• Journal of dental hygiene science
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• v.9 no.2
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• pp.181-187
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• 2009

Oral diseases may hinder people from living a healthy life by causing obstacles in the nutrition supply of the human body. This study aims at the found out the eating habits and recognition factors of people who are currently suffering from denial pain, and made a predictive modeling using neural network, which is a data mining. The oral health condition for maintaining and improving oral health has been examined and analyzed through a survey and the groups were divided based on the presence and the absence of dental pain. This study observed on eating habits, exercise and oral habits. The study results of neural network modeling input parameter was selected significant survival factors. As a result of making a predictive modeling using the neural network, the fitness of the predictive modeling of dental pain factors was 88.7%. As for the people who are likely to experience dental pain predicted by the neural network model, preventive measures including proper eating habits, education on oral hygiene, and stress release must precede any dental treatment.

• Journal of agriculture & life science
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• v.45 no.5
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• pp.17-23
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• 2011

Growth characteristics and adaptability of 10 poplar clones planted at a reclaimed tidal flat were evaluated. The contents of $Na^+$, $Ca^{2+}$ and $Mg^{2+}$ were 10.0, 3.4 and 1.5 times higher, respectively than those of control although the electrical conductivity(EC) in the soil at the test plantation was low as much as 0.51 dS/m. The contents of organic matter(OM) and total nitrogen(TN) in the soil were 22.9 and 23.0 times lower than those of control. Average survival rate of 10 poplar clones showed 88% at three years after planting. Clones Eco28(Populus euramericana), Dorskamp(Populus deltoides ${\times}$ P. nigra) and I-476(Populus euramericana) showed the best survival rate of 100%. However, clones 97-19(Populus deltoides(Lux) ${\times}$ P. deltoides(Harvard)) and Suwon (Populus koreana ${\times}$ P. nigra var. italica) were relatively lower than other clones. Average height and DBH of all clones were 4.8 m and 3.6 cm, respectively. Clone Dorskamp showed the greatest height and DBH, 5.9 m and 5.0 cm, respectively. Clones 97-19 and Dorskamp showed the least defoliation by stress and visible damage by insects and diseases, whereas clones Suwon and I-476 were the most sensitive at the reclaimed tidal flat. Clone Dorskamp showed the best adaptability at the reclaimed tidal flat, but clone Suwon showed the worst based on survival rate, growth, and visible damages.

• Journal of Family Resource Management and Policy Review
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• v.25 no.1
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• pp.35-45
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• 2021

Focusing on increasing of single-person households this study aims to develop a scale to measure the healthiness of lifestyle among single-person households. The concept of healthiness of lifestyle is based on the theories of family strength and family ecology. We draw 50 items that encompass basic needs, individual, familial, and social aspects of single-person life. Using a sample of 317 persons who live alone, this study examined a factor structure of the items and selected 44 items based on the results of factor analysis. Reliability and criterion- and construct validity were also examined. The final scale consists of four domains; basic needs (finance, housing, consumption, and future plan), work·life balance (time management, health, and stress), family relations, and social participation (social network, social interests, and community participation). This scale can be used as an assessment measure of the healthiness of lifestyle of single persons who participate in programs in Healthy and Multicultural Families Support Centers.

• Korean Journal of Psychosomatic Medicine
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• v.29 no.2
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• pp.77-85
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• 2021

Breast cancer is the most prevalent oncological disease among women. Various psychosocial distress is common at the diagnosis, treatment, and posttreatment phase of breast cancer. For the treatment of breast cancer, not only medical treatment but also psychosomatic integrative care will be needed. Patients with breast cancer may lead to increased vulnerability to stress, adjustment disorder, anxiety disorder, and depressive disorder, and these psychiatric diseases and conditions are associated with recurrence or exacerbation of breast cancer. Psychosocial treatment of anxiety and depression could increase the quality of life of patients and decrease the recurrence and progression of breast cancer. In this article, we reviewed 5 clinical breast cancer survivorship guidelines focused on psychosomatic integrative care including psychosocial treatment and alternative treatment for psychosocial distress. Because 5 treatment guidelines were using various definitions of evidence, we confirmed evidence of various psychosocial treatments for patients with breast cancer based on the definition of evidence by the US Preventive Service Task Force (USPSTF) guideline. We also reviewed the effect size of psychosocial treatment for anxiety, depression, mood, and quality of life in patients with breast cancer. This article discusses the barrier to the delivery of psychosomatic integrative care and suggests integrative care planning for breast cancer. Multi-disciplinary teams, patient's needs assessment, information technology support, patient and caregiver engagement, planned periodic monitoring of psychosocial distress by a psychosomatic specialist or consultation-liaison psychiatrist are recommended as key features of a psychosomatic integrated care plan.

• Journal of Life Science
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• v.31 no.7
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• pp.641-653
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• 2021

The purpose of this study was to confirm the antifungal activity, plant growth-promoting activity, and mineral solubilizing activity of 18 types of bacteria isolated purely from rhizosphere soil. The potential of isolates of the genus Bacillus and Pseudomonas as biocontrol agents was confirmed through the antifungal activity of these isolates. This activity has been determined to be due to various hydrolytic enzymes on the cell wall of plant pathogenic fungi and the production of siderophores in isolates. In addition, most of the isolates have been found to have aminocyclopropane-1-carboxylate deaminase production activity, indole-3-acetic acid production activity, and nitrogen fixation activity. These characteristics are believed to have a positive effect on root development, growth, and the productivity of crops via a reduction in the concentration of ethylene under conditions of environmental stress, to which plants are commonly exposed. In addition, on testing for the solubilizing activity of the isolates for phosphoric acid, silicon, calcium carbonate, and zinc, some isolates were found to have mineral solubilizing activities. Inoculation of these isolates during plant growth is expected to assist plant growth by converting nutrients necessary for growth into usable forms that can be absorbed by plants. The 18 isolated strains can be used as biocontrol agents due to their antifungal activity, plant growthpromoting activity, and mineral solubilizing activity.

• Journal of Marine Life Science
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• v.4 no.2
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• pp.91-95
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• 2019

The changes of plasma cortisol concentration to high water temperature on common carp, Cyprinus carpio were studied. 20℃, 24℃ and 28℃ groups showed significantly increased plasma cortisol levels until 6 hours, and decreased plasma cortisol levels after 24 hours. Cortisol levels of 20℃ and 24℃ groups decreased to values close to the cortisol content before the experiment. However, 32℃ group showed significantly increased plasma cortisol levels until 24 hours, and maintained plasma cortisol level until 48 hours. The Cumulative mortality rates of 20℃, 24℃ and 28℃ groups increased until 12 hours, and maintained until 48 hours. Cumulative mortality rate of 32℃ group increased continuously until the end of the experiment. Using the results of this study, it could be used as a method to confirm the risk of mass perish in a specific area through hormone analysis.

• Journal of Korean Philosophical Society
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• no.113
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• pp.61-92
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• 2016

In the Western civilization, the concept of culture has traditionally the meaning of education or forming the moral humanity. However, this meaning of culture has recently changed since the advent of cultural relativism which lays stress on the cultural diversity. The current meaning of culture lies in the ways of life, whatever they are. It indicates that culture has nothing to do with universal human nature and morality, as the new concept of culture is only based on the historical and contingent life-situations of people in the each special area. Against this current view of culture, this paper contends that culture and humanity(human nature) are closely connected with each other and that every culture is rooted in the universal human nature. So culture could have a great influence on humanity and forming of moral community. This thesis might be justified by Husserl's view on the philosophical culture of the ancient Greece. According to Husserl, the philosophy in the ancient Greece intended to realize the idea of true humanity and to build the moral community. Husserl's interpretation of the philosophical culture is based on his belief that philosophy as an ideal culture transcends the cultural diversity and historical contingency and strives for a universal human community, in which all mankind are harmonized and live well. The philosophical culture would -so Husserl- result in the moral community. Against this conception of the moral cultural community, could man argue that the idea of the moral community be an ideal dream which could not be realized considering the irrational and immoral character of community. However, this argument should be refuted, because it has overlooked the moral and open-minded character of culture with the feeling of solidarity.

• Journal of Life Science
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• v.28 no.11
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• pp.1386-1395
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• 2018

Over recent years, it has become evident that the central nervous system bidirectionally interacts with the gastrointestinal tract along the gut-brain axis. A series of preclinical studies indicate that the gut microbiota can modulate central nervous system function through a multitude of physiological functions. Polyphenols are ubiquitous plant chemicals included in foods such as fruits, vegetables, tea, coffee and wine, and their consumption is directly responsible for beneficial health effects due to antioxidant, anti-inflammatory, antimicrobial, immunomodulatory, anticancer, vasodilating, and prebiotic-like effects. There is increasing evidence that dietary polyphenol can contribute to beneficial effects in neuronal protection acting against oxidative stress and inflammatory injury as well as in cognitive functions. In this paper, we overview the neuroprotective role of dietary polyphenols especially focusing on the neuroinflammation and neurovascular function by interaction with the gut microbiome. Polyphenol metabolites could directly act as neurotransmitters crossing the blood-brain barrier and modulating the cerebrovascular system or indirectly modulating gut microbiota. In addition, evidence suggests that dietary polyphenols are effective in preventing and managing neurological disorders, such as age-related cognitive decline and neurodegeneration, through a multitude of physiological functions. Dietary polyphenols are increasingly envisaged as a potential nutraceuticals in the prevention and treatment of neurological disorders, because they possess the ability to reduce neuroinflammation, to improve memory and cognitive function and to modulate the gut microbiota.

• Journal of Life Science
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• v.29 no.9
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• pp.977-985
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• 2019

Aster yomena (Kitam.) Honda is an edible vegetable and perennial herb belonging to the Asteraceae family, and has been used for a long time for the prevention and treatment of various diseases. Although leaf extracts of A. yomena are known to have antioxidant and anti-inflammatory effects, accurate efficacy assessments are still inadequate. In this study, we investigated whether the antioxidant efficacy of ethanol extract of A. yomena leaf (EEAY) is correlated with the anti-inflammatory effect in RAW 264.7 macrophages. The results showed that EEAY significantly inhibited the hydrogen peroxide ($H_2O_2$)-induced growth inhibition in RAW 264.7 cells, which was associated with increased expression of nuclear factor erythroid 2-related factor-2 (Nrf2) and heme oxygenase-1 (HO-1). EEAY pretreatment also effectively prevented $H_2O_2$-induced reactive oxygen species generation and apoptosis through inhibition of caspase-3 activation and poly (ADP-ribose) polymerase degradation. Additionally, EEAY significantly increased the expression and production of interleukin-10, a representative anti-inflammatory cytokine, which was associated with increased expression of toll-like receptor 4 and myeloid differentiation factor 88 at transcriptional and translational levels. Furthermore, the increased production of nitric oxide (NO) by lipopolysaccharide was markedly abolished under the condition of EEAY pretreatment, and the inhibitory effect of NO production by EEAY was further increased by hemin, an HO-1 inducer. Overall, our results suggest that EEAY is able to activate the Nrf2/HO-1 signaling pathway to protect RAW 264.7 macrophages from oxidative and inflammatory stress.

• Journal of Life Science
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• v.29 no.2
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• pp.191-197
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• 2019

Parkinson's disease (PD) is a progressive neurodegenerative disease that mainly affects motor system with clinical features such as bradykinesia, rigidity, tremor and abnormal posture. PD is characterized by the death of dopaminergic neurons in the substantia nigra pars compacta, which is associated with accumulation of oxidative stress and dysregulation of intracellular signaling pathway. Quercetin-3-O-glucuronide (Q3GA), a major metabolite of quercetin, has been reported to have neuroprotective effects. In this study, we examined the neuroprotective effect of Q3GA against 1-methyl-4-phenyl pyridinium ($MPP^+$)-induced neurotoxicity of PD and the underlying molecular mechanisms in SH-SY5Y cells. MTT and LDH assay showed that Q3GA significantly decreased $MPP^+$-induced cell death, which is accompanied by a reduction in poly (ADP-ribose) polymerase (PARP) cleavage. Furthermore, it attenuated $MPP^+$-induced intracellular reactive oxygen species (ROS) with the reduction of Bax/ Bcl-2 ratio. Moreover, Q3GA significantly increased the phosphorylation of Akt and cAMP response element binding protein (CREB), but it has no effects on the phosphorylation of extracellular signal-regulated kinase (ERK). Taken together, these results demonstrate that Q3GA significantly attenuates $MPP^+$-induced neurotoxicity through ROS reduction and Akt/CREB signaling pathway in SH-SY5Y cells. Our findings suggest that Q3GA might be one of the potential candidates for the prevention and/or treatment of PD.