• IMMUNE NETWORK
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• v.23 no.4
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• pp.33.1-33.13
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• 2023

Vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been acknowledged as an effective mean of preventing infection and hospitalization. However, the emergence of highly transmissible SARS-CoV-2 variants of concern (VOCs) has led to substantial increase in infections among children and adolescents. Vaccine-induced immunity and longevity have not been well defined in this population. Therefore, we aimed to analyze humoral and cellular immune responses against ancestral and SARS-CoV-2 variants after two shots of the BNT162b2 vaccine in healthy adolescents. Although vaccination induced a robust increase of spike-specific binding Abs and neutralizing Abs against the ancestral and SARS-CoV-2 variants, the neutralizing activity against the Omicron variant was significantly low. On the contrary, vaccine-induced memory CD4⁺ T cells exhibited substantial responses against both ancestral and Omicron spike proteins. Notably, CD4⁺ T cell responses against both ancestral and Omicron strains were preserved at 3 months after two shots of the BNT162b2 vaccine without waning. Polyfunctionality of vaccine-induced memory T cells was also preserved in response to Omicron spike protein. The present findings characterize the protective immunity of vaccination for adolescents in the era of continuous emergence of variants/subvariants.

• International Journal of Advanced Culture Technology
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• v.5 no.2
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• pp.74-81
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• 2017

Recently, there are many companies that use systems based on artificial intelligence. The accuracy of artificial intelligence depends on the amount of learning data and the appropriate algorithm. However, it is not easy to obtain learning data with a large number of entity. Less data set have large generalization errors due to overfitting. In order to minimize this generalization error, this study proposed DGA(Dropout Genetic Algorithm) which can expect relatively high accuracy even though data with a less data set is applied to machine learning based genetic algorithm to deep learning based dropout. The idea of this paper is to determine the active state of the nodes. Using Gradient about loss function, A new fitness function is defined. Proposed Algorithm DGA is supplementing stochastic inconsistency about Dropout. Also DGA solved problem by the complexity of the fitness function and expression range of the model about Genetic Algorithm As a result of experiments using MNIST data proposed algorithm accuracy is 75.3%. Using only Dropout algorithm accuracy is 41.4%. It is shown that DGA is better than using only dropout.

• Journal of Korean Medical classics
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• v.18 no.2 s.29
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• pp.45-69
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• 2005

The condition contrary to the physiological conditions obtained by the normal functioning of seven constituents of the body is defined as disease. The primary causes of the disease are emotional defilements of desire, hatred and delusion. The secondary causes of diseases are seasonal climatic changes, the agency of harmful demons, and improper diet or conduct. Once a disease occurs, it brings the disfunctioning of the three humors of wind, bile, and phlegm. Therefore all the disease should be examined and determined which of theses three humors effect its nature the most. There are five main techniques of external therapy, namely bloodletting, which extract the impure blood produced by disease of heat; moxibustion, which debilitates cold diseases, medicinal compresses, fomentation, massage with ointment, and minor surgery. Among these, the former three are the mild treatment and the latter three the severe ones because of the pain the patient has to suffer during the whole procedure.

• The Journal of the Convergence on Culture Technology
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• v.1 no.4
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• pp.107-111
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• 2015

Humans must restore tired bodies and minds during sleep. Sleep as much as eating a meal many people looking for a hospital can not sleep, but a matter of course. The smart phone is loaded in the most recent studies it has been conducted to provide a service to the patient or medical personnel U-healthcare in the field of smart phone-based medical applications as with a variety of sensors, including an acceleration sensor. In this paper, the aim of providing an Android-based applications to use a variety of sensors incorporated in the popularity of smart phones to induce normal water flow to recognize the user's action.

• The Korean Journal of Emergency Medical Services
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• v.19 no.1
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• pp.35-49
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• 2015

Purpose: This study aimed to identify the current status and correlations among scuba divers' knowledge of safety, compliance with safety rules, and ability to cope with emergency situations. Methods: There were 317 study subjects. Data were collected between September 21, 2012 and September 7, 2013, and analyzed using SPSS software version 21.0. Results: Of the participants, 89.3% wanted to be educated in emergency care, while 69.4% indicated that preparedness in emergency situations for divers is insufficient. 78.5% suggested a need to creat a legal standard for the prevention of accidents. The average scores among the participants showed 3.22 points for knowledge of safety, 3.09 points for compliance with safety rules, and 2.91 points for ability to cope with accidents and emergency situations, with strong correlation among them. The lower license level they had, the lower score they indicated. Conclusion: We suggest there is a need to strengthen systematic educations on knowledge of safety, compliance with safety rules, and the ability to cope with emergency situations and emergency care at the open water level. In addition, there is a need to creat legal standards to consolidate the effects of these changes.

• The Korean Journal of Emergency Medical Services
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• v.13 no.3
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• pp.107-120
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• 2009

Purpose : The purpose of this study was to investigate the influence of organizational culture on job satisfaction of fire officials. Method : The subjects of this study were 251 fire officials in Gongju and Choengju province and Daejeon City. Data were collected using self-administering questionnaire from February 20 to March 20 in 2006. Collected data were analyzed using SPSS 14.0 program. Real number, percentage, mean and standard deviation were calculated, and t-test, ANOVA, Pearson correlation coefficient, multiple regression were analyzed. Result : The results of this study were as follows : 1. The job satisfaction was found to be significant positive correlations with full organizational culture(r = .595, p = .000). 2. The job satisfaction was found to be in significant positive with rational goal culture, open system culture and human relation culture. 3. How organizational culture affects the job satisfactions was as follows; 25.2% of core values of manpower, 6.3% of rational goal culture, and 4.9% of job initiative. Conclusion : Enhancing the job satisfaction of fire officials would improve personalized factors and changes rational goal culture.

• Quality Improvement in Health Care
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• v.25 no.1
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• pp.2-10
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• 2019

Purpose: The purpose of this study was to share program and/or resource on patient safety education for patients and families conducted overseas agency. This study will help the patient safety officer establish and implement an educational plan for patients and families. Methods: We searched the Internet for patient safety related organizations. We chose an institution that provided education for patients and families. Results: Most of the program and/or resource was about patient and family involvement; Taking Care of Myself, My Questions for This Visit, Patient Prep Card, 20 Tips to Help Prevent Medical Errors, Ask Me 3(R), Health and Safety Passport, My Medication log etc. Conclusions: It is necessary to distribute educational materials for patients and families in the country through the results of this study. For patient safety, education and publicity are needed so that developed educational materials can be actively used.

• The Korean Journal of Emergency Medical Services
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• v.23 no.1
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• pp.19-33
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• 2019

Purpose: The aim of this study was to provide basic data to aid in the effective adoption of the preceptor system for new paramedics by assessing the preceptor role awareness among senior 119 paramedics in the field. Methods: A questionnaire was administered to 182 senior paramedics who each had more than 3 years field experience. The questionnaire measuring preceptor role awareness was composed of 64 items with responses based on a 5 point Likert scale. Data were collected from July 31, 2018 to August 29, 2018, and were analyzed with IBM SPSS version 24.0. Results: The average score for preceptor role awareness was 3.87 (supervisor = 3.95, resource person = 3.88, role model = 3.85, and instruction designer = 3.81). There were significant differences in preceptor role awareness among the participants based on competence (p =.002) and clinical skill (p =.000). Also, there were high positive correlations between preceptor role awareness and its subdivision (p <.01). Conclusion: For effective operation of the preceptor system in the future, the preceptors' role as designers of instruction and role models should be enhanced, Also, future preceptors are very important in the improvement of competence and clinical skill in the preceptor system. Therefore, it is necessary to provide training that enables new preceptors to effectively adopt and operate the preceptor system.

• Safety and Health at Work
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• v.9 no.4
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• pp.447-453
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• 2018

Background: Patient safety and accurate implementation of medication orders are among the essential requirements of par nursing profession. In this regard, it is necessary to determine and prevent factors influencing medications errors. Although many studies have investigated this issue, the effects of psychosocial factors have not been examined thoroughly. Methods: The present study aimed at investigating the impact of psychosocial factors on nurses' medication errors by evaluating the balance between effort and reward. This cross-sectional descriptive study was conducted in public hospitals of Tehran in 2015. The population of this work consisted of 379 nurses. A multisection questionnaire was used for data collection. Results: In this research, 29% of participating nurses reported medication errors in 2015. Most frequent errors were related to wrong dosage, drug, and patient. There were significant relationships between medications errors and the stress of imbalance between effort and reward (p < 0.02) and job commitment and stress (p < 0.027). Conclusion: It seems that several factors play a role in the occurrence of medication errors, and psychosocial factors play a crucial and major role in this regard. Therefore, it is necessary to investigate these factors in more detail and take them into account in the hospital management.

• The Korean Journal of Emergency Medical Services
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• v.25 no.2
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• pp.169-186
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• 2021

Purpose: This study aimed to analyze the data from public information disclosure about pre-hospital advanced airway management and identify the problem by considering domestic laws and guidelines. Methods: Data were collected between 2017 and 2018 and analyzed using SPSS 25.0. Then, the problems of the analysis results based on the relevant laws and practical guidelines were reviewed. Results: The review of domestic laws and practice guidelines revealed that ambulance nurses can implement supraglottic airway device only under the following three conditions: ① smart advanced life support pilot project area, ② trained to insert I-Gel, and ③ member of a special ambulance. In total, 21,574 cases of advanced airway management (endotracheal intubation: 2,428, I-Gel: 18,502, LMA : 499, KING AIRWAY: 144) were reported. In many cases, advanced airway management was performed by ambulance nurses who did not meet the above conditions, which was in violation of laws and guidelines. In addition, the prognosis of intubated patients was not followed up. Conclusion: The Korea National Fire Agency must stop all unlicensed medical practice by untrained, uneducated, and uncertified nurses and demand quality control programs for intubated patients.