• 한국동물번식학회:학술대회논문집
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• 한국동물번식학회 2002년도 춘계학술발표대회 발표논문초록집
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• pp.18-18
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• 2002

This study was to investigate the effect of neurotrophic factors on neural cell differentiation in vitro derived from human embryonic stem (hES, MB03) cells. For neural progenitor cell formation derived from hES cells, we produced embryoid bodies (EB: for 5 days, without mitogen) from hES cells and then neurospheres (for 7 - 10 days, 20 ng/㎖ of bFGF added N2 medium) from EB. And then finally for the differentiation into mature neuron cells, neural progenitor cells were cultured in ⅰ) N2 medium (without bFGF), ⅱ) N2 supplemented with brain derived neurotrophic factor (BDNF, 5ng/㎖) or ⅲ) N2 supplemented with platelet derived growth factor-bb (PDGF-bb, 20ng/㎖) for 2 weeks. (omitted)

• Journal of Dairy Science and Biotechnology
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• 제27권1호
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• pp.37-43
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• 2009

The mammalian immune system comprises a complex array of cells and molecules that interact to provide protection from pathogenic microorganisms. The beneficial role played by lactic acid bacteria and milk-derived peptides in humans, including their effect on the immune system, has been extensively reported. Lactic acid bacteria and milk-derived peptides, which are present in dairy products, are frequently used as nutraceuticals to improve some biological functions in the host. Activation of the systemic and secretory immune response by lactic acid bacteria and milk-derived peptides requires many complex interactions among the various constituents of the intestinal ecosystem. Thus, the aim of this review was to examine in detail the immunological potential of lactic acid bacteria and milk-derived peptides.

• BMB Reports
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• 제31권2호
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• pp.156-160
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• 1998

In this study, we cultured bovine capillary endothelial cells from adrenal cortex and compared these cells with capillary endothelial cells obtained from bovine adrenal medulla on morphological and cytokinetic properties. We demonstrated that bFGF and gelatin matrix were required for the growth of adrenal cortex-derived capillary endothelial cells over middle passage, but not for the growth of adrenal medulla-derived capillary endothelial cells. Also, we showed that the growth of adrenal cortex-derived capillary endothelial cells must be stimulated by bFGF and the gelatin matrix for the measurement of in vitro angiostatin activity. These data indicate that adrenal cortex-derived capillary endothelial cells over middle passage are more suitable than adrenal medulla-derived capillary endothelial cells for in vitro angiogenesis assay.

• Journal of Electrochemical Science and Technology
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• 제15권1호
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• pp.111-131
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• 2024

Lignin-derived porous carbon has been identified as a versatile electrode material for supercapacitors (SCs) in energy storage systems (ESSs) owing to their intrinsic advantages including good electrical conductivity, low cost, high thermal and chemical stability, and high porosity, which stem from high surface, appropriate pore distribution, tailored morphologies, heterostructures, and diverse derivates. In this review, to provide a fundamental understanding of the properties of lignin, we first summarize the origin, historical development, and basic physicochemical properties. Next, we describe essential strategies for the preparation of lignin-derived porous carbon electrode materials and then highlight the latest advances in the utilization of lignin-derived porous carbon materials as advanced electrode materials. Finally, we provide some of our own insights into the major challenges and prospective research directions of lignin-derived porous carbon materials for supercapacitors. We believe that this review will provide general guidance for the design of next-generation electrode materials for supercapacitors.

• Journal of Radiation Protection and Research
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• 제19권3호
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• pp.199-208
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• 1994

한국 환경을 고려하여 개발된 동적 섭식경로 모델을 이용하여 한국인이 섭취하는 음식물에 대한 유도개입준위를 산정하였다. 섭식경로에 있어 중요한 피폭효과를 가지는 I-131은 유아의 갑상선에 대한 예탁선량당량에 대해, Cs-137과 Sr-90은 전신에 대한 예탁선량당량에 근거한 선량개입준위로부터 연령군별로 13개 음식물에 대해 유도개입준위를 산정하였다. 성인은 Cs-137과 Sr-90의 음식물에 대한 유도개입준위 산정에 있어 가장 중요한 연령 군으로 평가되었다. 성인의 경우 쌀에서 Cs-137과 Sr-90의 유도개입준위는 여름철 침적의 경우 각각 2390, 47 Bq/kg, 겨울철 침적의 경우 각각 198, 79 Bq/kg으로 침적시점과 핵종에 따라 매우 다른 값의 변화를 보여주었다.

• 한국수정란이식학회지
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• 제14권1호
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• pp.39-46
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• 1999

To establish the optimal culture systems for production of transferable embryos in Korean Cattle, pregnancy rates of IVF-derived blastocysts according to different culture media, culture method and culture duration were compared. Development of IVF-derived embryos to blastocysts was most effective in YS medium group co-cultre with cumulus cells. Blastocysts cultured for 6 to 8 d in vitro showed higher hatching rate and good quality. Pregnancy rates after transfer of IVF-derived blastocysts cultured for 7 or 8 d were high. Through our experiments, it is considered that improvement of culture media and culture method is necessary for mass production of blastocysts with excellent of good quality in Korean Cattle.

• 한국언어정보학회:학술대회논문집
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• 한국언어정보학회 2001년도 학술대회 논문집
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• pp.25-58
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• 2001

This study explores the lexical-semantic structure of derived causative verbs in Korean based on Pustejovsky(1995)'s Generative Lexicon Theory (GL), Mor-phological causative verbs are derived from their root stems by affixing ‘-i, -hi, -li, -gi’ in Korean and the meanings of derived predicates are closely related to the meanings of their root verbs. In particular, the change of the ARGUMENT STRUCTURE by morphological derivation leads to the change of the EVENT STRUCTURE. In this study, causation is defined as the cause-effect relation having a causer. The ARGUMENT STRUCTURES of derived causative verbs includes a causer argument, which is added to the ARGUMENT STRUCTURE of their root verbs. Their EVENT STRUCTURE has a headed process related to a causer and their result is the event which their root verbs represent. This approach can also suggest that the (in)directness of causative is determined by which verb is its root and explain the difference between the morphological causativization and the syntactic causativization in Korean.

• 한국언어정보학회지:언어와정보
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• 제6권2호
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• pp.57-82
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• 2002

This study explores the lexical-semantic structure of derived causative verbs in Korean based on Pustejovsky(1995)'s Generative Lexicon Theory (GL). Morphological causative verbs are derived from their root stems by affixing ‘-i, -hi, -li, -gi’ in Korean and the meanings of derived predicates are closely related to the meanings of their root verbs. In particular, the change of the ARGUMENT STRUCTURE by morphological derivation leads to the change of the EVENT STRUCTURE. The ARGUMENT STRUCTURES of derived causative verbs include a causer argument, which is added to the ARGUMENT STRUCTURE of their root verbs by means of the causative derivation. Their EVENT STRUCTURE has a headed process related to a causer and its result is the event which their root verbs denote. This approach can also suggest that the (in)directness of causative is dependent on is the semantics of its root verb.

• BMB Reports
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• 제48권2호
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• pp.103-108
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• 2015

Trichomoniasis caused by the parasitic protozoan Trichomonas vaginalis is the most common sexually transmitted disease in the world. Dendritic cells are antigen presenting cells that initiate immune responses by directing the activation and differentiation of naive T cells. In this study, we analyzed the effect of Trichomonas vaginalis-derived Secretory Products on the differentiation and function of dendritic cells. Differentiation of bone marrow-derived dendritic cells in the presence of T. vaginalis-derived Secretory Products resulted in inhibition of lipopolysaccharide-induced maturation of dendritic cells, down-regulation of IL-12, and up-regulation of IL-10. The protein components of T. vaginalis-derived Secretory Products were shown to be responsible for altered function of bone marrow-derived dendritic cells. Chromatin immunoprecipitation assay demonstrated that IL-12 expression was regulated at the chromatin level in T. vaginalis-derived Secretory Products-treated dendritic cells. Our results demonstrated that T. vaginalis- derived Secretory Products modulate the maturation and cytokine production of dendritic cells leading to immune tolerance.

• BMB Reports
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• 제29권6호
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• pp.549-554
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• 1996

Phosphoinositide turnover in response to platelet-derived growth factor, epidermal growth factor, and bradykinin was evaluated in NIH 3T3 cells. Platelet-derived growth factor and bradykinin induced a significant increase in incorporation of $^{32}P$ into phosphatidylinositol (PI), phosphatidylinositol 4-monophosphate (PIP), and phosphatidylinositol 4.5-bisphosphate ($PIP_2$) in serum-starved NIH 3T3 cells. However, epidermal growth factor increased incorporation of $^{32}P$ into these phosphoinositides by only a small amount. Stimulation with platelet-derived growth factor, not bradykinin, caused a rapid elevation of PI and PIP kinase activities that were maximally activated within 10 min. The maximal levels of their elevation in cells with plateletderived growth factor stimulation were 3.2-fold for PI kinase, and 2.1-fold for PIP kinase. Short term pretreatment of NIH 3T3 cells with phorbol 12-myristate 13-acetate, activator of protein kinase C. caused an approximately 60% decrease in platelet-derived growth factor-induced PI kinase activities, indicating the feedback regulation of phosphoinositide turnover by protein kinase C. These results suggest that although the enhancement of phosphoinositide turnover is a rapidly occurring response in platelet-derived growth factor- or bradykinin-stimulated NIH 3T3 cells, phosphoinositide kinases may be associated with initial signal transduction pathway relevant to platelet-derived growth factor but not to bradykinin.