• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 1997년도 춘계학술대회논문집; 경주코오롱호텔; 22-23 May 1997
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• pp.506-512
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• 1997

Ultrasonic knives have been successfully used for the surgery of many medical fields. However, the conventional ultrasonic knives for surgical operation cannot be controlled its resonant frequency. So if the material to cut has different characteristic impedance then different ultrasonic knife will be needed. Because the optimum driving frequency of ultrasonic knife is different by characteristic impedance of material. In this work, using a frequency variable ultrasonic transducer made of multi-layered PZT vibrator, a frequency controllable ultrasonic knife will be suggested. The design and computation principles will be also derived. For this work, firstly, the characteristics of this ultrasonic knife will be analyzed by transmission line model equivalent circuit, and the free admittance characteristics and vibrational velocity distributions will be obtained. Secondly, we will design and make the frequency controllable electrical oscillator for driving this ultrasonic knife.

• 한국신뢰성학회지:신뢰성응용연구
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• 제15권4호
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• pp.270-275
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• 2015

Purpose : UHMWPE (Ultra-high-molecular-weight-polyethylene) is one of the most widely used material in knife protection clothes because of high strength, elasticity, and light weight. The purpose of this study is to develop the accelerated life test method and predict the lifetime for the knife protection fabric composed by UHMWPE. Methods : In this study, degradation characteristics of UHMWPE fibers and knife protection fabric for cut resistance were evaluated under the hydrolysis and photo-degradation conditions. It was found out that the degradation rate of retained tensile strength was more significant in the photo-degradation than hydrolysis. Therefore, the failure time was determined as the time that the retained tensile strength in photo-degradation is less than 50%. Considering an acceleration factor for irradiance and exposure time, the lifetime was predicted from the calculated failure time. Results : As a result of the accelerated life test, the $B_{10}$ lifetime of knife protection fabric composed by UHMWPE fibers is estimated as 2.8 years for a 90% statistical confidence level. Conclusion: Since the lifetime is predicted by the view-point of radiant exposure in this study, there is a possibility that the estimated lifetime may differ from the actual lifetime. However, it is considered as an useful methodology to estimate the long-term lifetime of knife protection fabrics.

• 대한방사선치료학회지
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• 제9권1호
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• pp.50-55
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• 1997

The optimal management of uveal melanoma is still a matter of controversy. To determine the effect of Gamma Knife surgery for patients with uveal malanoma. the authors reviewed the results of 5 patients underwent Gamma Knife sugery between Sep. 1993 and Dec. 1996. The mean age was 60.7 years ranging from 42.5 to 76.5 years. Median follow-up was 13.29 months and the patient with follow up period more than 6 months was 4. The mean tumor volume was $3442 mm^3$(mean diameter 15.3 mm) and all patients were irradiated with a mean maximum dose of 74Gy(range $60\~80\;Gy$), using the $50\%$ isodose. After Gamma Knife surgery. one pateint showed complete disapperance in tumor size with follow-up 32 months, one enucleation due to progression, and 2 no interval change. In regard to vision, one patient blind. one enucleation, and 2 patients had no interval change. According to our experiences, Gamma Knife surgery for uveal melanoma be able to achieve local tumor control, spare the eyeball, and have possibility of save vision.

• Journal of International Society for Simulation Surgery
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• 제2권2호
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• pp.58-63
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• 2015

Image-guided neurosurgery (IGN) is a technique for localizing objects of surgical interest within the brain. In the past, its main use was placement of electrodes; however, the advent of computed tomography has led to a rebirth of IGN. Advances in computing techniques and neuroimaging tools allow improved surgical planning and intraoperative information. IGN influences many neurosurgical fields including neuro-oncology, functional disease, and radiosurgery. As development continues, several problems remain to be solved. This article provides a general overview of IGN with a brief discussion of future directions.

• Journal of Biosystems Engineering
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• 제20권1호
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• pp.3-12
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• 1995

This study was conducted to investigate the cutting mechanism of the reciprocating knife of combine harvester. The cutting operation of reciprocating knife was demonstrated through the cutting pattern diagram which was drawn by computer graphics. Various kinds and dimensions of standard-type reciprocating knives were analyzed by the developed program. The results are summarized as follows : (1) For the 50mm standard reciprocating knife, the bunching area and the maximum stalk-deflection were decreased rapidly according to the increase of cutting velocity ratio by 1.0 and decreased very slowly over this ratio. But, the secondary cut was occurred at ratio of 1.0 and increased rapidly over this ratio. (2) The 76mm standard knife showed better cutting mechanism than the 50mm, in two respects : the larger cutting area per one stroke and the lower revolutional speed of crank shaft for the same cutting velocity. (3) In respect to the bunching area and the secondary cutting length, the adequate height of 50mm standard reciprocating knife was 45~50mm. (4) In order to maintain the proper cutting mechanism, the adequate cutting velocity at forward speed of 0.5㎧ to 1.2m/s was from 0.4m/s to 1.2m/s for the standard knife.

• 한국의학물리학회지:의학물리
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• 제29권4호
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• pp.115-122
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• 2018

Although the current internationally recommended standard for the use factor (U) applied to CyberKnife is 0.05 (5%), the CyberKnife shielding standard is applied more stringently. This study, based on clinical data, was aimed at examining the appropriateness of existing shielding guidelines. Sixty patients treated with G4 CyberKnife were selected. The patients were divided into two groups, according to whether they underwent skull or spine tracking. Based on the results, the use factors for each wall ranged from 0.028 (2.8%) to 0.031 (3.1%) for the intracranial treatment and 0.020 (2.0%) to 0.022 (2.2%) for the body treatment. Excessive barrier thickness resulted in inefficient use of space and higher cost to the institutions. Furthermore, because the use factor is influenced by the position of the robot, the use factor determined based on the clinical data of this study would facilitate more reasonable treatment room design.

• 한국의학물리학회지:의학물리
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• 제18권4호
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• pp.194-201
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• 2007

감마나이프는 한 번에 수 Gy의 선량을 조사하는 일반 방사선 치료에 비하여 훨씬 많은 수십 Gy의 고선량을 한 번에 조사하기 때문에 조사되는 방사선량의 절대값 측정이 매우 중요하다. 그러나, 감마나이프의 물흡수선량 절대 측정값을 검증하는 연구는 많지 않다. 더욱이, 물팬텀 사용을 규정한 국제원자력기구(International Atomic Energy Agency: IAEA) TRS-398 프로토콜을 적용하여 물흡수선량을 측정한 연구는 보고되고 있지 않다. 본 연구에서는 IAEA TRS- 398 프로토콜을 이용하여 감마나이프 C모델의 물흡수선량을 측정하는 실험을 하였다. 본 실험에서는 IAEA TRS-398에 규정한 바를 최대한 따르면서 물팬텀을 제작하여 감마나이프 C모델의 물흡수선량을 측정하고, 감마나이프 제작사에서 제공하는 플라스틱 팬텀에서 측정한 값과 비교하였다. 이온함으로는 Capintec 사의 PR-05P mini-chamber 두 개를 사용하였고, 전리계로는 PTW사의 UNIDOS를 사용하였다. 측정 결과 물팬텀에서 측정한 감마나이프 모델C의 물흡수선량은 제작사의 플라스틱팬텀에서 측정한 값에 비하여 1.38% 크게 나타났다- 따라서, 현재 국내 감마나이프센터에서 사용하고 있는 제작사에서 제공하고 물흡수선량 측정 프로토콜에는 물팬텀 대신 플라스틱팬텀을 사용하는 데 따른 기온적인 문제점이 있는 것으로 판단된다. 결론적으로 IAEA TRS-398프로토콜을 직접적으로 감마나이프 물흡수선량 측정에 적용하는 것은 기준조건을 만족시킬 수 없기 때문에 불가능한 것으로 판단되며, 새로운 프로토콜을 작성하거나, 물팬텀과 기존의 플라스틱 팬텀으로 측정한 값 사이의 변환계수를 제공하는 것이 현실적인 대안이 될 것이다.

• Radiation Oncology Journal
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• 제33권3호
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• pp.233-241
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• 2015

Purpose: To compare volumetric modulated arc therapy of RapidArc with robotic stereotactic body radiation therapy (SBRT) of CyberKnife in the planning and delivery of SBRT for hepatocellular carcinoma (HCC) treatment by analyzing dosimetric parameters. Materials and Methods: Two radiation treatment plans were generated for 29 HCC patients, one using Eclipse for the RapidArc plan and the other using Multiplan for the CyberKnife plan. The prescription dose was 60 Gy in 3 fractions. The dosimetric parameters of planning target volume (PTV) coverage and normal tissue sparing in the RapidArc and the CyberKnife plans were analyzed. Results: The conformity index was $1.05{\pm}0.02$ for the CyberKnife plan, and $1.13{\pm}0.10$ for the RapidArc plan. The homogeneity index was $1.23{\pm}0.01$ for the CyberKnife plan, and $1.10{\pm}0.03$ for the RapidArc plan. For the normal liver, there were significant differences between the two plans in the low-dose regions of $V_1$ and $V_3$. The normalized volumes of $V_{60}$ for the normal liver in the RapidArc plan were drastically increased when the mean dose of the PTVs in RapidArc plan is equivalent to the mean dose of the PTVs in the CyberKnife plan. Conclusion: CyberKnife plans show greater dose conformity, especially in small-sized tumors, while RapidArc plans show good dosimetric distribution of low dose sparing in the normal liver and body.

• Journal of Korean Neurosurgical Society
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• 제50권3호
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• pp.179-184
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• 2011

Objective : The aim of this study is to evaluate the therapeutic effects of gamma knife radiosurgery (GKRS) in patients with multiple brain metastases and to investigate prognostic factors related to treatment outcome. Methods : We retrospectively reviewed clinico-radiological and dosimetric data of 36 patients with 4-14 brain metastases who underwent GKRS for 264 lesions between August 2008 and April 2011. The most common primary tumor site was the lung (n=22), followed by breast (n=7). At GKRS, the median Karnofsky performance scale score was 90 and the mean tumor volume was 1.2 cc (0.002-12.6). The mean prescription dose of 17.8 Gy was delivered to the mean 61.1% isodose line. Among 264 metastases, 175 lesions were assessed for treatment response by at least one imaging follow-up. Results : The overall median survival after GKRS was $9.1{\pm}1.7$ months. Among various factors, primary tumor control was a significant prognostic factor ($11.1{\pm}$1.3 months vs. $3.3{\pm}2.4$ months, p=0.031). The calculated local tumor control rate at 6 and 9 months after GKRS were 87.9% and 84.2%, respectively. Paddick's conformity index (>0.75) was significantly related to local tumor control. The actuarial peritumoral edema reduction rate was 22.4% at 6 months. Conclusion : According to our results, GKRS can provide beneficial effect for the patients with multiple (4 or more) brain metastases, when systemic cancer is controlled. And, careful dosimetry is essential for local tumor control. Therefore, GKRS can be considered as one of the treatment modalities for multiple brain metastase.

• Corrosion Science and Technology
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• 제9권6호
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• pp.239-246
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• 2010

When galvanized steel strip is produced through a continuous hot-dip galvanizing process, the thickness of the adhered zinc film is controlled by impinging a thin plane nitrogen gas jet. The thickness of the zinc film is generally affected by impinging pressure distribution, its gradient and shearing stress at the steel strip. These factors are influenced by static pressure of gas spraying at air knife nozzle, a nozzle-to-strip distance and strip and a geometric shape of the air knife, as well. At industries, galvanized steel strip is produced by changing static pressure of gas and a distance between the air knife nozzle and strip based on experimental values but remaining a geometric shape of nozzle. Splashing and check-mark strain can generally occur when a distance between the air knife nozzle and strip is too short, while ability of zinc removal can lower due to pressure loss of impinging jet when a distance between the air knife nozzle and strip is too long. In present study, buckling of the jet and change of static pressure are observed by analyzing flow characteristics of the impinging jet. The distance from the nozzle exit to the strip varies from 6 mm to 16 mm by an increment of 2 mm. Moreover, final coating thickness with change of a distance between the air knife nozzle and strip is compared with each case. An ability of zinc removal with the various distances is predicted by numerically calculating the final coating thickness.