• Title/Summary/Keyword: MSK1

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Medullary Sponge Kidney Detected in the Pediatric Age (소아 연령에서 발견된 medullary sponge kidney)

  • Chung, Woo Yeong;Cho, Min Hyun;Gu, Young-Ran;Leem, Sun-Hee;Cheong, Hae Il
    • Childhood Kidney Diseases
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    • v.16 no.2
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    • pp.109-114
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    • 2012
  • Purpose: Medullary sponge kidney (MSK) is a rare congenital disease characterized by diffuse ectasia or dilatation of precalyceal collecting tubules. MSK incidence and prevalence in the general population is uncertain and only a few patients are reported especially in the pediatric age. There has been increasing reports of patients with MSK who have other malformative disorders. Also several case reports concerning about etiological association of some genes. Methods: Collaborative study through nation-wide survey was done to investigate the incidence and etiological association of some genes such as GDNF gene, ATP6V1B1, ATP6V0A4 gene in developing MSK in Korean children. Results: Four cases of MSK who have various other malformative disorders were collected. There are no mutations of GDNF gene, ATP6V1B1, ATP6V0A4 gene in all patients. Conclusion: MSK is one of the very rare diseases in pediatric age. The etiological association of GDNF gene, ATP6V1B1, ATP6V0A4 gene in developing MSK in Korean children is not proved.

Efficiently Hybrid $MSK_k$ Method for Multiplication in $GF(2^n)$ ($GF(2^n)$ 곱셈을 위한 효율적인 $MSK_k$ 혼합 방법)

  • Ji, Sung-Yeon;Chang, Nam-Su;Kim, Chang-Han;Lim, Jong-In
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.44 no.9
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    • pp.1-9
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    • 2007
  • For an efficient implementation of cryptosystems based on arithmetic in a finite field $GF(2^n)$, their hardware implementation is an important research topic. To construct a multiplier with low area complexity, the divide-and-conquer technique such as the original Karatsuba-Ofman method and multi-segment Karatsuba methods is a useful method. Leone proposed an efficient parallel multiplier with low area complexity, and Ernst at al. proposed a multiplier of a multi-segment Karatsuba method. In [1], the authors proposed new $MSK_5$ and $MSK_7$ methods with low area complexity to improve Ernst's method. In [3], the authors proposed a method which combines $MSK_2$ and $MSK_3$. In this paper we propose an efficient multiplication method by combining $MSK_2,\;MSK_3\;and\;MSK_5$ together. The proposed method reduces $116{\cdot}3^l$ gates and $2T_X$ time delay compared with Gather's method at the degree $25{\cdot}2^l-2^l with l>0.

Casein Kinase 2 interacts with human mitogen- and stress-activated protein kinase MSK1 and phosphorylates it at Multiple sites

  • Shi, Yan;Han, Guanghui;Wu, Huiling;Ye, Kan;Tian, Zhipeng;Wang, Jiaqi;Shi, Huili;Ye, Mingliang;Zou, Hanfa;Huo, Keke
    • BMB Reports
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    • v.42 no.12
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    • pp.840-845
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    • 2009
  • Mitogen- and stress-activated protein kinase (MSK1) palys a crucial role in the regulation of transcription downstream of extracellular-signal-regulated kinase1/2 (ERK1/2) and mitogen-activated protein kinase p38. MSK1 can be phosphorylated and activated in cells by both ERK1/2 and p38$\alpha$. In this study, Casein Kinase 2 (CK2) was identified as a binding and regulatory partner for MSK1. Using the yeast two-hybrid system, MSK1 was found to interact with the CK2$\beta$ regulatory subunit of CK2. Interactions between MSK1 and the CK2$\alpha$ catalytic subunit and CK2$\beta$ subunit were demonstrated in vitro and in vivo. We further found that CK2$\alpha$ can only interact with the C-terminal kinase domain of MSK1. Using site-directed mutagenesis assay and mass spectrometry, we identified five sites in the MSK1 C-terminus that could be phosphorylated by CK2 in vitro: Ser757, Ser758, Ser759, Ser760 and Thr793. Of these, Ser757, Ser759, Ser760 and Thr793 were previously unknown.

Double Duobinary MSK Modeling of the SOQPSK-TG Signal (SOQPSK-TG 신호의 이중 듀오바이너리 MSK 모델링)

  • Kim, KyunHoi;Eun, Changsoo
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.49 no.11
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    • pp.945-951
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    • 2021
  • The SOQPSK-TG is a modulated signal for aeronautical telemetry with a very good bandwidth efficiency. In this paper, the frequency waveform filter of the SOQPSK-TG is linearly approximated and modeled with a duobinary precoder and a modified frequency waveform filter having a phase transition period of about 1Tb. In combination with the existing precoder, the SOQPSK-TG is modeled by a double duobinary MSK. Comparing the SOQPSK-TG signal and the newly modeled double duobinary MSK signal in time domain and frequency domain, it is confirmed that the two signals are almost identical and there is virtually no performance difference. Moreover, we can attain 0.1 dB BER performance improvement compared to the existing cosine filter when the filter of the IQ-detector is implemented with a cosine sum filter taking into account the change in the modulation index by the new double doubinary precoder.

Multi-Tone Anti-Jamming Performance Analyses of MSK & QPSK Modulation Hybrid DS-SFH Spread-Spectrum System (MSK와 QPSK 변조 DS-SFH 확산시스템의 다중톤 항재밍 성능 분석)

  • Kim, Yun-Yeong;Yu, Heung-Gyun;Kim, Gi-Geun;Choe, Yeong-Gyun
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.37 no.8
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    • pp.1-10
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    • 2000
  • Performance analyses of hybrid DS-SFH spread-spectrum systems using coherent MSK and QPSK modulation techniques are considered over Rayleigh fading channel in the presence of multi-tone jamming. The BER equations for MSK and QPSK systems with non-diversity reception in the receiver are derived as the concept of average signal-to-noise power ratio E$\_$b//N$\_$0/ and jamming-to-signal power ratio JSR, and the performances is evaluated for various system parameters. The evaluation of performance is done between fading and nonfading system, and between MSK and QPSK system. Results show that the performances of two systems are similar in low JSR. However, MSK system outperforms QPSK system as JSR increases. Overall performances of two systems are a little improved as the DS spreading gain increases for the total spread-spectrum bandwidth fixed. The performance difference between fading system and nonfading system is similar in low E$\_$b//N$\_$0/, however, it becomes very largewith increase of E$\_$b//N$\_$0/..

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Mathematical Analysis Power Spectrum of M-ary MSK and Detection with Optimum Maximum Likelihood

  • Niu, Zheng;Jiang, Yuzhong;Jia, Shuyang;Huang, Zhi;Zou, Wenliang;Liu, Gang;Li, Yu
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.15 no.8
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    • pp.2900-2922
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    • 2021
  • In this paper, the power spectral density(PSD) for Multilevel Minimum Shift Keyed signal with modulation index h = 1/2 (M-ary MSK) are derived using the mathematical method of the Markov Chain model. At first, according to an essential requirement of the phase continuity characteristics of MSK signals, a complete model of the whole process of signal generation is built. Then, the derivations for autocorrelation functions are carried out precisely. After that, we verified the correctness and accuracy of the theoretical derivation by comparing the derived results with numerical simulations using MATLAB. We also divided the spectrum into four components according to the derivation. By analyzing these figures in the graphic, each component determines the characteristics of the spectrum. It is vital for enhanced spectral characteristics. To more visually represent the energy concentration of the main flap and the roll-down speed of the side flap, the specific out-of-band power of M-ary MSK is given. OMLCD(Optimum Maximum Likelihood Coherent Detection) of M-ary MSK is adopted to compare the signal received with prepared in advance in a code element T to go for the best. And M-ary MSK BER(Bit Error Rate) is compared with the same ary PSK (Phase Shift Keying) with M=2,4,6,8. The results show the detection method could improve performance by increasing the length of L(memory inherent) in the phase continuity.

Matrix-Star Graphs : A New Interconnection Network Based on Matrix Operation (행렬-스타그래프 : 행렬연산에 기반한 새로운 상호 연결망)

  • Lee, Hyeong-Ok;Im, Hyeong-Seok
    • Journal of KIISE:Computer Systems and Theory
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    • v.26 no.4
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    • pp.389-405
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    • 1999
  • 본 논문에서는 상호 연결망의 노드를 행렬로 표현하고 행렬연산을 이용하여 에지를 정의한 새로운 상호 연결망으로 행렬-스타 그래프를 제안한다. 행렬-스타 그래프는 널리 알려진 스타 그래프를 일반화한 그래프이다. 먼저, 행렬-스타 그래프의 노드를 2 $\times$ n 행렬로 표현한 행렬-스타 그래프 MS2,n 에 대하여 주요 망 척도인 분지수, 연결도, 확장성, 대칭성, 리우팅 ,지름 방송등을 분석한다. 다음으로, 행렬-스타 그래프 MS2,n의 노드를 2차원과 3차원으로 일반화한 행렬-스타 그래크 MSk,n과 MS k,n,p를 정의하고 행렬-스타그래프 MSk,n,p 의 라우팅 알고리즘과 지름을 분석한다. 상호연결망의 중요 망 척도중 하나는 망 비용이고 상호연결망의 망 비용은 그 연결망의 분지수와 지름의 곱으로 정의된다. star 그래프는 다른 상호 연결망보다 작은 망 비용을 갖는다. 최근에 제안된 Macro-Star 그래픈 star 그래프에 비해 상대적으로 망 비용이 작은 값을 갖는 연결망이다. (n2)!개의 노드를 갖는 행렬-스타 그래프 MSk,k,k(k={{{{ `^{ 3} SQRT { n$^2$} }}}} )와 ((n-1)2 + 1)!개의 노드를 갖는 Macro-Star 그래프 MS(n-1, n-1)의 망 비용은 행렬-스타그래프 MSk,k,k(k={{{{ `^{ 3} SQRT { n$^2$} }}}})는 O(n2,7)이고, Macro-Star 그래프 MS(n-1 , n-1)은 O(n3) 이다. 이는 행렬-스타 그래프가 스타 그래프와 Macro-Star 그래프보다 망비용이 우수함을 의미한다.

Performacne of Bandwidth Efficient QORC Modulation (효율적인 대역폭을 갖는 QORC 변조의 성능)

  • 인웅식;박상규
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.14 no.3
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    • pp.240-248
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    • 1989
  • In this paper, We analyse the Performance of Bandwidth efficient QORC modulation signal transmission through the presence of Additive White Gaussian noise. As a receiver, the QPSK receiver with Coherent demodultor is employed. The Sampling time for QORC Signal detection is [(2n-1)T, (2n+1)T] for decision of QORC Singla. It is abtained that the bandwidth of QORC is one half that of MSK, and QORC requires more power than QPSK by 1dB at a low error rate.

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Effects of Partial-band Noise Interference on the Performance of Hybrid Ds/SFH-MSK Spectrum System in Rayleigh Fading Channel (Rayleigh Fading 채널에서 DS/SFH-MSK 시스템의 성능에 대한 부분대역 잡음 간섭의 특성)

  • 김윤영;안병록;유흥균
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.12 no.2
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    • pp.251-256
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    • 2001
  • An error probability analysis is performed far a hybrid DS/SFH spread-spectrum system using minimum shift keying(MSK) modulation. The channel is assumed to be a Rayleigh fading channel with partial-band noise interference. Expressions are derived for the bit error rate(BER) in the context of Rician and Rayleigh fading channels, as a function of the average signal-to-noise ratio(SNR) $E_b/N_0$, the average signal-to- interference ratio(SJR) $E_b/N_J$, and channel parameters. As a result, in the fading channel with large Rician factor, K, which denotes the ratio of power of the direct and the diffused components, the partial-band interference is the worst case. On the other hand, in Rayleigh fading channel(K=0), the full-band interference($\rho$=1) brings the system to the worst case. Performance comparisons among various channels show that the factor K has much large effect on overall performance. For example, in conditions of $\rho$=0.1 and BER=$10^-2$, the system in Rician channel with K=10 requires more 1.9 dB SNR than that in AWGN channel, whereas it is less 5 dB SNR than that in the Rayleigh channel with K=0.

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Effects of PSK Modulation Methods in Underwater Acoustic Communication (PSK 변조방식이 수중통신에 미치는 영향에 관한 연구)

  • Cho, Jin-Soo;Jung, Seung-Back;Shim, Tae-Bo
    • The Journal of the Acoustical Society of Korea
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    • v.26 no.7
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    • pp.366-374
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    • 2007
  • In underwater wireless communication, needs for long distance communication using the high frequency are surpassing ones of short range communication by ultrasonic wave, and demands for transmitting and receiving various data such as voice or high resolution image data are increasing as well. In this work, we studied the effects on the real underwater communication depending on the difference of digital modulation methods. Simulation shows that only the performance of GMSK among many other PSK based modulation schemes(BPSK, QPSK, MSK, GMSK) is significant. Test condition simulates the oceanographic conditions along the 207-survey line, 15Km south of Busan and SNR is maintained 35dB or below. Simulated tests are composed of both transmitting image data($3{\times}10^5$ pixel, 4 bit per pixel) and voice communication($10^{-2}$BER, channel capacity of 1Kbps). Test results show that there are gain of about 7 seconds in transmission time in image transmission case, where channel capacity for BPSK, QPSK, and MSK and for GMSK were 65 Kbps and 45 Kbps, respectively and gain of about 8Km in distances in voice communication case.