• Title/Summary/Keyword: MAP1B

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Effects of Aloe and Violae herba Extract on the Anti-oxidant, Anti-inflammatory, Anti-wrinkle and Whitening (노회(蘆薈)(알로에), 자화지정(紫花地丁)의 항산화, 항염증, 주름, 미백에 미치는 영향)

  • Kim, Chang-Hun;Jung, Hyeon-A;Roh, Seok-Sun;Hong, Seok-Hoon
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.23 no.1
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    • pp.23-43
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    • 2010
  • Objective : This study was performed to assess the effects of Aloe and Violae herba extracts on skin disease and skin beauty. Methods : Anti-oxidant effects were measured by the scavenging for DPPH radical, xanthine oxidase activity. Anti-inflammatory effects were examined by relations in NO synthesis, IL-$1{\beta}$, IL-6, TNF-$\alpha$, NF-kB, COX-2, MAP kinase. The skin wrinkle formation effects were measured by collagenase and elastase activities. The whitening effects were examined by tyrosinase activities, melanin synthesis in MNT-1 cell. Results : 1. In an anti-oxidant test, Aloe and Violae herba extracts showed high radical scavenging activity. 2. In an anti-inflammatory test, Aloe and Violae herba extracts strongly inhibited the lipopolysaccharide(LPS)-induced nitric oxide(NO) release from the RAW 246.7 macrophage cells. Aloe and Violae herba extracts also inhibited the LPS-induced IL-$1{\beta}$ and COX-2 expressions. The inhibitory effects of Aloe and Violae herba extracts on macrophage activation were via the inhibition of NF-kB, evidenced by transient transfection assay. Furthermore, Aloe and Violae herba extracts weakly inhibited the activation of Jun-N-terminal kinase(JNK) but they did not have any effects on p38 MAP kinase in RAW 264.7 cells. 3. In the skin wrinkle formation assay, Aloe extract strongly inhibited collagenase and elastase, whose activity are tightly related with the wrinkle formation. 4. In the skin whitening assay, Aloe and Viloae herba extracts weakly inhibited tyrosinase activity, however, it was not statistically significant. Besides they did not have any effects on melanin synthesis, indicating that they could not be applicable for skin whitening. Conclusion : This study show that Aloe and Violae herba extracts may play a significant role in skin disease and skin beauty.

Disparity Estimation for Intermediate View Reconstruction of Multi-view Video (다시점 동영상의 중간시점영상 생성을 위한 변이 예측 기법)

  • Choi, Mi-Nam;Yun, Jung-Hwan;Yoo, Ji-Sang
    • Journal of Broadcast Engineering
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    • v.13 no.6
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    • pp.915-929
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    • 2008
  • In this paper, we propose an algorithm for pixel-based disparity estimation with reliability in the multi-view image. The proposed method estimates an initial disparity map using edge information of an image, and the initial disparity map is used for reducing the search range to estimate the disparity efficiently. Furthermore, disparity-mismatch on object boundaries and textureless-regions get reduced by adaptive block size. We generated intermediate-view images to evaluate the estimated disparity. Test results show that the proposed algorithm obtained $0.1{\sim}1.2dB$ enhanced PSNR(peak signal to noise ratio) compared to conventional block-based and pixel-based disparity estimation methods.

Changes in expression of the autophagy-related genes microtubule-associated protein 1 light chain 3β and autophagy related 7 in skeletal muscle of fattening Japanese Black cattle: a pilot study

  • Nakanishi, Tomonori;Tokunaga, Tadaaki;Ishida, Takafumi;Kobayashi, Ikuo;Katahama, Yuta;Yano, Azusa;Erickson, Laurie;Kawahara, Satoshi
    • Asian-Australasian Journal of Animal Sciences
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    • v.32 no.4
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    • pp.592-598
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    • 2019
  • Objective: Autophagy is a bulk degradation system for intracellular proteins which contributes to skeletal muscle homeostasis, according to previous studies in humans and rodents. However, there is a lack of information on the physiological role of autophagy in the skeletal muscle of meat animals. This study was planned as a pilot study to investigate changes in expression of two major autophagy-related genes, microtubule-associated protein 1 light chain $3{\beta}$ (MAP1LC3B) and autophagy related 7 (ATG7) in fattening beef cattle, and to compare them with skeletal muscle growth. Methods: Six castrated Japanese Black cattle (initial body weight: $503{\pm}20kg$) were enrolled in this study and fattened for 7 months. Three skeletal muscles, M. longissimus, M. gluteus medius, and M. semimembranosus, were collected by needle biopsy three times during the observation period, and mRNA levels of MAP1LC3B and ATG7 were determined by quantitative reverse-transcription polymerase chain reaction. The expression levels of genes associated with the ubiquitin-proteasome system, another proteolytic mechanism, were also analyzed for comparison with autophagy-related genes. In addition, ultrasonic scanning was repeatedly performed to measure M. longissimus area as an index of muscle growth. Results: Our results showed that both MAP1LC3B and ATG7 expression increased over the observation period in all three skeletal muscles. Interestingly, the increase in expression of these two genes in M. longissimus was highly correlated with ultrasonic M. longissimus area and body weight. On the other hand, the expression of genes associated with the ubiquitin-proteasome system was unchanged during the same period. Conclusion: These findings suggest that autophagy plays an important role in the growth of skeletal muscle of fattening beef cattle and imply that autophagic activity affects meat productivity.

A study on the implementation of MMS in Mini-MAP (Mini-MAP에서의 MMS 구현에 관한 연구)

  • Kim, H.;Kang, M. S.;Park, M.;Lee, S. B.;Kong, H. T.;Choi, M. S.
    • 제어로봇시스템학회:학술대회논문집
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    • 1990.10a
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    • pp.745-748
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    • 1990
  • MMS (Manufacturing Message Specification) is a communications standard of MAP (Manufacturing Automation Protocol), which is a Network Protocol for Industrial Automation. In the environment of Mini-MAP, MMS is situated in the application layer and on the LLC (Logical Link Control) layer. In this paper, MMS software is implemented on the basis of ISO DIS 9506. The implemented software was tested with Token Passing Bus Network Interface Unit, which was designed in our laboratory and performs the actions of layer 1 and 2.

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Map-Based Control for Autonomous Tractors

  • Han, S.;Shin, B.S.;Zhang, Q.
    • Agricultural and Biosystems Engineering
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    • v.4 no.1
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    • pp.22-27
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    • 2003
  • An autonomous tractor requires not only automatic steering (automatic guidance) but also automated control of tractor functions and implement operations. Examples of tractor functions include engine throttle, transmission speed, and 3-point hitch position. Implement operations include tillage, planting, and cultivating. This article provides an overview of a map-based methodology used for the implementation of autonomous field operations of agricultural tractors. The procedure for developing autonomous field operation maps were presented, and several important issues in the implementation of map-based autonomous operations were discussed. These issues included combining field operation maps, position offset, and real-time sensing and update of field operation maps.

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A method of describing and retrieving a sequence of moving object using Shape Variation Map (모양 변화 축적도를 이용한 움직이는 객체의 표현 및 검색 방법)

  • Choi, Min-Seok;Kim, Whoi-Yul
    • The KIPS Transactions:PartB
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    • v.11B no.1
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    • pp.1-6
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    • 2004
  • Motion Information in a video clip often plays an important role in characterizing the content of the clip. A number of methods have been developed to analyze and retrieve video contents using motion information. However, most of these methods focused more on the analysis of direction or trajectory of motion but less on the analysis of the movement of an object. In this paper, we introduce the shape variation descriptor for describing shape variation caused by object movement along time, and propose a method to describe and retrieve the shape variation of the object using shape variation map. The experimental results shows that the proposed method performed much better than the previous method by l1% and is very effective for describing the shape variation which is applicable to semantic retrieval applications.

A Comparison Study of Volumetric Modulated Arc Therapy Quality Assurances Using Portal Dosimetry and MapCHECK 2

  • Jin, Hosang;Jesseph, Fredrick B.;Ahmad, Salahuddin
    • Progress in Medical Physics
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    • v.25 no.2
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    • pp.65-71
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    • 2014
  • A Varian Portal Dosimetry system was compared to an isocentrically mounted MapCHECK 2 diode array for volumetric modulated arc therapy (VMAT) QA. A Varian TrueBeam STx with an aS-1000 digital imaging panel was used to acquire VMAT QA images for 13 plans using four photon energies (6, 8, 10 and 15 MV). The EPID-based QA images were compared to the Portal Dose Image Prediction calculated in the Varian Eclipse treatment planning system (TPS). An isocentrically mounted Sun Nuclear MapCHECK 2 diode array with 5 cm water-equivalent buildup was also used for the VMAT QAs and the measurements were compared to a composite dose plane from the Eclipse TPS. A ${\gamma}$ test was implemented in the Sun Nuclear Patient software with 10% threshold and absolute comparison at 1%/1 mm (dose difference/distance-to-agreement), 2%/2 mm, and 3%/3 mm criteria for both QA methods. The two-tailed paired Student's t-test was employed to analyze the statistical significance at 95% confidence level. The average ${\gamma}$ passing rates were greater than 95% at 3%/3 mm using both methods for all four energies. The differences in the average passing rates between the two methods were within 1.7% and 1.6% of each other when analyzed at 2%/2 mm and 3%/3 mm, respectively. The EPID passing rates were somewhat better than the MapCHECK 2 when analyzed at 1%/1 mm; the difference was lower for 8 MV and 10 MV. However, the differences were not statistically significant for all criteria and energies (p-values >0.05). The EPID-based QA showed large off-axis over-response and dependence of ${\gamma}$ passing rate on energy, while the MapCHECK 2 was susceptible to the MLC tongue-and-groove effect. The two fluence-based QA techniques can be an alternative tool of VMAT QA to each other, if the limitations of each QA method (mechanical sag, detector response, and detector alignment) are carefully considered.

ISOMORPHISMS OF CERTAIN TRIDIAGONAL ALGEBRAS

  • Choi, Taeg-Young;Kim, Si-Ju
    • The Pure and Applied Mathematics
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    • v.7 no.1
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    • pp.49-60
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    • 2000
  • We will characterize isomorphisms from the adjoint of a certain tridiag-onal algebra $AlgL_{2n}$ onto $AlgL_{2n}$. In this paper the following are proved: A map $\Phi{\;}:{\;}(AlgL_{2n})^{*}{\;}{\longrightarrow}{\;}AlgL_{2n}$ is an isomorphism if and only if there exists an operator S in $AlgL_{2n}$ with all diagonal entries are 1 and an invertible backward diagonal operator B such that ${\Phi}(A){\;}={\;}SBAB^{-1}S^{-1}$.

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PRETOPOLOGICAL CONVERGENCE QUOTIENT MAPS

  • Park, Sang-Ho
    • The Pure and Applied Mathematics
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    • v.3 no.1
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    • pp.33-40
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    • 1996
  • A convergence structure defined by Kent [4] is a correspondence between the filters on a given set X and the subsets of X which specifies which filters converge to points of X. This concept is defined to include types of convergence which are more general than that defined by specifying a topology on X. Thus, a convergence structure may be regarded as a generalization of a topology. With a given convergence structure q on a set X, Kent [4] introduced associated convergence structures which are called a topological modification and a pretopological modification. (omitted)

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A relative root Nielsen number

  • Yang, Ki-Yeol
    • Communications of the Korean Mathematical Society
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    • v.11 no.1
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    • pp.245-252
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    • 1996
  • The relative Nielsen number N(f;X,A) was introduced in 1986. It gives us a better, and ideally sharp, lower bound for the minimum number MF[f;X,A] of fixed points in the homotopy class of the map $f;(X,A) \to (X,A)$. Similarly, we also can think about the Nielsen map $f:(X,A) \to (X,A)$. Similarly, we also can be think about the Nielsen root theory. In this paper, we introduce a relative root Nielsen number N(f;X,A,c) of $f:(X,A) \to (Y,B)$ and show some basic properties.

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