• Title/Summary/Keyword: Integrated M&S

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A Study on the Design and Structural analysis of High Integrated Tool Tower ATC for Machine Tool (공작기계용 고 집적형 Tool Tower ATC 설계 및 구조 해석에 관한 연구)

  • Lee C.M.;Lim S.H.;Roh Y.H.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2005.10a
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    • pp.551-554
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    • 2005
  • This study is concerned about the design and structural analysis of high integrated tool tower ATC(Automatic Tool Changer) for machine tool. Recently, many studies have been undergoing to reduce a working time in a field of machine tool. Tool tower ATC belongs to reduce a stand-by time by shortening a tool exchanging time. The developed system can store more number of tool in small space than other machine. The analysis is carried out by CATIA V5 software. In the result of structural analysis, the safety factor of the developed system is confirmed.

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The Relationship between Prohibitin 1 Expression, Hepatotoxicity Induced by Acetaminophen, and Hepatoprotection by S-Adenosylmethionine in AML12 Cells

  • Eunhye Cho;Soohan Jung;Jina Kim;Kwang Suk Ko
    • Journal of Microbiology and Biotechnology
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    • v.32 no.11
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    • pp.1447-1453
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    • 2022
  • Prohibitin 1 (Phb1) is a pleiotropic protein, located mainly in the mitochondrial inner membrane and involved in the regulation of cell proliferation and the stabilization of mitochondrial protein. Acetaminophen (APAP) is one of the most commonly used over-the-counter analgesics worldwide. However, at high dose, the accumulation of N-acetyl-p-benzoquinone imine (NAPQI) can lead to APAP-induced hepatotoxicity. In this study, we sought to understand the regulation of mRNA expression in relation to APAP and GSH metabolism by Phb1 in normal mouse AML12 hepatocytes. We used two different Phb1 silencing levels: high-efficiency (HE, >90%) and low-efficiency (LE, 50-60%). In addition, the siRNA-transfected cells were further pretreated with 0.5 mM of Sadenosylmethionine (SAMe) for 24 h before treatment with APAP at different doses (1-2 mM) for 24 h. The expression of APAP metabolism-related and antioxidant genes such as Cyp2e1 and Ugt1a1 were increased during SAMe pretreatment. Moreover, SAMe increased intracellular GSH concentration and it was maintained after APAP treatment. To sum up, Phb1 silencing and APAP treatment impaired the metabolism of APAP in hepatocytes, and SAMe exerted a protective effect against hepatotoxicity by upregulating antioxidant genes.

Planning for the Yeonin Mountain Provincial Park (연인산 도립공원 조성계획)

  • Lee, Jun-Bok
    • Journal of the Korean Institute of Landscape Architecture
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    • v.35 no.1 s.120
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    • pp.9-19
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    • 2007
  • This plan was submitted as part of an invited competition for the provincial park planning of Yeonin Mountain, which was held by the Gyeonggi Innovation Corporation in November, 2006. The proposed site is located at Seungan-ri, Gapyung-eup, Gapyung-gun, Gyunggi-do and covers about $150,010m^2$. The main goal of this project is to "Suggest a New Park Paradigm" by shedding old ways of thinking about parks through an integrated development concept. Planning was approached as follows: First, providing an unique theme to the support facilities area of Yeonin Mountain Piovincial Park. To achieve this theme, the Seungan support facilities area was designated to be home to a Seven Colored Theme Garden, currently named the Native Wild-flower Garden, while the Baekdun facilities area is to be centered on a Self-loaming Forest Camp, which will give the chance of a hands-on wildlife experience. With these themes, which create recreational goals that will encourage not only tourism but education as well, the foundation was laid for a multi-purpose park paradigm. Second, Developing a Core Facility Zone. To accomplish the development of a core facility zone, park buildings will be arranged in accordance with an integrated building lay-out for easy access and use, and the facilities specified by design for the Seven Colored Theme Garden are provided for the newly prepared site. This will allow focus on the user's viewpoint instead of the view of the planner or of ease of maintenance.

A Study on the Structural Analysis & Design Optimization Using Automation System Integrated with CAD/CAE (통합된 CAD/CAE 자동화 System을 이용한 구조강도해석 및 설계최적화에 관한 연구)

  • Yoon J.M.;Won J.H.;Kim J.S.;Choi J.H
    • Korean Journal of Computational Design and Engineering
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    • v.11 no.2
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    • pp.128-137
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    • 2006
  • In this paper, a CAD/CAE integrated optimal design system is developed, in which design and analysis process is automated using CAD/CAE softwares for a complex model in which the modeling by parametric feature is not easy to apply. Unigraphics is used for CAD modeling, in which the process is automated by using UG/Knowledge Fusion for modeling itself and UG/Open API function for the other functions respectively. Structural analyses are also carried out automatically by ANSYS using the imported parasolid model. The developed system is applied for the PLS(Plasma Lighting System) consisting of more than 20 components, which is a next generation illumination system that is used to illuminate stadium or outdoor advertizing panel. The analyses include responses by static, wind and impact loads. As a result of analyses, tilt assembly, which is a link between upper and lower body, is found to be the most critical component bearing higher stresses. Experiment is conducted using MTS to validate the analysis result. Optimization is carried out using the software Visual DOC for the tilt assembly to minimize material volume while maintaining allowable stress level. As a result of optimization, the maximum stress is reduced by 57% from the existing design, though the material volume has increased by 21%.

Novel Rate Control Scheme for Low Delay Video Coding of HEVC

  • Wu, Wei;Liu, Jiong;Feng, Lei
    • ETRI Journal
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    • v.38 no.1
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    • pp.185-194
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    • 2016
  • In this paper, a novel rate control scheme for low delay video coding of High Efficiency Video Coding (HEVC) is proposed. The proposed scheme is developed by considering a new temporal prediction structure of HEVC. In the proposed scheme, the relationship between bit rate and quantization step is exploited firstly to formulate an accurate quadratic rate-quantization (R-Q) model. Secondly, a method of determining the quantization parameters (QPs) for the first frames within a group of pictures is proposed. Thirdly, an accurate frame-level bit allocation method is proposed for HEVC. Finally, based on the proposed R-Q model and the target bit allocated for the frame, the QPs are predicted for coding tree units by using rate-distortion (R-D) optimization. We compare our scheme against that of three other state-of-the-art rate control schemes. Experimental results show that the proposed rate control scheme can increase the Bjøntegaard delta peak signal-to-noise ratio by 0.65 dB and 0.09 dB on average compared with the JCTVC-I0094 and JCTVC-M0036 schemes, respectively, both of which have been implemented in an HEVC test model encoder; furthermore, the proposed scheme achieves a similar R-D performance to Wang's scheme, as well as obtaining the smallest bit rate mismatch error of all the schemes.

CuO Nanograss as a Substrate for Surface Enhanced Raman Spectroscopy

  • Lee, Jun-Young;Park, Jiyun;Kim, Jeong-Hyun;Yeo, Jong-Souk
    • Proceedings of the Korean Vacuum Society Conference
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    • 2013.08a
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    • pp.249-249
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    • 2013
  • Surface-enhanced Raman spectroscopy (SERS) is a sensitive approach to detect and to identify a variety of molecules. To enhance the Raman signal, optimization of the gap between nanostructures is quite important. One-dimensional materials such as nanowires, nanotubes, and nanograsses have great potential to be used in SERS due to their unique sizes and shape dependent characteristics. In this study we investigate a simple way to fabricate SERS substrates based on randomly grown copper oxide (CuO) nanowires. CuO nanograss is fabricated on pre-cleaned Cu foils. Cu oxidized in an ammonium ambient solution of 2.5 M NaOH and 0.1 M $(NH_4)_2S_2O_8$ at $4^{\circ}C$ for 10, 30, and 60 minutes. Then, Cu(OH)2 nanostructures are formed and dried at $180^{\circ}C$ for 2 h. With the drying process, the Cu(OH)2 nanostructure is transformed to CuO nanograss by dehydration reaction. CuO nanograss are grown randomly on Cu foil with the average length of 10 ${\mu}m$ and the average diameter of a 100 nm. CuO nanograsses are covered by Ag with various thicknesses from 10 to 30 nm using a thermal evaporator. Then, we immerse uncoated and Ag coated CuO nanowire samples of various oxidation times in a 0.001M methanol-based 4-mercaptopyridine (4-Mpy) in order to evaluate SERS enhancement. Raman shift and SERS enhancement are measured using a Raman spectrometer (Horiba, LabRAM ARAMIS Spectrometer) with the laser wavelength of 532 nm. Raman scattering is believed to be enhanced by the interaction between CuO nanograss and Ag island film. The gaps between Ag covered CuO nanograsses are diverse from <10 nm at the bottom to ~200 nm at the top of nanograsses. SERS signal are improved where the gaps are minimized to near 10s of nanometers. There are many spots that provide sufficiently narrow gap between the structures on randomly grown CuO nanograss surface. Then we may find optimal enhancement of Raman signal using the mapping data of average results. Fabrication of CuO nanograss based on a solution method is relatively simple and fast so this result can potentially provide a path toward cost effective fabrication of SERS substrate for sensing applications.

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Temperature-Dependence of Poly-Si Thin film Transistors (다결정 실리콘 박막 트랜지스터의 온도 의존성)

  • 이정석;이용재
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 1999.05a
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    • pp.403-406
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    • 1999
  • The influence of temperature variation (25~125$^{\circ}C$) on poly-Si thin-film transistors (TFT's) was investigated by examining the electrical properties change of poly-Si films formed by solid phase crystallization (SPC). The n-channel poly-Si TFT's fabricated by SPC with channel length of 1.5 and loon ,respectively, exhibit good characteristics with a high ${\mu}$$\sub$FE/ ($\geq$82 and $\geq$60$\textrm{cm}^2$/V-s in 1.5 and 10$\mu\textrm{m}$, respectively), low V$\sub$t/, ($\leq$1.52 and $\leq$ 2.75V in 1.5 and 10$\mu\textrm{m}$, respectively), low S$\sub$t/, and good ON-OFF characteristics in spite of temperature variation. Thus, poly-Si films formed by SPC can be applied for the application to poly-Si TFT liquid crystal display with peripheral integrated circuits.

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A Study on Constructing the Integrated Collaborate Environment for Simulation Based Acquisition (SBA(Simulation Based Acquisition)를 위한 통합협업환경 구축에 관한 연구)

  • Lee, Seung-Hun;Son, Min-Woo;Shin, Dong-Il;Shin, Dong-Kyoo
    • Proceedings of the Korean Information Science Society Conference
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    • 2008.06b
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    • pp.101-104
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    • 2008
  • 국방 획득절차를 과학화하기 위해 소요제기에서 연구개발, 시험평가, 운영유지에 이르는 무기체계 획득 전 순기에 걸쳐 M&S 도구를 효과적으로 활용할 수 있도록 하는 SBA 통합협업환경 구축이 필요하다. 그 동안 국내 무기체계 개발 기술은 비약적인 발전을 거듭해 왔다. 하지만 무기체계 획득을 위한 통합지원체계 및 통합협업환경에 대한 연구는 활발히 진행되지 않고 있다. 본 논문은 SBA 통합협업환경 아키텍처를 설계하기 위해 SBA및 M&S의 개념과 SBA 통합협업환경 구성기술들을 알아보고 구성기술들을 조합하여 SBA 통합협업환경 아키텍처를 설계한다.

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ON THE ORDER OF SPECIALITY OF A SIMPLE, SPECIAL, AND COMPLETE LINEAR SYSTEM ON A CURVE

  • Ballico, Edoardo;Homma, Masaaki;Ohbuchi, Akira
    • Journal of the Korean Mathematical Society
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    • v.39 no.4
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    • pp.593-609
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    • 2002
  • The order of speciality of an ample invertible Sheaf L on a curve is the least integer m so that $L^{ m}$ is nonspecial. There is a reasonable upper bound of the order of speciality for a simple invertible sheaf in terms of its degree and projective dimension. We study the case where it reaches the upper bound. Moreover we for mulate Castelnuovo's genus bound involving the order of speciality.ality.