• 동의생리병리학회지
• /
• 제36권1호
• /
• pp.18-22
• /
• 2022

To investigate effects of cognitive function improvement whether against Taegeuk ginseng on scopolamine-induced memory impairment in rats. All experiments were conducted in three groups: the control group (CTR), the scopolamine 0.4mg/kg (SCP), and the scopolamine (SCP+T) treated with Taegeuk ginseng 100 mg/kg. Taegeuk ginseng 100 mg/kg daily was orally administered for one month and treated with scopolamine was only for 7 consecutive days on the Morris water maze task. 3 weeks after oral administration of Taegeuk ginseng, subjects were performed the Morris water maze test for 8 days and then the open-field exploration test which to assessed for cognitive function improvement. After behavioral testing, subjects were sacrificed and microdissected brains for neurochemical analysis. In the cognitive-behavioral test, long-term administration of Taegeuk ginseng improved spatial navigation learning task compared with the impeded by scopolamine treatment. In neurochemistry, the expression of the synaptic marker PSD95 (postsynaptic density protein 95) was increased in the hippocampus compared to the scopolamine group. Also, brain-derived neurotrophic factor (BDNF) expression was significantly increased in the taegeuk ginseng administration group. These data suggested that long-term administration of taegeuk ginseng might improve cognitive-behavioral functions on hippocampal related spatial learning memory, and it was correlated with neurotropic and synaptic reinforcement. In conclusion, treatment with taegeuk ginseng may positive outcome on learning and memory deficit disorders.

• 한국산업정보학회논문지
• /
• 제15권4호
• /
• pp.7-15
• /
• 2010

본 연구는 SC-FDMA(Single Carrier-Frequency Division Multiple Access) 접속기술을 사용하는 LTE(Long Term Evolution) 상향링크의 성능을 최대화하기 위한 무선자원관리(radio resource management) 기법을 제안한다. 셀간의 상호작용을 고려해야하는 다중셀(multi-cell) 시스템을 대상으로 하여 단일셀 대상의 기존 SC-FDMA관련 연구와는 차별화된다. 본 연구는 무선자원관리를 무선자원 계획단계(planning phase)와 운용단계(operation phase)로 구분하여 정의한다. 계획단계는 마스터 eBN(evolved-NodeB)가 소속된 eNB에 연속적인 무선자원(RB; radio bearer)를 배정하기 위한 것이고 운용단계는 eNB가 마스터 eBN로부터 배정받은 RB를 단말기에 할당하기 위한 것이다. 두 단계에 대하여 각각 최적화 문제를 모형화하고 각 모형에 대한 탐색적 해법을 제시한다. 제시하는 해법은 인접해중에서 목적함수 개선치가 가장 높은 방향으로 이동하는 일반적인 형태를 띄고 있다. 다수의 실험결과를 통하여 두 알고리즘의 성능과 특징을 분석하였다. 본 연구는 다중셀 SC-FDMA 시스템을 대상으로 효율적인 무선자원 관리 기법을 개발하기 위한 연구에 선구자적인 역할을 할 것으로 기대된다.

• 한국미생물·생명공학회지
• /
• 제24권6호
• /
• pp.717-725
• /
• 1996

We have developed an efficient immobilized cell separator for continuous operation of immobilized fungal cell cultures, and applied this separator to actual fermentation process for the production of cyclosporin A (CyA), a powerful immunosuppressant. In the experiments employing highly viscous polymer (carboxymethyl cellulose) solution, the decantor showed good separating performances at high solution viscosites and fast dilution rates. Air duct and cylindrical separator installed inside the decantor turned out to play key roles for the efficient separation of the immobilized cells. By installing the decantor in an immobilized perfusion reactor system (IPRS), continuous immobilized culture was stably carried out even at high dilution rate for a long period, leading to high productivities of free cells and CyA. Almost no immobilized biomass existed in effuluent stream of the IPRS, demonstrating the effectiveness of the decan- tor system for a long-term continuous fermentation. It was noteworthy that we could obtain these results despite of the unfavorable fermentation conditions, i.e., reduced density of the biosupports caused by overgrowth of cells inside the bead particles and existence of high density of suspended fungal cells (10g/l) in the fermentation broth.

• 대한기계학회논문집
• /
• 제16권8호
• /
• pp.1421-1428
• /
• 1992

본 연구에서는 실제 고온, 고압용기에 장기 사용하여 재료 특성이 변화된 열 화재와 열화재를 열처리하여 충격치를 회복시킨 회복재의 두 종류의 재료를 사용하여 탄소성 파괴 인성치 J$_{IC}$실험을 수행하여 장기사용에 따른 재질열화에 의한 파괴 인성치의 변화 상태를 검토해 보고, 이를 응용한 수명예측 즉, 3차원 표면 균열을 갖 인 판이 열화된 경우와 건전한 경우를 가정하여 피로 파괴 과정중 파단 특성에 어떤 차이가 일어날까에 대해 연구 검토해 보았다.

• 한국분무공학회지
• /
• 제18권1호
• /
• pp.9-15
• /
• 2013

Wall thinning of pipeline in power plants occurs mainly by flow acceleration corrosion (FAC), cavitation erosion (C/E), liquid droplet impingement erosion (LDIE). Wall thinning by FAC and C/E has been well investigated; however, LDIE in plant industries has rarely been studied due to the experimental difficulty of setting up a long injection of highly-pressurized air. In this study, we designed a long-term experimental system for LDIE and investigate the behavior of LDIE for three kinds of materials (A106B, SS400, A6061). The main control parameter was the air-water ratio (${\alpha}$), which was defined as the volumetric ratio of water to air (0.79, 1.00, 1.72). In order to clearly understand LDIE, the spraying velocity (${\nu}$) of liquid droplets was controled larger then 160 m/s and the experiments were performed for 15 days. Therefore, this research focuses relation between erosion rate and air-water ratio on the various pipe-flow materials. NPP(nuclear power plant)'s LDIE prediction theory and management technique were drawn from the obtained data.

• Current Photovoltaic Research
• /
• 제7권3호
• /
• pp.71-75
• /
• 2019

Solar energy is one of the renewable energy sources. It can respond to expanding energy demand. A solar cell module is designed to have a durability that can be developed over a long period of 25 years to be installed outdoors and perform like a stable power supply. We need Standard Test Condition (STC)-based power output data before and after testing to measure the power output of existing modules. The modules are shown to reduce power output by comparing data before and after outdoor experiments regardless of whether they are indoor or outdoor. It is easy to compare the power output quantities through the module simulator in the indoor. However, it takes a lot of testing time and costs to compare the power output on outdoor in the case of a high number of modules and distance from the module simulator. It can save time and costs if we can check the power output using the data in outdoor. We have used the long-term outdoor test to find the elements out that corresponds to the reductions in power output quantities. We have conducted research that matched the actual and the tests.

• Nuclear Engineering and Technology
• /
• 제56권4호
• /
• pp.1385-1397
• /
• 2024

Bentonite is a recommended material for the multiple barriers in the final disposal of low-level radioactive waste (LLW) to prevent groundwater intrusion and nuclear species migration. However, after drying-wetting cycling during the repository construction stage and ion exchange with the concrete barrier in the long-term repository, the bentonite mechanical behaviors, including swelling capacity and hydraulic conductivity, would be further influenced by the groundwater intrusion, resulting in radioactive leakage. To comprehensively examine the factors on the mechanical characteristics of bentonite, this study presented scenarios involving MX-80 and KV-1 bentonites subjected to drying-wetting cycling and accelerated ion migration. The experiments subsequently measured free swelling, swelling pressure, and hydraulic conductivity of bentonites with intrusions of seawater, high pH, and low pH solutions. The results indicated that the solutions caused a reduction in swelling volume and pressure, and an increase in hydraulic conductivity. Specifically, the swelling capability of bentonite with drying-wetting cycling in the seawater decreased significantly by 60%, while hydraulic conductivity increased by more than three times. Therefore, the study suggested minimizing drying-wetting cycling and preventing seawater intrusion, ensuring a long service life of the multiple barriers in the LLW repository.

• Fisheries and Aquatic Sciences
• /
• 제5권3호
• /
• pp.191-199
• /
• 2002

Pacific oysters Crassostrea gigas (Thunberg) were collected on April, 1999 and March­September, 2000 from Goseung Bay along the southern coast of Korea. The oysters tested cp;;ected from a depth of 0.5-2 m in which they cultured by a long line hanging method. The oxygen consumption rates (OCR) of oysters held under constant temperature and darkness (CC), were determined using an automatic intermittent-flow-respirometer (AIFR). Depending on holding periods after oyster collection, the experiments were divided into two groups: Group 7-d (held to ambient temperature for ca. 7 days) and Group 2l-d (held to ambient temperature for ca. 21 days). The OCR for Group 7-d single oyster displayed two peaks every day under CC, while Group 2l-d single oyster showed one peak every day. It is likely that the rhythmic patterns 02.6-12.8 hours) of the OCR in the Group 7-d single oyster may have been influenced by tidal currents at the sampling site. The rhythmic patterns (24.3-24.7 hours) in the Group 2l-d single oyster may have been shifted from two peaks to one peak each day under CC. The present study concludes that the OCR rhythm of wild oysters in nature is governed by two lunar-day clocks (24.8 hours); one driving one peak and the other driving the second peak. When oysters are subjected to the long-term CC conditions, one of the two-clock systems is depressed or only intermittently becomes active. Jpwever. the OCR rhythms by two to three oysters occurred arrhythmic patterns during the experiments and exhibited some evidence of weak rhythmicity of compared to those of a single oyster. It could be partly due to differences group effects.

• Journal of Biosystems Engineering
• /
• 제19권3호
• /
• pp.232-246
• /
• 1994

This study was conducted to develop the long-tenn storage method to minimize the black spot occurred on the surface of persimmons stored in the films at low temperature. The storage experiments were done with different films and persimmon varieties at $0^{\circ}C$ storage condition for 5 months, and then the physical and chemical characteristics of persimmons were tested monthly. The results were as follows : 1. The film 160 made from zeolites showed highest performance in well storings sweet persimmons for 5 months, compared with other films by eyesight. The initial moisture condensation inside the films seemed to cause the black spots on persimmons, and the effect of the film holes was never significant to prevent the black spots. 2. The sugar content was ranged from $14^{\circ}Brix$ to $15^{\circ}Brix$ regardless of film types and persimmom varieties, and it changed little for storage of 5 months. 3. The decrease rate of persimmom weight in the film 160 and 180 was 0.3% for storage of 5 months, while those in other films reached to 2%. The decrease rate of persimmon weight was least in the film 160 and 180. 4. The hardness of Fuyu least decreased in the films 160 and 380. It was changed from 36 kg/cnf to 8-27 $kg/cm^2$, and that of Charyang was from 31 $kg/cm^2$ to 8-10 $kg/cm^2$ for storage of 5 months. The hardness of Charyang rapidly decreased as storage period increased. 5. The average rate of black spot(defect rate) of Fuyu measured by a computer image processing system was least in the film 160 by 0.5%, but those in other films was ranged from about 5% to 20% for storage of 5 months. The rate of black spot of Charyang was less than that of Fuyu among most of films. 6. The intensity, hue, and saturation in persimmon color changed according to storage period. Especially, the intensity of persimmon colors decreased as storage period increased, but it was least in the film 160. 7. An integrated long-term storage method of sweet persimmons was suggested in the basis of the experiments and literature reviews.

• 태양에너지
• /
• 제10권3호
• /
• pp.19-26
• /
• 1990

제작과 시공이 간편하고 저렴한 유하식 집열기의 열성능에 대하여 이론적 해석을 수행하였다. 개선된 이론해석의 결과는 실험결과를 잘 예측하였으며, 이 결과는 유하식 집열기를 이용한 저가 집열 시스템의 장기 열성능 해석 프로그램에 이용되었다. 문답식으로 짜여진 장기 열성능 프로그램은 f-chart 설계법에 근거하였으며, 저가 집열 시스템의 설계 및 경제성 분석에 쉽게 이용할 수 있다.