• 한국지능정보시스템학회:학술대회논문집
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• 한국지능정보시스템학회 2001년도 The Pacific Aisan Confrence On Intelligent Systems 2001
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• pp.385-392
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• 2001

This paper proposes a meta modeling technique which permits to describe a KBS according to three axis: the object of reuse axis, the levels of granularity axis and the reuse process axis. The object of reuse axis allows to see a KBS as a set of inter-related components for reuse purposes. The levels of granularity axis allows to describe the KBS components according to different levels of granularity for clarity and reuse purposes. The reuse process axis allows to see the KBS components as (re)usable components.

• Biotechnology and Bioprocess Engineering:BBE
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• 제10권5호
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• pp.425-431
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• 2005

The systems-level analysis of microbes with myriad of heterologous data generated by omics technologies has been applied to improve our understanding of cellular function and physiology and consequently to enhance production of various bioproducts. At the heart of this revolution resides in silico genome-scale metabolic model, In order to fully exploit the power of genome-scale model, a systematic approach employing user-friendly software is required. Metabolic flux analysis of genome-scale metabolic network is becoming widely employed to quantify the flux distribution and validate model-driven hypotheses. Here we describe the development of an upgraded MetaFluxNet which allows (1) construction of metabolic models connected to metabolic databases, (2) calculation of fluxes by metabolic flux analysis, (3) comparative flux analysis with flux-profile visualization, (4) the use of metabolic flux analysis markup language to enable models to be exchanged efficiently, and (5) the exporting of data from constraints-based flux analysis into various formats. MetaFluxNet also allows cellular physiology to be predicted and strategies for strain improvement to be developed from genome-based information on flux distributions. This integrated software environment promises to enhance our understanding on metabolic network at a whole organism level and to establish novel strategies for improving the properties of organisms for various biotechnological applications.

• 한국산학기술학회논문지
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• 제17권3호
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• pp.117-126
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• 2016

본 연구에서는 안경의 광학적 특성에서 고안된 새로운 메타휴리스틱 최적화 알고리즘인 Vision Correction Algorithm(VCA)을 개발하였다. VCA는 안경광학분야에서 수행되는 검안과 교정과정을 최적해 탐색 과정에 적용한 기법으로 근시/원시교정-밝기조정-압축시행-난시교정의 과정을 거쳐 최적화를 수행하게 된다. 제안된 VCA는 기존의 메타휴리스틱 알고리즘과 달리 현재까지 축적된 최적화 결과를 기반으로 전역탐색과 국지탐색 적용 확률, 그리고 전역탐색의 방향이 자동적으로 조정 된다. 제안된 방법을 대표적인 최적화 문제(수학 및 공학 분야)에 적용하고, 그 결과를 기존 알고리즘들과 비교하여 제시하였다.

• 대한간호학회지
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• 제27권4호
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• pp.857-870
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• 1997

The purposes of this study were to describe 12 years of patient-related oncology nursing research in Korea, identifying various nursing interventions, and assesing the effectiveness of the interventions, through analysis and synthesis of the accumulated research papers. One hundred and seventy-nine studies were selected for this study and these were mostly descriptive in design (69.2%). Of the 179 studies, 25 met the criteria for meta-analytic treatment. Twenty-five experimental studies were found in theses and dissertations (68%), 92% used convenience sample, and the median sample size was 40. Subjects were predominantly in treatment and rehabilitation (76%). Most studies(68%) were not derived from a theory base, with only 8% reporting use of a nursing theory. Results of the meta-analysis are as follows. The effect size of the nursing intervention type was found to be significantly effective. The standardized mean difference ranged from a high positive of 2.55 to a low negative of -0.22. Direct personal nursing intervention method was more effective than indirect group method. Two nursing intervention methods were more effective than one. The greatest effect size was thyxical intervention. The greatest mean effect size was scalp hypothermia technique. Teaching was a frequent intervention after 1990, although a wide range of treatments were studied. Effect size of intervention for symptom management was largest in relieving pain. Effective intervention method for relieving anxiety was exercise.

• Genomics & Informatics
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• 제14권4호
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• pp.173-180
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• 2016

The meta-analysis has become a widely used tool for many applications in bioinformatics, including genome-wide association studies. A commonly used approach for meta-analysis is the fixed effects model approach, for which there are two popular methods: the inverse variance-weighted average method and weighted sum of z-scores method. Although previous studies have shown that the two methods perform similarly, their characteristics and their relationship have not been thoroughly investigated. In this paper, we investigate the optimal characteristics of the two methods and show the connection between the two methods. We demonstrate that the each method is optimized for a unique goal, which gives us insight into the optimal weights for the weighted sum of z-scores method. We examine the connection between the two methods both analytically and empirically and show that their resulting statistics become equivalent under certain assumptions. Finally, we apply both methods to the Wellcome Trust Case Control Consortium data and demonstrate that the two methods can give distinct results in certain study designs.

• 보건교육건강증진학회지
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• 제23권3호
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• pp.1-16
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• 2006

Objectives: To analyze the characteristics of smoking prevention programs for the adolescent, and to synthesize the common effect sizes on smoking prevention programs for the adolescent. Methods: Seventeen studies for meta-analysis were selected from dissertations, these, and papers that had been published from 1996 to 2005 and had a randomized or nonequivalent control group in a pre test-post test design. The analysis of the data was computed by using the meta-analysis software package developed by Song(2003). Results: Smoking prevention programs for the adolescent have resulted in a significant effect size on smoking-knowledge( .62), smoking-attitude( .55) of smoking prevention programs for the adolescent showed more than 'medium effect' size. In smoking-knowledge and amount of smoking, the effect size was smoking-attitudes, the effect size was large in the studies which consists of more than 10 sessions of intervention. Conclusion: From the above results, we notice that the smoking prevention programs for the adolescent were effective in increasing the smoking-knowledge, smoking-attitudes, and the intention of smoking-cessation.

• 대한통합의학회지
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• 제5권1호
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• pp.55-66
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• 2017

Purpose : The purpose of this study was to investigate whether mindful meditation programs conducted in ACT(Acceptance &Commitment Therapy) and MBCT(Mindfulness-Based Cognitive Therapy) were effective in changing in depression and anxiety. Methods : In order to achieve this, we have performed meta-analysis of the studies on ACT and MBCT among studies published in the national academic journals, master thesis, and doctoral thesis. Dependent variables were limited to depressive and anxiety symptoms. By using meta analysis method, we retrieved journal articles published in Korea between 2009 and 2015 using keyword searches of electronic databases. Result : The results of the analysis showed that both ACT and MBCT had a significant effect on reducing depressive symptoms (Hedges' g = -0.71, p < 0.01). Both also had a significant effect on reducing anxiety symptoms (Hedges' g = -1.134, p < 0.01). These results imply that both ACT and MBCT interventions can be useful interventions for both depressive and anxiety symptoms. In the case of interventions for depressive symptoms, the college student group showed better results than the adult group. In addition, the ACT program had a stronger effect on reducing depressive symptoms than the MBCT program. In the case of interventions for anxiety symptoms, the mixed gender group showed better results than the female group. Conclusion : The results showed significant differences with regard to the following factors: participant gender, target participants, mindfulness technique availability, session number, and session duration.

• 대한수학교육학회지:학교수학
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• 제16권3호
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• pp.409-444
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• 2014

수학교육 연구 공동체에서는 모델링 활동을 통한 수학 학습에 대한 논의들이 지속되어 왔다. 모델링 활동은 대안적인 수학 교수 학습 방법으로 논의되어 왔으나, 모델링 활동을 통하여 이루어지는 수학 학습은 어떠한 성격을 갖는지, 그리고 이는 어떠한 과제 설계와 수업 실행을 통하여 달성할 수 있는지에 대한 합의점은 도출되지 못한 실정이다. 모델링 활동을 통한 수학 학습을 시도해 온 선행 연구들의 논의로부터, 본 연구에서는 모델링 활동이 메타수준의 수학적 담론 생성과 메타규칙의 변화를 포함하는 메타수준 학습을 촉진할 수 있을 것으로 판단하였다. 이에 본 연구에서는 메타수준 학습을 촉진할 수 있는 모델링 과제 설계와 수업 실행 방안을 도출하고, 이를 실행하여 수학 교수 학습에서 모델링 활동의 잠재력을 확인하는 데 목적을 둔다.

• 산업공학
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• 제17권3호
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• pp.330-337
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• 2004

Since XML (eXtensible Markup Language) was highlighted as an information interchange format, there is an increasing demand for incorporating XML with databases. Most of the approaches are focused on RDB (Relational Databases) because of legacy systems. But these approaches depend on the database system. Countless researches are being focused on DTD (Document Type Definition). However XML Schema is more comprehensive and efficient in many perspectives. We propose a meta-model for XML Schema that is independent of the database. There are three processes to build our meta-model: DOM (Document Object Model) tree analysis, object modeling and storing object into a fixed DB schema using model mapping approach. We propose four mapping rules for object modeling, which conform to the ODMG (Object Data Management Group) 3.0 standard. We expect that the model will be especially useful in building XML-based e-business applications.

• 한국도서관정보학회지
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• 제33권2호
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• pp.109-137
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• 2002

해양 전자정보자원 메타 데이터베이스 시스템 설계 및 구현을 위해 국내외 관련 연구를 조사하고 분석하였다. 연구대상은 해양분야 웹 자원에서 해양조사자료가지를 범위로 하였다. 본 연구의 목적은 네트워크 자원의 기술에 적합한 더블린코어를 기반으로 효율적인 해양분야 전자정보자원 정보검색서비스를 제공하는데 있다. 본 논문에서는 해양분야 전자정보원 조사, 메타데이터 기술요소 분석, 베타데이터 분류체계, 시스템 구성 및 검색 구현방안의 연구를 수행하였다.