• 한방안이비인후피부과학회지
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• 제16권2호
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• pp.57-77
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• 2003

Objectives: The aim of this study was to investigate the depigmentation effects of Barley, Unpolished rice, Job's-tear. Metbods: We investigated that the extracts of Barley, Unpolished rice, Job's-tear inhibit activity of tyrosinase, the enzyme which convert ts 3-(3,4-dihydroxyphenyl) alanine to dopachrom in the biosynthetic process of melanin, the UV absorbance of the extracts in the UV-A region and UV-B region was measured by UV scanning, the effect of extracts on cell viability and melanin production in cultured B16 mouse melanoma cells were measured, and cytoprotective effects of extracts on PC12 cells injured by hydrogen peroxide measured by MTT assay. Results: The extracts of Barley, Unpolished rice, Job's-tear inhibited activity of tyrosinase in low density. The Barley, Job's-tear extracts not only showed inhibitory effects on melanin production in cultured B16 mouse melanoma cells, but also exhibited cytoprotective effects on PC12 cells injured by hydrogen peroxide in low density. Unpolished rice extract showed inhibitory effect on melanin production in cultured B16 mouse melanoma cells, but did not showed cytoprotective effect Barley, Unpolished rice, Job's-tear extracts did not showed an absorbance effect in the UV-A region and UV-8 region. Conclusions: These results suggest that Barley, Unpolished rice, Job's-tear inhibit melanin biosynthesis which is involved in hyperpigmentation and could be used as a whitening agent.

• 한국식품조리과학회지
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• 제18권2호
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• pp.193-199
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• 2002

죽류의 편의 식품화 및 전통죽의 개발일환으로써 영양적으로 우수한 율무를 이용하여 율무죽을 개발하고자 특성을 조사하였다. 즉, 죽 제조시 쌀가루와 율무가루의 배합비율, 입자크기 및 수침시간에 따른 amylograph 특성을 Brabender visco-amylograph로 측정하였으며, 또한 관능적 특성 및 저장기간동안 율무죽의 품질특성변화를 연구하였다. 쌀가루 및 율무가루의 배합비율에 따른 율무죽의 amylograph 특성을 보면 호화개시온도 및 최고점도는 율무가루의 첨가량이 증가될수록 낮아졌다. 쌀가루 및 율무가루의 입자크기에 따른 amylograph 특성을 보면 호화개시온도는 입자의 크기가 미세할수록 낮았으나 최고점도 및 consistency는 입자의 크기가 미세할수록 높았다. 쌀가루 및 율무가루의 수침시간에 따라서 호화개시온도는 수침시간이 길어짐에 따라 약간 낮아졌으며 5$0^{\circ}C$의 냉각점도 및 consistency도 수침하지 않은 시료가 가장 높았고 수침시간이 길어짐에 따라 낮았다. 쌀가루와 율무가루의 배합비율에 따른 율무죽의 관능검사 결과 율무가루의 첨가량이 많을수록 색의 기호도는 저하되었으나 구수한 맛은 높게 평가되었고 전반적인 기호도는 쌀가루와 율무가루의 배합비율이 50:50인 경우 가장 높게 평가되었다. 율무죽을 제조한 다음 4$^{\circ}C$ 온도에서 14일 저장하는 동안 율무죽의 pH 및 점도 변화는 쌀가루와 율무가루 배합비율, 입자크기 및 수침시간에 따라 저장 초기에서 저장 6일까지 약간 증가하는 현상을 나타내었으나 저장 6일 후에는 감소하는 현상을 나타내었다. 이상의 실험결과로 쌀가루와 율무가루를 이용한 죽의 제조시 고려되어야 할 배합비율, 입자크기, 수침시간에 따른 특성, 관능적 특성 및 저장성을 살펴보았으며 추후 산업화를 위한 기초자료로 이용할수 있을 것으로 생각된다.

• 한국식품영양학회지
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• 제19권2호
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• pp.201-206
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• 2006

Numerous investigators have studied various activities of natural products and have found that they have not only nutritional effects, but also beneficial properties to cure various diseases and to maintain good health. Job's Tear(Yul-Moo) is a grass crop that has long been used in traditional medicine and as a nourishing food. Although its mechanism of action remains unclear, Job's Tear has been reported to exhibit anti-inflammatory, stomachic, anti-allergic, and anti-spastic effects and has been used in China for the treatment of warts, rheumatism, and neuralgia. Previous results in our laboratory demonstrated that the ethanol extract and the water extract of Job's Tear exerted an immune regulatory function on mice cells in vitro. The present study was performed to investigate the ex vivo effect of Job's Tear on immune function. Seven to eight weeks old mice(Balb/c) were fed chow diet ad libitum and water extract of Job's Tear was administered orally every other day for four weeks at two different concentrations(50 and 500mg/kg B.W.). Splenocytes proliferation with mitogen stimulation with Con A and LPS was enhanced at 50 mg/kg B.W. of Job's Tear compared to those of the control group. The results of this ex vivo study showed that proliferation of splenocytes and macrophage activation were seen in the mice orally administrated 50 mg/kg B.W. of Job's Tear water extracts. In conclusion, this study suggests that Job's Tear extracts may enhance immune function by regulating splenocyte proliferation and the cytokine prodution capacity of activated macrophages in mice.

• 한국식품영양학회지
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• 제21권2호
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• pp.204-209
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• 2008

The present study examined the ex vivo effect of Job's tear on immune function. Seven to eight week old mice(Balb/c) were fed a chow diet ad libitum two different concentrations (50 and 500 mg/kg BW) of water extract of Job's tear were orally administ every other day for two weeks. The results indicated that macrophage activation had occurred in the mice receiving 50 mg/kg B. W. of Job's tear water extract. Overall, using a mouse model, this study demonstrated that Job's tear extract may enhance immune function by regulating the $IL-1{\beta}$, IL-6, $TNF-{\alpha}$ and IL-10 cytokine production capacity of activated macrophages in mice. This study may suggest that supplementation of Job's tear water extracts may enhance the immune function by regulating the enhancing the cytokine production by activated macrophage ex vivo.

• 대한영양사협회학술지
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• 제11권1호
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• pp.44-50
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• 2005

Natural products are increasingly appreciated as a lead for drug discovery and development. A number of investigators have studied various activities of natural products and have found that they have not only nutritional effects but also beneficial properties to cure various diseases and to maintain good health. Job's Tear(Yul-Moo) is a grass crop that have long been used in traditional medicine and a nourishing food. Job's Tear has been reported to exhibit anti-inflammatory, stomachic, antiallergic activity, and antispastic effects and has been used in China for the treatment of warts, rheumatism, and neuralgia although its mechanism remains unclear. Previous results in our laboratory demonstrated that the ethanol extract and water extract of Job's Tear exerted an immune regulatory function on mice cells in vitro. The present study was performed to investigate the ex vivo effect of Job's Tear on immune function. Seven to eight weeks old mices(Balb/c) were fed ad libitum on chow diet and water extract of Job's Tear were orally administrated every other day for two or four weeks at two different concentrations (50 and 500mg/kg B.W.). Proliferation of mice spenocytes and antibody production to sheep red blood cells(SRBC) using hemolytic plague forming cell assay were used to indicate the immune activity. Splenocytes proliferation of Job's Tear with mitogen stimulation such as Con A and LPS was enhanced at 50 mg/kg B.W. concentrations compared to those of control group. In case of antibody production to sheep red blood cells, the number of antibody- secreting cells was increased by administration of 50mg/kg B.W. concentration in mice immunized as a T-dependent antigen. From the present study, Job's Tear water extracts may be suggested to stimulate the mice immune response by enhancing the splenocytes proliferation and the number of plague forming cells.

• 한국식품영양과학회지
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• 제29권2호
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• pp.252-256
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• 2000

심장순환기계 질환은 혈중 지질의 상승에서 오며 우리나라의 심장순환계질환은 증가추세로 전체 사망자의 30% 이상을 차지하고 있다. 최근 율무의 혈중 콜레스테롤 농도 저하 작용 가능성이 알려짐으로서 지질대사에도 관여하는 것으로 밝혀졌다. 본 실험에서는 고지방식이로 유발된 고지혈증 흰쥐에서 율무 가공제품인 율무 시리얼의 급여에 의한 혈청 및 간의 지질 성상 개선 효과를 검토하였다. 5주간 고지방 식이군과 율무 시리얼을 5% 대체하여 섭취시킨 결과, 율무제품군이 혈액내 중성지방 함량을 감소시켰으며, 총콜레스테롤, HDL-콜레스테롤 및 LDL-콜레스테롤 함량에는 유의성 있는 변화가 없었다. 동맥경화지수는 율무제품섭취에 의하여 약 20%정도 낮게 나타났다. 간장 중의 콜레스테롤과 중성지방 함량은 대조군과 실험군 간에 유의차가 나타나지 않았다. 이상의 결과에서 율무 가공제품인 율무 시리얼 섭취는 고지방식이를 섭취한 흰쥐의 고지혈증 개선 및 심장혈관계 질환의 예방에 효과의 가능성이 있음이 확인되었다.

• 한국응용과학기술학회지
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• 제7권2호
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• pp.83-90
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• 1990

This study was attempted to observe the effect of Job's tear diet on change of body weight and tissue in rat. The changes of body weight were higher in Job's tear non-diet group(A) and seemed to lower in Job's tear diet group(c) as expected. The weight of each organ appeared to heavy more C group than A,Bgroup in Brain, Spleen. Lungs and Kidney. Liver was heavier in Job's tear to diet one day among six day group(B) and ovary was lighter in C group, The levels of each organ TBA-value were higher in Brain, Liver of A group and showed to higher Spleen, Lungs, Ovary of C group TBA-value of Kidney was revealed to lower more C group than A,B group.

• 한국응용과학기술학회지
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• 제7권2호
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• pp.1-10
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• 1990

This study was attempted to report the effect of Does for Job's tear on steroid hormone changes in rats. Experimental object was one male rat and four female rats in one group. The experimental diet keeped pace with basal diet and Does of Job's tear. A group was basal diet and basal diet & Does for Job's tea was B group(1/day), C group(2/day). D group(3/day), F group(1 day among 3 day, 3/day), G group (1day among 5 day. 3/day) and E group was made diet & Job's tear(3/day). The reduce of weight was appeared to higher in D group and revealed to higher was F, C, B, G and A group. The changes of steroid hormone were showed to significant difference in A group and indicated to significant difference were G, F, B, C, D and E group.

• 한국식품과학회지
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• 제45권4호
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• pp.473-477
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• 2013

혼합디자인에 의해 설정된 조건하에서 압출성형한 율무와 밀가루의 압출성형물은 율무 첨가에 대해 여러 반응 요인들이 압출성형물의 특성에 영향을 끼치는 것으로 나타났다. 실험조건은 율무 함량 5-75%, 밀가루 25-95%로 결정하였으며, 수분함량은 20.55%로 고정하여 modified distance based mixture design으로 실험설계 및 분석하였다. Bending 파손강도, WAI, a값 등은 유의성이 없는 것으로 나타났으나, 팽화물의 직경, WSI, L값, b값은 율무와 밀가루의 혼합에 의해 유의성이 존재하는 것으로 나타났다. 팽화물의 직경, L값, b값은 선형 모델로 분석할 수 있었으나 WSI는 quadratic 모델로만 설정이 가능한 것으로 나타났다. 율무의 함량이 많아질수록 외관적으로 팽창되어지는 정도가 적어졌으며, 색상도 어두워지는 것으로 나타났다. 율무의 함량이 증가할수록 L값은 77.84에서 72.73, a값은 1.37에서 1.77로, b값은 19.42에서 17.64로 이동되었다. WSI는 율무와 밀가루가 40%:60%로 혼합되어 압출성형되었을 때 가장 낮게 나타났으며, WAI는 율무와 밀가루 혼합 비율에 대해서는 유의성이 없는 것으로 나타났다. 혼합디자인 계획법은 시리얼류 제품 생산에 적합한 조직 형성과 반응량에 유의한 영향을 미치는 요인 등에 대해 적절한 혼합 비율과 가공 조건 등을 제시할 수 있음을 알 수 있었다. Modified distance based mixture design에 의해, 일반 시중 제품과 유사한 조직감을 나타낼 수 있는 율무와 밀가루, 물의 적정 배합 비율은 60.12:19.42:20.46으로 나타났다.

• 한국식품조리과학회지
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• 제23권5호
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• pp.770-776
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• 2007

The aim of this study was to determine the optimum addition amount of Job's tears flour, in place of rice flour, in the preparation of Yulmoo Jeolpyon (Job's tears rice cake). The moisture contents of the Jeolpyon samples with added Job's tears flour were 43-45%. With increasing additions of Job's tears flour, the L-value decreased, whereas the a- and b-values increased. In the mechanical evaluation of the Job's tears Jeolpyon, hardness decreased with increasing amounts of Job's tears flour. Cohesiveness, springiness, gumminess and chewiness were lower in the Jeolpyon samples with added Job's tears flour with more than 0% Job's tears flour, respectively. The adhesiveness did not differ significantly with the addition of Job's tears flour. In the sensory evaluation, overall acceptability was highest at the 20% level of Job's tear flour. In conclusion the Jeolpyon made with 20% Job's tear flour to rice flour was found to be the best formulation, in terms of its overall acceptability and textural qualities.