• Title/Summary/Keyword: M.P.S.

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A Study on Screening of Oriental Medicines Against Antibiotics-resistant Staphylococcus aureus (항생제(抗生劑) 내성(耐性) 화농균(化膿菌)의 생육(生育)을 억제(抑制)하는 한약재(韓藥材) 탐색(探索)에 관(關)한 硏究(연구))

  • Park, Won-Young;Seo, Woon-Gyo;Jeong, Ji-Cheon
    • The Journal of Internal Korean Medicine
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    • v.19 no.2
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    • pp.300-316
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    • 1998
  • The various oriental herbal medicines, which have usually been used for treatment of reducing fever, purging intense heat and detoxication, were screened to determine the antibacterial activity and the minimal inhibitory concentration against antibiotics-resistant Staphylococcus aureus. The results obtained were as follows: 1. Among the 23 oriental medicines tested, the water-soluble extract of Coptis japonica showed very excellent antibacterial activity against antibiotics-sensitive and -resistant S. aureus. A little activity was found in the extracts of Scutellaria baicalensis, Eriobotrya japonica and Prunus mume against antibiotics-sensitive S. aureus and in that extracts of P. mume, Schizandra chinensis and S. baicalensis against antibiotics-resistant S. aureus. When C japonica was used, the high antibacterial activity was shown against Bacillus subtilis and other extracts showed a little or no antibacterial activity against B. subtilis and E. coli as a control. 2. The highest antibacterial activities against antibiotics-resistant S. aureus were found in the ethanol-soluble extract of C japonica. Other ethanol-soluble extracts of S, baicalensis, S. chinensis and P. mume showed a little activity against both antibiotics-sensitive and antibiotics-resistant S. aureus. 3. Among the medicinal herbs tested, the water- and ethanol extracts of C. japonica showed very excellent antibacterial activity against the pathogenic S. aureus and both Escherichia coli and Bacillus subtilis used as a control. 4. When the water-soluble extracts of C. japonica and S. baicalensis, minimal inhibitory concentrations (MICs) against antibiotics-sensitive S. aureus were $20mg/m{\ell}\;and\;30mg/m{\ell}$, respectively. The MICs of the ethanol-soluble extracts of C. japonica and P. scabriosaefolia were $7.5mg/m{\ell}\;and\;12mg/m{\ell}$, respectively. 5. For the MICs against antibiotics-resistant S. aureus, the water-soluble extracts of C. japonica and P. mume showed $15mg/m{\ell}\;and\;10mg/m{\ell}$, respectively. The MICs of the ethanol-soluble extracts of C. japonica and P. mume were $13mg/m{\ell}\;and\;20mg/m{\ell}$, respectively. As a result, the highest antibacterial activity was found in both water- and ethanol-soluble extracts of C. japonica against antibiotics-resistant S. aureus. And the water- and ethanol-soluble extracts of S. baicalensis, S. chinensis and P. mume showed comparatively high antibacterial activities against both antibiotics-sensitive and -resistant S. aureus.

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BOUNDARIES OF THE CONE OF POSITIVE LINEAR MAPS AND ITS SUBCONES IN MATRIX ALGEBRAS

  • Kye, Seung-Hyeok
    • Journal of the Korean Mathematical Society
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    • v.33 no.3
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    • pp.669-677
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    • 1996
  • Let $M_n$ be the $C^*$-algebra of all $n \times n$ matrices over the complex field, and $P[M_m, M_n]$ the convex cone of all positive linear maps from $M_m$ into $M_n$ that is, the maps which send the set of positive semidefinite matrices in $M_m$ into the set of positive semi-definite matrices in $M_n$. The convex structures of $P[M_m, M_n]$ are highly complicated even in low dimensions, and several authors [CL, KK, LW, O, R, S, W]have considered the possibility of decomposition of $P[M_m, M_n] into subcones.

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Hypersurfaces with quasi-integrable ( f, g, u, ʋ, λ) -structure of an odd-dimensional sphere

  • Ki, U-Hang;Cho, Jong-Ki;Lee, Sung Baik
    • Honam Mathematical Journal
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    • v.4 no.1
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    • pp.75-84
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    • 1982
  • Let M be a complete and orientable hypersurface of an odd-dimensional sphere $S^{2n+1}$ with quasi-integrable $(f,\;g,\;u,\;{\nu},\;{\lambda})$ -structure. The purpose of the present paper is to prove the following two theorems. (I) If the scalar curvature of M is constant and the function $\lambda$ is not locally constant, then M is a great sphere $S^{2n}$(1) or a product of two spheres with the same dimension $S^{n}(1/\sqrt{2}){\times}S^{n}(1/\sqrt{2})$. (II) Suppose that the sectional curvature of the section $\gamma(u,\;{\nu})$ spanned by u and $\nu$ is constant on M and M is compact. If the second fundamental tensor H of M is positive semi-definite and satisfies trace $$^{t}HH{\leq_-}{2n}$$, then M is a great sphere $S^{2n}$ (1) or a product of two spheres $S^{n}{\times}S^{n}$ or $S^{p}{\times}S^{2n-p}$, p being odd.

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Electrochemical Studies on the Heavy Lanthanide Complexes (무거운 란탄족 이온 착물의 전기화학적 연구)

  • Pak, Chong Min;Kim, Chae Kyun;Son, Byung Chan
    • Analytical Science and Technology
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    • v.5 no.3
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    • pp.249-261
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    • 1992
  • Electrochemical behavior of the heavy lanthanide complexes of alizarin red S(ARS) has been investigated by d. c. polarography, differential pulse polarography and cyclic voltammetry. The reduction mechanism at a mercury electrode of alizarin red S as a complexing ligand showed a one step of two-electron transfer and the electron process is found to be reversible. Alizarin red S forms a 3:1 adsorptive complexes with lanthanides and the complexes are reduced via one step of two-elctron. The reduction potential of complex wave($P_2$) shifted more negatively than the ligand wave($P_1$). The linear calibration curves of the decreacing $P_1$ and increasing $P_2$ is obtained when the lanthanide concentration varies from $2.0{\times}10^{-6}M$ to $6.4{\times}10^{-5}M$ under the condition of pH 9.5, 0.1M LiCl and $1{\times}10^{-3}M$ ARS.

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Synthetic Studies on the Nucleophilic Addition of 1-Methyl-5-mercapto-1,2,3,4-tetrazole to Vinylsulfilimines (Vinylsulfilimine유도체에 대한 1-methyl-5-mercapto-1,2,3,4-tetrazole의 친핵성 첨가물에 관한 연구)

  • Tae-Rin Kim;So-Young Lee;Sang-Yong Pyun
    • Journal of the Korean Chemical Society
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    • v.36 no.2
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    • pp.318-323
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    • 1992
  • Following seven new nucleophilic adducts of sulfilimine compounds were prepared by the addition of 1-methyl-5-mercapto-1,2,3,4-tetrazole to vinylsulfilimine derivatives; S-Phenyl-S-2-(1-methyl-1,2,3,4-tetrazole-5-thio)-ethyl-N-p-tosylsulfilimine, S-p-tolyl-S-2-(1-methyl-1,2,3,4-tetrazole-5-thio)-ethyl-N-p-tosylsulfilimine, S-m-tolyl-S-2-(1-methyl-1,2,3,4-tetrazole-5-thio)-ethyl-N-p-tosylsulfilimine, S-p-chlorophenyl-S-2-(1-methyl-1,2,3,4-tetrazole-5-thio)-ethyl-N-p-tosylsulfilimine, S-p-bromophenyl-S-2-(1-methyl-1,2,3,4-tetrazole-5-thio)-ethyl-N-p-tosylsulfilimine, S-p-methoxyphenyl-S-2-(1-methyl-1,2,3,4-tetrazole-5-thio)-ethyl-N-p-tosylsulfilimine and S-p-nitrophenyl-S-2-(1-methyl-1,2,3,4-tetrazole-5-thio)-ethyl-N-p-tosylsulfilimine. The structures of these adducts were confirmed by elemental analyses, MP, UV, IR-and NMR-Spectra.

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Effect of Schizandra chinensis and Pine Meddle on Growth of Pathogens Relate to Acne. (여드름 원인균의 성장에 미치는 오미자와 솔잎의 효과)

  • 성준모;박나영;이신호
    • Microbiology and Biotechnology Letters
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    • v.31 no.1
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    • pp.69-74
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    • 2003
  • Antimicrobial effect of Schizandra chinensis and pine neddle against various pathogens relate to acne (comedones). Ethanol extracts of Schizandra chinensis and pine neddle showed antimicrobial activity against Malassezia furfur Staphylococcus epidermidis and Propionibacterium acnes . The growth of M. fufur and S. epidermidis was inhibited completely by addition of 0.12% Schizandra chinensis extract to YM broth (YM) and tryptic soy broth (TSB) after 24 h incubation. The growth of Propionibacterium acnes was completely inhibited on YM and TSB containing 0.06% of ethanol extract of Schizandra chinensis and pine neddle, respectively. Minimum inhibitory concentration (MIC) of Schizandra chinensis and pine neddle against P. acnes was 0.0075% (75 $\mu\textrm{g}$/mL). The antimicrobial activities of Schizandra chinensis and pine noddle did not decrease apparantly by heat treatment at $80^{\circ}C$ for 30 min, 10$0^{\circ}C$ for 30 min and $121^{\circ}C$ for 15 min, respectively.

A Study on the Stress of Family-Caregivers and Level of Daily Living Performance with Patients of Cerebra Vascular Accident(CVA) (뇌졸중환자의 일상생활 수행수준과 가족원의 스트레스)

  • Cho, Young-Hee
    • Research in Community and Public Health Nursing
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    • v.10 no.2
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    • pp.372-386
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    • 1999
  • The purpose of this study was to explore the degree of stress in caregivers caring for CVA patients and the level of daily living performance of CVA patients. The subjects for the study were caregivers of 112 CVA patients who enter a hospital or out-patient-department (OPD) at two Oriental medical hospital in Jeonbuk province. The survey instruments used in this study were Kang's ADL check list for daily living performance of patients and Choi's 4 sore scale for stress of caregivers. The survey was conducted from July 4th to August 30th in 1999. The survey results were analyzed with the Statistical Package for Social Science(SPSS) program and can be summarized as follows: 1. The level of daily living performance for the CVA patients was: 1) complete dependence (M=14.9, 13.1%), 2) complete independence (M=23.6, 20.9%), 3) incomplete independence (M=23.9, 21.0%), 4) incomplete dependence (M=26.6, 25%), 5) dependence and independence (M=23.0, 20.0%). The items for with there was a high level daily living performance were: 1) drinking (M=3.62), 2) eating(M=3.25). 3) position returning (M=3.18) : and the items for which there was a low level of daily living performance were: 1) ascending and descending stairs (M=2.08), 2) walking (M=2.47), 3) dressing and undressing trousers (M=2.55). 2. Degree of caregiver stress was: Mean=2.39 at 40 score. The items for which was a high level caregiver stress were: 1) medical fee (M=3.25), 2) being handicapped or recurrence (M=3.02) : and the items for which there was a low level of caregiver stress were: 1) discontinuity of patient's treatment (M = 1.98). 2) change of home atmosphere caused by patient's disease (M = 1.98), 3) desire of patient's knowing about disease (M= 1.99). 3. There was statistically significant difference in the degree of caregiver stress according to the following caregiver's demographic characteristics: education level (F=3.52, P=0.03). change of caregiver (F=5.41. P=0.02). 4. There was a statistically signifiant difference in the level of daily living performance according to the CVA patients demographic characteristics: patient's paralytic status (F=4.48, P=0.01), duration of disease (t=2.76, P=0.03). 5. There was significant difference in degree of caregiver stress according to the CVA patient's demographic characteristics: CVA status (F=4.75, P=0.01). 6. There was statistically significant difference in the degree of caregiver stress according to the level of daily living performance in CVA patients(r=-0.482, P<0.00).

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A Study on the Dynamic Characteristics of on-shore Ground Using Suspension P. S. Logging (서스펜션 P.S. 검층을 이용한 해저 지반의 동역학적 특성에 관한 연구)

  • 김용수;정승용;장찬수;김수삼
    • Proceedings of the Korean Geotechical Society Conference
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    • 1999.10a
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    • pp.357-364
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    • 1999
  • In recently site investigations, the need for the determination of dynamic soil properties such as dynamic modules of rigidity, elasticity, dynamic poison's ratio and damping ratio etc. is increasing for the astigmatic designs of the civil structures. To obtain some of the dynamic properties, measurement of elastic waves velocity, both P and S wave, is required. Among various methods to measure elastic wave velocity such and Down Hole, Cross Hole and Refraction etc., Suspension P.S. Logging has an advantage to use for the off-shore investigation where generation of the shock wave and traveling of the wave is difficult. In suspension P.S. logging, specially designed prove equipped with source of shock wave, two 3-channel receivers, departing 1m distance, and other auxiliary facilities is inserted down in a bore hole bottom and raised in predetermined interval, usually 1m or 2m, and measurement is conducted. P.S. logging have been conducted in a off-shore construction project near InChon in the west coast for the first in the country, and form the result, potential of the liquefaction of the subsoil was evaluated and compared with the conventional method.

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독성물질 대사효소 조절기전에 관한 연구

  • 윤여표;홍연탁;김부영
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1992.05a
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    • pp.54-54
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    • 1992
  • 약물, hormone, 독성물질등의 대사능과 발암 가능성등이 간장 장해시 및 ketosis시에 달라지는 원인과 기전, 독성물질 대사효소의 변동과 그 작용기전을 규명하고자, 대표적인 간장장해 물질인 carbon tetrachloride를 rat에 투여하여 간장 장해를 일으키고, 당뇨병, starvation, high-fat diet처리하여 ketosls상태를 만든 후에, specific cytochrome P45O polyclonal antibodies와 cDNA probes를 사용하여, enzyme activitieg, Western immunoblot analysis와 mRNA Northern blot analysis 등을 실험하여, 간장 장해와 ketosis시 cytochrome P45O의 변동과 그 작용기전, regulation을 규명하고자 하였다. 실험 결과, $CCl_4$투여후 P450IIE enzyme (aniline hydroxylase) 활성이 시간 의존적으로 급격히 떨어졌고, P450IIE protein양이 똑같은 방식으로 감소되었으나 mRNA level은 변화가 없었다. $CCl_4$에 의해서 P450IIE는 protein의 특이적인 파괴에 의한 post-translational reduction됨을 알 수 있었다. 반면에 당뇨병, starvation, high-fat diet등 ketosis시에는 P450IIE 효소활성이 2-3배 증가되었고, P450IIE protein양도 같은 수준으로 증가되었으며, mRNA도 증가 되었다. Ketosis시에는 P450IIE가 pretranslational activation됨을 알 수 있었다.

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EVOLUTION OF HUMAN DENTITION (사람 치열의 진화)

  • Lee, Kwang-Hee
    • Journal of the korean academy of Pediatric Dentistry
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    • v.34 no.3
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    • pp.532-542
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    • 2007
  • The purpose of study was to review the transition of dentition according to the evolution of man to know the background of the dental problems like hypodontia and malocclusion. Man is Kingdom Animalia, Phylum Chordata, Class Mammalia, Order Primates, Suborder Haplorrhini, Superfamily Hominoidea, Family Hominidae, Genus Homo, Species Sapiens by taxonomy. The first hominid was Australopithecus which appeared c. 4 millions of years ago and showed bipedalism and distinct dentition. Homos began with H. habilis who appeared c. 2.5 millions of years ago and made stone tools, and then H. erectus and H. neanderthalensis appeared and disappeared until H. sapiens came. The dental formula of primitive mammalians which was I3 C1 P4 M3 changed to I2 C1 P4 M3 of primitive primates, to I2 C1 P3 M3 of Haplorrhini, and to I2 C1 P2 M3 of hominoids. That of H. sapiens is changing to I2 C1 P2 M2.The box type dentition of hominoids changed to the omega type dentition of Australopithecus, and to the parabolic type of H. sapiens. The size of teeth decreased continually, especially the canine and sexual dimorphism. The dentition moved backward and downward to the cranial crown according to the increase of the brain and decrease of the jaws. It was suggested that the change of diet to the starchy foods, food processing, and the development of cooking reduced the necessity of mastication and caused the change of dentition. The future of H. sapiens who is quite a new species in the earth histroy and is now causing the mass extinction of other species is hard to see. It seems that hypodontia and malocclusion are related to the dentition change according to the evolution of man and is likely to increase.

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