• Journal of Korean Society of Water and Wastewater
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• v.27 no.6
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• pp.827-836
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• 2013

Due to the stringent drinking water quality, formaldehyde will be included in Korean drinking water standard from year 2014. However, its standard analytical method has not yet been established. This study compares two analytical methods, DNPH-LC and ACFAS with respect to their analysis principles, Method Detection Limit (MDL), Limit Of Quantitation(LOQ), precision, accuracy, reproducibility, convenience, number of samples analyzed per hour and analysis cost. These methods measure absorption intensity at 360 nm by using HPLC after DNPH-derivatization (DNPH-LC) and at 410 nm by using Automated Continuous Flow Absorption Spectrophotometer (ACFAS), respectively. Reproducibility was tested by repeating the analysis 7 times using a standard solution for each method. For DNPH-LC method, MDL was $0.5{\mu}g/L$, LOQ was $1.58{\mu}g/L$ with standard deviation of $0.16{\mu}g/L$. For ACFAS method, they were $0.27{\mu}g/L$, $0.85{\mu}g/L$L with standard deviation of $0.09{\mu}g/L$, respectively. Both methods satisfied the requirement set by the Korean drinking water quality standard. Complexity of sample pretreatment procedure for DNPH-LC method may cause large error and, consequently, the analytical result will depend on the level of skill of analyst. In contrast, ACFAS method which used only one reagent equipped with an automated injection device showed little analytical error. It costs about $5.00 and $1.00 for one sample to analyze by the DNPH-LC method and the ACFAS method, respectively. Compared to the DNPH-LC method, ACFAS method provided more reliable analytical results. In terms of convenience, easiness and analytical cost, ACFAS method was demonstrated to be superior to the DNPH-LC method. The results of this study suggested that the ACFAS method could be adapted as a proper method for determining formaldehyde content in drinking water.

• Journal of Hospice and Palliative Care
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• v.19 no.4
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• pp.322-330
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• 2016

Purpose: This study investigated long-term care hospital nurses' knowledge and practice of pain management and their attitudes towards the job with an ultimate aim to provide fundamental information for development of a pain education program. Methods: A cross-sectional survey was carried out with 120 nurses from four long-term care hospitals. Nurses' knowledge of and attitudes towards pain management was measured using a tool developed by Watt-Watson. To examine their pain management practice, an instrument was developed based on the pain management guidelines used by the long-term care settings. Results: For pain management knowledge, the participants gave an average of 26.2 (${\pm}13.10$) correct answers out of 40 questions. The most frequently missed question was one about subjectivity of pain, "Patients' physiological and behavioral reactions to pain hint at the presence and intensity of pain" (89.2%), and 56.7% of the nurses believed that increasing tolerance for a narcotic analgesic means addiction. Regarding attitudes towards and practice of pain management, 80.2% of the nurses used placebos to patients who complain about pain often. Conclusion: This study revealed poor level of pain management knowledge of and attitude among long-term care hospital nurses. This might negatively affect their pain management practice. From the educational perspective, nurses should be provided with education on pain management education with emphasis on the nature of pain and misuse of placebo drugs.

• Korean Journal of Acupuncture
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• v.34 no.4
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• pp.265-270
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• 2017

Objectives : The present study aimed to examine the analgesic effect of electroacupuncture(EA) applied to the brook point of the Liver meridian in the rat model of inflammatory pain and to investigate involvement of endogenouse opioid in the EA-induced analgesia. Methods : Knee arthritis was induced by injection of $125{\mu}l$ of complete Freund's adjuvant into the knee joint cavity unilaterally. To examine the level of pain, weight bearing forces(WBFs) of affected limb was measured. EA treatment was given at the LR2, LI4 or non-acupoint on the contralateral limb with frequency of 2 Hz and intensity of 2 mA under gaseous anesthesia. Results : After induction of arthritis, rats subsequently showed a reduced stepping force of the affected hindlimb due to a painful knee. EA applied to the LR2 point on the contralateral hind limb produced a significant improvement of stepping force of the hind limb lasting for at least 2 h, and this effect was equivalent to that obtained by 5 mg/kg of oral indomethacin. The effect of EA was specific to the acupoint since it could not be mimicked by EA applied to the LI4 point or the arbitrary non-acupoint. The analgesic effect was blocked by pretreatment with naltrexone(10 mg/kg, i.p.). Conclusions : These results suggest that acupuncture applied to LR2, brook point of Liver meridian suppresses inflammatory pain in a rat model of knee arthritis and this effect seems to be mediated by endogenous opioid systems.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.12 no.1
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• pp.49-53
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• 2012

X-linked adrenoleukodystrophy (ALD) is a rare inherited metabolic disease which results in impaired peroxisomal ${\beta}$-oxidation and the accumulation of very long chain fatty acids (VLCFA) in the adrenal cortex, the myelin of the central nervous system, and the testes. X-linked ALD is caused by mutations in the ABCD1 gene encoding an ATP-binding cassette transporter superfamily located in the peroxisomal membrane. This disease is characterized by a variety of phenotypes. The classic childhood cerebral ALD is a rapidly progressive demyelinating condition affecting the cerebral white matter before the age of 10 years in boys. We report the case of a 8-year-old with childhood cerebral X-linked ALD who developed inattention, hyperactivity, motor incoordination and hemiparesis. We diagnosed ALD with elevated plasma very long chain fatty acid level and diffuse high signal intensity lesions in both parieto-occipital white matter and cerebellar white matter in brain MRI. We identified a novel c.983delT (p.Met329CysfsX7) mutation of the ABCD1 gene. There is no correlation between X-ALD phenotype and mutations in the ABCD1 gene. Further studies for searching additional non-genetic factor which determine the phenotypic variation will be needed.

• Journal of Technology Innovation
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• v.26 no.1
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• pp.85-105
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• 2018

This study analyzes the economic impacts of Korean R&D expenditure on the industrial structure by technological levels using 2010~2014 Input-Output table data. The industrial structure is reclassified into 4 manufacturing industries by OECD's Technology Intensity Definition. Then, we analyzes the production-inducing and value added-inducing of those industries. As the results of the analysis, it is found that the production-inducing effect by the R&D expenditure has been higher in the middle-high and middle-low technology manufacturing and that the value added-inducing effect has been higher in the middle-high technology manufacturing. On the other hand, the production and value added-inducing effects has been lower in the high-tech manufacturing which is highest in the R&D expenditure. The above results indicate that industrial structure has not been linked with the quality ladder that expresses the enhancement of tech level through R&D expenditure. Based on these results, the policy recommendation implies that R&D expenditure should be concentrated to improve the production- and value-added effects of the high technology manufacturing in order to advance the industrial structure. However, this study has the limitation that the analyses on the dynamic-inducing effects are not carried out due to the lack of fixed capital formation data.

• Journal of Wetlands Research
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• v.14 no.2
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• pp.223-235
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• 2012

In this paper, field study results about accumulation of sediments and its property in the forebay of wetland aiming at stormwater from rural area wherein intensive cow feeding lots are operated are provided. In addition, some design aspects are discussed. Amount of sediment generation in the longitudinal direction of forebay was found to be affected by hydrological factors such as rainfall depth and intensity. Nutrient contents in the sediments of this wetland were 10 times higher than those in stormwater wetland in rural area without animal-feeding lot. Total-Pb and As contents show similar level to values from the soils of surrounding watershed, but Total-Cu content was higher due to the animal feeding lots. Yearly amount of sediment generation, its depth and volume were estimated to 13tons, 23cm, and $65m^3$. Based on these results and recommended guideline by Korean Ministry of Environment, dredging frequency was found to be about 2.7years. The shape of forebay has to be carefully designed to deal with a great change in flow rate. According to the results of sediment depth analysis, instead of the present rectangular, wedge-shape forebay is more desirable in handling scouring caused by high flows.

• Journal of the Korean association of regional geographers
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• v.19 no.3
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• pp.384-400
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• 2013

In this study, spatio-temporal patterns of extreme precipitation events caused by typhoons are examined based on observational daily precipitation data at approximately 340 weather stations of Korea Meterological Administration's ASOS (Automated Synoptic Observation System) and AWS (Automatic Weather System) networks for the recent 10 year period (2002~2011). Generally, extreme precipitation events by typhoons exceeding 80mm of daily precipitation commonly appear in Jeju Island, Gyeongsangnam-do, and the eastern coastal regions of the Korean Peninsula. However, the frequency, intensity and spatial extent of typhoon-driven extreme precipitation events can be modified depending on the topography of major mountain ridges as well as the pathway of and proximity to typhoons accompanying the anti-clockwise circulation of low-level moisture with hundreds of kilometers of radius. Yellow Sea-passing type of typhoons in July cause more frequent extreme precipitation events in the northern region of Gyeonggi-do, while East Sea-passing type or southern-region-landfall type of typhoons in August-early September do in the interior regions of Gyeongsangnam-do. These results suggest that when local governments develop optimal mitigation strategies against potential damages by typhoons, the pathway of and proximity to typhoons are key factors.

• Korean Journal of Environmental Biology
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• v.36 no.2
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• pp.117-123
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• 2018

In this study, the efficiency of photosynthetic electron transfer according to LED color temperature was verified in order to find a way to efficiently grow trees under night illumination. The experiment was carried out with White treatment, Warmwhite treatment, and non-treatment with donarium cherry. The study uses to a method for analyzing and evaluating the color temperature of an LED light source by photochemical analysis. We found that all treatments 115 DAT of maximum fluorescence amount(P) had the lowest. In the treatment using white light and the Warm-white light, the T amount of florescence of the late stage during the transition of the J-I level was increased, and the photosystem I electron transfer efficiency was decreased. Therefore, the electron transport efficiency of $RE1_O/CS$ and RE1o/RC were reduced. Especially, compared to Warmwhite, the light intensity increased greatly in the white-light treatment, The $PI_{TOTALABS}$ of 7 DAT was the highest value, but it was decreased to the lowest value on 115 DAT. This study has shown that the white treatment was low in electron transfer efficiency and soundness. Warmwhite-light treatments showed lower stress.

• Korean Journal of Food Science and Technology
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• v.12 no.3
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• pp.158-164
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• 1980

The quality of commercial milk was evaluated by sensory testing. The results were summarized as follows; 1. A significant difference on the quality and preference was not recognized at 5 percent level among the sample of commercial milk produced by five companies according to the result of rank test for commercial milk. 2. According to a scoring test for determination of shelf life of commercial milk A, the sensory quality of the sample milk was maintained for three days at $0^{\circ}C$ to $5^{\circ}C$ and $10^{\circ}C$ for one day at $20^{\circ}C$ and $30^{\circ}C$. 3. According to the result of profile test for commercial dried milk C, dilution number was 20.0 and sensory quality of the dried milk was comparatively satisfactory. 4. According to the result of profile test for commercial milk, the synthetics flavor of each milk was generally evaluated as excellent and the intensity of flavor was somewhat different among the samples of commercial milk produced by five companies. 5. A significant difference on the flavor of milk was recognized among five sample of commercial milk by both difference test and profile test but not recognized by rank test.

• Economic and Environmental Geology
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• v.46 no.6
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• pp.495-508
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• 2013

Recently, stable isotopes (${\delta}^{18}O$ and ${\delta}D$) of water are increasingly analyzed using laser-based technologies. These methods have advantages over Isotope Ratio Mass Spectrometry (IRMS) in that they can be used for in-situ measurements and require much less maintenance and preparation work. Two types of laser-based methods are currently available, which have different analytical principles; OA-ICOS (off-axis integrated cavity output spectroscopy) and WS-CRDS (wavelength-scanned cavity ring-down spectroscopy). In the WS-CRDS instrument, water is vaporized at controlled environment and transferred to an optical cavity by nitrogen carrier gas, and stable isotopic compositions of water vapor are measured using the degree of absorbance of specific wavelengths and the ratios of attenuation time of the laser intensity with the sensitivity of ppb to tens of ppt level. In this study, we introduce the principle of the WS-CRDS technology and the performance results including stability and comparisons with Isotope Ratio Mass Spectrometry (IRMS) and suggest possible applications of various topics in isotope hydrology.