• 상하수도학회지
• /
• 제23권3호
• /
• pp.305-313
• /
• 2009

This paper provides a method for evaluating a residual life of water mains using a proportional hazard model(PHM). The survival time of individual pipe is defined as the elapsed time since installation until a break rate of individual pipe exceeds the Threshold Break Rate. A break rate of an individual pipe is estimated by using the General Pipe Break Model(GPBM). In order to use the GPBM effectively, improvement of the GPBM is presented in this paper by utilizing additional break data that is the cumulative number of pipe break of 0 for the time of installation and adjusting a value of weighting factor(WF). The residual lives and hazard ratios of the case study pipes of which the cumulative number of pipe breaks is more than one is estimated by using the estimated survival function. It is found that the average residual lives of the steel and cast iron pipes are about 25.1 and 21 years, respectively. The hazard rate of the cast iron pipes is found to be higher than the steel pipes until 20 years since installation. However, the hazard rate of the cast iron pipes become lower than the hazard rates of the steel pipes after 20 years since installation.

• 보험의학회지
• /
• 제3권1호
• /
• pp.219-232
• /
• 1986

A study on establishment of normal range of cardiothoracic ratio calculated from photofluorography film of chest by age and sex in a total of the 6,598 insureds was undertaken. The results were as follows: 1. In male group, the frequency distribution of cardiothoracic ratio was skewed weakly to the right in second decade, symmetrical in third and fourth decade, and was skewed weakly to the left in fifth and sixth decade; in female group, it was skewed weakly to the left in second, third and fourth decade, and was skewed weakly to the right in fifth and sixth decade. 2. On assumption that normal range of cardiothoracic ratio should comprise about 85% of all cardiothoracic ratios in each age group of both sexes, the sites of deviation from mean value of cardiothoracic ratio corresponding to maximum and minimum cardiothoracic ratio in the range of about 85% above mentioned were detected by statistical method on the frequency distribution of log tranformed cardiothoracic ratio, and $M{\pm}1.3$ sindicating normal range of cardiothoracic ratio was determined. In male group, normal range of cardiothoracic ratio determined by statistical method is 35-45%, 40-50%, 40-50%, 40-50% and 40-50% succesively in order from second to sixth decade; in female group, 40-50%, 40-50%, 40-50%, 45-55% and 45-55%.

• 한국작물학회:학술대회논문집
• /
• 한국작물학회 2022년도 추계학술대회
• /
• pp.17-17
• /
• 2022

Leaves are an important organism for photosynthesis and transpiration. The shape of leaf is crucial factor affecting plant architecture. V-shape leaf rolling is enhancing canopy photosynthesis by increasing the CO₂ penetration and the light capture by reducing the shadow between the leaves. Therefore, moderate leaf rolling is thought to more high grain yield per area than flat leaf. We investigated 278 KRICE_CORE accession's Adaxial Leaf Rolling Index (LRI) in first heading using the following equation. For each accession, genomic DNA was used for sequencing. We sequenced the genomics with ~8 X coverage to detect SNPS. Raw reads were aligned against the rice reference (IRGSP 1.0) for SNP identification and genotype calling. To generate genotype data for GWAS, SNPs were filtered with minor allele frequency 0.05. Finally, 841,134 high-quality SNPs were used for our GWAS. The significant threshold was -log10(P)>7.23. From the results, 2 significance SNP were detected. Considering the LD block of 250kbp, 60 candidate gene were selected including Hypothetical gene and Conserved gene. In this poster, we analyzed candidate gene affecting adaxial Leaf Rolling through single-trait GWAS.

• 한국작물학회:학술대회논문집
• /
• 한국작물학회 2022년도 추계학술대회
• /
• pp.243-243
• /
• 2022

Leaves are an important organism for photosynthesis and transpiration. The shape of leaf is crucial factor affecting plant architecture. V-shape leaf rolling is enhancing canopy photosynthesis by increasing the CO₂ penetration and the light capture by reducing the shadow between the leaves. Therefore, moderate leaf rolling is thought to more high grain yield per area than flat leaf. We investigated 278 KRICE CORE accession's Adaxial Leaf Rolling Index (LRI) in first heading using the following equation. For each accession, genomic DNA was used for sequencing. We sequenced the genomics with ~8 X coverage to detect SNPS. Raw reads were aligned against the rice reference (IRGSP 1.0) for SNP identification and genotype calling. To generate genotype data for GWAS, SNPs were filtered with minor allele frequency 0.05. Finally, 841,134 high-quality SNPs were used for our GWAS. The significant threshold was -log10(P) >7.23. From the results, 2 significance SNP were detected. Considering the LD block of 250kbp, 60 candidate gene were selected including Hypothetical gene and Conserved gene. In this poster, we analyzed candidate gene affecting adaxial Leaf Rolling through single-trait GWAS.

• 물과 미래
• /
• 제5권1호
• /
• pp.27-36
• /
• 1972

수공구조물의 계획이나 안전한 설계에 필요한 계획강우량으로서 확률강우량의 정확한 파악은 구조물의 내용년수와 결부시켜서 연구 검토되어야 할 문제라 생각되어 본 고에서는 국내 주요지점 가운데 3개지점(서울 부산 및 대구)의 24시간 이하의 강우량 자료를 기본자료로 취하여 해석한 내용이다. 본 연구의 주요내용을 약술하면 다음과 같다. 1. 기왕의 수문자료중 결측된 자료에 대한 보완 $\circled1$ Fourier Series Method. $\circled2$Trend Diagram Method $\circled3$ Mean Value Method. 상기 ${\circled1}{\circled2}{\circled3}$방법을 실시하여 산출한 치들 중에서 방화공학적인 면을 고려하여 최대치를 선택하여 결측된 자료를 보완하였다. 2. 자료의 통계치 산정 강우량자료를 Computer에 의하여 작은 것부터 크기 순위로 나열하고 이와같이 정리된 자료치를 log, $\sqrt{}, \sqrt[3]{}, \sqrt[4]과 $\sqrt[5]의 값으로 변환시켜 필요한 통계치를 산정하였다. 3. 분포형 검정과 최적분포형의 설정 $x^2-Test$에 의하여 분포형을 검정하고 자료의 기각을 행하여 이 결과에 의하여 최적분포형을 설정하였다. 4. 내용안전년수에 따르는 확률강우량 확률년(재현기간)과 내용안전년수와의 상관 관계를 고찰하여 내용안전년에 대한 확률강우량을 제시하였다. 결론적으로 지점별 및 강우계속 시간별로 강우량의 최적분포형을 선정하여 최적분포식을 설정하였다. 또한 안전율과 내용연수에 대한 확률강우량을 계산하여 표로서 제시하였다.제시하였다.했으며, 여러 가지 特殊染色法이 개발되어 사람의 染色體 하나 하나를 정확히 식별 할 수 있는 단계에 접어들게 되었다. 그중에서도 식별 할 수 있는 단계에 접어들게 되었다. 그중에서도 대표적인 것이 키나크린 螢光染色法(quinacrine fluorescence staining method)와 김자分染法(heat-giemsa staining method)이며 이들 방법을 통하면 染色體의 縱軸에 따라 특유한 明暗의 밴드 패턴(banding patterns)이 나타나게 되어, 사람만이 아니라 고등한 동물의 모든 染色體가 쉽게 同定이 된다는 것이다. 조파구간에는 초장에 큰 변이가 없었고 파종기가 늦어짐에 따라 짧아졌다. 초장의 신장속도는 파종기가 늦어짐에 따라 현저하게 빨라지고 특히 조생종이 만생종보다 더욱 가속적인 경향이었다. 따라서 최고초장과 최저초장과의 절대치의 차이는 조생종일수록 적고 만생종일수록 큰 격차를 보이었다. 6. 간직경에 있어서도 만생종은 일반적으로 조기파종할수록 굵고, 조생종과 중생종은 4월 25일 파종기가 가장 굵은 편이며 이보다 파종기가 지연 가늘어지는 경향이었다. 7. 간중은 품종의 조만생에 따라 약간의 차이는 있으나 대체로 적기(4월 25일~5월 15일)보다 조기 혹은 만기 파종하면 작아지나 파종기 이동에 따른 간중의 변화는 품종의 조만성에 따라 양상을 달리하여 조생종은 4월 25일 내외, 중생종은 4월 25일~5월 15일 내외, 만생종은 4월 5일~5월 15일 내외의 파종기에서 최고수량에 달하고 이후 직선적으로 감소하였다. 8. Brix 도는 품종에 따라 절대치가 다르며 또한 파종기가 5월 15일 이후로 늦어짐에 따라 직선적으로 감소되어 파종기(x)와 Brix 도(y) 간에 고도의 부상관관계를 볼 수 있었다. 9. 출수후 40~45일경의 절간부위별

• 한국사회복지학
• /
• 제37권
• /
• pp.1-31
• /
• 1999

실직자의 재취업 실태 및 실업기간에 관한 실증연구는 지난 수 십년간 실업(고용)보험의 연구에 있어 중요한 부분을 차지하여 왔지만, 우리나라에서는 이러한 주제에 관한 체계적 실증 연구가 매우 부족한 실정이다. 본 연구는 1996년 7월부터 1997턴 12월까지 18개월간 총 60,141명의 실업급여 수급권자 중 1997년 6월까지의 실업급여 수급권자 40,175명을 대상으로 생존분석의 Life table 분석과 Accelerated Failure Time 모델분석을 실시하여, 실직자 및 실업급여 관련 변수들이 실업탈피 기대기간(expected unemployment period)에 미치는 영향력을 측정 분석하였다. 생존분석결과 최장 실직기간까지 실업상태로 남아있는 수급권자들의 비율(누적생존율)이 64.83%나 되었다. Accelerated Failure Time 모델 중 Log-Normal Model에 의한 분석결과 교육수준과 상시근로자수를 제외한 대부분의 독립변수들이 재취업까지의 기대기간에 통계적으로 유의미한 영향력을 미치는 것으로 나타났다. 이러한 실종분석 결과를 바탕으로 고학력, 고임금을 받던 화이트칼라 노동자들에 대한 적극적 노동시장정책의 필요성과 지역 및 업종의 재취업여건 차이를 감안한 실업대책의 필요성을 제언하였으며, 실업급여의 제도적 변수가 나타내는 순수한 효과를 파악하기 위한 다각적인 후속연구의 필요성을 제기하였다.

• 환경영향평가
• /
• 제9권3호
• /
• pp.203-214
• /
• 2000

Health risk assessment is applied to streamlining LCA(Life Cycle Assessment) using Monte carlo simulation for probabilistic/stochastic exposure and risk distribution analysis caused by data variability and uncertainty. A case study was carried out to find benefits of this application. BTC(Benzene, Trichloroethylene, Carbon tetrachloride mixture alias) personal exposure cases were assumed as production worker(in workplace), manager(in office) and business man(outdoor). These cases were different from occupational retention time and exposure concentration for BTC consumption pattern. The result of cancer risk in these 3 scenario cases were estimated as $1.72E-4{\pm}1.2E+0$(production worker; case A), $9.62E-5{\pm}1.44E-5$(manger; case B), $6.90E-5{\pm}1.16E+0$(business man; case C), respectively. Portions of over acceptable risk 1.00E-4(assumed standard) were 99.85%, 38.89% and 0.61%, respectively. Estimated BTC risk was log-normal pattern, but some of distributions did not have any formal patterns. Except first impact factor(BTC emission quantity), sensitivity analysis showed that main effective factor was retention time in their occupational exposure sites. This case study is a good example to cover that LCA with probabilistic risk analysis tool can supply various significant information such as statistical distribution including personal/environmental exposure level, daily time activity pattern and individual susceptibility. Further research is needed for investigating real data of these input variables and personal exposure concentration and application of this study methodology.

• Journal of Hospice and Palliative Care
• /
• 제23권1호
• /
• pp.11-16
• /
• 2020

Purpose: D-dimer levels are known to be associated with poor outcomes in patients with various cancers, but their significance at the end of life remains unclear. This study investigated D-dimer levels as a prognostic indicator for terminal cancer patients in the last hours of life. Methods: The retrospective study was conducted at a palliative care unit of a tertiary cancer center, using a database to analyze the records of patients treated from January 1, 2010 to December 31, 2018. In total, 67 terminal cancer patients with available data on D-dimer levels were included. Patients' demographic data, clinical information, and laboratory values, including D-dimer levels, were collected. Survival was analyzed using the Kaplan-Meier method and the log-rank test. A Cox proportional-hazards model was used to identify prognostic factors of poor survival. Results: The most common site of cancer was the lung (32.8%) and the median survival time was 5 days. Most laboratory results, particularly D-dimer levels, deviated from the normal range. Patients with high D-dimer levels had a significantly shorter survival time than those with low D-dimer levels (4 days vs. 7 days; P=0.012). In the Cox regression analysis, only a high D-dimer level was identified as a predictor of a poor prognosis (hazard ratio, 1.83; 95% confidence interval, 1.09~3.07). Conclusion: Our results suggest that at the very end of life, D-dimer levels may serve as a prognostic factor for survival in cancer patients.

• Animal Bioscience
• /
• 제36권1호
• /
• pp.10-18
• /
• 2023

Objective: In this study, we aimed to position the Hungarian Merino among other Merinoderived sheep breeds, explore the characteristics of our sampled animals' genetic similarity network within the breed, and highlight single nucleotide polymorphisms (SNPs) associated with daily weight-gain. Methods: Hungarian Merino (n = 138) was genotyped on Ovine SNP50 Bead Chip (Illumina, San Diego, CA, USA) and positioned among 30 Merino and Merino-derived breeds (n = 555). Population characteristics were obtained via PLINK, SVS, Admixture, and Treemix software, within-breed network was analysed with python networkx 2.3 library. Daily weight gain of Hungarian Merino was standardised to 60 days and was collected from the database of the Association of Hungarian Sheep and Goat Breeders. For the identification of loci associated with daily weight gain, a multi-locus mixed-model was used. Results: Supporting the breed's written history, the closest breeds to Hungarian Merino were Estremadura and Rambouillet (pairwise F_ST values are 0.035 and 0.036, respectively). Among Hungarian Merino, a highly centralised connectedness has been revealed by network analysis of pairwise values of identity-by-state, where the animal in the central node had a betweenness centrality value equal to 0.936. Probing of daily weight gain against the SNP data of Hungarian Merinos revealed five associated loci. Two of them, OAR8_17854216.1 and s42441.1 on chromosome 8 and 9 (-log₁₀P>22, false discovery rate<5.5e-20) and one locus on chromosome 20, s28948.1 (-log₁₀P = 13.46, false discovery rate = 4.1e-11), were close to the markers reported in other breeds concerning daily weight gain, six-month weight, and post-weaning gain. Conclusion: The position of Hungarian Merino among other Merino breeds has been determined. We have described the similarity network of the individuals to be applied in breeding practices and highlighted several markers useful for elevating the daily weight gain of Hungarian Merino.

• 수산경영론집
• /
• 제46권3호
• /
• pp.103-118
• /
• 2015

The purpose of this paper is to discuss possibilities of applying growth curve models, such as Logistic, Log-Logistic, Log-Normal, Gompertz and Weibull, to three specific technology areas of Fishery Science and Technology in the process of measuring their technology level between Korea and countries with the state-of-the art level. Technology areas of hazard control of organism, environment restoration, and fish cluster detect were selected for this study. Expert panel survey was conducted to construct relevant panel data for years of 2013, 2016, and a future time of approaching the theoretical maximum technology level. The size of data was 70, 70 and 40 respectively. First finding is that estimation of shape and location parameters of each model was statistically significant, and lack-of-fit test using estimated parameters was statistically rejected for each model, meaning all models were good enough to apply for measuring technology levels. Second, three models other than Pearl and Gompertz seemed very appropriate to apply despite the fact that previous case studies have used only Gompertz and Pearl. This study suggests that Weibull model would be a very valid candidate for the purpose. Third, fish cluster detect technology level is relatively higher for both Korea and a country with the state-of-the-art among three areas as of 2013. However, all three areas seem to be approaching their limits(highest technology level point) until 2020 for countries with the state-of-the-art. This implies that Korea might have to speed up her research activities in order to catch up them prior to 2020. Final suggestion is that future study may better apply various and more appropriate models respectively considering each technology characteristics and other factors.