• Journal of Technology Innovation
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• v.23 no.4
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• pp.205-244
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• 2015

In response to the recent rapid technological and market changes, the importance of the design of ambidextrous organization has been increasingly emphasized as one of the dynamic capabilities. Firms that show a high performance in the rapid technological and market changes appear to design and implement ambidextrous organization successfully. They have achieved both exploitative competence for continuous innovation with product development and exploratory competence for discontinuous innovation with new market and new technologies. We have examined why and how to design and operate ambidextrous organizations and the effects of ambidextrous organizational characteristics on the performance from structural, contextual and leadership perspectives. We conducted case studies on 3 Korean firms that showed different characteristics of industrial product, company size, etc. Longitudinal case studies exhibit different processes of design and operating ambidextrous organization according to innovative strategy and industrial characteristics.

• Information Systems Review
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• v.11 no.1
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• pp.145-160
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• 2009

Based on the user-centered innovation theory of von Hippel (2005), this research seeks to provide a case study of user innovation in the automobile navigation industry, which is a representative applied service in the area of Location-Based Service (LBS). The automobile navigation development and maintenance/repair processes of M&Soft are analyzed around the seven characteristics of user innovation as outlined by von Hippel. As a result, among the three strategic responses of sellers in the successful utilization of user innovation, it was determined that the approach of M&Soft was limited to providing an easy-to-use information technology platform so as to encourage members to easily share all types of map or mobile information or ideas. The significance of this paper is in that the theory of von Hippel originally based on physical products was applied to digital ones in line with the trend of increasing importance of Internet-based content services.

• Biomolecules & Therapeutics
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• v.24 no.1
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• pp.99-107
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• 2016

Triclosan is an antimicrobial or sanitizing agent used in personal care and household products such as toothpaste, soaps, mouthwashes and kitchen utensils. There are increasing evidence of the potentially harmful effects of triclosan in many systemic and cellular processes of the body. In this study, we investigated the effects of triclosan in the survivability of cultured rat neural stem cells (NSCs). Cortical cells from embryonic day 14 rat embryos were isolated and cultured in vitro. After stabilizing the culture, triclosan was introduced to the cells with concentrations ranging from $1{\mu}M$ to $50{\mu}M$ and in varied time periods. Thereafter, cell viability parameters were measured using MTT assay and PI staining. TCS decreased the cell viability of treated NSC in a concentration-dependent manner along with increased expressions of apoptotic markers, cleaved caspase-3 and Bax, while reduced expression of Bcl2. To explore the mechanisms underlying the effects of TCS in NSC, we measured the activation of MAPKs and intracellular ROS. TCS at $50{\mu}M$ induced the activations of both p38 and JNK, which may adversely affect cell survival. In contrast, the activities of ERK, Akt and PI3K, which are positively correlated with cell survival, were inhibited. Moreover, TCS at this concentration augmented the ROS generation in treated NSC and depleted the glutathione activity. Taken together, these results suggest that TCS can induce neurodegenerative effects in developing rat brains through mechanisms involving ROS activation and apoptosis initiation.

• Journal of Digital Convergence
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• v.16 no.1
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• pp.125-134
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• 2018

This study focused on the study of the moderating effects of absorptive capacity(AC) of venture firms on the technological innovation performance(TIP). For this purpose, this study analyzed the relationship between entrepreneurship(ENT), innovation competence(INC), external cooperation(EXO) and AC affecting the performance of technological innovation activities in venture companies in the area of Busan. As a result of analysis, the AC showed a role of moderating processes, in which ENT have affected the INC, and ENT, INC, and EXO have affected the TIP. Secondly, several relationships which have positively influenced or mediated, have been presented. ENT has positively influenced INC, EXO, & TIC. INC have done so EXC & TIP. EXC have done so TIP. Each of INC and EXC has been positively mediating the relationship between ENT & TIP.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.7
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• pp.165-174
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• 2016

This paper examined opportunities and limitations of building an innovation cluster based on large scale research facilities (LSRF). For this purpose, success factors of innovation clusters were drawn from the literature, and categorized into knowledge & technology, transaction cost & agglomeration economies, hardware & software infrastructure, and government policy & strategy. Utilizing the categorization as an analytic framework, case studies of CERN and SPring-8 were performed. The results showed that there were various innovation processes for both cases, creating opportunities for developing innovation clusters in terms of knowledge and technology. On the other hand, in the case of SPring-8, there were disadvantages in the transaction cost and agglomeration economies, being located in a remote area due to the nature of the facility. Software & hardware infrastructure of SPring-8 limited its potential for innovation clusters. Regarding government policy and strategy, CERN, as a multinational institution, did not consider an innovation cluster in a specific region despite some advantages. An innovation cluster around SPring-8 was promoted by government policy despite some disadvantages. In other words, the advantages and disadvantages were enhanced or complemented by software & hardware infrastructure and government policy & strategy. Based on the results, this paper provides the implications for the Korean International Science-Business Belt.

• Journal of the Economic Geographical Society of Korea
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• v.13 no.3
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• pp.335-353
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• 2010

Following the emergence of a knowledge-based economy, the triple helix model has been recognized as a new - regional and national - innovation model. This model seeks to understand the innovation process that is centered upon the university-industry-government interactions. The governance of the triple helix innovation system can be divided into three models according to the structure and depth of university-industry-government interactions. In the context of evolution, the triple helix can be established through the following three processes of development; i) internal transformation of each helix, ii) impacts of one helix on another helix, and iii) horizontal interactions among three helices. In theory, the triple helix model can be covered as part of the innovation system perspective. Compared to the innovation system perspective, the triple helix model tends to pay, however, more attention to the incompleteness of innovation system and the role of university in the process of knowledge creation. In view of regional innovation, the triple helix can be sustained when the triple helix spaces, including knowledge space, consensus space and innovation space, are created and the three triple helix spaces interact with one another. The existing literature on the triple helix model tends to make selectively use of only a single method between the qualitative method and the quantitative method, although both have shortcomings to reveal the dynamic characteristics of university-industry-government relations. Therefore, research on the triple helix is required to reconcile with two research methods, which are distinct but complementary in nature.

• Journal of Technology Innovation
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• v.28 no.4
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• pp.27-62
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• 2020

This study empirically verified the effect of environmental dynamism on changes in the dynamic and operational capabilities of an enterprise and its innovation performance. With the aim of quantification, the concept and definition of each capability were defined as a hierarchical structure of dynamic and operational capabilities. Five research hypotheses were established through prior research on dynamic capabilities, operational capabilities, innovation performance, and environmental dynamism. For empirical analysis, the hypotheses were verified based on surveys from 300 Korean manufacturing companies. It was shown that Dynamic capabilities had a positive relationship with operational capabilities and operational capabilities had a positive relationship with innovation performance. And it was shown that operational capabilities had a positive relationship with radical innovation in business groups with high environmental dynamism while operating capabilities had a positive relationship with gradual innovation in business groups with low environmental dynamism. Also, the moderating effect of environmental dynamism was not significant in the relationship with dynamic capabilities on operational capabilities. This study is meaningful in that it lays the groundwork for empirically verifying the dynamic capabilities of an enterprise by embodying its dynamic capabilities and operational capabilities into processes, and verifies the effect of environmental change on its capabilities and innovation performance. And it has implications to suggest how an enterprise should transform its capabilities to sustain its competitive advantage in a rapidly changing environment.

• International Journal of Quality Innovation
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• v.9 no.1
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• pp.1-21
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• 2008

A Purpose. As organizations become more team oriented, research on teams continues to increase especially involving how teams contribute to organizational performance and effectiveness. Although there has been existing research on Kaizen teams in the private sector, very little research has included Kaizen teams in the public sector. In this paper, we present a method to study Kaizen teams in a local Spanish government that have been using Kaizen teams for more than ten years. Design/methodology/approach. Quantitative research was adopted for this study. Twenty teams participated in the study by filling out the Team Learning and Development Inventory (TLI) proposed by Lingham (2004). In addition, we interviewed members of the teams in order to clarify and assure our quantitative results. Findings Based on the findings, we propose that Kaizen teams should practice both Continuous (CI) and Process Improvements (PI) in their projects. We also propose that Kaizen teams should not be teams skilled only at developing better improvement processes (both CI and PI) for the organization but that such teams should also be skilled at engaging in team development using both CI and PI processes internally-a Kaizen within Kaizen teams approach. Research limitations. Its based in one case study. However, it is working paper and the research project still is developing. Practical Implications (if possible). Serve as a guide to practitioners (Public managers) who desire to understand how their Kaizen teams involves both internal (conversational spaces) and external (methodology) perspectives that would contribute to both team and organizational effectiveness. In this paper, we focus on the Internal Processes (both CI and PI) using the TLI as an effective method for Kaizen teams to engage in the Kaizen process. Originality/value. This study is one of the first to look at team's performance using Team Learning and Development Inventory in Spain's public sector. It is also the first to mention about the relationship of the team's performance and the implementation of process improvement methodologies in Spain local government environment.

• Journal of electromagnetic engineering and science
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• v.1 no.1
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• pp.73-77
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• 2001

We studied the fabrication of GaAs-based pseudomorphic high electron mobility transistors(PHEMT`s) for the purpose of millimeter- wave applications. To fabricate the high performance GaAs-based PHEMT`s, we performed the simulation to analyze the designed epitaxial-structures. Each unit processes, such as 0.1 m$\mu$$\Gamma$-gate lithography, silicon nitride passivation and air-bridge process were developed to achieve high performance device characteristics. The DC characteristics of the PHEMT`s were measured at a 70 $\mu$m unit gate width of 2 gate fingers, and showed a good pinch-off property ($V_p$= -1.75 V) and a drain-source saturation current density ($I_{dss}$) of 450 mA/mm. Maximum extrinsic transconductance $(g_m)$ was 363.6 mS/mm at $V_{gs}$ = -0.7 V, $V_{ds}$ = 1.5 V, and $I_{ds}$ =0.5 $I_{dss}$. The RF measurements were performed in the frequency range of 1.0~50 GHz. For this measurement, the drain and gate voltage were 1.5 V and -0.7 V, respectively. At 50 GHz, 9.2 dB of maximum stable gain (MSG) and 3.2 dB of $S_{21}$ gain were obtained, respectively. A current gain cut-off frequency $(f_T)$ of 106 GHz and a maximum frequency of oscillation $(f_{max})$ of 160 GHz were achieved from the fabricated PHEMT\\`s of 0.1 m$\mu$ gate length.h.

• Journal of the Korean Society of Systems Engineering
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• v.2 no.1
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• pp.11-17
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• 2006

According to the change of customer needs, integration with other systems, and the advent of new technology, it is inevitable for the existing system requirements to be requested to redesign. However, there are actually no methodologies and processes to be able to reorganize the existing requirements or integrate a number of requirements different from each other. The traditional requirements processes do not work when solving such problems. Thus, since the existing approaches to develop requirements are not helpful, many traditional requirement engineering processes can not help falling in Red Ocean. In this paper, in order to solve such the problems, we propose a novel requirements engineering process applying Blue ocean strategy which is used to open a non-competition market not discovered yet. Blue Ocean approach is a novel effective method to elicit and build up new requirements from customers. In order to accomplish the strategy, this paper presents a framework and processes to discover new perspectives and analyze the corresponding requirements. In addition, some pieces of case study are presented to introduce how our approach is applied to practical system developments and the evaluation analysis for how valid it is.