• 응용통계연구
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• 제17권3호
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• pp.489-498
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• 2004

이 논문에서는 일반화가중선형모형이라는 새로운 형태의 선형모형을 제시한다. 일반화가중선형모형은 설명변수와 반응변수의 관계를 설명분포함수의 선형결합이 반응변수의 평균에 대한 연결분포함수를 통해 모형화 되는 형태를 가지는 것으로 가정한다. 이모형은 일반화선형 모형에서 연결함수를 선택할 때 발생할 수 있는 모수공간과 선형 예측값의 공간이 일치하지 않을 수 있다는 문제가 발생하지 않고 모수에 대한 해석이 용이하다는 장점이 있다. 이 논문에서는 설명분포함수와 연결분포함수를 선택하는데 있어 발생할 수 있는 문제와 해결책에 대해 알아본다. 또한 모형에 포함되어 있는 모수를 추정하는데 고려해야 할 주의 사항과 이 사항들을 고려한 최대가능도추정법과 재표집 방법을 이용한 구간추정과 가설검정에 대해 알아본다.

• 응용통계연구
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• 제30권1호
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• pp.95-102
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• 2017

감마 일반화 선형모형은 포아송 분포 또는 이항 분포에 기반한 일반화 선형모형에 비해 적은 관심을 받아왔다. 따라서 감마 일반화 선형모형에서는 오래전에 개발된 통계적인 기법이 아직도 사용되고 있으며, 특히 산포 모수에 대해서는 근사 추정치가 여전히 사용되고 있다. 본 논문에서는 감마 일반화 선형 모형의 산포 모수에 대해 다양한 추정량들을 알아보고 수치 연구를 통해 그들의 효율성을 비교한다. 수치 실험의 결과 최대 가능도 추정량과 Cox-Reid의 수정된 최대 가능도 추정량이 기존의 근사 추정량에 비해 좋은 성능을 보임을 확인하였다.

• Molecules and Cells
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• 제45권7호
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• pp.444-453
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• 2022

Multivalent macromolecular interactions underlie dynamic regulation of diverse biological processes in ever-changing cellular states. These interactions often involve binding of multiple proteins to a linear lattice including intrinsically disordered proteins and the chromosomal DNA with many repeating recognition motifs. Quantitative understanding of such multivalent interactions on a linear lattice is crucial for exploring their unique regulatory potentials in the cellular processes. In this review, the distinctive molecular features of the linear lattice system are first discussed with a particular focus on the overlapping nature of potential protein binding sites within a lattice. Then, we introduce two general quantitative frameworks, combinatorial and conditional probability models, dealing with the overlap problem and relating the binding parameters to the experimentally measurable properties of the linear lattice-protein interactions. To this end, we present two specific examples where the quantitative models have been applied and further extended to provide biological insights into specific cellular processes. In the first case, the conditional probability model was extended to highlight the significant impact of nonspecific binding of transcription factors to the chromosomal DNA on gene-specific transcriptional activities. The second case presents the recently developed combinatorial models to unravel the complex organization of target protein binding sites within an intrinsically disordered region (IDR) of a nucleoporin. In particular, these models have suggested a unique function of IDRs as a molecular switch coupling distinct cellular processes. The quantitative models reviewed here are envisioned to further advance for dissection and functional studies of more complex systems including phase-separated biomolecular condensates.

• Communications for Statistical Applications and Methods
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• 제28권2호
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• pp.189-204
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• 2021

In a regression analysis, a single best model is usually selected among several candidate models. However, it is often useful to combine several candidate models to achieve better performance, especially, in the prediction viewpoint. Model combining methods such as stacking and Bayesian model averaging (BMA) have been suggested from the perspective of averaging candidate models. When the candidate models include a true model, it is expected that BMA generally gives better performance than stacking. On the other hand, when candidate models do not include the true model, it is known that stacking outperforms BMA. Since stacking and BMA approaches have different properties, it is difficult to determine which method is more appropriate under other situations. In particular, it is not easy to find research papers that compare stacking and BMA when regression model assumptions are violated. Therefore, in the paper, we compare the performance among model averaging methods as well as a single best model in the linear regression analysis when standard linear regression assumptions are violated. Simulations were conducted to compare model averaging methods with the linear regression when data include outliers and data do not include them. We also compared them when data include errors from a non-normal distribution. The model averaging methods were applied to the water pollution data, which have a strong multicollinearity among variables. Simulation studies showed that the stacking method tends to give better performance than BMA or standard linear regression analysis (including the stepwise selection method) in the sense of risks (see (3.1)) or prediction error (see (3.2)) when typical linear regression assumptions are violated.

• 한국지능시스템학회:학술대회논문집
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• 한국퍼지및지능시스템학회 1997년도 추계학술대회 학술발표 논문집
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• pp.115-120
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• 1997

System identification is the task of inferring a mathematical description of a dynamic system from a series of measurements of the system. There are several motives for establishing mathematical descriptions of dynamic systems. Typical applications encompass simulation, prediction, fault diagnostics, and control system design. The paper demonstrates that neural networks can be used effective for the identification of nonlinear dynamical systems. The content of this paper concerns dynamic neural network models, where not all inputs to and outputs from the networks are measurable. Only one model type is treated, the well-known Innovation State Space model(Kalman Predictor). The identification is based only on input/output measurements, so in fact a non-linear Extended Kalman Filter problem is solved. Even for linear models this is a non-linear problem without any assurance of convergence, and in spite of this fact an attempt is made to apply the principles from linear models, an extend them to non-linear models. Computer simulation results reveal that the identification scheme suggested are practically feasible.

• Communications for Statistical Applications and Methods
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• 제19권6호
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• pp.885-898
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• 2012

In this paper, we consider Bayesian approaches to partially linear models, in which a regression function is represented by a semiparametric additive form of a parametric linear regression function and a nonparametric regression function. We make a comparative study on the performance of widely used Bayesian partially linear models in terms of empirical analysis. Specifically, we deal with three Bayesian methods to estimate the nonparametric regression function, one method using Fourier series representation, the other method based on Gaussian process regression approach, and the third method based on the smoothness of the function and differencing. We compare the numerical performance of three methods by the root mean squared error(RMSE). For empirical analysis, we consider synthetic data with simulation studies and real data application by fitting each of them with three Bayesian methods and comparing the RMSEs.

• 응용통계연구
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• 제31권4호
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• pp.475-484
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• 2018

감마 일반화 선형모형은 음이 아니며 치우침이 있는 반응변수에 유용한 모형으로 알려져 있다. 그러나 포아송 분포 또는 이항 분포에 기반한 일반화 선형모형에 비해 적은 관심을 받아왔다. 특히, 회귀계수의 유의성 검정에 대해서는 연구가 면밀히 되어 있지 않다. 본 논문에서는 감마 일반화 선형 모형의 검정에 대해 다양한 통계량들을 알아보고 수치 연구를 통해 그들의 성능을 비교한다. 수치 실험의 결과 부분 이탈도 검정 방법의 문제점이 나타났으며, 가능도비 검정 방법과 F-검정 방법이 좋은 성능을 보임을 확인하였다.

• 한국수학사학회지
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• 제29권6호
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• pp.353-363
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• 2016

In mathematical population ecology which is an academic field that studies how populations of biological species change as times flows at specific locations in their habitats, PDE models have been studied in many aspects and found to have different properties from the classical ODE models. And different approaches to PDE type models in mathematical biology are still being tried currently. This article investigate various forms to express diffusion effects and review the history of PDE models involving diffusion terms in mathematical ecology. Semi-linear systems representing the spatial movements of each individual as random simple diffusion and quasi-linear systems describing more complex diffusions reflecting interspecific interactions are studied. Also it introduce a few of important problems to be solved in this field.

• 한국도로학회논문집
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• 제14권4호
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• pp.83-91
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• 2012

PURPOSES : This study deals with Rotary by Accident Occurrence Location. The purpose of this study is to develop the accident models of rotary by location. METHODS : In pursuing the above, this study gives particular attentions to developing the appropriate models using multiple linear, Poisson and negative binomial regression models and statistical analysis tools. RESULTS : First, four multiple linear regression models which are statistically significant(their $R^2$ values are 0.781, 0.300, 0.784 and 0.644 respectively) are developed, and four Poisson regression models which are statistically significant(their ${\rho}^2$ values are 0.407, 0.306, 0.378 and 0.366 respectively) are developed. Second, the test results of fitness using RMSE, %RMSE, MPB and MAD show that Poisson regression model in the case of circulatory roadway, pedestrian crossing and others and multiple linear regression model in the case of entry/exit sections are appropriate to the given data. Finally, the common variable that affects to the accident is adopted to be traffic volume. CONCLUSIONS : 8 models which are all statistically significant are developed, and the common and specific variables that are related to the models are derived.

• Journal of Information Technology Applications and Management
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• 제11권1호
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• pp.117-135
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• 2004

Since human decision making behavior is likely to follow nonlinear strategy, it is conjectured that the human decision making behavior can be modeled better by nonlinear models than by linear models. All that linear models can do is to approximate rather than model the decision behavior. This study attempts to test this conjecture by analyzing human decision making behavior and combining the results of the analysis with predictive performance of both linear models and nonlinear models. In this way, this study can examine the relationship between the predictive performance of models and the existence of valid nonlinear strategy in decision making behavior. This study finds that the existence of nonlinear strategy in decision making behavior is highly correlated with the validity of the decision (or the human experts). The second finding concerns the significant correlations between the model performance and the existence of valid nonlinear strategy which is detected by Lens Model. The third finding is that as stronger the valid nonlinear strategy becomes, the better nonlinear models predict significantly than linear models. The results of this study bring an important concept, validity of nonlinear strategy, to modeling human experts. The inclusion of the concept indicates that the prior analysis of human judgement may lead to the selection of proper modeling algorithm. In addition, lens Model Analysis is proved to be useful in examining the valid nonlinearity in human decision behavior.