• Title/Summary/Keyword: Medical optics

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Development and Possibility Evaluation of Thermal Imaging Camera for Medical Monitoring of Body Temperature (열화상카메라 개발을 통한 의료용 체열진단 가능성 평가)

  • Ryu, Seong Mi;Kim, Hye-Jeong
    • Journal of Korea Society of Industrial Information Systems
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    • v.20 no.1
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    • pp.57-62
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    • 2015
  • Recently, thermography camera have been using for body-temperature monitoring. We report on fabrication of prototype thermography camera using the chalcogenide-glass lens and the camera test by analysis of thermal image. In this work, it was found out that thermography camera discerned body-temperature between 20 and $50^{\circ}C$ with noise equivalent temperature difference(NETD) of 87.7mK. It is confirmed that thermography camera using the chalcogenide-glass lens is applicable to the body-temperature monitoring system.

Thermal Lens Compensation in a Fiber-Coupled Laser-Diode Pumped Ceramic Nd:YAG Laser (광섬유 연결 반도체레이저 여기 세라믹 Nd:YAG 레이저에서 열렌즈 효과의 보상)

  • Kim, Duck-Lae;Kim, Yeong-Sik;Kim, Byung-Tai
    • Korean Journal of Optics and Photonics
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    • v.18 no.3
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    • pp.208-215
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    • 2007
  • A fiber-coupled laser-diode pumped ceramic Nd:YAG laser for compensating the thermal tensing effect was developed. The thermal tensing effect was compensated using a convex lens, which was 25 mm away from the laser rod, with a focal length of 30 mm and an effective clear aperture of 22 mm. Without a compensator, the laser output power decreased suddenly above a pump power of 6 W. Using a compensator, the laser output power increased linearly according to the pump power. The beam propagation factor $M^{2}$ was 2.4 under a pump power of 12 W.

Stiffness Comparison of Tissue Phantoms using Optical Coherence Elastography without a Load Cell

  • Chae, Yu-Gyeong;Park, Eun-Kee;Jeon, Min Yong;Jeon, Byeong-Hwan;Ahn, Yeh-Chan
    • Current Optics and Photonics
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    • v.1 no.1
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    • pp.17-22
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    • 2017
  • Mechanical property of tissue is closely related to diseases such as breast cancer, prostate cancer, cirrhosis of the liver, and atherosclerosis. Therefore measurement of tissue mechanical property is important for a better diagnosis. Ultrasound elastography has been developed as a diagnostic modality for a number of diseases that maps mechanical property of tissue. Optical coherence elastography (OCE) has a higher spatial resolution than ultrasound elastography. OCE, therefore, could be a great help for early diagnosis. In this study, we made tissue phantoms and measured their compressive moduli with a rheometer measuring the response to applied force. Uniaxial strain of the tissue phantom was also measured with OCE by using cross-correlation of speckles and compared with the results from the rheometer. In order to compare stiffness of tissue phantoms by OCE, the applied force should be measured in addition to the strain. We, however, did not use a load cell that directly measures the applied force for each sample. Instead, we utilized one silicone film (called as reference phantom) for all OCE measurements that indirectly indicated the amount of the applied force by deformation. Therefore, all measurements were based on displacement, which was natural and effective for image-based elastography such as OCE.

Characterization of Thickness and Electrical Properties of Ni-Cr Thin Films via Terahertz Time-domain Spectroscopy

  • Sunghun Kim;Inhee Maeng;Hyeon Sang Bark;Jungsup Byun;Jae Hun, Na;Seho Kim;Myeong Suk Yim;Byung-Youl Cha;Youngbin Ji;Seung Jae Oh
    • Current Optics and Photonics
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    • v.7 no.5
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    • pp.569-573
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    • 2023
  • We utilized terahertz time-domain spectroscopy (THz-TDS) to measure the thickness and electrical properties of nickel-chromium (Ni-Cr) films. This technique not only aligns well with traditional methods, such as haze-meter and transmission-densitometer measurements, but it also reveals the electrical properties and thickness of films down to a few tens of nanometers. The complex conductivity of the Ni-Cr thin films was extracted using the Tinkham formula. The experimental values closely aligned with the Drude model, indicating the reliability of our Ni-Cr film's electrical and optical constants. The thickness of Ni-Cr was estimated using the complex conductivity. These findings emphasize the potential of THz-TDS in quality control of metallic nanofilms, pointing toward an efficient and nondestructive test (NDT) for such analyses.

Clinical Utility of an Automated Pupillometer in Patients with Acute Brain Lesion

  • Park, Jeong Goo;Moon, Chang Taek;Park, Dong Sun;Song, Sang Woo
    • Journal of Korean Neurosurgical Society
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    • v.58 no.4
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    • pp.363-367
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    • 2015
  • Objective : The purpose of this study was to evaluate the clinical utility and validity of using a pupillometer to assess patients with acute brain lesions. Methods : Pupillary examinations using an automated pupillometer ($NeurOptics^{(R)}NPi^{TM}$-100 Pupillometer) were performed every 4 hours and were simultaneously assessed using the Glasgow Coma Scale (GCS) and for intracranial pressure (ICP), from admission to discharge or expire in neuro-intensive care unit (NICU). Manual pupillary examinations were also recorded for comparison. By comparing these data, we evaluated the validity of using automated pupillometers to predict clinical outcomes. Results : The mean values of the Neurologic Pupillary index (NPi) were different in the groups examined manually. The GCS correlated well with NPi values, especially in severe brain injury patients (GCS below 9). However, the NPi values were weakly correlated with intracranial pressure (ICP) when the ICP was lower than 30 cm $H_2O$. The NPi value was not affected by age or intensity of illumination. In patients with a "poor" prognosis who had a Glasgow Outcome Scale (GOS) of 1 or 2, the mean initial NPi score was $0.88{\pm}1.68$, whereas the value was $3.89{\pm}0.97$ in patients with a "favorable" prognosis who had a GOS greater than 2 (p<0.001). For predicting clinical outcomes, the initial NPi value of 3.4 had the highest sensitivity and specificity. Conclusion : An automated pupillometer can serve as a simple and useful tool for the accurate measurement of pupillary reactivity in patients with acute brain lesions.

Transforming growth factor-beta and liver injury in an arginine vasopressin-induced pregnant rat model

  • Govender, Nalini;Ramdin, Sapna;Reddy, Rebecca;Naicker, Thajasvarie
    • Clinical and Experimental Reproductive Medicine
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    • v.48 no.2
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    • pp.124-131
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    • 2021
  • Objective: Approximately 30% of preeclamptic pregnancies exhibit abnormal liver function tests. We assessed liver injury-associated enzyme levels and circulating transforming growth factor beta (TGF-β) levels in an arginine vasopressin (AVP)-induced pregnant Sprague-Dawley rat model. Methods: Pregnant and non-pregnant Sprague-Dawley rats (n=24) received AVP (150 ng/hr) subcutaneously via mini-osmotic pumps for 18 days. Blood pressure was measured, urine samples were collected, and all animals were euthanized via isoflurane. Blood was collected to measure circulating levels of TGF-β1-3 isomers and liver injury enzymes in pregnant AVP (PAVP), pregnant saline (PS), non-pregnant AVP (NAVP), and non-pregnant saline (NS) rats. Results: The PAVP group showed significantly higher systolic and diastolic blood pressure than both saline-treated groups. The weight per pup was significantly lower in the AVP-treated group than in the saline group (p<0.05). Circulating TGF-β1-3 isomer levels were significantly higher in the PAVP rats than in the NS rats. However, similar TGF-β1 and TGF-β3 levels were noted in the PS and PAVP rats, while TGF-β2 levels were significantly higher in the PAVP rats. Circulating liver-type arginase-1 and 5'-nucleotidase levels were higher in the PAVP rats than in the saline group. Conclusion: This is the first study to demonstrate higher levels of TGF-β2, arginase, and 5'-nucleotidase activity in PAVP than in PS rats. AVP may cause vasoconstriction and increase peripheral resistance and blood pressure, thereby elevating TGF-β and inducing the preeclampsia-associated inflammatory response. Future studies should explore the mechanisms through which AVP dysregulates liver injury enzymes and TGF-β in pregnant rats.

A Study on the Productivity Improvement of Thermal Infrared Camera an Optical Lens (열적외선 카메라용 광학계 생산성 향상에 관한 연구)

  • Kim, Sung-Yong;Hyun, Dong-Hun
    • Journal of the Korean Society of Manufacturing Technology Engineers
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    • v.18 no.3
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    • pp.285-293
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    • 2009
  • Thermal infrared cameras have been conducted actively in various application areas, such as military, medical service, industries and cars. Because of their characteristic of sensing the radiant heat emitted from subjects in the range of long-wavelength($3{\sim}5{\mu}m$ or $8{\sim}12{\mu}m$), and of materializing a vision system, when general optics materials are used, they don't react to the light in the range of long-wavelength, and can't display their optic functions. Therefore, the materials with the feature of higher refractive index, reacting to the range of long-wavelength, are to be used. The kinds of materials with the characteristic of higher refractive index are limited, and their features are close to those of metals. Because of these metallic features, the existing producing method of optical systems were direct manufacturing method using grinding method or CAD/CAM, which put limit on productivity and made it difficult to properly cope with the increasing demand of markets. GASIR, a material, which can be molded easily, was selected among infrared ray optics materials in this study, and the optical system was designed with two Aspheric lenses. Because the lenses are molded in the environment of high temperature and high pressure, they require a special metallic pattern. The metallic pattern was produced with materials with ultra hardness that can stand high temperature and high pressure. As for the lens mold, GMP(Glass Molding Press) of the linear transfer method was used in order to improve the productivity of optical systems for thermal infrared cameras, which was the goal of this paper.

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Undergraduate Students' Degree of Request for the Eye-Health Education (대학생의 안보건교육 요구도)

  • Lee, Ok-Jin;Kim, Hye-Gum
    • Journal of Korean Ophthalmic Optics Society
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    • v.12 no.3
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    • pp.49-53
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    • 2007
  • In this paper, for the purpose of preparing some fundamental data on the development of the eye-health education program and conducting a practical application, the degree of request for the eye-health education were investigated by surveying 304 undergraduate students. The relationship between the degree of request for the eye-health education and sex, the division of major, and the experience of eye-health education was examined by SAS and $X^2$-test of questionnaire. The degree of request of undergraduate students for the eye-health education was as high as 86.51%. There was no statistical significant difference dependence on their experience of the eye-health education or their sex. There was significant difference dependence on their major. Specially, the degree of request of natural science, medical and health science majors was higher than any other majors. Consideration on the eye-health education should be required to meet the request of it.

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A Study on the Spherical Lens Manufacturing by Simultaneous 3-Axis for NC Lathe (NC 선반에서 동시 3축을 이용한 구면 렌즈 가공 연구)

  • Lee, Min-Ki;Lee, Eung-Suk;An, Dong-Youl
    • Proceedings of the KSME Conference
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    • 2004.11a
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    • pp.956-961
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    • 2004
  • This paper proposes a study on the spherical lens manufacturing by simultaneous 3 axis for NC lathe. We use friction drive system for moving system in experimental diamond turing machine. The diamond turning machine use manufacturing for high quality lens, mirror and many optics products. Especially, the high tech industry require a lot of lens. For example, optical engineering. medical science, space engineering and material engineering etc. The friction drive system is very simple and quiet, compared to ball screw system. We find a problem at the simultaneous 3 axis and suggest a solution. Also, when we manufactured a micro lens. find a problem and solution.

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Spherical arrangement of biomimetic polymer photonic structures (자연모사를 통한 미세 고분자 포토닉 구조의 구면배열에 관한 연구)

  • Jeong, Ki-Hun
    • Proceedings of the KSME Conference
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    • 2007.05a
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    • pp.403-404
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    • 2007
  • Compound eyes in nature present intriguing topics in physiological optics due to their unique optical scheme for imaging. For example, a bee's eye has thousands of integrated photonic units called ommatidia spherically arranged along a curvilinear surface so that each unit points in a different direction. The omni-directionally arranged ommatidium collects incident light with a narrow range of angular acceptance and independently contributes to the capability of wide field-of-view (FOV) detection. Artificial implementation of compound eyes has attracted a great deal of research interest because the wide FOV exhibits a huge potential for medical, industrial, and military applications. So far, imaging with a FOV over $90^{\circ}$ has been achieved only with fisheye lenses which rely on bulky and expensive multiple lenses and require stringent alignment. In this talk, we will discuss about the spherical 3D arrangement of the photonic structures of biologically inspired artificial compound eyes in a small form-factor to have and the functional and anatomical similiarity with natural compound eyes.

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