• 제3의학
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• 제1권1호
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• pp.57-89
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• 1996

A Typification of diagnosis and treatment(DT) model must be done in order to generalize the objective stage to the result of treatment to internal disease in connection with the type of viscera and bowel symptom. We could find 108 DT models in internal disease from the combination of 18 types of viscera and bowel and 6 types of DT treatment processes. Thus, the typification of 108 models of DT can be viewed as a modeling processes of utilizing DT knowledge at each stage. We argue that objectivity in diagnosis and treatment of internal disease can be obtained practically from typification of DT model.

• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2010년도 제35회 추계학술대회논문집
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• pp.213-216
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• 2010

본 연구에서는 고체 추진기관의 침식연소 해석을 위한 비정상 일차원 내탄도 해석 모델을 개발하였다. 연소실 축방향 유동과 압력변화를 해석하기 위해 연속방정식과 운동량 보존식을 연립하여 수치해석 하였다. 기존에 검증된 고체 추진기관 무차원 내탄도 해석 프로그램과 해석 결과를 비교하여 개발한 해석 모델을 검증하였다. 그레인 직경 대 길이비가 큰 모터의 축방향 연소속도, 압력, 속도 변화를 고찰하였다.

• EDISON SW 활용 경진대회 논문집
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• 제5회(2016년)
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• pp.222-227
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• 2016

In this paper, the optimized design for bow structure was investigated by using EDISON software. Considering the mechanism of the bow, non-linear FEM analysis was essential. The factors of the design are height, width, number of holes and taper value. High performance of the internal energy and lowest mass were main issues. The limit of the von-mises stress was yield strength for the material. Material was chosen by considering typical bow material, Aluminum. Using Taguchi method($L_9$), 9 models were selected and contribution rate was calculated for each factors. Following the contribution rate, 3 factors were fixed and optimized model was predicted. After making optimized model for FEM analysis, the value of internal-energy, mass for FEM model were compared with predicted value, calculated the percentage error and figure out the reliability of Taguchi method.

• 대한의용생체공학회:의공학회지
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• 제25권4호
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• pp.283-288
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• 2004

본 논문에서는 작은 여성 승객의 충돌해석을 위한 유한요소 모델링에 대하여 Part I 의 분절된 강체 모델에 이어 소개하고 있다. 추가로 모델링 된 상세한 팔, 다리 및 내부 요소들이 분절된 강체 모델에 합체되어 충돌 상해 즉 골절 또는 탈골 등을 예측하게 된다. 이러한 사지 및 내부 요소들의 거동 특성은 확보된 사체 실험 결과와 비교, 검증하였다. 따라서 본 논문에서 제안하고 있는 작은 여성 인체 모델은 충돌 상해 기구학의 조사 및 현존하는 충돌 더미의 생체 충실도를 보완하는데 활용될 수 있다.

• 한국정밀공학회지
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• 제25권3호
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• pp.157-164
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• 2008

While developing physical prototype from CAD model, rapid prototyping mainly focuses on two key points reducing time and material consumption. So, we have to change from a traditional solid model to building a hollowed prototype. In this paper, a new method is presented to hollow out solid objects with uniform wall thickness to increase RP efficiency. To achieve uniform wall thickness, it is necessary to generate internal contour by slicing the offset model of an STL model. Due to many difficulties in this method, this paper proposes a new algorithm that computes internal contours computing offset model which is generated from external contour using wall thickness. Proposed method can easily compute the internal contour by slicing the offset surface defined by the sum of circle swept volumes of external contours without actual offset and the circle wept volumes. Internal contour existences are confirmed by using the external point. Presented algorithm uses the 2D geometric algorithm allowing RP implementation more efficient. Various examples have been tested with implementation of the algorithm, and some examples are presented for illustration.

• 한국수소및신에너지학회논문집
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• 제24권5호
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• pp.401-412
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• 2013

The paper is to study on the simulation of the micro/macroscale thermo-electrochemical model of a single cell of anode-supported SOFC with direct internal reforming. The coupled heat and mass transport, electrochemical and reforming reactions, and fluid flow were simultaneously simulated based on mass, energy, charge conservation. The micro/macroscale model first calculates the detailed electrochemical and direct internal reforming processes in porous electrodes based on the comprehensive microscale model and then solve the macroscale processes such as heat and mass transport, and fluid flow in SOFCs with assumption of fully-developed flow in gas channel. The simulation results evaluate the overall performance by analyzing distributions of mole fraction, current density, temperature and microstructural design in co/counter flow configurations.

• 대한한의학회지
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• 제34권1호
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• pp.1-14
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• 2013

Objectives: This study was designed to investigate the anti-obesity, anti-diabetic and anti-inflammatory effects of Platycodi radix on obese type 2 diabetes mouse model. Methods: Obese type 2 diabetes mouse model was induced by Surwit's high fat, high sucrose diet for 8 weeks. Models were divided into 4 groups of normal diet (ND, n=10), high fat and high sucrose diet (HFD, n=10), high fat and high sucrose diet with Platycodi radix (PR, n=10), and high fat and high sucrose diet with Metformin (Met, n=10). Body weights were measured every week. After 7 weeks fasting, blood sugar and oral glucose tolerance tests were conducted. After 8 weeks blood samples were taken from mouse hearts and analyzed biochemically. Lipid profile, fructosamine, leptin and weight of epididymal fat pad and liver were measured. Adipose tissue macrophage percentage was analyzed by fluorescence-activated cell sorting (FACS). Results: Compared with the HFD group, body weight, glucose level, fructosamine, weight of epididymal fat pad and adipose tissue macrophage percentage decreased in the PR group. Conclusions: These results suggest that Platycodi Radix has anti-obesity, anti-diabetic, and anti-inflammatory effects on obese type 2 diabetes mouse model.

• Ocean and Polar Research
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• 제36권1호
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• pp.1-12
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• 2014

This study investigates spatial and temporal variations in the generation and propagation of internal tides around the Korea Strait using a three-dimensional high resolution model (Regional Ocean Modeling System; ROMS). The model results were verified through comparison with in-situ current measurements from an array of 12 acoustic Doppler current profilers (ADCPs) deployed in the Korea Strait. Fluxes and distributions of internal tidal energy were calculated using simulation results gathered in February and August. Our analyses reveal that energetic semidiurnal internal tides are generated in a region around the Korea Strait shelf break ($35.5^{\circ}N$, $130^{\circ}{\sim}130.5^{\circ}E$), where the strong cross-slope semidiurnal barotropic tidal currents interact with a sudden topographical change. The semidiurnal internal tidal energy generated in summer displays values about twice as large as values in winter. Propagation of semidiurnal internal tides also reveals seasonal variability. In February, most of the semidiurnal internal tides propagate only into the open basin of the East Sea due to weak stratification in the Korea Strait, which inhibits their southwestward propagation. In August, they propagate southwestward to $35.2^{\circ}N$ along the western channel of the Korea Strait because of strong stratification. In addition, semidiurnal internal tides generated in a region west of Tsushima Island are found to propagate to the coast of Busan. This can be explained by the intensified stratification due to the strong intrusion of bottom cold water in the western channel of the Korea Strait during summer.

• Asian Pacific Journal of Cancer Prevention
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• 제13권3호
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• pp.1059-1063
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• 2012

Objective: Angiogenesis represents a key element in the pathogenesis of malignancy. There are no robust data on prognostic factors for overall survival (OS) in patients with metastatic colorectal cancer treated with vascular endothelial growth factor (VEGF)-targeted therapy. The present study was conducted to establish a prognostic model for patients using an oxaliplatin-based or irinotecan-based chemotherapy plus bevacizumab in metastatic colorectal cancer. Methods: Baseline characteristics and outcomes on 170 patients treated with FOLFIRI or XELOX plus anti-VEGF therapy-naive metastatic colorectal cancer were collected from three Turkey cancer centers. Cox proportional hazards regression was used to identify independent prognostic factors for OS. Results: The median OS for the whole cohort was 19 months (95% CI, 14.3 to 23.6 months). Three of the seven adverse prognostic factors according to the Anatolian Society of Medical Oncology (ASMO) were independent predictors of short survival: serum lactate dehydrogenase (LDH) greater than the upper limit of normal (ULN; p<0.001); neutrophils greater than the ULN (p<0.0014); and progression free survival (PFS) less than 6 months (p =0.001). Conclusion: Serum LDH and neutrophil levels were the main prognostic factors in predicting survival, followed by PFS. This model validates incorporation of components of the ASMO model into patient care and clinical trials that use VEGF-targeting agents.

• 한국방재학회 논문집
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• 제10권4호
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• pp.105-117
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• 2010

도시지역의 지형적인 저지대, 배수능력 부족, 하수역류 노면배수 등은 내수침수의 주요원인이며 최근 기후변화에 따른 강우증가, 경제발전과 인구증가에 따른 급격한 도시화, 도시지역 불투수 면적의 증가는 도시지역 내수침수의 위험성을 가중시키고 있다. 이에 본 연구는 도시지역의 내수침수 위험도 분석을 위하여 부산시 대표 도시하천인 온천천을 대상유역으로 하여 SWMM 모형을 구축하고 각 소유역의 대표 우수관을 선정하여 강우에 의한 도시하천 내수침수 위험 취약성 분석을 실시하였다. 침수위험 취약성 분석을 위하여 SWMM모형 내 관거의 용량을 나타내는 지표인 Capacity를 이용하였으며 Capacity에 따라 내수침수 위험도를 1단계에서 4단계로 구분하였다. 내수침수 위험도 분석은 2009년 7월 7일 부산시 집중호우에 의한 실제침수 구역과 SWMM 모형의 모의에 의한 결과를 비교 분석하여 모형의 타당성을 입증하고 부산지점 빈도별(10, 20, 50, 100년) 지속시간별(6, 12, 18, 24hr) 확률강우량을 입력하여 내수침수 위험 취약성 분석을 실시하였다. 본 연구의 결과는 도시지역의 내수침수 예경보 및 내수침수 취약지구 선정에 활용가능할 것이다.