• Title/Summary/Keyword: Morphologic characteristics

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MRI-guided Wire Localization Open Biopsy is Safe and Effective for Suspicious Cancer on Breast MRI

  • Wang, Hai-Yi;Zhao, Yu-Nian;Wu, Jian-Zhong;Wang, Zheng;Tang, Jing-Hai
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.5
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    • pp.1715-1718
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    • 2015
  • Background: Magnetic resonance imaging of breast, reported to be a high sensitivity of 94% to 100%, is the most sensitive method for detection of breast cancer. The purpose of this study was to investigate our clinical experience in MRI-guided breast lesion wire localization in Chinese women. Materials and Methods: A total of 44 patients with 46 lesions undergoing MRI-guided breast lesion localization were prospectively entered into this study between November 2013 and September 2014. Samples were collected using a 1.5-T magnet with a special MR biopsy positioning frame device. We evaluated clinical lesion characteristics on pre-biopsy MRI, pathologic results, and dynamic curve type baseline analysis. Results: Of the total of 46 wire localization excision biopsied lesions carried out in 44 female patients, pathology revealed fourteen malignancies (14/46, 30.4%) and thirty-two benign lesions (32/46, 69.6%). All lesions were successfully localized followed by excision biopsy and assessed for morphologic features highly suggestive of malignancy according to the American College of Radiology Breast Imaging Reporting and Data System (BI-RADS) category of MRI (C4a=18, C4b=17, C4c=8,C5=3). Of 46 lesions, 37 were masses and 9 were non-mass enhancement lesions. Thirty-two lesions showed a continuous kinetics curve, 11 were plateau and 3 were washout. Conclusions: Our study showed success in MRI-guided breast lesion wire localization with a satisfactory cancer diagnosis rate of 30.4%. MRI-guided wire localization breast lesion open biopsy is a safe and effective tool for the workup of suspicious lesions seen on breast MRI alone without major complications. This may contribute to increasing the diagnosis rate of early breast cancer and improve the prognosis in Chinese women.

A CEPHALOMETRIC STUDY OF CRANIOFACIAL SKELETAL CHARACTERISTIC OF KOREAN ADOLESCENCES WITH NORMAL OCCLUSION (청소년기 정상교합자의 두개안면골격의 특성에 관한 연구)

  • Lee, Jeong-Min;Chung, Kyu-Rhim
    • The korean journal of orthodontics
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    • v.19 no.1 s.27
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    • pp.187-200
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    • 1989
  • The purpose of this study was to find out the craniofacial skeletal characteristics and to establish standards in facial patterns of Korean adolescences with normal occlusion. The subjects consisted of 54 males and 71 females ranging in age from 12 to 16 years. To classify facial patrons, number the clinical deviations from the normal five key measurements: the facial axis, facial angle, mandibular plane angle, lower face height, mandibular arc, are added and averaged with the proper sign to divide subjects into three groups ; brachyfacial, mesofacial dolichofacial groups. For the comparison of each group, a total of 43 morphologic variables were employed and the data were analyzed by statistical methods. The findings of this study can be summerized as follows; 1. The mesofacial group was $54.4\%$, the brachyfacial group was $29.6\%$ and the dolichofacial group was $16.0\%$ in this subjects. 2. There were no significant differences in size and shape of cranial base among each groups. 3. The brachyfacial group manifested the forward positioned maxilla and mandible to anterior cranial base, smaller cant of the mandibular plane, square shaped mandible, and prominent symphysis as compared with dolichofacial group. 4. There were no significant differences in the cant of the maxilla to the anterior cranial base among each groups. 5. Ramal height and madibular body length of brachyfacial group were larger than those of dolichofacial group. 6. Brachyfacial group indicated the smallest degree in divergency of maxilla and mandible while dolichofacial group showed the largest degree.

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Geomorphology and Geology of Mt. Deok on Bigeum Island, Shinan, Korea (신안 비금도 덕산의 지형 및 지질)

  • Chung, Chull-Hwan;Kim, Cheong-Bin
    • Journal of the Korean earth science society
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    • v.38 no.7
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    • pp.552-560
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    • 2017
  • This study investigates the development process of Mt. Deok on Bigeum Island, Shinan, on the basis of geomorphological and geological analyses. K-Ar dating was carried out on two samples of the acidic lapilli tuff developed in the study area, and the obtained K-Ar ages are $70.4{\pm}1.4$ and $76.9{\pm}1.5Ma$, which correspond to the Late Cretaceous (Campanian). Mt. Deok is surrounded by rock cliff, and various weathering microtopographic features, such as tafoni, tor and gnamma, are developed. Tafoni with diverse morphologic types is the most dominant feature, indicative of intense salt weathering. Geological characteristics such as porous tuff and joint have played an important role in the development of tafoni and rock cliff. Geomorphology and geology of Mt. Deok reflect paleoenvironmental change and interaction between human and nature in the coastal area.

Inhibitory Effect of Retinoic Acid on lipid Synthesis in Human Sebocyte (피지선세포에서 Retinoic Acid의 피지생성억제효과)

  • Mun Yeun Ja;Kim Youn Seok;Kwon Gang Joo;Rhee Hee Sub;Roh Seong Taek;Kim Yang Jin;Lee Jang Cheon;Woo Won Hong
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.18 no.5
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    • pp.1317-1321
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    • 2004
  • The differentiation of the sebaceous gland is remarkably species-specific and sebocytes may play crucial parts in the pathophysiologic processes and disorders of pilosebaceous unit SZ95 cell is an immortalized human sebaceous gland cell line that shows characteristics of normal human sebocytes, In this study, we investigated the effect of testosterone and the anti-androgenic effect of 13-cis-retinoic acid (13-cis-RA) on lipid synthesis in SZ95 cells. Cytoplasmic lipid droplets were shown by Oil-red staining. The majority of the SZ95 cells positively labeled with Oil-red dye, while HaCaT cells negatively labeled with Oil red dye. Total lipid level of SZ96 cells is higher 4 times than that of HaCat cells. Testosterone markedly increased 2 times lipid synthesis of SZ95 cells in compared with control. 13-cis-RA significantly inhibited lipid synthesis and cell proliferation in SZ95 cells. Combined treatment with testosterone and 13-cis-RA resulted in a lower total lipid levels than that with androgen alone. In conclusion, SZ95 cells well resembled the morphologic and functional characteritics of normal human sebocytes. This in vitro model could provide a valuable tool for the study of sebocytes with a key role in pathophysiology and differentiation of sebaceous glands.

First Blindness Cases of Horses Infected with Setaria Digitata (Nematoda: Filarioidea) in the Republic of Korea

  • Shin, Jihun;Ahn, Kyu-Sung;Suh, Guk-Hyun;Kim, Ha-Jung;Jeong, Hak-Sub;Kim, Byung-Su;Choi, Eunsang;Shin, Sung-Shik
    • Parasites, Hosts and Diseases
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    • v.55 no.6
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    • pp.667-671
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    • 2017
  • Ocular setariases of cattle were reported but those of equine hosts have never been reported in the Republic of Korea (Korea). We found motile worms in the aqueous humor of 15 horses (Equus spp.) from 12 localities in southern parts of Korea between January 2004 and November 2017. After the affected animals were properly restrained under sedation and local anesthesia, 10 ml disposable syringe with a 16-gauge needle was inserted into the anterior chamber of the affected eye to successfully remove the parasites. The male worm that was found in 7 of the cases showed a pair of lateral appendages near the posterior terminal end of the body. The papillar arrangement was 3 pairs of precloacal, a pair of adcloacal, and 3 pairs of postcloacal papillae, plus a central papilla just in front of the cloaca. The female worms found in the eyes of 8 horses were characterized by the tapering posterior terminal end of the body with a smooth knob. Worms were all identified as Setaria digitata (von Linstow, 1906) by the morphologic characteristics using light and electron microscopic observations. This is the first blindness cases of 15 horses infected with S. digitata (Nematoda: Filarioidea) in Korea.

Morphometric Relationship between the Cervicothoracic Cord Segments and Vertebral Bodies

  • Kim, Ji Hoon;Lee, Chul Woo;Chun, Kwon Soo;Shin, Won Han;Bae, Hack-Gun;Chang, Jae Chil
    • Journal of Korean Neurosurgical Society
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    • v.52 no.4
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    • pp.384-390
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    • 2012
  • Objective : The objective of this study was to investigate the morphologic characteristics between the vertebral body and the regions of the cervical and thoracic spinal cords where each rootlets branch out. Methods : Sixteen adult cadavers (12 males and 4 females) with a mean age of 57.9 (range of 33 to 70 years old) were used in this study. The anatomical relationship between the exit points of the nerve roots from the posterior root entry zone at each spinal cord segment and their corresponding relevant vertebral bodies were also analyzed. Results : Vertical span of the posterior root entry zone between the upper and lower rootlet originating from each spinal segment ranged from 10-12 mm. The lengths of the rootlets from their point of origin at the spinal cord to their entrance into the intervertebral foramen were 5.9 mm at the third cervical nerve root and increased to 14.5 mm at the eighth cervical nerve root. At the lower segments of the nerve roots (T3 to T12), the posterior root entry zone of the relevant nerve roots had a corresponding anatomical relationship with the vertebral body that is two segments above. The posterior root entry zones of the sixth (94%) and seventh (81%) cervical nerve roots were located at a vertebral body a segment above from relevant segment. Conclusion : Through these investigations, a more accurate diagnosis, the establishment of a better therapeutic plan, and a decrease in surgical complications can be expected when pathologic lesions occur in the spinal cord or vertebral body.

Acinetobacter antiviralis sp. nov., from Tobacco Plant Roots

  • Lee, Jung-Sook;Lee, Keun-Chul;Kim, Kwang-Kyu;Hwang, In-Cheon;Jang, Cheol;Kim, Nam-Gyu;Yeo, Woon-Hyung;Kim, Beom-Seok;Yu, Yong-Man;Ahn, Jong-Seog
    • Journal of Microbiology and Biotechnology
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    • v.19 no.3
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    • pp.250-256
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    • 2009
  • Acinetobacter strain $KNF2022^T$ was isolated from tobacco plant roots during the screening of antiviral substances having inhibitory effects on Tobacco mosaic virus (TMV) and examined by phenotypic, chemotaxonomic, and genetic characterization. It was a nonmotile, Gram-negative bacterium. This strain contained Q-9 as the main respiratory quinone. The major cellular fatty acids of the isolate were 16:0, 18:1 w9c, and 16:1 w7c/15 iso 2OH. The DNA base composition was 44 mol%. Phylogenetic analysis based on the 16S rRNA sequence revealed that the isolate formed an evolutionary lineage distinct from other Acinetobacter species. Based on the evaluation of morphologic, physiologic, and chemotaxonomic characteristics, DNA-DNA hybridization values, and 16S rRNA sequence comparison, we propose the new species Acinetobacter antiviralis sp. nov., the type strain of which is $KNF2022^T$ (=KCTC $0699BP^T$).

Depositional Landforms in Jiwoo Drainage Basin (지우천 유역의 퇴적지형 연구)

  • Oh, In-Sun
    • Journal of the Korean association of regional geographers
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    • v.15 no.2
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    • pp.192-203
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    • 2009
  • The purpose of this paper is to elucidate the formative processes of depositional landforms in Jiwoo drainage basin which located in the most upstream reach of Namgang River. Through the analysis of morphologic characteristics and sedimentary facies, the formative processes can be summarized as follow: First, the high depositional landforms(Sapyeong, Eungam, Naedongdyttle site) were formed by gelifluction process in the periglacial environment during the last glacial period. And the relative height over river bed of them is getting lower from upper to downstream. The extent of the high depositional landforms is assumed about 1 kilometer downstream far from the confluence of Jiwoo stream and Namgang River. Second, the sediments in the gentle slope at Jangseungbuldle were carried by gelifluction process during the last glacial stage after the deep-weathered bedrock had formed a gentle slope. Third, the high depositional landforms were dissected during warm and humid environment of postglacial stage, and some sediments of them were left in the river bed. Later, as the more upstream high depositional landforms were dissected completely, stream power was getting more than resistance(sediment storage) and the low depositional landforms(Sapyeong, Yongchusa, Deungbangdle site) were formed.

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A Study on Every Printed Books of Hanmunbon Great Learn (大學) in Chosun Dynasty (조선시대에 간행된 한문본 대학의 제판본에 관한 연구)

  • Song Il-Gie;Ahn Hyeonju
    • Journal of Korean Library and Information Science Society
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    • v.36 no.2
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    • pp.13-30
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    • 2005
  • This paper is a morphologic-bibliographic analysis on every printed books of Hanmunbon Great Learn(大學), one of $\lceil$FourBooks(四書)$\rfloor$, in Chosun Dynasty. Through examination of the physical characteristics of oks in many institutes and private collections, $\lceil$Daehakjanggudaejun(大學章句大全)$\rfloor$, was systematically explored, which was the most frequently Published Great Learn (大學) in Chosun Dynasty. The Hanmunbon Great Learn (大學) was published mainly in Central Publishing Office in Hansung Area and Kyungsang provinces, and in the period of 17C to 19C. There are two streams of $\lceil$Daehakjanggudaejun$\rfloor$. One is the reprinted edition of Myungbon(明本覆刻), originated from $\lceil$Saseookyungdaejun(四書五經大全)$\rfloor$, compiled by Hokwang(胡廣) and colleagues in Myung(明). The second is movable type books of Chosun(朝鮮活字本), the contents of which being the same as the other stream.

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Study on Characteristics of Maxillofacial Growth in Class III Malocclusion Patients by Cranial Base Growth (3급 부정교합 환자에서 두개저 성장 양상에 따른 악골 성장 특성에 관한 연구)

  • Son, Do-Kyoung;Park, Sung-Won;Lee, Jae-Min;Kim, Eun-Ja;Choi, Sang-Mun;Kim, Young-Woon;Choi, Mun-Gi;Oh, Sung-Hwan
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.33 no.6
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    • pp.483-489
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    • 2011
  • Purpose: Craniofacial structure form results from the adaptation to morphologic and functional changes in their neighboring structures for a mutual balance. The purpose of this study is classification of maxillomandibular complex growth pattern follow by cranial base growth pattern. And this study is identifying the correlation between maxilla-mandibular complex growth pattern and orthodontic criteria. Methods: 142 Class III malocclusion patients had orthognathic surgery at Wonkwang University Dental Hospital during April 2004 to October 2010. Patients were divided into 4 groups and the correlation between cranial base and maxillomandibular growth patterns were evaluated. Results: There was a correlation between cranial base and maxillomandibular growth patterns. Positive relationships were found between the occlusal plane, Incisor mandibular plane angle, mandibular plane, positioning of pogonion and the saddle angle, indicating maxillary growth patterns. Negative relationships were found between SNA, SNB, maxillary incisor angle and saddle angle. Positive relationships were found between the ratio of the anterior and posterior cranium, positioning of pogonion and the percentage of cranial depth indicating mandibular growth patterns. Negative relationships were found between the occlusal plane, maxillary incisor angle, mandibular plane, mandibular angle and cranial depth. Conclusion: Cranial base and maxillofacial growth patterns were correlated and the classification should be adjusted before orthognathic surgery.