• Investigative Magnetic Resonance Imaging
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• v.25 no.4
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• pp.218-228
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• 2021

Due to their high degree of freedom to transfer and acquire light, fiber optics can be used in the presence of strong magnetic fields. Hence, optical sensing and imaging based on fiber optics can be integrated with magnetic resonance imaging (MRI) diagnostic systems to acquire valuable information on biological tissues and organs based on a magnetic field. In this article, we explored the combination of MRI and optical sensing/imaging techniques by classifying them into the following topics: 1) functional near-infrared spectroscopy with functional MRI for brain studies and brain disease diagnoses, 2) integration of fiber-optic molecular imaging and optogenetic stimulation with MRI, and 3) optical therapeutic applications with an MRI guidance system. Through these investigations, we believe that a combination of MRI and optical sensing/imaging techniques can be employed as both research methods for multidisciplinary studies and clinical diagnostic/therapeutic devices.

• Journal of Korean Ophthalmic Optics Society
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• v.12 no.3
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• pp.143-149
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• 2007

We have compared and analyzed the definition of medical devices, classification, who treats, controls and sales the spectacle frames in South Korea, USA and European Union in this paper. South Korea classifies the spectacle frames as an industrial products while EU and USA regards it them as the medical devices. Sunglasses are industrial products in South Korea and EU but they are still the medical devices in USA. Assignment of spectacle frames and sunglasses as an industrial products could bring into several problems. Restricted classification of medical devices on spectacle frames and sunglasses will resolve the problem mentioned.

• Journal of Korean Ophthalmic Optics Society
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• v.1 no.1
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• pp.41-51
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• 1996

According to Korean pharmaceutic law, spectacles is a kind of medical device or instrument that is composed of a front and two temples with a pair of lenses. If the spectacle is not worn, it is a kind of optical device, but if it were worn, it will makes a new optical system to correct ametropia. Therefore, spectacles must be carried on by dispensing opticians.

• Journal of Korean Ophthalmic Optics Society
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• v.12 no.4
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• pp.9-14
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• 2007

We have studied the problems associated with increasing number of ophthalmic optics students every year. The main problems are surplus supply of the optometrist and poor working condition. Thus all parties concerned who aim to solve the numerical unbalance of optometrist must have the common policy in sight. And we have to make a long-term plan and permanent organization for medical technician to establish supply and demand of medical technician with exact policy. To solve this unbalance of optometrist numbers, we have to establish an exact job category, reform the specialized education course, estimate the practical technique of national licensing examination for Korean optometrist, and innovate the contents and methods of reeducation.

• Proceedings of the KOSOMBE Conference
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• v.1991 no.05
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• pp.9-12
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• 1991

The correlation search method yields velocity information by tracking scatter patterns between medical image frames. The displacement vector between a target region and the best correlated search region indicates the magnitude and direction of the inter-frame motion of that particular region. However, if the noise sources in the target region and the search region are correlated Gaussian, then the cross-correlation technique fails to work well because it estimates the cross-correlation of both signals and noises. In this paper we develop a new correlation search method which seeks the best correlated third-order statistics between a target and the search region to suppress the effect of correlated Gaussian noise sources. Our new method yields better estimations of velocity than the conventional cross-correlation method.

• Current Optics and Photonics
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• v.6 no.6
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• pp.550-564
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• 2022

Optical microscopy is a useful tool for study in the biological sciences. With an optical microscope, we can observe the micro world of life such as tissues, cells, and proteins. A fluorescent dye or a fluorescent protein provides an opportunity to mark a specific target in the crowd of biological samples, so that an image of a specific target can be observed by an optical microscope. The optical microscope, however, is constrained in resolution due to diffraction limit. Super-resolution microscopy made a breakthrough with this diffraction limit. Using a super-resolution microscope, many biomolecules are observed beyond the diffraction limit in cells. In the case of volumetric imaging, the super-resolution techniques are only applied to a limited area due to long imaging time, multiple scattering of photons, and sample-induced aberration in deep tissue. In this article, we review recent advances in super-resolution microscopy for volumetric imaging. The super-resolution techniques have been integrated with various modalities, such as a line-scan confocal microscope, a spinning disk confocal microscope, a light sheet microscope, and point spread function engineering. Super-resolution microscopy combined with adaptive optics by compensating for wave distortions is a promising method for deep tissue imaging and biomedical applications.

• Current Optics and Photonics
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• v.6 no.2
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• pp.151-160
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• 2022

Fundus images can reflect ocular diseases and systemic diseases such as glaucoma, diabetes mellitus, and hypertension. Thus, research on fundus-detection equipment is of great importance. The fundus camera has been widely used as a kind of noninvasive detection equipment. Most existing devices can only obtain two-dimensional (2D) retinal-image information, yet the fundus of the human eye also has spectral characteristics. The fundus has many pigments, and their different distributions in the eye lead to dissimilar tissue penetration for light waves, which can reflect the corresponding fundus structure. To obtain more abundant information and improve the detection level of equipment, a snapshot nonmydriatic fundus imaging spectral system, including fundus-imaging spectrometer and illumination system, is studied in this paper. The system uses a microlens array to realize snapshot technology; information can be obtained from only a single exposure. The system does not need to dilate the pupil. Hence, the operation is simple, which reduces its influence on the detected object. The system works in the visible and near-infrared bands (550-800 nm), with a volume less than 400 mm × 120 mm × 75 mm and a spectral resolution better than 6 nm.

• Journal of the Optical Society of Korea
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• v.15 no.2
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• pp.111-117
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• 2011

Full-range spectral domain optical coherence tomography (SD-OCT) with a 1-${\mu}m$ band light source is shown here. The phase of the reference beam is continuously stepped while the probing beam scans the sample laterally (B-scan). The two dimensional spectral interferogram obtained is processed by a Fourier transform method to obtain a complex spectrum leading to a full-range OCT image. A detailed mathematical explanation of the complex conjugate resolving method utilized is provided. The system's measurement speed was 7.96 kHz, the measured axial resolution was $9.6{\mu}m$ in air and the maximum sensitivity 99.4 dB. To demonstrate the effect of mirror image elimination, In vivo human eye pathology was measured.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.26 no.8
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• pp.624-628
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• 2013

With the recent development of less-costly uncooled detector technology, expensive optics are among the remaining significant cost drivers in the thermography camera. As a potential solution to this problem, the fabrication of IR lenses using chalcogenide glass has been studied in recent years. We report on the molding and evaluation of a ultra-precision chalcogenide-glass lens for the thermography camera for body-temperature monitoring. In addition, we fabricated prototype thermography camera using the chalcogenide-glass lens and obtained the thermal image from the camera. In this work, it was found out that thermography camera discerned body-temperature between 20 and $50^{\circ}C$ through the analysis of thermal image. It is confirmed that thermography camera using the chalcogenide-glass lens is applicable to the body-temperature monitoring system.

• Current Optics and Photonics
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• v.5 no.4
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• pp.402-408
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• 2021

An off-axis system refers to an optical system in which the optical axis and normal vector at the vertex of each surface do not match. The most important specification in an optical system is its focal length. Among the various methods for measuring the focal length, the most suitable method for the off-axis system is the method that adopts magnification. However, head-mounted display (HMD) optics must be measured while considering the virtual image distance, which is not infinity owing to product characteristics. For the virtual image distance, a camera with a focusing function was used. By measuring HMD optics via this magnification method, the error generated in this measurement was 0.68% of the HMD's focal length, which is within the 1%-3% range of the conventionally permitted design error for the focal length allowed at the optical design stage. Therefore, it can be verified that the measurement accuracy of the method proposed in this study is sufficiently feasible in practice.