• ALGAE
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• 제26권4호
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• pp.343-350
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• 2011

Fermentation and enzyme-assisted extraction (EAE) improve nutritional and functional properties of foods by increasing the extraction of active compounds, ingestion rates, and body absorption. In this study, we investigated whether applying the EAE process improves the extraction and isolation efficiency of a polysaccharide from fermented Ecklonia cava (FE), which inhibited NO production in lipopolysaccharide (LPS)-activated RAW 264.7 cells. The results showed that the FE using the fungi Candida utilis and two different bacteria, namely Lactobacillus brevis and Saccharomyces cerevisiae increased protein and carbohydrate contents in comparison with those in non-fermented E. cava (NE). Aqueous extracts of fermented E. cava increased extraction yields and carbohydrate content, compared with the aqueous extract of NE. In addition, treating LPS-stimulated RAW 264.7 cells with aqueous extracts resulted in reduced NO production compared to that in LPS-treated cells. Ten EAEs of L. brevis-fermented E. cava (LFE) improved NO inhibitory effects in LPS-activated RAW 264.7 cells and the Viscozyme extract (VLFE) from the resulting extracts showed the highest NO inhibitory effect. We found that the >30 kDa fraction of VLFE led to markedly high inhibition of LPS-induced NO production as compared to that in the <30 kDa fraction. The crude polysaccharide isolated from >30 kDa fraction (VLFEP) consisted of fucose and markedly decreased NO production induced by LPS stimulation. VLFEP could be useful as an anti-inflammatory agent to suppress macrophage activation.

• 한국해양환경ㆍ에너지학회지
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• 제6권3호
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• pp.3-15
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• 2003

청정생산의 개념과 현재 육상의 산업활동과 연계되어 연구 개발되고 있는 청정생산 기술동향을 살펴보고, 이들이 해양산업영역으로의 응용성을 검토하였다. 기존의 해양오염 정화활동은 새로운 청정생산체제의 영역으로 자연스럽게 흡수될 수 있지만 지속가능한 발전이라는 명제 아래서 해양의 생산과 환경활동을 재조명할 필요가 있다. 청정생산의 시작이라 할 수 있는 재생가능 에너지의 개발은 해양자원 활용의 한 영역이며 육상과 대기 그리고 해양을 묶는 산업생태의 청정 에너지원을 해양이 공급할 가능성도 있다 청정생산체제를 해양산업에 조속하고 성공적으로 도입하기 위하여 여론수렴, 환경감시, 문제점 분석 및 개선방향 도출, 신기술/신정책의 평가 및 적용, 정보공유, 교육 및 홍보 등의 실천이 수행되어야 한다. 이를 위하여 한국해양환경공학회 중심의 정부 민간 중간 단계의 기구 설치를 제안한다.

• 한국CDE학회논문집
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• 제16권1호
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• pp.41-51
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• 2011

Both enterprise information systems and CAD utilizes the BOM (Bill of Material) as the means of collaborative integration during the product design and production since the BOM has been commonly used for design, production planning, procurement, and production works. Therefore, BOM can be the referential data when it expresses not only the part lists but also product information required by product development process. Outfitting design is one of major design works in marine vessel design since marine vessels have various outfitting systems and huge number of parts. Also, the outfitting BOM has the evolutional forms that change from the initial design to the production design. In order to express the product information and part list in the enterprise BOM and the evolutional BOMs in each lifecycle, enterprise BOM of outfitting that consists of structure BOM and display BOM is suggested. Thereafter, we have developed the prototype of enterprise BOM in which some features of the outfitting BOM are implemented.

• 한국해양바이오학회지
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• 제4권1호
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• pp.6-10
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• 2010

Indonesia is well-known as biggest producer of seaweed especially for Eucheuma and Gracilaria and also has huge potential resources and capability to develop seaweed cultivation and product. There are several provinces which have potential resources and have been contributing on seaweed production. The next challenge about seaweed production is using integrated system on brackishwater and marine aquaculture. Furthermore, about 2,000,000 ton of potential seaweed production is not explored yet. This article also tries to figure out some related aspects which are technical, economical and forecasting aspect. There is a disease which named "ice-ice" is one of the main problem and giving a new challenge in developing of problem solving for seaweed cultivation method. Economical parameters are also main important key to find out the feasibility of seaweed cultivation industry. In addition, the seaweed cultivation and production in Indonesia also have potential performance on biofuel resources as a part for solving the world problem on energy demand.

• Biomolecules & Therapeutics
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• 제24권6호
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• pp.561-571
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• 2016

Marine biosphere is the largest one of the earth and harbors an enormous number of different organisms. Living conditions differ fundamentally from those in terrestrial environment. The production of specific secondary metabolites is an important adaption mechanism of marine organisms to survive in the sea. These metabolites possess biological activities which make them interesting as possible drugs for human. The review presents sources, chemistry, production and pharmacology of FDA approved marine derived pharmaceuticals arranged according to their therapeutic indication. Four of the presently seven approved drugs are used for the treatment of cancer. Each another one is applicated for treatment of viral diseases, chronic pain and to lower triglyceride level in blood. Some other products are of interest in diagnostic and as experimental tools. Besides, this article describes challenges in drug development from marine sources, especially the supply problem.

• Fisheries and Aquatic Sciences
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• 제8권3호
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• pp.177-181
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• 2005

Fishing selectivity is determined by the level of voluntary escaping behavior in accordance with decision-making based on the relationship between fish size and mesh size. This study examined movement during the swimming behavior of black porgy in a trawl's towing cod-end and analyzed the movement components such as swimming speed, angular velocity of turning, and distance to the net over time. Most of the observed fish exhibited an optomotor response, maintaining position and swimming speed without changing direction. Others exhibited erratic or 'panic' behavior with sudden changes in swimming speed and direction. The latter behavior involved very irregular and aperiodic variations in swimming speed and angular velocity, termed 'chaotic behavior.' Thus, the results of this study can be applied to a chaotic behavior model as a time series of swimming movements in the towing cod-end for the fishing selectivity.

• 한국항해항만학회지
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• 제30권4호
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• pp.303-308
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• 2006

This study is designed to analyze the production, employment, value added and income impacts tha, in the event of designation and development of Haeundae as 'Convention, Movie, Marine Leisure Special Zone', its marine sector would have on the local economy. The realization of marine leisure special zone of Haeundae in Busan is expected to lead to a direct and indirect investment of approx. \13.6 billion, resulting in \68.0 billion in production impact, 850 jobs in employment impact, \28.0 billion in value added impact and \14.5 billion in income impact. This is expected to give a boost to a stagnant local economy, offering opportunities for the revival of Busan's tourist industry.

• 한국항해항만학회지
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• 제36권2호
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• pp.131-140
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• 2012

Since 2000, S. Korea is building yachts through government supported localization, cooperation between industry and educational organizations, or partnerships with foreign firms but the yacht building has yet only accomplished trial manufactured ships and one-time production. Because of a lack of mass production, the industry assesses the domestic technical skills to an average 50~60% of developed countries and its market share is less than 1% in the world. In addition, domestic marine equipment is heavily depending on imports and the industry is experiencing shortage of technology and experts, small-sized companies, insufficient industry and educational organizations' cooperation networks, inadequate legislation and policies, deficient domestic market vitalization, and scarce international information. Thus, this study focuses on the alternative plans to strengthen competitiveness and to cope with problems in the southeast marine leisure equipment industry.

• 한국해양바이오학회지
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• 제15권1호
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• pp.1-11
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• 2023

In the present study, the antioxidant and anti-inflammatory activities of ethanolic extracts from Lathyrus japonicus at concentrations of 50, 100, and 200 ㎍/mL were investigated in LPS-stimulated, RAW264.7 cells. Antioxidant properties were determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging assays and ferric reducing antioxidant power assay. In addition, the production of reactive oxygen species (ROS) was measured using the 2',7'-dichlorofluorescein diacetate (DCFH-DA) probe by flow cytometry. To examine the anti-inflammatory activity of the extracts of L. japonicus, their effects on the levels of nitric oxide (NO); production of cytokines such as interleukin (IL)-1β, IL-10, and tumor necrosis factor-α (TNF-α); and the activities of enzymes such as inducible NOS (iNOS) and cyclooxygenase-2 (COX-2) were assessed. The IC₅₀ values of the DPPH and ABTS radical scavenging assays were 476.09 ± 1.50 and 34.91 ± 0.37 ㎍/mL, respectively. In addition, L. japonicus extracts not only inhibited ROS production, but also the production of NO, IL-1β, and IL-10, and the activity of iNOS in a dose-dependent manner. In summary, the ethanolic extracts of L. japonicus could be used as a functional food additive and an anti-inflammatory agent owing to their antioxidant and anti-inflammatory activities

• 한국수산학회:학술대회논문집
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• 한국수산학회 2005년도 춘계학술대회
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• pp.161-161
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• 2005