• Title/Summary/Keyword: M30

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Plasma Soluble CD30 as a Possible Marker of Adult T-cell Leukemia in HTLV-1 Carriers: a Nested Case-Control Study

  • Takemoto, Shigeki;Iwanaga, Masako;Sagara, Yasuko;Watanabe, Toshiki
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.18
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    • pp.8253-8258
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    • 2016
  • Elevated levels of soluble CD30 (sCD30) are linked with various T-cell neoplasms. However, the relationship between sCD30 levels and the development of adult T-cell leukemia (ATL) in human T-cell leukemia virus type 1 (HTLV-1) carriers remains to be clarified. We here investigated whether plasma sCD30 is associated with risk of ATL in a nested case-control study within a cohort of HTLV-1 carriers. We compared sCD30 levels between 11 cases (i.e., HTLV-1 carriers who later progressed to ATL) and 22 age-, sex- and institution-matched control HTLV-1 carriers (i.e., those with no progression). The sCD30 concentration at baseline was significantly higher in cases than in controls (median 65.8, range 27.2-134.5 U/mL vs. median 22.2, range 8.4-63.1 U/mL, P=0.001). In the univariate logistic regression analysis, a higher sCD30 (${\geq}30.2U/mL$) was significantly associated with ATL development (odds ratio 7.88 and the 95% confidence intervals 1.35-45.8, P = 0.02). Among cases, sCD30 concentration tended to increase at the time of diagnosis of aggressive-type ATL, but the concentration was stable in those developing the smoldering-type. This suggests that sCD30 may serve as a predictive marker for the onset of aggressive-type ATL in HTLV-1 carriers.

Spatio-Temporal Monitoring of Soil CO2 Fluxes and Concentrations after Artificial CO2 Release (인위적 CO2 누출에 따른 토양 CO2 플럭스와 농도의 시공간적 모니터링)

  • Kim, Hyun-Jun;Han, Seung Hyun;Kim, Seongjun;Yun, Hyeon Min;Jun, Seong-Chun;Son, Yowhan
    • Journal of Environmental Impact Assessment
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    • v.26 no.2
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    • pp.93-104
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    • 2017
  • CCS (Carbon Capture and Storage) is a technical process to capture $CO_2$ from industrial and energy-based sources, to transfer and sequestrate impressed $CO_2$ in geological formations, oceans, or mineral carbonates. However, potential $CO_2$ leakage exists and causes environmental problems. Thus, this study was conducted to analyze the spatial and temporal variations of $CO_2$ fluxes and concentrations after artificial $CO_2$ release. The Environmental Impact Evaluation Test Facility (EIT) was built in Eumseong, Korea in 2015. Approximately 34kg $CO_2$ /day/zone were injected at Zones 2, 3, and 4 among the total of 5 zones from October 26 to 30, 2015. $CO_2$ fluxes were measured every 30 minutes at the surface at 0m, 1.5m, 2.5m, and 10m from the $CO_2$ releasing well using LI-8100A until November 13, 2015, and $CO_2$ concentrations were measured once a day at 15cm, 30cm, and 60cm depths at every 0m, 1.5m, 2.5m, 5m, and 10m from the well using GA5000 until November 28, 2015. $CO_2$ flux at 0m from the well started increasing on the fifth day after $CO_2$ release started, and continued to increase until November 13 even though the artificial $CO_2$ release stopped. $CO_2$ fluxes measured at 2.5m, 5.0m, and 10m from the well were not significantly different with each other. On the other hand, soil $CO_2$ concentration was shown as 38.4% at 60cm depth at 0m from the well in Zone 3 on the next day after $CO_2$ release started. Soil $CO_2$ was horizontally spreaded overtime, and detected up to 5m away from the well in all zones until $CO_2$ release stopped. Also, soil $CO_2$ concentrations at 30cm and 60cm depths at 0m from the well were measured similarly as $50.6{\pm}25.4%$ and $55.3{\pm}25.6%$, respectively, followed by 30cm depth ($31.3{\pm}17.2%$) which was significantly lower than those measured at the other depths on the final day of $CO_2$ release period. Soil $CO_2$ concentrations at all depths in all zones were gradually decreased for about 1 month after $CO_2$ release stopped, but still higher than those of the first day after $CO_2$ release stared. In conclusion, the closer the distance from the well and the deeper the depth, the higher $CO_2$ fluxes and concentrations occurred. Also, long-term monitoring should be required because the leaked $CO_2$ gas can remains in the soil for a long time even if the leakage stopped.

Effect of Nitrogen on Eleutheroside production and Adventitious Root Growth in Eleutherococcus koreanum Nakai Bioreactor Cultures (생물반응기를 이용한 섬오갈피나무의 부정근 배양시 질소농도 및 NH4+와 NO3- 비율이 부정근의 생육과 eleutherosides 함량에 미치는 영향)

  • Ahn, Jin-Kwon;Lee, Wi-Young;Park, Eung-Jun
    • Journal of Korean Society of Forest Science
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    • v.98 no.4
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    • pp.363-369
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    • 2009
  • This study was carried out to investigate the effect of ${NO_3}^-$ and ${NH_4}^+$ on the adventitious root growth and eleuthroside synthesis of Eleutherococcus koreanum in 5 L-bioreactor culture. The change in the medium components was also measured during culture. The fresh weignt of adventitious root reached to the highest level of 30.8 g FW/L in the presence of both 50 mM ${NO_3}^-$ and 10 mM $NH_4^+$, representing 3.6-fold increase compared to the 60 mM ${NH_4}^+$ alone. However, as the increase of the portion of ${NH_4}^+$, the root growth was decreased. However, the maximum eleutheroside B, E and E1 contents were $57.3{\mu}g/g$ DW, $188.4{\mu}g/g$ DW and $47.3{\mu}g/g$ DW, with 30 mM, 60 mM and 15 mM total nitrogen source, respectively. Fresh weight of adventitious root increased up to 6.8-fold of inoculum size within 9 weeks. The amounts of ${NH_4}^+$, $K^+$, ${NO_3}^-$ and ${PO_4}^-$ were decreased during culture periods. Based on these results, we suggest that various further studies are required to increase the biomass and the useful secondary metabilites.

Surface Modification of Steel Tire Cords via Plasma Etching and Plasma Polymer Coating : Part I. Adhesive properties (플라즈마 고분자 코팅에 의한 강철 타이어 코드의 표면 개질 : 제1부. 타이어 코드의 접착성)

  • Kang, H.M.;Chung, K.H.;Kaang, S.;Yoon, T.H.
    • Elastomers and Composites
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    • v.35 no.1
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    • pp.53-62
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    • 2000
  • Zinc plated steel tire cords were treated with RF plasma polymerization coating of acetylene or butadiene in order to enhance adhesion to rubber compounds. Plasma polymerization was carried out as a function of plasma power, treatment tune and gas pressure. In order to maximize adhesion, argon plasma etching was performed, with carrier gas such as argon, nitrogen and oxygen, while the adhesion of tire cords was evaluated via TCAT. Best results were obtained from a combination treatment of argon etching (90 W. 10 min, 30 mTorr) and acetylene plasma polymerization coating (10 W, 30 sec, 30 mTorr) with argon carrier gas (25/5:acetylene/argon). These samples exhibited a pull out force of 285N which is comparable to that obtained from the brass plated tire cords (290N).

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Effects of Irrigation Control by Time and Integrated Solar Radiation on Muskmelon Quality in Perlite Culture (펄라이트 재배시 시간 및 적산일사량에 의한 관수제어가 멜론의 품질에 미치는 효과)

  • 김혜진;김영식
    • Journal of Bio-Environment Control
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    • v.9 no.1
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    • pp.66-72
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    • 2000
  • Effects of irrigation control by time and integrated solar radiation on musknelon quality in perlite culture were investigated. Sugar content of melon flesh was high in the irrigation treatment at the following times 6:00, 8:00, 10:00, 11:00, 12:00, 12:30, 13:00, 13:30, 14:00, 14:30, 15:00, 16:00, and 17:00(T-2), compared to the irrigation treatment at every hour from 6:00 to 18:00(T-1) within the irrigation experiment controlled by time. Within the irrigation experiment controlled by integrated solar radiation, sugar content was as high as 15.7(Brix$^{\circ}$) in the 240Wh.m$^{-2}$ , compared to the 180, the 200, and the 220Wh.m$^{-2}$ . Fruit firmness was low in T-2 within the Irrigation experiment by time and in the 220Wh.m$^{-2}$ within the irrigation experiment by integrated solar radiation. Fruit size was smaller in the treatment controlled by integrated solar radiation than by the time treatment. Fruit weight was the heaviest in T-1. The weight of the shoot except for the fruit was lower in treatment of irrigation by integrated solar radiation than by time. In conclusion it is suggested that the appropriate integrated solar radiation pet each irrigation cycle should be 180~20Wh.m$^{-2}$ in the early growing stage, and then gradually increased to 240Wh.m$^{-2}$ from net formation to harvest time.

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Optimization of Batch Expression of Sesame Oil (참기름의 회분식 착유의 최적화)

  • 민용규;정헌상
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.24 no.5
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    • pp.785-789
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    • 1995
  • In order to optimize the batch expression of sesame oil, recovery of expressed oil(REO) from roasted and unroasted sesame seeds were observed at different temperature, pressure, pressing duration and moisture content, and relatinship between REO and effects of expression factors were analysed. REO was high at 2.5~4.5% moisture content, 30~$50^{\circ}C$ and 30~50MPa, and decreased abruptly with increasing moisture content above 4.5%. The optimum temperature, pressure, pressing duration and moisture content were $40.1^{\circ}C$, 54.4MPa, 21.7min and 1.3% for unroasted seeds and $44.4^{\circ}C$, 37.8MPa, 14.4min and 2.52% for roasted seeds, respectively. REO in optimum condition was 84.6% in unroasted seed and 81.7% in roasted seed. From the statistic analysis between effects of expression factors and REO, importance of their effects was decreased in the order of moisture content, pressure, temperature and pressing duration. And also interaction effects were high in $pressure{\times}moisture$ content, $temperature{\times}moisture$ content and temperature pressure. The multiple regression equation between REO(Y) and temperature(T), pressure(P), moisture content(M), and pressing duration(D) were as follows ; $Y=18.20$ $35.66P$$24.52M-4.45P^{2}-1.20TM-4.02PM-6.62M^{2},\;r^{2}=0.89$, for unrosated sesame seed, $Y=117.93$$16.40P-58.61M-2.75P^{2}$$1.79TM-1.65PM$$7.16M^{2},\;r^{2}$$=0.91$ for roasted sesame seed.

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HPLC-MS/MS Detection and Sonodegradation of Bisphenol A in Water (HPLC-MS/MS를 이용한 Bisphenol A 분석 및 초음파에 의한 분해 특성 조사)

  • Park, Jong-Sung;Yoon, Yeo-Min;Her, Nam-Guk
    • Journal of Korean Society of Environmental Engineers
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    • v.32 no.6
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    • pp.639-648
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    • 2010
  • The optimal conditions for the analysis of BPA by HPLC-MS/MS was investigated and the ultrasound degradation capacity of the BPA, with the goal to establish the proper directions for analyzing infinitesimal quantities of BPA by HPLC-MS/MS was examined. The MDL and LOQ of BPA analyzed by HPLC-MS/MS were measured 0.13 nM and 1.3 nM respectively, its sensitivity about 620 and 32 times greater than HPLC-UV (MDL: 81.1 nM, LOQ: 811 nM) and FLD (MDL: 4.6 nM, LOQ: 46 nM). In other words, the new method enables the analysis of BPA with the accuracy up to one 1,180th of the amount specified in U.S. EPA guideline for drinking water. Degradation rate of BPA by ultrasound measured over 95% under 580 kHz and 1000 kHz frequency within 30 minutes of treatment, whereas the rate showed some decrease at 28 kHz frequency. At 580 kHz of ultrasound has proven to be the most effective among others at degradation rate and $k_1$ value, so we concluded that this frequency of ultrasound creates hospitable condition for the combined process of degradation by pyrolysis and oxidization. With the addition of 0.01 mM of $CCl_4$, BPA with the initial concentration of 1 ${\mu}M$ was degraded by more than 98% within 30 minutes, the $k_1$ value measured 5 minutes and 30 minutes into the experiment both showed increases by 1.4 and 1.1 times, respectively, compared with BPA without $CCl_4$. It is also found that the main degradation mechanism of BPA by ultrasound is oxidization process by OH radical, based on the fact that the addition of 10 mM of t-BuOH decreased the rate of BPA degradation by around 60%. However, 33% of BPA degradation rate obtained with the addition of t-BuOH implies further degradation done by pyrolysis or other sorts of radical beside OH radical.

Purification and Some Properties of Peroxidase from the Fruit Malus sieboldii (Regel) Rehder (아그배 Peroxidase의 정제 및 특성)

  • Yang, Hee-Cheon;Son, Hee-Suk;Shim, Kyu-Kwang;Oh, Chan-Ho;Choi, Dong-Seong
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.21 no.1
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    • pp.84-90
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    • 1992
  • Peroxidase in the fruit of Malus sieboldii (Regel) Rehder was partially purified by DEAE-cellulose column chromatography and Ultro-AcA 54 gel filtration. The optimum pH of peroxidase was 4.5 and optimum temperature was $80^{\circ}C$. The enzyme was stable at pH 5.0 and below $30^{\circ}C$, and inactivated by heat treatment at $80^{\circ}C$ for 15min. In the presence of 30mM $H_{2}O_2$ Km value on o-phenylenediamine as substrate was 1.65mM, and in the presence of 10mM o-phenylenediamine Km value on $H_{2}O_2$ was 7.97mM. L-Ascorbic acid and sodium L-ascorbate greatly inhibited the enzyme activity and among several metal ions $Mn^{2+}$ only increased the activity at 5mM.

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Selection of Optimum Species of Tetraselmis for Mass Culture (대량배양에 적합한 Tetraselmis종의 선택)

  • 김철원;허성범
    • Journal of Aquaculture
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    • v.11 no.2
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    • pp.231-240
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    • 1998
  • Tetraselmis is widely used as a live food because of its easy handling, high nutrient, large size and wide tolerant range of temperature and salinity. In order to find the optimum Tetraselmis species for mass culture in Korea, five species of this microalgae were examined on size, optimum culture condition ${\textperthousand}$s, $^{\circ}C.$) and nutrient composition. The results obtained were as follows: Among five species of Tetraselmis, T. sp.(Haeundae) was the largest(major axis $17.6{\pm}1.87^{\mu}$m, mean cell volume 727${\mu}$m), and T. sp. (China) the smallest (major axis $14.6{\pm}1.46^{\mu}$m, mean cell volume 625m). Tetraselmis was very eurythermal and euryhaline species. But optimum temperature and salinity for growth were 24~$30^{\circ}C.$ and 27~30${\textperthousand}$, respectively. Among five species of Tetraselmis, T. sp. (China) seemed to be the most tolerant of high temperature over $30^{\circ}C.$, and T. tetrathele of low temperature below $6^{\circ}C.$. In culture density, T. suecica showed the highest growth rate among the among the five species. The cell density of this microalgae attained to $141{\times}10^4$cells/ml at $24^{\circ}C.$ and 30${\textperthousand}$ within 7 days. In chemical composition, crude protein amount was the highest in T. suecica (44.50%), and crude lipid amount it T. sp. (Haeundae, 7.13%). Total essential amino acid amount was the highest in T. sp. (Haeundae, 50.4%) and total polyunsaturated amount in T. sp. (China, 11.7%) The results on growth and chemical composition of five species of Tetraselmis indicated that T. suecica seemed to be the most suitable species for mass culture in Korea.

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ON DIFFERENTIAL INVARIANTS OF HYPERPLANE SYSTEMS ON NONDEGENERATE EQUIVARIANT EMBEDDINGS OF HOMOGENEOUS SPACES

  • HONG, JAEHYUN
    • Communications of the Korean Mathematical Society
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    • v.30 no.3
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    • pp.253-267
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    • 2015
  • Given a complex submanifoldM of the projective space $\mathbb{P}$(T), the hyperplane system R on M characterizes the projective embedding of M into $\mathbb{P}$(T) in the following sense: for any two nondegenerate complex submanifolds $M{\subset}\mathbb{P}$(T) and $M^{\prime}{\subset}\mathbb{P}$(T'), there is a projective linear transformation that sends an open subset of M onto an open subset of M' if and only if (M,R) is locally equivalent to (M', R'). Se-ashi developed a theory for the differential invariants of these types of systems of linear differential equations. In particular, the theory applies to systems of linear differential equations that have symbols equivalent to the hyperplane systems on nondegenerate equivariant embeddings of compact Hermitian symmetric spaces. In this paper, we extend this result to hyperplane systems on nondegenerate equivariant embeddings of homogeneous spaces of the first kind.