_X-(ng^1_{\kappa}+B)+R$ for some $n{\geq}1$, B and R satisfying (1) $h^0(R)=h^0(B)=1$, (2) $n+3{\leq}degR{\leq}2n+2$, (3) $deg(R{\cap}F){\leq}1$ for any $F{\in}g^1_k $. Its converse also holds under some additional restrictions. As a corollary, a very ample line bundle $\mathcal{L}{\simeq}\mathcal{K}_X-g^0_d+{\xi}^0_e$ is normally generated if $g^0_d{\in}X^{(d)}$ and ${\xi}^0_e{\in}X^{(e)}$ satisfy $d{\leq}{\frac{g}{2}}-{\frac{g-2}{\kappa}}-3$, supp$(g^0_d{\cap}{\xi}^0_e)={\phi}$ and deg$(g^0_d{\cap}F){\leq}{\kappa}-2$ for any $F{\in}g^1_k$.

Enantiomeric Separation of Free Amino Acids Using N-alkyl-L-proline Copper(Ⅱ) Complex as Chiral Mobile Phase Additive in Reversed Phase Liquid Chromatography

  • Lee Sun Haing;Oh Tae Sub;Lee Hae Woon
    • Bulletin of the Korean Chemical Society
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    • v.13 no.3
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    • pp.280-285
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    • 1992
  • Enantiomeric separation of free amino acids has been achieved by a reversed phase liquid chromatography with addition of a Cu(Ⅱ) complex of N-alkyl-L-proline (alkyl: propyl, pentyl or octyl) to the mobile phase. The amino acids eluted were detected by a postcolumn OPA system. N-alkyl-L-proline was prepared and used as a chiral ligand of Cu(Ⅱ) chelate for the enantiomeric separation. The concentration of the Cu(Ⅱ) chelate, the organic modifier and pH affect the enantiomeric separation of free amino acids. The retention behaviour, varied with change in pH and the concentration of the Cu(Ⅱ) chelate, was different compared with those of the derivatized amino acids. The elution orders between D- and L-forms were consistent except histidine showing that L-forms elute earlier than D-forms. The retention mechanism for the enantiomeric separation can be illustrated by the stereospecificity of the ligand exchange reaction and the hydrophobic interaction between the substituent of amino acids and reversed phase, $C_18$.

The analysis of electron transport coefficients in Xenon gas by multi-term approximation of the Boltzmann equation (볼츠만 다항근사 방정식을 이용한 Xe 가스의 전자수송계수 해석)

  • Jeon, Byoung-Hoon;Ha, Sung-Chul;Song, Byoung-Doo
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2003.05e
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    • pp.73-76
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    • 2003
  • This paper describes the information for quantitative simulation of weakly ionized plasma. In previous paper, we calculated the electron transport coefficients in pure Xenon gas by using two-term approximation of Boltzmann equation. Therefore, in this paper, we calculated the electron transport coefficients(W, $N{\cdot}D_L$ and $D_{L/{\mu}}$) in pure Xenon gas for range of E/N values from 0.01 ~ 500[Td] at the temperature was 300[K] and pressure was 1[Torr] by using multi-term approximation of the Boltzmann equation by Robson and Ness, The results of two-term and multi-term approximation of the Boltzmann equation has been compared with the experimental data by L. S. Frost and A. V. Phelps for a range of E/N.

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A Lattice Distribution

  • Chung, Han-Young
    • Journal of the Korean Statistical Society
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    • v.10
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    • pp.97-104
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    • 1981
  • It is shown that a lattice distribution defined on a set of n lattice points $L(n,\delta) = {\delta,\delta+1,...,\delta+n-1}$ is a distribution induced from the distribution of convolution of independently and identically distributed (i.i.d.) uniform [0,1] random variables. Also the m-th moment of the lattice distribution is obtained in a quite different approach from Park and Chung (1978). It is verified that the distribution of the sum of n i.i.d. uniform [0,1] random variables is completely determined by the lattice distribution on $L(n,\delta)$ and the uniform distribution on [0,1]. The factorial mement generating function, factorial moments, and moments are also obtained.

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