• 대한약침학회지
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• 제18권1호
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• pp.44-55
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• 2015

Objectives: Scolopendra subspinipes mutilans (S. subspinipes mutilans) is known as a traditional medicine and includes various amino acids, peptides and proteins. The amino acids in the pharmacopuncture extracted from S. subspinipes mutilans by using derivatization methods were analyzed quantitatively and qualitatively by using high performance liquid chromatography (HPLC) over a 12 month period to confirm its stability. Methods: Amino acids of pharmacopuncture extracted from S. subspinipes mutilans were derived by using O-phthaldialdehyde (OPA) & 9-fluorenyl methoxy carbonyl chloride (FMOC) reagent and were analyzed using HPLC. The amino acids were detected by using a diode array detector (DAD) and a fluorescence detector (FLD) to compare a mixed amino acid standard (STD) to the pharmacopuncture from centipedes. The stability tests on the pharmacopuncture from centipedes were done using HPLC for three conditions: a room temperature test chamber, an acceleration test chamber, and a cold test chamber. Results: The pharmacopuncture from centipedes was prepared by using the method of the Korean Pharmacopuncture Institute (KPI) and through quantitative analyses was shown to contain 9 amino acids of the 16 amino acids in the mixed amino acid STD. The amounts of the amino acids in the pharmacopuncture from centipedes were 34.37 ppm of aspartate, 123.72 ppm of arginine, 170.63 ppm of alanine, 59.55 ppm of leucine and 57 ppm of lysine. The relative standard deviation (RSD %) results for the pharmacopuncture from centipedes had a maximum value of 14.95% and minimum value of 1.795% on the room temperature test chamber, the acceleration test chamber and the cold test chamber stability tests. Conclusion: Stability tests on and quantitative and qualitative analyses of the amino acids in the pharmacopuncture extracted from centipedes by using derivatization methods were performed by using HPLC. Through research, we hope to determine the relationship between time and the concentrations of the amino acids in the pharmacopuncture extracted from centipedes.

• 대한임상검사과학회지
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• 제56권2호
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• pp.135-146
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• 2024

요검사는 검사실에서 일상적으로 수행되는 기본적인 검사이다. 연구에서 새로운 프로토콜을 포함한 두 가지 수동 현미경검사 방법을 표준화된 chamber 방법과 비교하였다. 시험지검사와 자동 침사물 분석기에서 적혈구 양성 201개와 백혈구 양성인 201개 검체로 구성된 총 402개 검체를 분석 대상으로 선정했다. 적혈구 및 백혈구에 대한 표준화된 chamber 방법과 새로운 프로토콜 방법 간의 상관계수는 모두 r=0.98로, 높은 수준의 상관관계를 나타냈다. 이 두 방법 간의 동일 등급에 대한 쌍별 일치율은 적혈구의 경우 86.1%, 백혈구의 경우 88.6%였으며, 한 등급 차이 내 일치율은 모두 99.5%였다. 반면, 표준화된 chamber 방법과 중·소규모 검사실 방법 간의 일치율은 적혈구의 경우 11.9%, 백혈구의 경우 13.4%로, 동일 등급 일치율이 현저히 낮았고, 한 등급 차이 내 일치율은 각각 67.2%와 74.1%로 나타났다. 급내상관계수 및 Bland-Altman plot을 사용한 분석에서는 새로운 프로토콜이 다른 세 가지 수동 현미경검사 방법에 비해 우수한 일치도를 보인 것으로 확인되었다. 표준화된 chamber 방법과의 높은 상관관계와 일치도를 고려해 볼 때, 새로운 프로토콜 방법을 소변 침사물 표본제작의 표준화된 절차로 권장한다.

• 한국산학기술학회논문지
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• 제15권7호
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• pp.4588-4594
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• 2014

본 연구에서는 연약지반에서의 경량콘크리트포장을 적용할 때의 안전성 평가를 위해 실제 포장체 사이즈의 1/30으로 축소한 모형을 이용하여 모래지반에서 실험을 실시하였다. 모형토조를 이용하여 지반을 조성하였고, 표준 말뚝재하시험(완속재하시험방법)을 이용하였다. 수직하중이 적용되는 말뚝기초의 슬래브의 중심에서 가까운 순으로 Case A, Case B, Case C로 구분하였고, 각각의 말뚝의 간격은 8cm로 하였다. 말뚝기초 모형시험결과 사질토지반에서 수직하중을 1.5kg에서 12kg로 증가시킬 때 포장체가 전체적으로 침하하였고, 최대 침하량은 0.4mm로 측정되었다. Case A의 경우 압축력을 받는 것으로 나타났으며, Case B는 수직하중이 증가함에 따라 말뚝에 압축력과 함께 인장력도 같이 받는 것으로 보이며, Case C는 하중단계가 증가할수록 인장변형이 증가하는 경향을 나타내었다.

• 한국지반신소재학회논문집
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• 제8권4호
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• pp.35-40
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• 2009

본 논문에서는 순환골재 다공질 콘크리트말뚝(RAPP : Recycled-Aggregate Porous Concrete Pile)에 의한 압밀촉진효과를 파악하기 위하여 일련의 실내모형실험을 수행하였다. 본 연구에서 얻어진 실험 결과를 동일한 조건에서 수행한 모래다짐말뚝과 쇄석다짐말뚝에 대한 기존의 실험결과(유승경, 2009)와 비교하여 RAPP로 개량된 복합지반의 시간에 따른 침하량의 변화 특성과 압밀시간에 대하여 비교, 분석하였다. 또한 일련의 수치해석을 수행하여 실내모형실험 결과를 평가하였다. 분석 결과로부터 RAPP에 의한 일차압밀과 이차압밀에 대한 침하저감효과가 타 공법에 비해 탁월함을 알 수 있었으며 압밀 종료시간도 상대적으로 빠르게 나타나 RAPP에 의한 압밀촉진효과가 우수함을 입증할 수 있었다.

• 한국입자에어로졸학회지
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• 제12권1호
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• pp.1-9
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• 2016

In this work, we evaluated the characteristics of flow field and uniformity of the nose-only exposure chambers for the inhalation toxicity test. Computational fluid dynamics (CFD) modeling was carried out to demonstrate uniformity of the nose-only exposure chambers. Because it is very important in the inhalation toxicity experiments that test materials are distributed uniformly to each holder of the chamber. The test was done with these 3 types of chamber with different form to develop inhalation toxicity evaluation system, easy-to-operate system among exposure chamber used for evaluating inhalation toxicity of environmental chemical mixtures. Through CFD interpretation, nose-only exposure chamber was made with the selection of the optimal conditions. For its evaluation, one type of fragrance was selected and measured particle size distribution of each port. The gene becoming luminous to green fluorescence was combined with GPT-SPE, a type of tGFP vector, to be inhaled to the mouse. Based on this, luminous intensity was checked. As a result, total particle number concentration of each port had average value of $3.17{\times}10^6{\sharp}/cm^3$ and range of the highest and lowest concentration value was approximately ${\pm}4.8%$. Autopsy of lung tissues of mouse showed that it had clearly better delivery of gene compared to the control group.

• ETRI Journal
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• 제24권6호
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• pp.435-442
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• 2002

Antenna Passive Intermodulation (PIM) level measurement results are rarely credited to be due to external signal receiving characteristics of the antennas or serious effects from external PIM sources, such as the anechoic chamber absorber and antenna tower. This paper presents an antenna PIM model for a reflected PIM measurement method. Based on the findings of null point generation and the behavior of the third order PIM values obtained by theoretical predictions and experimental results, we concluded that the results of the antenna PIM level test were influenced by the external PIM sources generated by the anechoic chamber absorber and the path differences of PIM signals coming into the antenna.

• Corrosion Science and Technology
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• 제2권5호
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• pp.207-211
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• 2003

The weather resistance of five coatings systems based on alkyd, chlorinated rubber, epoxy, polyurethane and fluoropolymer were studied by natural exposure test and accelerated test. The coatings were exposed at Hanoi station with urban industry atmosphere and at Baichay station with marine atmosphere. The degradation of coatings was evaluated by gloss measurement and surface analysis by scanning electronic microscopy. The results obtained show that among coatings tested the gloss of polyurethane and fluoropolymer coatings remained highly and those of alkyd, chlorinated rubber and epoxy coatings were very low after two years of atmospheric exposure. Under accelerating conditions the gloss of fluoropolymer coatings remained highly after 80 cycles of testing. By comparison with accelerating test in UV-condensation chamber the conditions at atmospheric stations are more aggressive.

• 한국지반신소재학회논문집
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• 제7권2호
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• pp.23-29
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• 2008

본 연구의 목적은 연약지반개량을 위한 다짐말뚝공법의 재료로써 건설폐기물에서 선별 처리된 순환골재의 적용성을 평가함과 동시에 기존 다짐말뚝공법들의 단점을 보완하는 새로운 공법을 개발하는 데 있다. 본 논문에서는 순환골재 다공질 콘크리트말뚝에 의한 지반개량효과를 분석하기 위하여 실내모형실험을 수행하였다. 실험결과로부터 개량된 복합지반의 침하량과 과잉간 극수압 및 연직응력증분의 시간에 따른 변화 특성과 복합지반의 거동 특성을 분석하였다.

• 대한의용생체공학회:의공학회지
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• 제39권5호
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• pp.175-182
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• 2018

The purpose of this study is to evaluate the reliability and effectiveness of hyperbaric oxygen chamber on alcohol-induced oxidative stress and hangover. In order to evaluate them, 20 healthy adults were tested for blood and hangover stress tests. When an exponential change was examined after 3 interventions (hangover drink, hyperbaric oxygen chamber, and normal chamber as placebo effect) of 1 hour, the heart rate of subjects experiencing a hyperbaric oxygen chamber showed a statistically significant decrease (p < 0.001). The tests of blood alcohol concentration (BAC) as for exquisite hematology analysis, glucose, creatinine, and AST (aspartate aminotransferase) as well as ALT (alanine aminotransferase) used as liver-damage indicator show that the hyperbaric chamber has the effective effect. In the test of lactic acid, CRP (c-reactive protein), cortisol, and creatinine, the hyperbaric chamber shows much more excellent effect than the hangover drink and normal chamber as control groups. Further studies on hyperbaric oxygen chamber intervention including this study could be very helpful for improving lives of both the patients and healthy people.

• 비파괴검사학회지
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• 제13권3호
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• pp.31-38
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• 1993

포항가속기 저장링 진공챔버는 진공도가 $10^{-10}Torr$로 유지될 수 있도록 설계되었고, 초고진공에 적합하도록 TIG용접을 하여 헬륨에 대한 누설률이 $1{\times}10^{-10}Torr{\cdot}{\ell}/sec$ 이하의 기밀성이 요구되고 있다. 저장링 진공챔버에 적용된 TIG용접방법과 결함에 대해 논하고 누설검사에 사용된 헬륨누설검사기의 원리 및 검사방법에 대해서 보고하고자 한다.