• Journal of Korean Medicine Rehabilitation
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• v.30 no.3
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• pp.89-101
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• 2020

Objectives The purpose of this study is to assess the effectiveness of Chuna manual therapy for shoulder pain in hemiplegic patients after stroke. Methods For a systematic review and meta-analysis, we set a key question in accordance with participants, intervention, comparison, outcome, study design (PICO-SD). we searched for clinical studies that conducted chuna manual therapy for shoulder pain in hemiplegic patients after stroke 7 databases until September 2019. Only randomized controlled trials were chosen. Results Total 14 randomized controlled trials were chosen for systematic review and meta-analysis. 9 studies used efficacy rate as evaluation tool, and 8 used visual analogue scale. Pressure method (壓力型) was used in 11 studies, followed by osteopathy method (整骨型) and wave motion method (波動型) in 9 studies. Chuna manual therapy showed statistically significant pain reduction effect. Through meta analysis, Chuna manual therapy showed significant pain reducing effect except the study with Chuna manual therapy and electroacupuncture compared to electroacupuncture only. Conclusion As a result, Chuna manual therapy showed statistically significant effect in pain reduction. However, almost studies were evaluated in a state of having probable high risk of bias. This suggests that it requires attention to make an interpretation in this study. Furthermore, more clinical research need to be accomplished in the future.

• Journal of Digital Convergence
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• v.16 no.2
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• pp.151-156
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• 2018

The purpose of this study is to conduct a meta-analysis of 18 papers that can be verified among the papers on the subject of TPM. Five hypotheses were set for the analysis and meta - analysis was carried out with CMA as presented in each research paper. As a result of analysis, I-square value is more than 75% in four hypotheses. Therefore, the null hypothesis that the size of the population effect is the same for all studies was rejected. The reason for the heterogeneity is that the research characteristics such as the distribution of the respondents, the study conditions, the study period, and the study area are different. In this case, a summary statistic of the individual studies that can be classified according to the characteristics of the research is needed to analyze the effect size difference. However, individual studies do not provide a summary statistic that can classify the effect differences, so it is not possible to analyze the causes of heterogeneity.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.5
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• pp.2363-2367
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• 2014

The association between the NAD(P)H:quinone oxidoreductase 1 (NQO1) gene C609T polymorphism (rs1800566) and gastric cancer has been widely evaluated, but a definitive answer is so far lacking. We first conducted a case-control study to assess this association in a large Han Chinese population, and then performed a meta-analysis to further address this issue. Although our case-control association study indicated no significant difference in the genotype and allele distributions of C609T polymorphism between gastric cancer patients and controls, in the meta analysis involving 4,000 subjects, comparison of alleles 609T and 609C indicated a significantly increased risk (46%) for gastric cancer (95% confidence interval (95%CI) for odds ratio (OR)=1.20-1.79) in individuals with the T allele. The tendency was similar to the homozygote (OR=1.81, 95%CI: 1.16-2.84), dominant models (OR=1.41, 95%CI: 1.12-1.79), as well as recessive model (OR=1.58, 95%CI: 1.06-2.35). Stratified analysis by study design demonstrated stronger associations in population-based than in hospital-based studies. And ethnicity-based analysis demonstrated a significant association in Asians. We conclude that the NQO1 gene C609T polymorphism increases the risk for gastric cancer, especially in Asian populations.

• Journal of Oriental Neuropsychiatry
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• v.31 no.3
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• pp.169-186
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• 2020

Objectives: The purpose of this study was to provide clinical evidence to support the use of acupuncture combined herbal medicine for post-stroke depression. Methods: Studies were identified by searching Pubmed, EMBASE, Cochrane Library, NDSL, RISS, KMbase, KISS, and CNKI. Randomized controlled trials that verified effects of the acupuncture combined with the herbal medicine for PSD were included in this study. Literature searches of English, Chinese, and Korean databases were performed. Two authors independently extracted the data and assembled the study quality. Results: Of 698 RCTs screened, 17 RCTs were selected. Most of the studies had unclear risk of bias. Among the 17 RCTs, 10 were meta-analyzed. As for the outcome measurement, the effective rate and the HAMD were most commonly used. The meta-analysis of the studies revealed that the PSD cure effective rate in the acupuncture combined with herbal medicine group was higher than that in the Western medicine group (RR: 1.23, 95% CI: 1.14 to 1.33, p<0.00001, I²=0%). Also, the HAMD in the acupuncture combined with herbal medicine group was significantly different compared to the Western medicine group (MD -5.54, 95% CI -9.80 to -1.29, p=0.01, I²=99%). The quality of the selected RCTs was low. Conclusions: Acupuncture combined with herbal medicine is effective for treating post-stroke depression. However, It is worth noting that the included studies were of relatively poor quality. The sample sizes were also small. Based on the findings of this study, further investigations into the diagnosis and treatment of PSD are warranted.

• The Journal of Korean Academy of Prosthodontics
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• v.41 no.2
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• pp.160-168
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• 2003

Statement of problem : Direct denture reline resins tend to discolor during service in the oral environment by intrinsic and extrinsic factor. Purpose : This study was designed to evaluate the color stability of direct denture reline resins. Material and methods : Mild Rebaron(GC Corp., Japan), Meta Base M(Sun medical Co., Japan), Mild Rebaron LC(GC Corp., Japan) and as a control group, Vertex SC(Dentimex Zeist, Holland) were chosen for this study. Ten specimens of each direct denture reline resins were fabricated. Treatment methods designed for this study were the coffee staining test(7days) and the accelerated aging test(100hours). The color changes before and after treatment were measured by Tristimulous colorimeter(Yasuda seiki seisakusho, Ltd. Japan) and analyzed. Results All the direct denture reline resins subjected to the coffee staining test and the accelerated aging test showed noticible difference in color change. After coffee staining test, Meta Base M showed the highest color change followed by Vertex SC. Mild Rebaron LC and Mild Rebaron. There were no statistical differences between Meta Base M and Vertex SC and between Mild Rebaron LC and Mild Rebaron(p>0.05). After accelerated aging test. Mild Rebaron LC showed the highest color change followed by Vertex SC, Meta Base M and Mild Rebaron. There were no statistical differences only between Mild Rebaron and Mata Base M(p>0.05) but among the others, there were statistical differences(p<0.05). Conclusion : Within the limitation of this study, all the direct denture reline resins subjected to the extrinsic and intrinsic factors showed noticible difference in color change, and there were differences among manufacturers.

• Journal of the Korean Society for Library and Information Science
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• v.38 no.2
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• pp.189-212
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• 2004

The purpose of this study is to design the meta search system and the curriculum-oriented directory system for youth in science and to prove the efficiency of the systems through evaluating the usability. To attain the purpose of this study, both of the quality and quantity research method were used and questionnaire, interview. observation, thinking aloud method were used to collect a data for research. The result of this study is that the meta search system supplying convenient information use environment about the distributed information sources has higher usability than the individual search system. And the curriculum-oriented directory system supplying accessibility related with the class has higher usability than the subject-oriented directory system.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.11
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• pp.7273-7284
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• 2015

The purpose of this study was to investigate the effect size of non-pharmacological intervention applied to patients with anxiety disorder and to provide information about evidence-based intervention. Twenty three studies were selected for meta-analysis through a systematic review of domestic studies. We searched journal articles published in Korea up to May, 2015 using the key words "Anxiety Disorders (MeSH)" and "Treatment or Intervention". Meta-analysis was performed using a random effects model, and the effect sizes on each of anxiety and depression were calculated. The effect size for anxiety of non-pharmacological intervention in this study was Hedges' g=1.693 (95% CI; 1.267-2.120), indicating a large effect size. The effect size for depression was Hedges's g=1.571 (95% CI; 0.481-2.661), indicating a large effect size. It is significant that this study systematically synthesized the study results for non-pharmacological intervention effects applied to patients with anxiety disorders in Korea. It also established a basis that can be applied to nursing intervention.

• Journal of Preventive Medicine and Public Health
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• v.30 no.3 s.58
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• pp.643-664
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• 1997

This study is to provide evidence-based recommendations for the most-effective treatments of benign prostatic hyperplasia based on patient preference or clinical need, and to meta-analyze the Korean literatures for the development of BPH treatment guidelines. For these analyses, extensive literature searches (208 articles), with priority given to the Korean Journal of Urology, were conducted from 1960 to August, 1996. Meta-analysis, like all statistical analysis, has two main functions: data summarization (qualitative meta-analysis) and smoothing o. pattern recognition (quantitative meta-analysis). As well, critical reviews and syntheses with the mean and 90-percent confidence intervals for the likelihood were used to evaluate empirical evidence and significant outcomes of the BPH treatment literatures (106 articles). For this task, the Methodologic Panel for BPH Guidelines was composed of multidisciplinary experts in the field. The results of the study were summarized as follows: For all that watchful waiting is an appropriate treatment strategy for the majority of patients with prostatism, we couldn't find the Korean literatures which carried this article. The literatures on alpha-1-adrenergic receptor blockers provide no evidence to suggest that any one alpha blocker is more effective than another. The finasteride reduces the size of the prostate, on average, and leads to a small yet perceptible reduction in sysptoms. Of all treatment options, prostate surgery with transurethral resection of the prostate (TURP), transurethral incision of the prostate (TUIP), and so on, offers the best chance for symptom improvement. However, surgery also has the highest rates of significant complications. Therefore, surgery need not always be a treatment of last resort. Balloon dilation of the prostatic urethra is clearly less effective than surgery in relieving symptoms, but it is associated with fewer complications. Emerging technologies for treating BPH include lasers, coils, stents, thermal therapy and hyperthermia. Established technologies will also be reanalyzed as results of new trials are reported. Although this study has some limitations due to lacking for good quality literatures, ' it provides a cornerstone for our medical research. It represents the most current scientific knowledge regarding the clinical epidemiology including treatment of BPH. It will be revised and updated as needed.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.10
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• pp.158-167
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• 2016

This study was conducted to evaluate the quality of meta-analysis of social work in South Korea using the Assessment of Multiple Systematic Review (AMSTAR). Electronic databases including the Korean Studies Information Service System (KISS), DBpia, and RISS4U were searched for 'meta-analysis', 'social work', and 'social welfare' from 2000 to December 2015, and 42 meta-analysis studies were included. Data were analyzed using descriptive statistics, t-tests, and ANOVA. The mean score for AMSTAR evaluation was $4.766{\pm}1.66$, while 19 studies (45.2%) were classified at the low-quality level, and 22 (52.4%) were at the moderate-quality level. The scores of quality assessment were analyzed by publication year, participants, number of studies included, number of DB, reporting study quality, extraction diagram and topics. The findings indicated that the following changes should be implemented to improve the quality and reliability of meta-analysis results in social work research: 1) common reporting guidelines should be provided for the social work field, 2) quality analyses of each study should be conducted to achieve a high level of evidence of effectiveness of social work interventions, 3) the characteristics of the included studies should be provided, and 4) a consensus and procedure based on at least two independent data extractors should be reported.

• The Journal of the Korea Contents Association
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• v.18 no.12
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• pp.535-546
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• 2018

This study conducted a meta-analysis to examine syntagmatically on the variables related with recovery among persons with mental illness in Korea. In order to do a meta-analysis, theses and dissertations published between 1999 and 2018 in Korea were reviewed systematically and a total of 24 including studies were selected. Using Comprehensive Meta Analysis (CMA) 3.0 software, this study calculated average effect size and moderator variables related with recovery among persons with mental illness. Results were as follows. First, this study identified a total of 16 variables related with recovery among persons with mental illness. Second, the results indicated that variables which showed large effect sizes included social support(r=.575), empowerment(r=.555), self-efficacy(r=.544), social skill(r=.500), relationship with social worker(r=.482), stigma(r=-.446), family support(r=.418). Third, variables with medium effect sizes included interpersonal relationship capacity (r=.391), agency service satisfaction(r=.366), insight(r=.373) and symptom(r=-.239). Fourth, variables with small effect sizes included work experience(r=.188). Fifth, moderator analyses were conducted utilizing characteristics of residence state (community or mental hospital). Moderator effects were identified in the social support and family support. Based on the findings, theoretical and clinical implications for the recovery among persons with mental illness in Korea were discussed.