• Bulletin of the Korean Mathematical Society
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• v.49 no.1
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• pp.175-195
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• 2012

Representing planar Pythagorean hodograph (PH) curves by the complex roots of their hodographs, we standardize Farouki's double cubic method to become the undetermined junction point (UJP) method, and then prove the generic existence of solutions for general $C^1$ Hermite interpolation problems. We also extend the UJP method to solve $C^2$ Hermite interpolation problems with multiple PH cubics, and also prove the generic existence of solutions which consist of triple PH cubics with $C^1$ junction points. Further generalizing the UJP method, we go on to solve $C^2$ Hermite interpolation problems using two PH quintics with a $C^1$ junction point, and we also show the possibility of applying the modi e UJP method to $G^2[C^1]$ Hermite interpolation.

• Journal of the Korean Society of Industry Convergence
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• v.24 no.4_1
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• pp.411-419
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• 2021

In this study, IGBT_Total_Loss and DIODE_Total_Loss were used to analyze the slope of the junction temperature for each section for temperature and duty variables in order to simply calculate the junction temperature of the power semiconductor (IGBT). As a result of the calculation, IGBT_Max_Junction_Temp and DIODE_Max_Junction_Temp form a proportional relationship with temperature for each duty. This simulation data shows that the power loss of a power semiconductor is calculated in a complex manner according to the current dependence index, voltage dependence index, and temperature coefficient. By applying the slope for each condition and section, the junction temperature of the power semiconductor can be calculated simply.

• The Korean Journal of Pain
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• v.28 no.4
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• pp.231-235
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• 2015

Damage to peripheral nerves or the spinal cord is often accompanied by neuropathic pain, which is a complex, chronic pain state. Increasing evidence indicates that alterations in the expression and activity of gap junction channels in the spinal cord are involved in the development of neuropathic pain. Thus, this review briefly summarizes evidence that regulation of the expression, coupling, and activity of spinal gap junction channels modulates pain signals in neuropathic pain states induced by peripheral nerve or spinal cord injury. We particularly focus on connexin 43 and pannexin 1 because their regulation vastly attenuates symptoms of neuropathic pain. We hope that the study of gap junction channels eventually leads to the development of a suitable treatment tool for patients with neuropathic pain.

• BMB Reports
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• v.56 no.12
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• pp.625-632
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• 2023

Nonsense-mediated mRNA decay (NMD) is both a quality control mechanism and a gene regulation pathway. It has been studied for more than 30 years, with an accumulation of many mechanistic details that have often led to debate and hence to different models of NMD activation, particularly in higher eukaryotes. Two models seem to be opposed, since the first requires intervention of the exon junction complex (EJC) to recruit NMD factors downstream of the premature termination codon (PTC), whereas the second involves an EJC-independent mechanism in which NMD factors concentrate in the 3'UTR to initiate NMD in the presence of a PTC. In this review we describe both models, giving recent molecular details and providing experimental arguments supporting one or the other model. In the end it is certainly possible to imagine that these two mechanisms co-exist, rather than viewing them as mutually exclusive.

• BMB Reports
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• v.51 no.3
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• pp.157-162
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• 2018

Angiogenesis is a complex, multistep process involving dynamic changes in endothelial cell (EC) shapes and behaviors, especially in specialized cell types such as tip cells (with active filopodial extensions), stalk cells (with less motility) and phalanx cells (with stable junction connections). The Hippo-Yes-associated protein (YAP)/ transcription activator with PDZ binding motif (TAZ) signaling plays a critical role in development, regeneration and organ size by regulating cell-cell contact and actin cytoskeleton dynamics. Recently, with the finding that YAP is expressed in the front edge of the developing retinal vessels, Hippo-YAP/TAZ signaling has emerged as a new pathway for blood vessel development. Intriguingly, the LATS1/2-mediated angiomotin (AMOT) family and YAP/TAZ activities contribute to EC shapes and behaviors by spatiotemporally modulating actin cytoskeleton dynamics and EC junction stability. Herein, we summarize the recent understanding of the role of Hippo-YAP/TAZ signaling in the processes of EC sprouting and junction maturation in angiogenesis.

• Nuclear Engineering and Technology
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• v.41 no.9
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• pp.1191-1204
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• 2009

In this study, a CFD methodology is employed to address the problem of the prediction of the flow in a T-junction. An Unsteady Reynolds Averaged Navier-Stokes (URANS) approach has been selected for its low computational cost. Moreover, Unsteady Reynolds Navier-Stokes methodologies do not need complex boundary formulations for the inlet and the outlet such as those required when using Large Eddy Simulation (LES) or Direct Numerical Simulation (DNS). The results are compared with experimental data and an LES calculation. In the past, URANS has been tried on T-junctions with mixed results. The biggest limit observed was the underestimation of the oscillatory behavior of the temperature. In the present work, we propose a comprehensive approach able to correctly reproduce the root mean square (RMS) of the temperature directly downstream of the T-junction for cases where buoyancy is not present.

• 한국정보통신설비학회:학술대회논문집
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• 2009.08a
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• pp.36-39
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• 2009

We developed an optimal design interface based on VBA(Visual Basic Application) that takes advantage of API(Application Program Interface) function of commonly used EM analysis software. The developed interface is adopted for an optimal design of a septum in a waveguide tee junction using PSO(Particle Swarm Optimization) algorithm. The objective function of the optimal design is defined by $S_{11}$-parameter of the waveguide tee junction Design variables are established as position of the septum, that are changed to satisfy the design goal Using the developed design interface and PSO algorithm, the objective function converged to the smallest value, showing the validity of the proposed method. The design interface was developed using Microsoft Excel software, enabling easy control of design parameters for user. Also, various analysis parameters can be set in the Excel interface, including waveguide input mode and frequency. After completion of the design, field solutions at user-specified positrons can be extracted to the output files in complex number form.

• Progress in Superconductivity
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• v.14 no.2
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• pp.77-81
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• 2012

With conventional mass spectrometry (MS), ions are separated according to mass/charge (m/z) ratios. We must speculate the z values to obtain the m values. Superconducting tunnel junction (STJ) detectors can solve this problem, and true mass spectrometry becomes possible instead of m/z spectrometry. The STJ detectors were installed in MS instruments with a variety of ion sources. As an example, we report fragmentation analysis of a non-covalent protein complex of hemoglobin.

• Proceedings of the Microbiological Society of Korea Conference
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• 2004.05a
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• pp.45-46
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• 2004

• Molecules and Cells
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• v.46 no.10
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• pp.589-591
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• 2023