• Journal of the Korean Home Economics Association
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• v.44 no.3 s.217
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• pp.115-126
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• 2006

The purpose of this study was to propose theoretical-practical strategies of family-based intervention for the "Healthy Family-Support Center." The theoretical background used was an ecological approach, that is, taking viewpoints of client family's microsystems as well as those of exo- and macrosystems. This study raised several critical points in researching and developing family-based intervention programs. Based on a review of the literature, the study indicated why an ecological, family-based intervention model was a relevant alternative to investigate issues in family welfare and to deliver possible assistance and solutions for them.

• The Journal of Korean Physical Therapy
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• v.22 no.2
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• pp.39-46
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• 2010

Purpose: This study was designed to determine whether General Coordinative Manipulation (GCM) Intervention Models have effects on the balanced restoration of asymmetrical muscles in the extremities. Methods: Fifty-nine healthy subjects (1st hypothesis: n=40, 2nd hypothesis: n=19) participated in studies using the two GCM intervention models. Subjects were studied 2 times a week for 3 weeks. Electromyography (EMG) was used to measure muscle activity, and measurements were performed before and after the application of the each intervention model. Results: Hypothesis 1: GCM Intervention, which coordinates flexion types of muscle contractions of the upper extremity and extension types of muscle contractions of the lower extremity (excluding self-care) is effective for treating shows the treatment in efficiency on more than two 2 of 3 muscles (vastus medialis, gastrocnemius medial, and deltoid middle) and the effects affects on more than 3 types of 4 body types (Vastus medialis, Gastrocnemius medial of Body type III, p<0.05). GCM body type was classified by the relative tilting of right and left scapulars and iliums into four groups. Hypothesis 2: GCM Intervention, which coordinates flexion types of muscle contractions of the lower extremity and extension types of muscle contractions of the upper extremity (excluding self-care) is effective for treating more than two 2 of 3 muscles (vastus medialis, gastrocnemius medial, and deltoid middle) and the effects affects on more than 2 types of 3 body types (p>0.05).

• Journal of the Korean Society for Industrial and Applied Mathematics
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• v.21 no.3
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• pp.143-154
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• 2017

This paper presents the mathematical model for the MERS-CoV outbreak in South Korea, and the optimal control for two intervention strategies (contact, hospitalization) is implemented. After the MERS-CoV outbreak, hospitalizing infected individuals did not help to prevent the spread of infection. However, the intervention to control contact was effective. It was effective the intervention to controlling both of contact and hospitalization of infection population.

• Therapeutic Science for Rehabilitation
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• v.2 no.1
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• pp.87-91
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• 2013

Objective : This case study examined the evaluation of occupational therapy and plan to intervention of community asperger syndrome child receiving coping model. Methods : We selected child which 7-year-old boy. Evaluation periods were 2weeks which consisted of external factors and internal factors. External factors were made up interaction of subject, environments and participation of school and community. Internal factors were made up observation and structured evaluation about development state and medical conditions. Also it included observation of appropriate mood and emotions. Results : After evaluation receiving coping model, we planed to intervention. First, subject able to use his time effectively. Second, we'll have intervention program about delayed fine motor areas. Third, we'll educate self-control skills and coping skills of subject's action which not controlled himself. Fourth, we'll find the personal and physical sources to care subject. Conclusion : Our research has planed occupational therapy intervention receiving coping model of asperger syndrome subject. Future research need to practical applications.

• The Journal of Korean Academy of Sensory Integration
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• v.15 no.2
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• pp.22-34
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• 2017

Objective : The purpose of this study was to draw up sensory integration intervention competency model for occupational therapist and was to confirm a competency model through validation. Methods : We conducted literature review, expert opening survey, and expert focus meeting to draw up draft competency model. And then, we carried out Delphi survey twice and consulted an expert to confirm the sensory integration intervention competency model for occupational therapist. Results : The sensory integration intervention competency model for occupational therapist developed in this study was structured into 4 competency cluster, 15 competency, 60 competency indicators. 4 competency clusters had expertise, professionalism, interpersonal skills, and personal characteristics. Conclusion : The competency model revealed in this study can be used as basic critical data to foster development of competency based curriculum of Korean Academy of Sensory Integration (KASI).

• Biomolecules & Therapeutics
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• v.26 no.6
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• pp.539-545
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• 2018

4-Hydroxy-2-(4-hydroxyphenethyl)isoindoline-1,3-dione (PD1) is a synthetic phthalimide derivative of a marine compound. PD1 has peroxisome proliferator-activated receptor (PPAR) ${\gamma}$ agonistic and anti-inflammatory effects. This study aimed to investigate the effect of PD1 on allergic asthma using rat basophilic leukemia (RBL)-2H3 mast cells and an ovalbumin (OVA)-induced asthma mouse model. In vitro, PD1 suppressed ${\beta}$-hexosaminidase activity in RBL-2H3 cells. In the OVA-induced allergic asthma mouse model, increased inflammatory cells and elevated Th2 and Th1 cytokine levels were observed in bronchoalveolar lavage fluid (BALF) and lung tissue. PD1 administration decreased the numbers of inflammatory cells, especially eosinophils, and reduced the mRNA and protein levels of the Th2 cytokines including interleukin (IL)-4 and IL-13, in BALF and lung tissue. The severity of inflammation and mucin secretion in the lungs of PD1-treated mice was also less. These findings indicate that PD1 could be a potential compound for anti-allergic therapy.

• Journal of Ginseng Research
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• v.42 no.1
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• pp.68-74
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• 2018

Background: Ginsenosides have been reported to have many health benefits, including anti-inflammatory effects, and the resolution of inflammation is now considered to be an active process driven by M2-type macrophages. In order to determine whether ginsenosides modulate macrophage phenotypes to reduce inflammation, 11 ginsenosides were studied with respect to macrophage polarization and the resolution of inflammation. Methods: Mouse peritoneal macrophages were polarized into M1 or M2 phenotypes. Reverse transcription-polymerase chain reaction, Western blotting, and measurement of nitric oxide (NO) and prostaglandin $E_2$ levels were performed in vitro and in a zymosan-induced peritonitis C57BL/6 mouse model. Results: Ginsenoside $Rg_3$ was identified as a proresolving ginseng compound based on the induction of M2 macrophage polarization. Ginsenoside $Rg_3$ not only induced the expression of arginase-1 (a representative M2 marker gene), but also suppressed M1 marker genes, such as inducible NO synthase, and NO levels. The proresolving activity of ginsenoside $Rg_3$ was also observed in vivo in a zymosan-induced peritonitis model. Ginsenoside $Rg_3$ accelerated the resolution process when administered at peak inflammatory response into the peritoneal cavity. Conclusion: These results suggest that ginsenoside $Rg_3$ induces the M2 polarization of macrophages and accelerates the resolution of inflammation. This finding opens a new avenue in ginseng pharmacology.

• Journal of Korean Biological Nursing Science
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• v.22 no.1
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• pp.1-10
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• 2020

Purpose: Diabetes Mellitus (DM) is a leading cause of death with a prevalence rate of 12.4% in South Korea. Self-management is crucial for patients with DM, because many studies have reported that self-management intervention based on the Health Belief Model (HBM) is effective. The purpose of this study was to investigate the current state of HBM based intervention studies and the components and effects of the theories used in the study for diabetes patients. Methods: A systematic review was conducted using the Pubmed, Cochrane Library and Embase databases from January 2009 to May 2019. We reviewed characteristics of intervention based on the HBM in randomized controlled clinical trials (RCTs), quasi-experimental study intervention. Results: Eight studies published in English between 2009 and 2019 were included in this review. The key components of the health behavior promotion program applied to the DM patients were perceived susceptibility, perceived severity, perceived benefits, perceived barriers and self-efficacy. The intervention based on these components has reported to significantly increase the health behavior change, likelihood of taking health action and improve physiological indicators (HbA1c, and fasting blood sugar etc.). Conclusion: This study highlighted the importance of intervention programs based on the HBM for DM patients.

• Research in Community and Public Health Nursing
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• v.32 no.1
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• pp.51-63
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• 2021

Purpose: This study aimed to develop an integrated health promotion program for cancer survivors residing in the community based on the shared care model, and evaluate its effectiveness. Methods: A quasi-experimental trial was conducted. The participants consisted of 35 cancer survivors with completed intensive cancer therapy at the cancer hospital. The intervention group (n=20) and the control group (n=15) were recruited from among a district home cancer patient registrations. The intervention group participated in an integrated health promotion program based on the MAPP (Mobilizing for Action through Planning and Partnership) development process. The program consisted of physical, psycho-social and body image units. The participants were assessed before the program, and immediately after the program. Data were collected between July 1 and September 2, 2018 using FACT-G quality of life (QOL), distress thermometer (DT), and resilience. The data were analyzed by performing a χ2 test, Fisher's exact test, Mann-Whitney test, and ranked ANCOVA using SPSS. Results: The intervention group reported a higher QOL overall and significantly higher social/family well-being than the control group. Distress was significantly lower in intervention group than in the control group. Resilience had no significant difference between the two groups. Conclusion: These findings indicate that the integrated health promotion program base on the shared care model and MAPP development process could be effective intervention for improving social/family well-being and the QOL, and reducing distress of cancer survivors at home. Community health center nurses need to provide intervention to support self-care competency for cancer survivors' comprehensive care with physical, psycho-social, and body image to help them adjust their life to a moderate risk group in the community.

• The Korean Journal of Applied Statistics
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• v.27 no.3
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• pp.419-430
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• 2014

An accurate prediction of electricity supply and demand is important for daily life, industrial activities, and national management. In this paper electricity sales is predicted by time series modelling. Real data analysis shows the transfer function model with cooling and heating days as an input time series and a pulse function as an intervention variable outperforms other time series models for the root mean square error and the mean absolute percentage error.