• Title/Summary/Keyword: N loss

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The Comparison of the Effects of Nicardipine and Remifentanil on Fluctuation of Blood Pressure during Controlled Hypotension (유도 저혈압하 양악 교정술 시 Nicardipine과 Remifentanil의 혈역학적 비교)

  • Kim, Eun-Soo;Hwang, Boo-Young;Kim, Cheul-Hong
    • Journal of The Korean Dental Society of Anesthesiology
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    • v.10 no.2
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    • pp.166-171
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    • 2010
  • Background: Controlled hypotension is used to reduce bleeding and improve surgical conditions during surgery. Nicardipine and remifentanil have been used to induce controlled hypotension in healthy patients. This study compared controllability of nicardipine and remifentanil on hemodynamic stability during controlled hypotension. Methods: Forty healthy patients scheduled for orthognathic two jaw surgery were randomly allocated to nicardipine (group N) and remifentanil (group R) group. After induction of anesthesia, group N (n = 20) was infused with nicardipine to induce hypotension and group R (n = 20) was infused with remifentanil. Mean arterial pressure (MAP) and heart rate (HR) were measured over 5 minute interval. Surgical field rating and blood loss were measured after surgery. Results: HR was lower in group R than group N. MAP was maintained at 50-60 mmHg during controlled hypotension but the fluctuation of blood pressure and HR were more frequent in group N than group R. There were no significant differences in the surgical field rating and blood loss between the groups. Conclusions: Nicardipine and remifentanil enabled controlled hypotension and provided good surgical conditions, but the fluctuation of hemodynamic parameters was more frequent in nicardipine group.

Chemical Modification of Porcine Brain myo-Inositol Monophosphate Phosphatase by N-bromosuccinimide

  • Lee, Byung-Ryong;Bahn, Jae-Hoon;Jeon, Seong-Gyu;Ahn, Yoon-Kyung;Yoon, Byung-Hak;Kwon, Hyeok-Yil;Kwon, Oh-Shin;Choi, Soo-Young
    • BMB Reports
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    • v.32 no.3
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    • pp.294-298
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    • 1999
  • Myo-inositol monophosphate phosphatase is a key enzyme in the phosphoinositide cell-signaling system. Incubation of myo-inositol monophosphate phosphatase from porcine brain with N-bromosuccinimide (NBS) resulted in a time-dependent loss of enzyme activity. The inactivation followed pseudo-first-order kinetics with the second-order rate constant of $3.8{\times}10^3\;M^{-1}min^{-1}$. The time course of the reaction was significantly affected by the substrate myo-inositol-1-phosphate, which afforded complete protection against the loss of catalytic activity. Spectrophotometric studies indicated that about one oxindole group per molecule of enzyme was formed following complete loss of enzymatic activity. It is suggested that the catalytic function of myo-inositol monophosphate phosphatase is modulated by the binding of NBS to a specific tryptophan residue at or near the substrate binding site of the enzyme.

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Retrospective Clinical Study on Marginal Bone Loss of Implants with Guided Bone Regeneration (골유도재생술과 동시에 식립한 임플란트의 변연골 흡수량에 대한 후향적 고찰)

  • Park, Seul-Ji;Seon, Hwa-Gyeong;Koh, Se-Wook;Chee, Young-Deok
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.34 no.6
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    • pp.440-448
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    • 2012
  • Purpose: The purpose of this study was to evaluate marginal bone loss of the alveolar crest on implants with or without guided bone regeneration and variables that have influenced. Methods: The clinical evaluation were performed for survival rate and marginal bone loss of 161 endosseous implants installed with guided bone regeneration (GBR) in 83 patients from September 2009 to October 2010 in relation to sex and age of patients, position of implant, implant system, length and diameter of implant. Study group (n=42) implant with GBR procedure, control group (n=41) implant without GBR technique. Simultaneous GBR approach using resorbable membranes combined with autogenous bone graft or freeze-dried bone allograft or combination. Radiographic examinations were conducted at healing abutment connection and latest visit. Marginal bone level was measured. Results: Mean marginal bone loss was 0.73 mm in study group, 0.63 mm in control group. Implants in maxillary anterior area (1.21 mm) were statistically significant in study group (P<0.05), maxillary posterior area (0.81 mm) in control group (P<0.05). Mean marginal bone loss 1.47 mm for implants with diameter 3.4 mm, 0.83 mm for implants of control group with diameter 4.0 mm (P<0.05). Some graft materials showed an increased marginal bone loss but no statistically significant influence of sex, implant type or length. Conclusion: According to these findings, this study demonstrated the amount of marginal bone loss around implant has maintained a relative stable during follow-up periods. We conclude that implants with GBR had similar survival rate and crestal bone level compared with implants in native bone.

Analysis of Factors Influencing Obesity Treatment according to Initial Condition and Compliance with Medication (초기 조건과 복약 순응도에 따른 비만 치료 영향 인자 분석)

  • Han, Ji-Yeon;Park, Young-Jae
    • Journal of Korean Medicine for Obesity Research
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    • v.19 no.1
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    • pp.31-41
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    • 2019
  • Objectives: The purpose of this study was to investigate the effects of gender, age, body weight, muscle mass, fat mass, body mass index (BMI), metabolism, and compliance with medication on weight loss in obese adults. Methods: We reviewed the medical records of 178 patients who were visited to the Korean Oriental Clinic for 3~6 month and had obesity treatment using Gamitaeumjowee-tang from April 2017 to May 2017. We conducted a paired T-test, correlation coefficient and decision tree to analyze factors influencing obesity treatment. Results: The results of correlation analysis showed that initial weight (kg), initial fat mass (kg), BMI ($kg/m^2$), compliance with medication (%), Original Harris-Benedict Equation, Revised Harris-Benedict Equation and The Mifflin St Jeor Equation was significantly correlated to weight loss (kg) (P<0.001). As a result of constructing the decision tree model, it showed that over 5% weight loss of their initial weight (n=154) was related with initial BMI ($kg/m^2$), compliance with medication (%) and initial muscle mass (kg). In case of over 5 kg weight loss of their initial weight (n=131), it was related with initial BMI ($kg/m^2$), compliance with medication (%) and final BMI ($kg/m^2$). Conclusions: This study suggests that weight loss may be affected by initial factors and that initial factors can be used for obesity treatment.

Gamitaeeumjowee-Tang for weight loss in diabetic patients: A retrospective chart review (당뇨 환자의 체중감량을 위한 가미태음조위탕의 임상적 활용: 후향적 차트 리뷰)

  • Lee, A-Reum;Lee, Da-Yeon;Kim, Min-Ji;Lee, Hyang-Sook;Choi, Ka-Hye;Kim, Seo-Young;Lim, Young-Woo;Park, Young-Bae
    • The Journal of Korean Medicine
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    • v.42 no.1
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    • pp.46-58
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    • 2021
  • Objectives: The purpose of this study is to report weight changes and analyze adverse events in diabetic patients with Gamitaeeumjowee-Tang for weight loss. Methods: A retrospective chart review of weight change and adverse events was performed during the 10-week weight loss program using Gamitaeeumjowee-tang with low-calorie diets for diabetics(n=61). Weight and BMI changes were compared before and after the program and calculated the percentage of people who lost more than 5% of their weight, also identified whether subjects felt satiated or not. Adverse events were evaluated in terms of causality, severity and system-organ classes. Results: After 10-week weight loss program, significant weight loss (5.9±2.32kg, 7.73% reduction from baseline) and BMI reduction (2.9±0.86) were reported (n=61). Those who lost more than 5 percent of their body weight accounted for 88.5%, and also 88.5% of the participants felt full to help control their appetite. In assessing the causality of adverse events, 'Unlikely' was the most common (66%) and in severity evaluations, almost all symptoms were mild. Insomnia was the most frequently reported during the first 8 weeks, and constipation was reported the most afterwards. Conclusions: A combination of Gamitaeeumjowee-tang and low-calorie diets for 10 weeks appears to help weight reduction without serious adverse events in diabetic patients. Future well-designed prospective clinical studies testing the effectiveness and safety of this weight loss program are warranted.

Effect of a 3C-SiC buffer layer on SAW properties of AlN films (3C-SiC 버퍼층이 AlN 박막형 SAW 특성에 미치는 영향)

  • Hoang, Si-Hong;Chung, Gwiy-Sang
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2009.06a
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    • pp.235-235
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    • 2009
  • This paper describes the influence of a polycrystalline (poly) 3C-SiC buffer layer on the surface acoustic wave (SAW) properties of poly aluminum nitride (AlN) thin films by comparing the center frequency, insertion loss, the electromechanical coupling coefficient ($k^2$), andthetemperaturecoefficientoffrequency(TCF) of an IDT/AlN/3C-SiC structure with those of an IDT/AlN/Si structure, The poly-AlN thin films with an (0002)-preferred orientation were deposited on a silicon (Si) substrate using a pulsed reactive magnetron sputtering system. Results show that the insertion loss (21.92 dB) and TCF (-18 ppm/$^{\circ}C$) of the IDT/AlN/3C-SiC structure were improved by a closely matched coefficient of thermal expansion (CTE) and small lattice mismatch (1 %) between the AlN and 3C-SiC. However, a drawback is that the $k^2(0.79%)$ and SAW velocity(5020m/s) of the AlN/3C-SiC SAW device were reduced by appearing in some non-(0002)AlN planes such as the (10 $\bar{1}$ 2) and (10 $\bar{1}$ 3) AlN planes in the AlN/SiC film. Although disadvantages were shown to exist, the use of the AlN/3C-SiC structure for SAW applications at high temperatures is possible. The characteristics of the AlN thin films were also evaluated using FT-IR spectra, XRD, and AFM images.

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Path Loss Characteristics in Subway Platform at 2.45GHz Band (2.45GHz 대역의 지하철 플랫폼에서 경로손실 특성)

  • 최낙일;공민한;강영진;송문규
    • Proceedings of the IEEK Conference
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    • 2003.07a
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    • pp.318-321
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    • 2003
  • In this paper, path loss and delay profile characteristics are measured in the subway platform. To evaluate the fading characteristics of the measured signals, the standard deviations are computed. The standard deviation is bigger for shorter distance. The shorter the distance, the bigger the phase difference between direct wave and reflected waves according the distance, which results in heavy fading. To compute the path loss according to distance, the average values of path loss exponent(n) is evaluated. The path loss exponents measured in the subway environment for Omni-VP(omni-directional vertical polarization) antenna and CP(circular polarization) antenna are 1.418 and 1.680, respectively, which are considerably less than 2.0, the free space path loss exponent.

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A study on the Measurement of Field Transmission Loss through Doors in Buildings Using the Surface Intensity Method. (Surface Intensity 법에 의한 건물내 출입문의 차음성능 현장측정에 관한 연구)

  • Son, Jang Yeol;O, Jae Eung;Kim, Heung Sik
    • The Journal of the Acoustical Society of Korea
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    • v.4 no.2
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    • pp.3.1-3.1
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    • 1985
  • The surface intensity method is a relatively new tool which can identify the noise source or path and measure the radiation power. One microphone and one accelerometer are used in this new technique. In this study, this new technique has been used to measure the field transmission loss trough doors. The results of the experiment indicate that the surface intensity method produces reliable data and can be applied to the transmission loss measurement.

Performance Analysis of a Loss Retrial BMAP/PH/N System

  • Kim Che-Soong;Oh Young-Jin
    • Journal of Korea Society of Industrial Information Systems
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    • v.9 no.3
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    • pp.32-37
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    • 2004
  • This paper investigates the mathematical model of multi-server retrial queueing system with the Batch Markovian Arrival Process (BMAP), the Phase type (PH) service distribution and the finite buffer. The sufficient condition for the steady state distribution existence and the algorithm for calculating this distribution are presented. Finally, a formula to solve loss probability in the case of complete admission discipline is derived.

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A study on the Time Series Prediction Using the Support Vector Machine (보조벡터 머신을 이용한 시계열 예측에 관한 연구)

  • 강환일;정요원;송영기
    • 제어로봇시스템학회:학술대회논문집
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    • 2000.10a
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    • pp.315-315
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    • 2000
  • In this paper, we perform the time series prediction using the SVM(Support Vector Machine). We make use of two different loss functions and two different kernel functions; i) Quadratic and $\varepsilon$-insensitive loss function are used; ii) GRBF(Gaussian Radial Basis Function) and ERBF(Exponential Radial Basis Function) are used. Mackey-Glass time series are used for prediction. For both cases, we compare the results by the SVM to those by ANN(Artificial Neural Network) and show the better performance by SVM than that by ANN.