• Title/Summary/Keyword: Integrated clinical database

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Extraction of Hierarchical Decision Rules from Clinical Databases using Rough Sets

  • Tsumoto, Shusaku
    • Proceedings of the Korea Inteligent Information System Society Conference
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    • 2001.01a
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    • pp.336-342
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    • 2001
  • One of the most important problems on rule induction methods is that they cannot extract rules, which plausibly represent experts decision processes. On one hand, rule induction methods induce probabilistic rules, the description length of which is too short, compared with the experts rules. On the other hand, construction of Bayesian networks generates too lengthy rules. In this paper, the characteristics of experts rules are closely examined and a new approach to extract plausible rules is introduced, which consists of the following three procedures. First, the characterization of decision attributes (given classes) is extracted from databases and the classes are classified into several groups with respect to the characterization. Then, two kinds of sub-rules, characterization rules for each group and discrimination rules for each class in the group are induced. Finally, those two parts are integrated into one rule for each decision attribute. The proposed method was evaluated on a medical database, the experimental results of which show that induced rules correctly represent experts decision processes.

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Ultrasonography for Facial Nerve Palsy: A Systematic Review and Meta-Analysis Protocol

  • Seojung Ha;Bo-In Kwon;Joo-Hee Kim
    • Journal of Acupuncture Research
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    • v.41 no.1
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    • pp.63-68
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    • 2024
  • Background: Facial nerve palsy presents a significant healthcare challenge, impacting daily life and social interactions. This systematic review investigates the potential utility of ultrasonography as a diagnostic tool for facial nerve palsy. Methods: Electronic searches will be conducted across various databases, including MEDLINE, EMBASE, CENTRAL (Cochrane Central register of Controlled Trials), CNKI (China National Knowledge Infrastructure), KMBASE (Korean Medical Database), ScienceON, and OASIS (Oriental Medicine Advanced Searching Integrated System), up to February 2024. The primary outcome will focus on ultrasonography-related parameters, such as facial nerve diameter and muscle thickness. Secondary outcomes will encompass clinical measurements, including facial nerve grading scales and electrodiagnostic studies. the risk of bias in individual study will be assessed using the Cochrane Risk of Bias assessment tool, while the grading of recommendations, assessment, development, and evaluations methodology will be utilized to evaluate the overall quality of evidence. Conclusion: This study aims to review existing evidence and evaluate the diagnostic and prognostic value of ultrasonography for peripheral facial nerve palsy.

Review on Fukuda Stepping Test, Its Procedures and Criteria for the Evaluation of the Postural Balance Control (자세음양 균형검사로서 Fukuda Stepping Test에 대한 문헌적 고찰)

  • Bae, Jin Yong;Lee, Jaemin;Lee, Gyeong Ran;Lee, Young Jun;Yin, Chang Shik
    • Journal of TMJ Balancing Medicine
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    • v.4 no.1
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    • pp.5-7
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    • 2014
  • Objectives: Neurological examination on balance function is widely applied in clinical practice. Balance function may be clinically relevant to an assessment of yinyang balance in such therapies as temporomandibular joint balancing medicine. Fukuda stepping test is a relatively not-well-known method of balance function test. This study reviewed the procedures and criteria of Fukuda stepping test. Method: Recent articles on Fukuda stepping test were searched in public database (Pubmed, Proquest) and reviewed for its procedures and clinical implications. Results: Fukuda stepping test adopts 50 steps or 100 steps with subsequent assessment of the deviation or displacement of the subject. It may not be reliable during acute phase. Conclusion: Fukuda stepping test may be utilized and be further developed to assess balance function in the neurological management of functions.

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An Analysis of Physicians' Online Information Search Process at the Point of Care (의사의 임상질문 해결을 위한 온라인 정보검색과정 연구)

  • Kim, Soon;Chung, EunKyung
    • Journal of the Korean Society for information Management
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    • v.33 no.3
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    • pp.177-193
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    • 2016
  • This study aims to analyze physicians' online information search process to solve the clinical questions at the point of care. To achieve this purpose, ten university hospital-based physicians participated in-depth interviews and observation studies. Based on Wilson's problem solving process, this study analyzed the characteristics of each information search stage and efficiency of online searching. The results showed that participants tend to relatively immediately formulate their clinical questions. However, basic searching strategies were only used and a few preferred information sources were chosen. However, average satisfaction degree of online searching appeared high with 5.7 (7 Likert-scale) and problem-solving index increased after searching. As physicians are likely to use well organized and evidenced-based credible information easily, it implies the needs for an integrated search system within the electronic medical record (EMR). In addition, as other online resources' awareness is lower comparing Google and PubMed, active promotions and training of other resources are needed.

Systematic Review of Korean Medicine-related Study on Diagnostic Tools and Pattern Identification registered of Dysmenorrhea in the Korean Journal (국내 전자저널에 수록된 월경통 평가지표 및 변증에 대한 한의학적 임상연구 고찰)

  • Kim, Jihye;Kim, Jongyeol;Jeon, Youngju
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.29 no.5
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    • pp.434-442
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    • 2015
  • The purpose of this review was to survey the Korean Medicine related papers about women with primary dysmenorrhea in order to develop the clinical protocol of the diagnostic medical device. We searched the literature from 2000 through April 2015 using 5 online databases including Oriental Medicine Advanced Searching Integrated Sysptem (OASIS), Research Information Sharing Service (RISS), DataBase Periodical Information Academic (DBpia) and Korean Medical Database (KMBase). We selected papers to meet the following inclusion criteria: the papers involved dysmenorrhea (excluding secondary dysmenorrhea), published papers (excluding textbook, educational materials, conferences, etc.) and the papers matched search keywords or scope, but excluded papers to meet the following exclusion criteria: the duplicative papers, get out of the keywords and scope and not in english or korean language. Finally we found 17 papers and classified the papers according to the three search purposes which were diagnostic tools for evaluating the menstrual pain, dysmenorrhea' pattern identification and menstrual phase. Out of the 16 studies, 4 studies were focused on the diagnostic tools including Visual Analogue Scale (VAS), Measurement of Menstrual Pain (MMP) and etc. Other 5 studies were aimed at menstrual phase, and the other 7 studies were studied for pattern identification. The VAS has been widely used in research and in clinical practice for the detection of the menstrual pain. Treatments for patients with primary dysmenorrhea can be prescribed in consideration of their patterns of sasang constitution or body constitution as following: Qi stagnation-Blood deficiency, cold dampness, Qi deficiency-blood deficiency and liver-kidney deficiency etc. This results of research will be used as a useful material during plan a clinical study of primary dysmenorrhea and acquisition of good clinical data.

Analysis of Pharmacogenetic Information in Korea Drug Labels (국내 허가사항에 반영된 약물 유전정보 분석)

  • Lee, Mijin;Kim, Sukyung;Yee, Jeong;Gwak, Hye Sun;Choi, Kyung Hee
    • Korean Journal of Clinical Pharmacy
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    • v.31 no.1
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    • pp.21-26
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    • 2021
  • Background: Pharmacogenomics is the study of how genetic mutations in patients affect their response to drugs. Pharmacogenomic studies aim to maximize drug effects and minimize adverse drug events. The Food and Drug Administration and the European Medicine Agency published guidelines for pharmacogenetics in 2005 and 2006, respectively; the Korean Ministry of Food and Drug Safety followed suit in 2015. Methods: This study analyzed pharmacogenomic information in the Korean Ministry of Food and Drug Safety's integrated drug information system to evaluate whether domestic pharmaceutical products reflect the current research on pharmacogenomic differences. Results: In June 2020, the Korean pharmacogenomic database contained genomic data on 90 compounds. Of these, 45 compounds were classified as "Antineoplastic and immunomodulating agents." The other 45 non-antineoplastic agents were in the following categories: Anti-infectives, Mental & behavior disorder, Hormone & metabolism related diseases, Cardiovascular system, Skin & subcutaneous tissue disease, Genito-urinary system and sex hormones, Blood and blood forming organs, Nervous system, Alimentary tract and metabolism, Musculo-skeletal system, and Other conditions including the respiratory system. In addition, 30 additives unrelated to the main ingredient were associated with genetic precautions. Conclusion: This study showed that antineoplastic and immunomodulating agents accounted for half the drugs associated with pharmacogenetic information. For antitumor and immunomodulatory drugs, genomic tests were recommended depending on the indication; this was in contrast to genomic testing recommendations for non-antineoplastic medications. Genomic tests were rarely requested or recommended for non-antineoplastic medications because the relationships between genotype and efficacy among those drugs were relatively weak.

An Analysis of Clinical Research Trends on Interventions of Korean Medicine for Ovarian Cysts (난소 낭종의 한의학적 치료에 대한 국내 임상연구 동향 분석)

  • Jeoung-Yoon Choi;Jin-Moo Lee;Chang-Hoon Lee;Jun-Bock Jang;Deok-Sang Hwang
    • The Journal of Korean Obstetrics and Gynecology
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    • v.36 no.3
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    • pp.25-45
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    • 2023
  • Objectives: The purpose of this study is to review the clinical research trends of ovarian cysts and to recognize the efficacy of Korean medicine intervention. Methods: Based on four domestic databases, including Korean studies Information Service System (KISS), Oriental Medicine Advanced Searching Integrated System (OASIS), Korean Medical Database (KMbase) and Research Information Sharing Service (RISS), we analyzed the case reports using Korean medicine intervention, which include acupuncture, moxibustion and herbal medicine. Data retrieval was carried out from May 12th, to 18th, 2022, and a total of 9 papers were included. Results: All papers were published in Korea and they contain seventeen case reports in total. The most frequently used intervention was herbal medicine, especially Gyejibokryeong-hwan-gami (桂枝茯苓丸加味), Guichulpajing-tang-gagam (歸朮破癥湯加減), Guibiondam-tang-gami (歸脾溫膽湯加味). Most cases reported statistically significant results on using Korean-medicine intervention. Also, there was no serious side effect of Korean medicine. Conclusions: In this study, we investigated the efficacy of Korean medicine intervention as an adjuvant therapy for ovarian cyst patients and research trends on ovarian cysts. Further studies are needed to supplement the safety and the evaluation of Korean medicine. However, the results should be taken cautiously as more clinical studies are needed.

Comparison between domestic and foreign Clinical guidelines and previous researches on Korean medicine for psoriasis to develop the clinical trial guideline of psoriasis using Korean medicine (건선 한약제제 임상시험 가이드라인 개발을 위한 관련 국내외 가이드라인과 기존 건선치료 한약제제 연구와의 비교)

  • Kang, Se Hyun;Moon, Young-Kyun;Jeong, Woo-Yeol;Nam, Hae-Jung;Kim, Yoon-Bum;Lee, Jun-Hee;Kim, Kyuseok
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.29 no.2
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    • pp.12-32
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    • 2016
  • Objectives : The objective of this study is to develop the strategies of the psoriasis clinical trials guideline on Korean medicine by comparison between Clinical guidelines and domestic and foreign clinical trials papers of psoriasis on Korean medicine. Methods : This study is based on analysis of papers on Clinical trials guidelines, Clinical practice guideline and clinical trials about Korean medicine. The papers were searched from Pubmed, Medline, Oasis(Oriental Medicine Advanced Searching Integrated System), Korean Traditional Knowledge Portal and Google portal database. Results : A total 8 Clinical practice guidelines and 2 Clinical trials guidelines were found. Moreover, there were 15 foreign papers about clinical trials and 29 internal articles about case studies. They suggested the diagnostic strategy, classification, effective outcome measure, severity measure, precaution of combination therapy, precaution and treatment period of clinical trials, safety evaluation, patterns of Korean Medicine, clinical specific features on psoriasis.Conclusions : The criteria of every item to provide the clinical trials guideline using Korean medicine on psoriasis were developed by apply the results. If we accumulate the more clinical articles on Korean medicine, it will be great help to develop the reliable standard of that guideline.

Evaluation of Adherence to the CARE (CAse REport) Guidelines of Case Reports in the Journal of Korean Medicine Rehabilitation (한방재활의학과학회지에 게재된 증례보고의 CARE (CAse REport) 지침 준수에 대한 평가: 2016년 이후 발표된 논문들을 중심으로)

  • Ahn, Jonghyun;Ko, Junhyuk;Kim, Seyoon;Kim, Soojeon;Bae, Jun-hyeong;Yoon, Ye-ji;Lee, Hansol;Chang, Hokyung;Kim, Hyungsuk;Chung, Seok-hee;Lee, Jong-soo;Kim, Sung-soo;Chung, Won-Seok
    • Journal of Korean Medicine Rehabilitation
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    • v.29 no.3
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    • pp.75-85
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    • 2019
  • Objectives This study was perfomed to assess the adherance to CARE (CAse REport) guideline of case reports in the Journal of Korean Medicine Rehabilitation Methods We searched the case reports published in the Journal of Korean Medicine Rehabilitation from January 2016 to April 2019 in the database of oriental medicine advanced searching integrated system (OASIS). Then we evaluated the quality of the searched case reports based on the CARE guideline. Results Totally 31 papers were selected after the screening the case reports by the inclusion and exclusion criteria. The report rate of the sub-items of the CARE guideline was 78.26% at the maximum, 60.87% at the maximum, and 70.97% on the average. The following items were reported only in less than 50% of them; 'Timeline', 'Diagnostic challenges', 'Diagnostic reasoning including other diagnoses considered' 'Prognostic characteristics', 'Follow-up and Outcomes', 'Patient Perspective', 'Informed Consent' Conclusions This study is expected to contribute to the overall improvement of the level of case reports in the Journal of Korean Medicine Rehabilitation.

The effect of motor learning in children with cerebral palsy: A systemic review (뇌성마비 아동의 운동학습 효과 체계적 고찰)

  • Kim, Jung-Hyun
    • Journal of Korean Physical Therapy Science
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    • v.28 no.1
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    • pp.33-45
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    • 2021
  • Background: Children with cerebral palsy have difficulty acquiring motor skills through motor learning due to lack of motor planning of the central nervous system and musculoskeletal dysfunction. Motor learning is the acquisition or modification of movements with the aim of developing skilled movements and behaviors. Cerebral palsy improve motor function through motor learning, and effective motor learning mainly depends on practice parameters such as learning feedback. Therefore, we investigate the effect of motor learning in children with cerebral palsy and try to present the possibility of clinical application. Design: A systemic review. Methods: Research papers were published from Jan, 2010 to Dec, 2020 and were searched using PubMed and Medline. The search terms are 'task specific training' OR 'motor learning' OR 'feedback(Mesh term)' OR 'goal activity' AND 'cerebral palsy(Mesh term)'. A total of eight papers were analyzed in this study. The paper presented the quality level based on the research evidence, and also presented PEDro (Physiotherapy Evidence Database) scores to evaluate the quality of design studies in randomized clinical trials. Results: The results showed that motor learning coaching in children with cerebral palsy improved motor function in post and follow up tests. Also, self-control feedback of motor learning is more effective than external control feedback. 100% external control feedback of motor learning is effective in the acquisition phase and 50% external feedback of motor learning is effective in the retain phase. Conclusion: These results suggest that it will be an important data for establishing evidence on the effect of motor learning arbitration methods in children with cerebral palsy to develop clinical applicability and protocols.