• Journal of Korean Society of Rural Planning
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• v.11 no.3 s.28
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• pp.59-67
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• 2005

According to diverse studies in population migration, there has been a strong age-dependent population distribution in Korea. It is shown that a particular age-group tends to reside in a particular locale or community and the effect possesses usually statistical significance. We quantitatively address this issue: how certain division of age group resides in different region of the country, and investigate possible cause of this migration pattern for different age groups. In this study, population migration trend at age groups of 20s, 30s, 40s and 50s has been analyzed incorporating a spatial econometrics model that accounts for diverse statistical pitfalls such as spatial autocorrelation and spatial dependency. We found that migration trend for different age group corresponds to regional characteristics differently. The study concludes with some policy implications and suggests a need of further study.

• Journal of the Korean association of regional geographers
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• v.16 no.5
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• pp.590-609
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• 2010

The purpose of the study is to propose and evaluate Exploratory Spatial Data Analysis(ESDA) methods for examining age-specific population migration characteristics. First, population migration pyramid which is a pyramid-shaped graph designed with in-migration, out-migration, and net migration by age (or age group), was developed as a tool exploring age-specific migration propensities and structures. Second, various spatial statistics techniques based on local indicators of spatial association(LISA) such as Local Moran''s $I_i$, Getis-Ord ${G_i}^*$, and AMOEBA were suggested as ways to detect spatial dusters of age-specific net migration rate. These ESDA techniques were applied to age-specific population migration of Daegu Metropolitan City. Application results demonstrated that suggested ESDA methods can effectively detect new information and patterns such as contribution of age-specific migration propensities to population changes in a given region, relationship among different age groups, hot and cold spot of age-specific net migration rate, and similarity between age-specific spatial clusters.

• The Journal of the Korea Contents Association
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• v.21 no.12
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• pp.310-321
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• 2021

The influence of regional economic growth on migration may also differ by age and generation age due to individual lifestyle. Therefore, this study analyzes an effects of changes in regional economic growth on migration between regions by age group. The result shows that the increase in the growth rate of the regional economy and job creation increased the net migration rate, regardless of age group. Second, it is found that the growth rate of the regional economy and job creation have a greater effect on the net migration rate for the youth population than for the middle-aged group. Third, it is found that the gap between regions in the level of individual income in the 25 to 29 years old and the level of land price fluctuations in the 40 to 64 years old affect the net migration rate. This implies that regional economic growth is still an important factor in the migration between regions, and has a great influence on the youth population.

• Journal of the Korean Geographical Society
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• v.49 no.5
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• pp.728-746
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• 2014

The purpose of this study is to analyze the influence of the selective migration of young age group and the stage migration which has proceeded through generations, on the transition of fertility and the population growth in the rural and urban in the case of Jeollabuk-do. For this, we use O-D matrix of 20-34 age group, the distribution of that group and women of child bearing age, and vital statistics in 1970-2010. The major findings of this study are as follows. First, the outflows from their birth place are common and dominant features of 20-34 age group in each time. Second, there is the stage migration which preceding generation moved from the rural areas to the cities in Jeollabuk-do and following generation has moved from the cities to Seoul metropolitan area. Third the selective outflow migration of young age group has leaded to reduction of the childbearing population, declining birthrate, aging and natural population decline. Due to the stage migration, these depopulation processes occurred in rural area in the past, and currently it expands to the cities with about 15 years time gap. In fact, there have been the natural population decrease which annual number of deaths exceed that of births from the late 1980s in the most rural areas and in the early 2000s, such a phenomenon has been confirmed also in urban areas. Therefore, this study concludes that the stage migration through generations is one of the crucial factor to the population growth in local cities and also brings out the step-wise population decrease in settlement hierarchies.

• Journal of Integrative Natural Science
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• v.15 no.3
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• pp.131-136
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• 2022

Cell migration is essential for diverse cellular processes including wound healing, immune response, development, and cancer metastasis. Pi3-kinase (PI3K) is a key regulator for actin cytoskeleton and phosphorylates phosphatidylinositol (4,5)-diphosphate (PIP2) to phosphatidylinositol (3,4,5)-trisphosphate (PIP3). High levels of PIP3 by PI3Ks are associated with increased levels of F-actin and pseudopod extension at the leading edge of migrating cells such as neutrophils and Dictyostelium. LY294002 is a well-known PI3K specific inhibitor. Here, we investigated the effect of LY294002 on cell migration. First, we evaluated the appropriate concentration of dimethyl sulfoxide (DMSO) for using as a solvent for LY294002. DMSO is a highly polar organic reagent and one of the most common solvent for organic and inorganic chemicals. Cell morphology and cell migration were unaffected at the concentrations less than 0.1 % DMSO. Therefore, stock solution of LY294002 was prepared so that the final concentration of DMSO was 0.1 % or less when treated. When cells were treated with LY294002, cell migration was increased in a concentration-dependent manner. The maximum speed was detected in the presence of 30 µM LY294002. These results suggest that PI3Ks play a inhibitory role in regulating cell migration in our experimental conditions.

• Journal of Veterinary Clinics
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• v.37 no.3
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• pp.115-122
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• 2020

The aim of this study was to evaluate double-pigtail ureteral stent fixation in cats. Medical records of 19 cats (23 ureters) with complete ureteral obstruction that double-pigtail ureteral stent placement were carried out were retrospectively reviewed. The cats were randomly classified into two groups; 13 cats (16 ureters) with double-pigtail ureteral stent fixed to urinary bladder (SF group) and 6 cats (7 ureters) with not fixed to urinary bladder (SNF group). The average age and weight of the cats was 7.4 years and 3.73 kg, respectively. Postoperative complications included chronic renal failure (n = 11), lower urinary track diseases (cystitis, hematuria, pollakiuria) (n = 7), stent migration (n = 6), anemia (n = 5), ascites (n = 2), hyperthermia (n = 1), enteritis (n = 1), oliguria (n = 1), hypotension (n = 1), ureteritis (n = 1), and pyelonephritis (n = 1). Stent migration did not occur in the 16 ureters of the cats in SF group but did occur in 4 out of 7 ureters of the cats in SNF group. The prevention of stent migration by stent fixation was significant (P = 0.04). Among the 13 cats in SF group, only 2 cats developed lower urinary track diseases, while 4 of the 6 cats in SNF group showed symptoms of lower urinary track disease. Thus, the cats that underwent double-pigtail ureteral stent fixation to the urinary bladder developed significantly fewer lower urinary diseases (P = 0.046). In conclusion, double-pigtail ureteral stent fixation to the urinary bladder for treatment of complete ureteral obstruction in cats can effectively prevent stent migration, which is common complication of stent placement.

• Korean Journal of English Language and Linguistics
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• v.3 no.1
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• pp.15-36
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• 2003

This paper investigates the patterns of language choice among bilingual Korean students in New Zealand and presents the findings by the individual variables which influence their language behaviour. Respondent variables such as gender, present age, age at migration, region, and duration of residence were adopted as frames of analyses as they were thought to bring us macro-sociolinguistic features of language behaviour in a broad sense. A total of 177 primary to tertiary students from three regions of New Zealand (Auckland, Wellington, and Christchurch) were surveyed to find out characteristics of their language choice patterns with diverse interlocutors in a wide range of contexts. It was found that the younger AAM (age at migration) group showed a greater shift towards English. In addition, the longer the respondents had resided in New Zealand the more they used English. The results also revealed that females generally used less English and were more flexible choosing either Korean or English according to the situation. The younger respondents were using more English in some exceptional contexts where tertiary students were ahead of secondary students. Respondents from Wellington, on the whole, shifted towards English more than others from Auckland, and Christchurch. From these findings some implications are suggested for Korean students, teachers, researchers, and the government not only in New Zealand but also in Korea.

• Land and Housing Review
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• v.11 no.1
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• pp.21-38
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• 2020

This study examined the population movement of the young generation in accordance with the characteristics of housing market focusing on the housing problem of youth issues. Targeting 64 local governments in the seoul metropolitan area, the temporal range was decided as 2015. Setting up the rising population in 19-34 as a dependent variable, supposing that each age group shows different characteristics, it was divided into age groups in 19~34, 19~29, and 25~34. The population movement of the young generation in accordance with the characteristics of housing market was considered through the multiple regression analysis. In the results, the population movement of the young generation was influenced by the change in detached multi-family housing and the rate of housing supply. The increase of detached multi-family housing promoted the population inflow of the young generation while the population movement of the young generation was disturbed by the rising rate of housing supply. Also, when the local characteristics are not controlled, the young generation hesitates to enter the region where relatively high rent should be paid while the new housing supply focusing on apartment is hard to be selected by the young generation for residence because of the size and price. The population movement of the young generation looked quite different in each age group. The population inflow of the young generation in 19~29 was influenced when there were many officetels and non-apartments on top of detached multi-family housing. On the contrary, the population movement of the young generation in 25~34 was significantly influenced by the increase of the whole size of completed apartment area. Even though it was not the research subject of this study, among control variables, the financial independence and daily average number of get-on/off had effects on the movement of the young generation. It means that the housing type preferred by college students and social novices is different from the housing type preferred by the group with experiences in marriage and childbirth within the same young generation. Thus, it would be necessary to divide the purposes of policies for each subject when executing the youth housing policies.

• Journal of the Korean association of regional geographers
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• v.13 no.6
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• pp.651-673
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• 2007

In the studies on residential move, there has been tendency of dichotomy where short distance moves are largely caused by housing to adjust to changes in households while long distance moves are induced by shift in labor market. However, some empirical studies have proven that residential move is so complex process that the simple dichotomy should be elaborated. In this sense, the present study seeks to identify compounded course of residential move in Korea. In determining migration history, families with younger householders, renters, householders with higher educational attainment and smaller households show a higher probability to move. In case of mobility, women were more prone to move compared to man. Women compared to man, older age augmented the probability to own a house after migration. Families with householders following an occupation of sales and technical service showed lowest tendency to own houses while it marked the highest in the group of professionals. Higher land price of a region was negatively related to owning houses after migration. The present study revealed that factors in macro level as well as micro level significantly affect the move of individuals with varying effects in accordance with migration history.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.7
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• pp.3507-3511
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• 2012

Objective: The aim of this study was to investigate possible mechanisms of LOX gene effects on invasion and metastasis of breast cancer cells by RNA interference. Methods: LOX-RNAi-LV was designed, synthesized, and then transfected into a breast cancer cell line (MDA-MB-231). Expression of LOX, MMP-2 and MMP-9 was determined by real-time PCR, and protein expression of LOX by Western blotting. Cell migration and invasiveness were assessed with Transwell chambers. A total of 111 cases of breast cancer tissues, cancer-adjacent normal breast tissues, and 20 cases of benign lesion tissues were assessed by immunohistochemistry. Results: Expression of LOX mRNA and protein was suppressed, and the expression of MMP-2 and MMP-9 was significantly lower in the RNAi group than the control group (P<0.05), after LOX-RNAi-LV was transfection into MDA-MB-231 cells. Migration and invasion abilities were obviously inhibited. The expression of LOX protein in breast cancer, cancer-adjacent normal breast tissues and benign breast tumor were 48.6% (54/111), 26.1% (29/111), 20.0% (4/20), respectively, associations being noted with clinical stage, lymph node metastasis, tumor size and ER, PR, HER2, but not age. LOX protein was positively correlated with MMP-2 and MMP-9. Conclusion: LOX displayed an important role in invasion and metastasis of breast cancer by regulating MMP-2 and MMP-9 expression which probably exerted synergistic effects on the extracellular matrix (ECM).