• Journal of vocational education research
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• v.35 no.4
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• pp.109-129
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• 2016

Korea has recently invested much of its effort in fostering talents in scientific fields to establish a foundation for sustainable future growth. From this perspective, the ministry of education has come up with a special rule aimed at achieving the substantiality of engineering schools in universities. The ministry has been providing educational support by providing a tech-innovation center, industry-oriented education, and policies such as PRIME. Despite this support, most students in the natural science field end up being hired in fields not related to their majors. There has been a growing opinion regarding the need for career education for these students. In this research, based on a social cognitive career theory (SCCT) model that provides a comprehensive understanding of career development, this research would like to practically examine the relationship among college students' career preparation behaviors and influencing variables, such as grit, career decision-making self-efficacy, outcome expectation, and major interest. Data from 153 natural-science majors at A college in Korea were collected and analyzed using path analysis. The result was that the data strongly supported the model explaining the relationship between career preparation behaviors and influencing variables. Based on this result, we propose that career education that can promote grit, career decision-making self-efficacy, outcome expectation, and major interest is required to encourage students in the field of the natural sciences to pursue career preparation behaviors related to their majors.

• The Korean Journal of Archival Studies
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• no.18
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• pp.91-138
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• 2008

A fast foot of information communication technology is appearing as expansion of prompt administrative service desire and national participation desire regarding administration. This is following again by government innovation and demand of customer-oriented governmental implementation with information technology. The Ministries of Education and Human Resources Development proceeded with National Education Information System(NEIS) for the aim of educational informatization at a highest global level. NEIS that was operated from 2003 established a system in Educational Offices in 16 cities/province and the Ministry of Education and Human Resources Development, and connected all educational administration organizations and primary and middle schools with Internet. Thus, NEIS processes electronically the general administration affairs in educational administration organizations each unit school. The NEIS school affairs business system that is newly enforced is producing an important documentation (of semi-permanent level) such as personal information and grade of students including School Human Document with electronic methods. However, we need to guarantee authenticity, integrity, reliability and usability of documentation because school affairs business system is producing important documentation under poor circumstances. According to this necessity, school affairs business system analyzed how many a record management function includes by the ISO 15489 that was an international record managerial standard. On the basis of these analyses, I will present a plan for management of a school documentation in this study. These researches are meaningful in electronically analyzing a record management function of the National Education Information System(NEIS) and in documentarily approaching management plan. I expect theses researches to be able to used as useful data for documental management plan preparations regarding a productive documentation of all kinds of business systems using in public institutions as well as National Education Information System(NEIS).

• International Area Studies Review
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• v.16 no.3
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• pp.3-25
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• 2012

This study is to look at the relationship of entrepreneurship(innovativeness, risk-taking), the learning competence, environmental factors(the domestic market hostility, the speed of technological change) and export performance in international new ventures(INVs). In addition, the integrated model is constructed for the purpose of analysis of the moderating effects of environmental factors. Through the existing investigation, nine hypotheses are set up. PLS(Partial Least Square) analysis method is used to sample of 115 INVs. Analysis, the two elements of entrepreneurship influenced the positive(+) in the learning competence and export performance. And the relationship of learning competence and export performance is significant. In the moderating effects, only the domestic market hostility has a significant moderating effects between the learning competence and innovativeness. The results of this research shows that innovativeness influence the learning competence playing a positive role in the performance in the domestic market is higher. This point illustrates the practical implications of the importance of innovation in learning empowerment.

• The Korean Journal of Vision Science
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• v.20 no.4
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• pp.589-596
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• 2018

Purpose : We compared intraocular pressure (IOP) values measured by two types of tonometers in condition of normotensive and glaucomatous rat model. We tried to determine which of tonometer can more easily and accurately measure the IOP of animal model. Methods : Glaucomatous eyes were induced by intracameral injections of hyaluronic acid in right eyes of six-week-old male Spargue-Dawley (SD) rats. Normotensive contralateral eyes were left eyes of the SD rats. IOP was measured using a rebound tonometer (Tonolab) and a immersive tonometer ($Tonopen^{(R)}$ XL) about 3:00 pm. Results : The mean IOP values of normotensive control eyes were $10.80{\pm}1.03mmHg$ by Tonopen, and $15.10{\pm}0.73mmHg$ by Tonolab. They were statistically insignificant (p = .1). The mean IOP values of glaucomatous experimental eyes were $30.20{\pm}2.67mmHg$ by Tonopen, and $37.90{\pm}2.73mmHg$ by Tonolab. They were statistically insignificant (p = .95). High IOP values of glaucomatous eyes by two types of tonometers had strong positive correlation each other (r = .904, p < .01). Conclusion : This is the first study to compare IOP values using two types of tonometers between normotensive and glaucomatous model made by intracameral injection of hyaluronic acid. Tonopen should be used carefully when the IOP is within normal range, and both Tonopen and Tonolab can be used reliably when the IOP is high.

• Journal of Life Science
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• v.29 no.7
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• pp.809-816
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• 2019

The ubiquitous plant metabolite p-coumaric acid (p-CA) has antioxidant and anti-inflammatory properties, but its anti-cancer activity has not been established in gastric cancer cell lines. In this study, we investigated the effects of p-CA on the proliferation and transcriptome profile of SNU16 gastric cancer cells. Treatment with p-CA induced apoptosis of the SNU-16 cells by regulating the expression of pro-apoptotic and anti-apoptotic proteins, such as Bcl-2, poly (ADP-ribose) polymerase (PARP), Bax, procaspase-3, and cleaved-caspase-3. The genes differentially expressed in response to p-CA treatment of the SNU-16 cells were identified by RNA sequencing analysis. Genes regulated by p-CA were involved mainly in the inflammatory response, apoptotic processes, cell cycle, and immune response. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis indicated that the phosphatidylinositol-3-kinase-Akt and cancer signaling pathways were altered by p-CA. Protein-protein interaction (PPI) network analysis also revealed that p-CA treatment was correlated with differential expression of genes associated with the inflammatory response and cancer. Collectively, these results suggest that p-CA has potential utility in gastric cancer prevention.

• Journal of the Economic Geographical Society of Korea
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• v.21 no.4
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• pp.303-320
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• 2018

This study analyzes the characteristics of the evolution process of the Gumi National Industrial Complex as well as its external and internal drivers based on the cluster adaptation cycle model. The Gumi National Industrial Complex has made remarkable progress through expansion in spatial and industrial realm and has become a representative IT industry cluster in Korea. It evolved during a growth period from the 1990s, a maturity period from the mid-2000s, and a mature stagnation period from the mid-2010s. But it has now entered a period of decline. While external drivers at the international and national level greatly influenced the Gumi National Industrial Complex in its evolution from foundation-building to maturity, internal drivers such as the outflow of large firms as well as a lack of SME research capacity and institutional base have added to the management difficulties of SMEs in the mature stagnation period. Therefore, in order for the Gumi National Industrial Complex to move into a revitalization period that strengthens resilience against external shocks, it is necessary to enhance the capacity of SMEs by expanding the roles of the central government, local government, and support agencies. In addition, it is necessary to create and embed strong medium enterprises within the Gumi National Industrial Complex, so that the Complex can be reborn as a sustainable innovation ecosystem.

• The Journal of Society for e-Business Studies
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• v.24 no.1
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• pp.29-48
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• 2019

Recently, product design innovation to improve user experience has been perceived as a core element of enterprise competitiveness due to the fierce market competition and decrease of the technological gap between companies, but there is insufficient services to support the product experience evaluation of small and medium-sized companies (SMCs). The aim of this study is to develop a web-based product user experience evaluation and certification system supporting product design practices for SMCs. For system interface design, we conducted systematic functional requirement elicitation methods such as user survey, workflow analysis, user task definition, and function definition. Then main functions, information structure, navigation method, and detailed graphic user interfaces were developed with consideration of user interactions and requirements. In particular, it provides the databases for evaluation efficiency to support the evaluation process above a certain level of performance and efficiency, and knowledge databases to utilize in the evaluation and product design improvement. With help of the developed service platform, It is expected that the service platform would enhance SMCs' product development capability with regard to the user experience evaluation by connecting the consulting firms with SMCs.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.14 no.3
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• pp.13-26
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• 2019

There is a growing interest in the entrepreneurial activity that has long been considered essential for sustainable economic development and value creating. Although it is strongly encouraged by focusing on the positive aspects of venturing, less has been paid attention to entrepreneurial failure, which is the biggest cause of hesitation in starting a business. The uncertain and risky nature of entrepreneurship implies a considerable possibility of failure. Even if it fails, the experience and knowledge of entrepreneurs acquired through entrepreneurship indeed offers valuable lessons for the re-venturing, which can serve as an important social asset that should not be lost. It has been argued that re-entering the same industry for the subsequent venture maximizes the learning effect through utilizing potential benefits from industry-specific knowledge. Although the re-startup after entrepreneurial failure is a very important topic in the studies on serial entrepreneurs, there is a paucity of systematic empirical investigation. This study responds to calls for more research on the re-startup after entrepreneurial failure, and specifically complements existing studies on serial entrepreneurs. Focusing on the entrepreneurs' attribution for the failure, we conducted an empirical analysis of how this affects the re-startup process. Moreover, we also examined the moderating effects of entrepreneurial self-efficacy and resilience. For the analyses, we surveyed the entrepreneurs who tried to re-start the subsequent business after the entrepreneurial failure through the "Revitalization Center for Strained Entrepreneur". The results found that failed entrepreneurs who blamed internal factors for their previous venture failures were likely to keep the same industry for their subsequent business. In addition, the positive effect of internal attribution on maintaining the same industry for the re-startup was found to be stronger when entrepreneurial self-efficacy and resilience were high.

• Korea and Global Affairs
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• v.3 no.1
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• pp.77-106
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• 2019

The purpose of this paper is to propose measures to respond to NK's nuclear threat by applying the concept of offset strategy in the US and the fourth industrial revolution technology innovation. Through this study, the concept, technology, and organization were examined to find measures to counter the NK's nuclear threat. The concept was to review the US offset strategy and consider the strategy of paralyzing the enemy's center as an operational concept. And the technologies that can support the 4th Industrial revolution and the 3rd US offset strategy. The organization analyzed the implications for the reform of the National Defense Reform 2.0 and the reorganization of the acquisition of the US DoD. Through the US offset strategy review, it is necessary to reconcile the strategic concepts of Korea and the US, and the interoperability of technologies and the cooperation fields of the ROK-US alliance. In addition, it is necessary to strengthen the capability of responding to NK's nuclear threat in connection with the 4th Industrial Revolution and the National Defense Reform 2.0 promotion. It is necessary to develop the concept of operational performance applying the new paradigm for the NK's nuclear issue and to apply advanced science and technology. And that it is necessary to organize effectively in conjunction with the National Defense Reform 2.0.

• Korean Journal of Clinical Laboratory Science
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• v.51 no.2
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• pp.221-234
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• 2019

Cancer is genetically, metabolically and infectiously induced life threatening disorder showing aggressive growing pattern with invasive tendency. In order to prevent this global menace from jeopardizing human life, enormous studies on carcinogenesis and treatment for chemotherapy resistance have been intensively researched. Hinokitiol (${\beta}$-thujaplicin) extracted from heart wood of cupressaceous is a well-known bioactive compound demonstrating anti-inflammation, anti-bacteria and anti-cancer effects on several cancer types via apoptosis and autophagy. This study proposed that hinokitiol activates transcription factor EB (TFEB) nuclear translocation for autophagy and lysosomal biogenesis regardless of nutrient condition in cancer cells. Mitophagy and ${\beta}$-catenin translocation into the nucleus under treatment of hinokitiol on non-small cell lung cancer (NSCLC) cells and HeLa cells were investigated. Hinokitiol exerted cytotoxicity on HeLa and HCC827 cells; moreover, artificially induced autophagy by overexpression of TFEB granted imperfect sustainability onto HeLa cells. Taken together, hinokitiol is the prominent autophagy inducer and activator of TFEB nuclear translocation. Alternative cancer therapy via autophagy is pros and cons since the autophagy in cancer cells is related to prevention and survival mechanism depending on nutrition. To avoid paradox of autophagy in cancer therapy, fine-tuned regulation and application of hinokitiol in due course for successful suppressing cancer cells are recommended.