• 제목/요약/키워드: Leading variety

검색결과 359건 처리시간 0.03초

Autophagy-Is it a preferred route for lifespan extension?

  • Dwivedi, Meenakshi;Ahnn, Joo-Hong
    • BMB Reports
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    • 제42권2호
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    • pp.65-71
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    • 2009
  • Autophagy, which is a process of self eating, has gained interest in the past decade due to its both beneficial and controversial roles in various biological phenomena. The discovery of autophagy genes (ATG) in yeast has led to focused research designed to elucidate the mechanism and regulation of this process. The role of autophagy in a variety of biological phenomena, including human disease, is still the subject of debate. However, recent findings suggest that autophagy is a highly regulated process with both beneficial and negative effects. Indeed, studies conducted using various model organisms have demonstrated that increased autophagy leads to an extended lifespan. Despite these findings, it is still unknown if all pathways leading to extended lifespan converge at the process of autophagy or not. Here, an overview of modern developments related to the process of autophagy, its regulation and the molecular machinery involved is presented. In addition, this review focuses on one of the beneficial aspects of autophagy, its role in lifespan regulation.

존 갈리아노 패션쇼에 나타난 현대패션코디네이션 특성 (The Characteristics of Modern Fashion Coordination in the John Galliano's Fashion Show)

  • 진경옥
    • 복식
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    • 제55권6호
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    • pp.51-66
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    • 2005
  • Fashion is to emphasize the importance of total coordination in creating an image. Therefore, modern fashion is not the conformation of fixed beauty but it exist in the expressed form of the variety and the completion according to the individual's personality for the self image of the clothes, the hair and make-up, the accessories and the like. This study Is aimed at reviewing one of the tendency of modern fashion coordination and the characteristics of John Gallianos fashion work and there upon, analizing the characteristics of John Galliano's fashion show, who is one of the most leading fashion designer, by dividing them Into four categories in large: 1) The maximum effect of fashion image by make-up and hair style 2) Adventurous fashion coordination with daring decoration 3) Fascinating fashion coordination Harmonized with color 4) Enlargement in the concept of fashion coordination by experimental way of clothing

How to approach feeding difficulties in young children

  • Yang, Hye Ran
    • Clinical and Experimental Pediatrics
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    • 제60권12호
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    • pp.379-384
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    • 2017
  • Feeding is an interaction between a child and caregiver, and feeding difficulty is an umbrella term encompassing all feeding problems, regardless of etiology, severity, or consequences, while feeding disorder refers to an inability or refusal to eat sufficient quantities or variety of food to maintain adequate nutritional status, leading to substantial consequences, including malnutrition, impaired growth, and possible neurocognitive dysfunction. There are 6 representative feeding disorder subtypes in young children: infantile anorexia, sensory food aversion, reciprocity, posttraumatic type, state regulation, and feeding disorders associated with concurrent medical conditions. Most feeding difficulties are nonorganic and without any underlying medical condition, but organic causes should also be excluded from the beginning, through thorough history taking and physical examination, based on red-flag symptoms and signs. Age-appropriate feeding principles may support effective treatment of feeding difficulties in practice, and systematic approaches for feeding difficulties in young children, based on each subtype, may be beneficial.

임계노즐 유동에 미치는 노즐 곡률의 영향 (Effect of the Nozzle Curvature on Critical Flows)

  • 김재형;김희동;박경암
    • 유체기계공업학회:학술대회논문집
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    • 유체기계공업학회 2002년도 유체기계 연구개발 발표회 논문집
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    • pp.331-336
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    • 2002
  • Recently the critical nozzles with small diameter are being extensively used to measure mass flow in a variety of industrial fields and these have different configurations depending on operation condition and working gas. The curvature radius of the critical nozzle throat is one of the most important configuration factors promising a high reliability of the critical nozzle. In the present study, computations using the axisymmetric, compressible, Navier-Stokes equations are carried out to investigate the effect of the nozzle curvature on critical flows. The diameter of the critical nozzle employed is D=0.3mm and the radius of curvature of the critical nozzle throat is varied in the range from 1D to 3D. It is found that the discharge coefficient is very sensitive to the curvature radius(R) of critical nozzle, leading to the peak discharge coefficient at R = 2.0D and 2.5D, and that the critical pressure ratio increases with the curvature radius.

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줄기세포의 분화 결손으로 인한 노화와 암화 (Mal-differentiation of Stem Cells: Cancer and Ageing)

  • 이미옥;차혁진
    • KSBB Journal
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    • 제26권3호
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    • pp.183-188
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    • 2011
  • Adult stem cells, which have characteristic of self-renewal and multipotency, are specialized cell types, responsible for the tissue regeneration of the damaged tissue. Recent studies suggest that stem cells senescence (or stem cells' ageing) is closely associated with the variety of ageing-related phenotypes such as tissue atrophy, degenerative diseases and onset of cancers. During ageing, declining of stem cells function and subsequently occurring mal-differentiation of stem cells would be important to understand the biological process of development of ageing-related phenotypes such as tissue degenerations and cancers. This review focuses on the DNA damage stress as a cause of senescence of stem cells and their mal differentiation, which is closely link to defect of regeneration potentials and neoplastic transformation. Understanding of molecular mechanisms governingsuch events is likely to have important implications for developing novel avenues for balancing tissue homeostasis longer period of time, further leading to 'Healthy ageing'.

Autonomous Aero-Robot and Disaster Response

  • Inoue, Koichi;Nakanishi, Hiroaki
    • 한국산업안전학회:학술대회논문집
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    • 한국안전학회 2003년도 추계 학술논문발표회 논문집
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    • pp.3-16
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    • 2003
  • After a not-widely-known fact is revealed that Japan is a leading country in production and use of industrial unmanned helicopters, a kind of UAV. The voice command system and the autonomous flight control system with a variety of control algorithms including neural network, robust and adaptive control that have been developed in collaboration between Kyoto University and Yamaha Motor Co., and funded by the Ministry of Education and Science of Japan are described in some detail. Both already-proven and promising future applications of the autonomous unmanned helicopters are given.

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일체형 광섬유복합조가선(OPSW) 개발 구축 (Development of Integrated Composite Suspension wire with Optical Fiber)

  • 손영철;최현범;김병직;김영택;윤경진
    • 전기학회논문지
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    • 제60권6호
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    • pp.1122-1127
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    • 2011
  • The thesis here by shows that the extant suspension wire, which is stretched between electric poles to support a variety of communication wires, can be replaced by specially-redesigned cables called OPSW(Composite Suspension Wire with Optical Fiber) which have been devised for the first time in the world so that the functions of both communication and support can be united into one cable which is sure to be successfully installed on site, hence leading to outstanding effects that it can sharply reduce the load applied to electric poles as well as the cost of forthcoming constructions and that it can accordingly make a great contribution to the building of Smart Grid network.

IT자산 안전성과 정보보호 서비스가 정보보호 품질 및 만족도에 미치는 영향에 관한 실증연구 (An Empirical Approach to the Influence of IT Assets Security and Information Security Service on Information Security Qualify and Satisfaction)

  • 권순재;이건창;김창현
    • 한국경영과학회지
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    • 제32권2호
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    • pp.149-162
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    • 2007
  • In the era of the internet and ubiquitous computing, IS users are still facing a variety of threats. Therefore, a need of more tightened information security service increases unprecedentedly. In this sense, this study is aimed at proposing a new research model in which IT assets (i.e., network, system, and information influence) Security and Information Security Service (i.e., confidentiality, integrity, nonrepudiation, authentication) affect information security quality positively, leading to users' satisfaction eventually. To prove the validity of the proposed research model, PLS analysis is applied with valid 177 questionnaires. Results reveal that both IT assets Security and Information Security Service influence informations security qualify positively, and user satisfaction as well. From the results, it can be concluded that Korean government's recent orchestrated efforts to boost the IT assets Security and Information Security Service helped great improve the information security quality and user satisfaction.

On the dynamics of rotating, tapered, visco-elastic beams with a heavy tip mass

  • Zeren, Serkan;Gurgoze, Metin
    • Structural Engineering and Mechanics
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    • 제45권1호
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    • pp.69-93
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    • 2013
  • The present study deals with the dynamics of the flapwise (out-of-plane) vibrations of a rotating, internally damped (Kelvin-Voigt model) tapered Bernoulli-Euler beam carrying a heavy tip mass. The centroid of the tip mass is offset from the free end of the beam and is located along its extended axis. The equation of motion and the corresponding boundary conditions are derived via the Hamilton's Principle, leading to a differential eigenvalue problem. Afterwards, this eigenvalue problem is solved by using Frobenius Method of solution in power series. The resulting characteristic equation is then solved numerically. The numerical results are tabulated for a variety of nondimensional rotational speed, tip mass, tip mass offset, mass moment of inertia, internal damping parameter, hub radius and taper ratio. These are compared with the results of a conventional finite element modeling as well, and excellent agreement is obtained.

Streptomyces melanosporofaciens가 생산하는 새로운 항생물질 I. 생산균의 분류 . 동정 (New Antibiotics Produced by SEreptomyces mekmosporofaciens I. Taxonomy of the producing microorganism)

  • 김시관;김상석;김창한
    • 한국미생물·생명공학회지
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    • 제18권6호
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    • pp.624-632
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    • 1990
  • 새로운 phthalic acid 유도체 및 염기성 마크로라이드 항생물질을 생산하는 strain 88-GT-161은 numerical taxonomic data base에 의거 Streptomyces melanosporofaciens로 동정되었으나, 139 단위 특성 중 4가지 단위에 있어. S.violaceoniger 혹은 S.violaceusniger로 대표되는 cluster No.32에 속하는 6균주의 공통된 특성과 분명히 다른 특성을 나타냈다. 따라서 본 논문에서는 strain 88-GT-161의 분류. 동정학적 특성에 대하여 보고하고자 한다.

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