• Title/Summary/Keyword: Intuitive

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Pathogen Associated Molecular Pattern (PAMP)-Triggered Immunity Is Compromised under C-Limited Growth

  • Park, Hyeong Cheol;Lee, Shinyoung;Park, Bokyung;Choi, Wonkyun;Kim, Chanmin;Lee, Sanghun;Chung, Woo Sik;Lee, Sang Yeol;Sabir, Jamal;Bressan, Ray A.;Bohnert, Hans J.;Mengiste, Tesfaye;Yun, Dae-Jin
    • Molecules and Cells
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    • v.38 no.1
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    • pp.40-50
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    • 2015
  • In the interaction between plants and pathogens, carbon (C) resources provide energy and C skeletons to maintain, among many functions, the plant immune system. However, variations in C availability on pathogen associated molecular pattern (PAMP) triggered immunity (PTI) have not been systematically examined. Here, three types of starch mutants with enhanced susceptibility to Pseudomonas syringae pv. tomato DC3000 hrcC were examined for PTI. In a dark period-dependent manner, the mutants showed compromised induction of a PTI marker, and callose accumulation in response to the bacterial PAMP flagellin, flg22. In combination with weakened PTI responses in wild type by inhibition of the TCA cycle, the experiments determined the necessity of C-derived energy in establishing PTI. Global gene expression analyses identified flg22 responsive genes displaying C supply-dependent patterns. Nutrient recycling-related genes were regulated similarly by C-limitation and flg22, indicating re-arrangements of expression programs to redirect resources that establish or strengthen PTI. Ethylene and NAC transcription factors appear to play roles in these processes. Under C-limitation, PTI appears compromised based on suppression of genes required for continued biosynthetic capacity and defenses through flg22. Our results provide a foundation for the intuitive perception of the interplay between plant nutrition status and pathogen defense.

Scalable RDFS Reasoning Using the Graph Structure of In-Memory based Parallel Computing (인메모리 기반 병렬 컴퓨팅 그래프 구조를 이용한 대용량 RDFS 추론)

  • Jeon, MyungJoong;So, ChiSeoung;Jagvaral, Batselem;Kim, KangPil;Kim, Jin;Hong, JinYoung;Park, YoungTack
    • Journal of KIISE
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    • v.42 no.8
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    • pp.998-1009
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    • 2015
  • In recent years, there has been a growing interest in RDFS Inference to build a rich knowledge base. However, it is difficult to improve the inference performance with large data by using a single machine. Therefore, researchers are investigating the development of a RDFS inference engine for a distributed computing environment. However, the existing inference engines cannot process data in real-time, are difficult to implement, and are vulnerable to repetitive tasks. In order to overcome these problems, we propose a method to construct an in-memory distributed inference engine that uses a parallel graph structure. In general, the ontology based on a triple structure possesses a graph structure. Thus, it is intuitive to design a graph structure-based inference engine. Moreover, the RDFS inference rule can be implemented by utilizing the operator of the graph structure, and we can thus design the inference engine according to the graph structure, and not the structure of the data table. In this study, we evaluate the proposed inference engine by using the LUBM1000 and LUBM3000 data to test the speed of the inference. The results of our experiment indicate that the proposed in-memory distributed inference engine achieved a performance of about 10 times faster than an in-storage inference engine.

An Analysis on Evacuation Scenario at Metro-stations using Pedestrian Movement-based Simulation Model (보행류 기반 도시철도역사 평가 시뮬레이터를 활용한 대피 시나리오 분석)

  • You, So-young;Jung, Rea-hyuck;Chung, Jin-hyuck
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.15 no.2
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    • pp.36-49
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    • 2016
  • A subway system is one of the major transportation modes at a metropolitan area. When it meets the other lines, the metro station, so-called transferring station, is usually threatened by severe pedestrian congestion and safety issue of transit users including the transportation vulnerable. Although transportation planners forecast travel demand at the beginning, it is not easy to predict pedestrian flows precisely for a long term if land use plans have dramatically changed. Due to expensive costs, structural extension of metro stations is limited. Therefore, it requires efficient and technical improvements as meeting the demand of pedestrian and physical characteristics. In this study, the core mechanism of pedestrian movement-based simulation model was introduced and evacuation scenarios were analyzed with the developed model. As a result, the multiple optimal routes for unexpected events at the solid space of the multiple stories are easily searched through the simulator and in the case of Sadang Station, travel time can be reduced by 60% when the evacuation information and intuitive design are provided.

Bayesian Confirmation Theory and Hempel's Intuitions (베이즈주의와 헴펠: 베이즈주의자들은 헴펠의 직관을 포착하는가?)

  • Lee, Ilkwon
    • Korean Journal of Logic
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    • v.22 no.3
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    • pp.351-395
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    • 2019
  • Hempel's original intuitions about the raven's paradox are summed up in three ways. The first is known as the paradoxical conclusion: If one observes that an object a - about which nothing is antecedently known - is a non-black non-raven, then this observation confirms that all ravens are black. The second is an intuitive verdict of the misled conclusion of the paradox: If one observes that an object a - which is known to be a non-raven - is non-black (hence, is a non-black non-raven), then this observation does not confirmationally affect that all ravens are black. The third is a comparative claim between the two intuitions: the degree of confirmation appearing in the first intuition is greater than the degree of confirmation in the second intuition. The Standard Bayesian Solution of the paradox is evaluated to fleshed Hempel's intuitions out by establishing the first intuition. However, such an evaluation of this solution should be further analyzed because Hempel's intuition is not the only one. The solution of paradox does not establish the second intuition in a strict sense. However, I think the Bayesian solution will establish the second intuition based on its typical strategy of quantitative vindication. If only quantitative vindication is accepted, this evaluation of the solution remains valid. Nevertheless, the solution fails to establish the third intuition. In this article, I propose a new way to apply the Bayesian method to establish Hempel's intuitions, including the third intuition. If my analysis is correct, the Standard Bayesian Solution of the raven's paradox could indeed flesh Hempel's intuitions out by denying one of the assumptions considered essential.

A Bio-Edutainment System to Virus-Vaccine Discovery based on Collaborative Molecular in Real-Time with VR

  • Park, Sung-Jun
    • Journal of the Korea Society of Computer and Information
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    • v.25 no.6
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    • pp.109-117
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    • 2020
  • An edutainment system aims to help learners to recognize problems effectively, grasp and classify important information needed to solve the problems and convey the contents of what they have learned. Edutainment contents can be usefully applied to education and training in the both scientific and industrial areas. Our present work proposes an edutainment system that can be applied to a drug discovery process including virtual screening by using intuitive multi-modal interfaces. In this system, a stereoscopic monitor is used to make three-dimensional (3D) macro-molecular images, with supporting multi-modal interfaces to manipulate 3D models of molecular structures effectively. In this paper, our system can easily solve a docking simulation function, which is one of important virtual drug screening methods, by applying gaming factors. The level-up concept is implemented to realize a bio-game approach, in which the gaming factor depends on number of objects and users. The quality of the proposed system is evaluated with performance comparison in terms of a finishing time of a drug docking process to screen new inhibitors against target proteins of human immunodeficiency virus (HIV) in an e-drug discovery process.

A Study on the Development of Mobile APP Usability Evaluation Tool for Time Management (시간관리 모바일 앱 사용성 평가도구 개발에 관한 연구)

  • Lee, Saem;Nam, Won-Suk
    • Journal of the Korea Convergence Society
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    • v.12 no.12
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    • pp.19-29
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    • 2021
  • Although several industrial revolutions and technological developments have provided time for modern people, more than 75% of modern people are currently suffering from the problem of "lack of time". Therefore, in this paper, it was judged that it was necessary to improve the mobile APP service for efficient time management of modern people, and a study was conducted on the development of usability evaluation tools. First, the current status was analyzed through case studies of six time management apps with different purposes, and then usability studies were conducted to establish a total of five evaluation principles with operability, cognition, user suitability, minimization of work errors, and sharing. Based on this, a draft of the time management mobile app usability evaluation item was prepared, and a total of 44 usability evaluation tool items were derived through three Delphi surveys of design experts over 5 years and less than 10 years. As a result, intuitive screen and menu composition and user's perception of content were evaluated as the most important factors, and conclusions such as the need to improve the structure and function of the main content screen for user error prevention and usability were drawn. This study will not only contribute to improving the usability of existing time management mobile apps, but will also be used as a material for designing an integrated time management platform for efficient time management and purpose promotion in the future, and is expected to be used as an academic reference.

A Study on Jin Tai Quan Zhuan (金臺全傳): A Narration in the Form of a Xylographic Book (한국 소장 『김대전전(金臺全傳)』의 판본과 서사 연구)

  • Kim, Myung-Sin
    • Cross-Cultural Studies
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    • v.41
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    • pp.85-112
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    • 2015
  • This article studies The Complete Story of JinTai(金臺全傳), a Korean and Chinese xylographic book, and wishes to makes a case for the value of this work. The Complete Story of JinTai, is an anonymous Xia-Yi (俠義) novel from the late Qing Dynasty. The oldest edition is at Nanjing Rare Book Library. This work was published in 1881 when Emperor Guangxu (光緖) ruled China. Currently, a copy of this book is at the Kookmin University Rare Book Library, however, it is somewhat different in form from that in the Nanjing Library. But it is almost the same story. The Complete Story of JinTai narratives the life story of the hero, Jintai (金臺). Jintai's appearance, alliance, ordeal, contribution, and return proceed sequentially, thus, the story gradually explicates Jintai's heroic aspects. Jintai is a young hero. Exceptionally, he married an official dancing girl. He values honor, hangs out with friends, slays a wicked villain, to the defense of the country, and eventually becomes a king. The hero of more than 500 is categorized as conductor, strategist, activist, intuitive type. They are from Geumsan Mountain, took a pledge of brotherhood, and try to resolve a national crisis. The remarkable Jintai fights wicked enemies and does battle with the villains in many conflicts.

Constructivist interpretation on the modal logic (양상 논리에 대한 구성주의적 해석)

  • Eun, Eun-suk
    • Journal of Korean Philosophical Society
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    • v.116
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    • pp.257-280
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    • 2010
  • I try to formalize the system of modal logic and interpret it in view of constructivism through this study. As to the meaning of a sentence, as we saw, Frege endorsed extensions in view of the fact that they are enough to provide for a compositional account for truth, in particular that (1) the assignment of extensions to expressions is compositional ; (2) the assignment of extensions to sentences coincides with the assignment of truth values. But nobody would be willing to admit that a truth value is what a sentence means and that consequently all true sentences are synonymous. So, if what we are after is meaning in the intuitive sense, then extensions would not do. This consideration has later become the point of departure of modal and intensional semantics. So, it is clear that the language of modal logic do not allow for an extensional interpretation. ${\square}$ is syntactically on a par with ${\vdash}$, hence within the extensional framework it would have to denote a unary truth function. This means that if modal logic is to be interpreted, we need a semantics which is not extensional. The first attempt to build a feasible intensional semantics was presented by Saul Kripke. He came to the conclusion that we must let sentences denote not truth values, but rather subsets of a given set. He called elements of the underlying set possible world. Hence each sentence is taken to denote the set of those possible world in which it is true. This lets us explicate necessity as 'truth in every possible world' and possibility as 'truth in at least one possible world'. But it is clear that the system of modal logic is not only an enlargement of propositional logic, as long as the former contains the new symbols, but that it is of an other nature. In fact, the modal logic is intensional, in that the operators do not determine the functions of truth any more. But this new element is not given a priori, but a posteriori from construction by logicist.

A study on user experience of Instagram IGTV -Focus on fashion·beauty contents service (인스타그램 IGTV의 사용자 경험 연구 -패션·뷰티 콘텐츠 서비스를 중심으로-)

  • Woo, Soo-Hee;Kim, Seung-In
    • Journal of Digital Convergence
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    • v.17 no.3
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    • pp.405-411
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    • 2019
  • The purpose of the study is to investigate a usability of using fashion and beauty service and suggest better user experience on Instagram's newly released mobile video platform, IGTV. The study expects to be a resource of improving the usability on fashion and beauty contents on IGTV and encourage further research for suggesting better guidelines. As a research method, it will experiment current mobile video service first with literature review. Afterwards, the research conducted tasks and in-depth interview with eight Instagram users to evaluate a usability of using fashion and beauty service on IGTV. As a result, it is able to derive two plans that needed improvement. Firstly, IGTV is required to have high accessibility for user's to use service longer and intuitive user experience. Secondly, unlike previous service that Instagram have offered, IGTV need to differentiate to share and get information of fashion and beauty trends.

The Relationship among the Parent-Adolescent Communication Styles, Self-Esteem, Depression and Career Decision-Making Styles Perceived by Middle School and High School Students (중고등학생이 지각한 부모-자녀 간의 의사소통유형, 자아존중감, 우울과 진로의사결정유형의 관계)

  • Seo, Yong Won;Lee, Jee Sook;Kim, Hyun Soon;Lim, Myung Ho
    • The Journal of the Korea Contents Association
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    • v.18 no.12
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    • pp.173-184
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    • 2018
  • The purpose of this study was to investigate the relationship among the parent-adolescent communication styles, self-esteem, depression and career decision-making styles. The subjects were 399 middle school students and 366 high school students in four middle schools and two high schools in metropolitan and small towns for one month from July 1, 2017. Data were analyzed through descriptive statistics, correlation analysis. Multiple regression was used to see how parent-adolescent communication styles, self esteem, and depression affect the career decision-making style. As a result, first, open communication with mothers has a statistically significant effect on the rational career decision-making style and open communication with fathers has a statistically significant effect on the intuitive career decision-making style of adolescents. Second, self-esteem of adolescents showed a positive correlation with rational career decision-making style and negative correlation with dependent career decision-making style, and depression showed a positive correlation with dependent career decision-making style. The results may help to understand the relationship among the parent-adolescent communication styles, self-esteem, depression and career decision-making styles and be used for counseling intervention.