• 한국전자통신학회논문지
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• 제2권1호
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• pp.19-24
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• 2007

Abstract. In the ubiquitous environment of the next generation, RFID is predicted to occupy an important technical location and also expected to apply to various fields. However, the properties of tags in itself which is the core of RFID have a dysfunction like an invasion of privacy for user. An existing cryptanalytic protection scheme of the information leakage have a difficult problem to apply to RFID tags for privacy protection. We applied Ohkubo et al.'s scheme to the protection of the tag's information efficiently in the RFID system environment using low-cost tags. But, this method has all informations of tagsto identify tag's ID and then performs the process of identification in sequence in the Back-end server. These processes have lots of computations so that it have problems about a scalability. In this paper, we are based on Ohkubo et al.'s scheme to solve problems, and then analyze the parallelism with the Hellman's tradeoff method, divide it into nodesin parallel. In this paper, we are based on Okubo et al.'s scheme to solve problems, and then analyze the parallelism with Hellman's tradeoff method, divide it into the ${\omega}$ node in parallel. as a result, we can reduce the computing complexity of key search to $O(\frac{m^{2/3}n^{2/3}}{\omega})$ seconds from O(mm) seconds. finally we show the results to be enhanced the scalability.

• 한국항행학회논문지
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• 제18권5호
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• pp.518-523
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• 2014

현대사회는 사회, 과학기술의 발달로 원자력, 정보화 등 신기술에 기인하는 역기능의 위험성이 증가하고, 재난 또한 과거에 없었던 새로운 위험들이 증가하면서 복합적인 재난으로 변화하였다. 이와 함께 도시화와 인구밀집은 고층건물화재, 교통사고, 범죄등의 위험도를 증가시키고 있다. 이렇게 다양한 위험요소로부터 예방 대비 대응하기 위하여 사회안전무선통신망의 구축은 절대적으로 필요하다. 사회안전무선통신망의 구축, 유지 및 관리가 항상 이루어져야하며 긴급한 상황에서도 통신망이 유지되도록 힘써야 한다. 본 논문에서는 복합재난으로부터 예방 및 대비, 대응하기 위한 사회안전무선통신망을 알아보고, 사회안전무선통신망을 분석하여 망 구현을 위한 필수기능, 부가기능 등의 요구사항을 연구하였다.

• 한국도서관정보학회지
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• 제49권3호
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• pp.33-53
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• 2018

많은 공공도서관은 다양한 이유를 근거로 음식물 반입을 제한(또는 금지)하고 있는데, 그것이 정당한지 아니면 부당한지를 논증할 필요가 있다. 이에 본 연구는 공공도서관을 이용하는 대구시민 485명을 대상으로 음식물 정책에 대한 인식을 조사하고 그 결과를 바탕으로 다양한 관점에서 개선방향을 제시하였다. 첫째, 사회 사조 측면에서 음식물 제한정책에 대한 전향적인 재검토가 필요하다. 둘째, 이용자 기본권 보장 차원에서는 이용자의 음식물 반입을 허용하는 것이 공공도서관의 존재가치와 사회적 역할을 정당화하고 생태계를 강화하는데 유리하다. 셋째, 장서 및 시설공간의 이용촉진 측면에서 음식물 허용에 따른 역기능보다 순기능을 강조하는 것이 바람직하다. 넷째, 자치조례나 도서관 규정에 모든 또는 대다수 음식물을 제한하는 전체주의적 사고는 지양되어야 한다. 마지막으로 공공도서관은 음식물 반입을 허용하되, 공간별로 섭취 가능한 종류를 규정하고 이용자에게 적극적으로 홍보할 필요가 있다.

• Reproductive and Developmental Biology
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• 제33권2호
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• pp.93-98
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• 2009

In this study, bovine Dnmt1 cDNA was sequenced and detected Dnmt1 mRNA level in bovine tissues by northern blot, methylation pattern of genome by southern blot, specific localization of Dnmt1 in mouse and bovine preimplantation embryos by immunocytostaining and Dnmt1 protein level in ovary and testis by western blot. Bovine Dnmt1 cDNA sequence showed more homology with that of human than mouse and rat. The RNA level of Dnmt1 was 10 times higher expression in placenta than other tissues. This indicates that placenta was hypermethylated compared to others organs. The genomic DNA could not be cut by a specific restriction enzyme (HpaII) in placenta, lung and liver of bovine. It suggests that Dnmt1 in some somatic cells was already methylated. Dnmt1, which has the antibody epitope 1316~1616, was distributed in nucleus and cytoplasm including the stage of pronuclear stage and maturation of oocyte and gradually weaken to blastocyst stage compare to negative. In addition, Dnmt1 was strongly expressed in tetraploid embryo and cloned 8-cell than IVF 8-cell. An aberrant pattern of DNA methylation in cloned embryo may be abnormal development of fetus, embryonic lethality and placenta dysfunction. The somatic specific band (190kDa) was appeared in ovary and testis, but oocyte specific band (175kDa) was not. Further investigations are necessary to understand the complex links between the methyltransferases and the transcriptional activity of genes in the cloned bovine tissues.

• 한국정보통신학회논문지
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• 제16권8호
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• pp.1765-1772
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• 2012

의료기기 및 진단 기술의 발달로 신체 장기의 이식에 대한 성공률이 향상되었으며 특히 간 기능 장애에 의한 간이식이 늘어나는 추세이다. 영상처리 및 분석의 발달로 간 이식을 위한 간의 체적을 구하는 방법들이 정확성과 효율성이 높아졌다. 본 논문은 각 알고리즘들의 신속한 비교 및 분석, 빠른 프로토타입 개발에 효과적인 MeVisLab을 사용하여 간 영역을 분할하고 재구성하였다. 원본 영상에 문턱치 값 적용과 영역 확장법을 적용하여 간 영역을 분할하고 Morphology와 구멍 채우기, 관심영역 설정으로 노이즈 및 불필요한 객체를 제거하여 간을 분할하였다. MeVisLab의 사용으로 높은 시간적 효율과 다양한 비교 및 분석 모듈 사용 방법을 제시하여 의료영상처리 연구의 저변 확대에 기여하리라 판단된다.

• 대한한방내과학회지
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• 제43권4호
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• pp.720-737
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• 2022

Objectives: To compare the effectiveness and safety of East Asian traditional medicine treatments (EATMT) versus conventional management in patients following heart valve replacement surgery. Methods: We searched several databases, including the Korean Studies Information Service System, PubMed, China National Knowledge Infrastructure, and Citation Information by NII. The search range included randomized controlled trials from each first issue until June 27, 2021. Two review authors independently extracted the data. We assessed the risk of systematic errors by evaluating risk domains using the "Risk of bias" tool. Results: We included 5 trials in the review. In the EATMT, the investigators reported significant improvements in reshaping of the heart structure: left ventricular end diastolic diameter (MD -4.43, 95% CI -6.06 to -2.79; 130 participants; 2 studies; high evidence). Comparisons with usual care revealed a significant decrease in gastrointestinal complications rate (OR 0.30, 95% CI 0.20 to 0.47; 503 participants; 2 studies; high evidence). We assessed 4 studies as having a low risk of bias and 1 study as having a high risk of bias. Conclusion: This systematic review suggests that East Asian traditional medicine interventions may be effective in preventing and alleviating complications, but we found evidence of important trade-offs between known benefits and known adverse effects in cardiac dysfunction and inflammation following heart valve replacement. Consequently, additional high-quality studies should be conducted.

• Journal of Cerebrovascular and Endovascular Neurosurgery
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• 제25권3호
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• pp.275-287
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• 2023

Objective: Flow diverting stents (FDS) are a validated device in the treatment of intracranial aneurysms, allowing for minimally invasive intervention. However, after its approval for use in the United States in 2011, post-market surveillance of adverse events is limited. This study aims to address this critical knowledge gap by analyzing the FDA Manufacturer and User Facility Device Experience (MAUDE) database for patient and device related (PR and DR) reports of adverse events and malfunctions. Methods: Using post-market surveillance data from the MAUDE database, PR and DR reports from January 2012-December 2021 were extracted, compiled, and analyzed with R-Studio version 2021.09.2. PR and DR reports with insufficient information were excluded. Raw information was organized, and further author generated classifications were created for both PR and DR reports. Results: A total of 2203 PR and 4017 DR events were recorded. The most frequently reported PR adverse event categories were cerebrovascular (60%), death (11%), and neurological (8%). The most frequent PR adverse event reports were death (11%), thrombosis/thrombus (9%) cerebral infarction (8%), decreased therapeutic response (7%), stroke/cerebrovascular accident (6%), intracranial hemorrhage (5%), aneurysm (4%), occlusion (4%), headache (4%), neurological deficit/dysfunction (3%). The most frequent DR reports were activation/positioning/separation problems (52%), break (9%), device operates differently than expected (4%), difficult to open or close (4%), material deformation (3%), migration or expulsion of device (3%), detachment of device or device component (2%). Conclusions: Post-market surveillance is important to guide patient counselling and identify adverse events and device problems that were not identified in initial trials. We present frequent reports of several types of cerebrovascular and neurological adverse events as well as the most common device shortcomings that should be explored by manufacturers and future studies. Although inherent limitations to the MAUDE database are present, our results highlight important PR and DR complications that can help optimize patient counseling and device development.

• Tuberculosis and Respiratory Diseases
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• 제73권4호
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• pp.231-233
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• 2012

Tadalafil is a phosphodiesterase-5 inhibitor (PDE5I), which is widely used to treat erectile dysfunction. Although PDE5Is have excellent safety profiles, and most of the side effects are mild, rare serious adverse events have been reported in association with PDE5Is. Thrombosis is one of those events, and a few previous reports have suggested the association of PDE5Is with thrombosis. We report the case of a 61-year-old male who developed pulmonary embolism combined with pulmonary infarction directly after taking tadalafil. Both the patient and the physician suspected tadalafil as the culprit drug, as the patient was in an otherwise healthy condition. However, after extensive evaluation, we noticed that factor VIII levels were elevated. Prior reports suggesting the association between thrombosis and PDEIs either lack complete information on coagulation factors, or show inconsistencies in their results. Physicians should operate caution prior to accepting the diagnosis of adverse drug reaction.

• Clinical and Experimental Pediatrics
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• 제63권3호
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• pp.79-87
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• 2020

Inherited platelet disorders (IPDs), which manifest as primary hemostasis defects, often underlie abnormal bleeding and a family history of thrombocytopenia, bone marrow failure, hematologic malignancies, undefined mucocutaneous bleeding disorder, or congenital bony defects. Wide heterogeneity in IPD types with regard to the presence or absence of thrombocytopenia, platelet dysfunction, bone marrow failure, and dysmegakaryopoiesis is observed in patients. The individual processes involved in platelet production and hemostasis are genetically controlled; to date, mutations of more than 50 genes involved in various platelet biogenesis steps have been implicated in IPDs. Representative IPDs resulting from defects in specific pathways, such as thrombopoietin/MPL signaling; transcriptional regulation; granule formation, trafficking, and secretion; proplatelet formation; cytoskeleton regulation; and transmembrane glycoprotein signaling are reviewed, and the underlying gene mutations are discussed based on the National Center for Biotechnology Information database and Online Mendelian Inheritance in Man accession number. Further, the status and prevalence of genetically confirmed IPDs in Korea are explored based on searches of the PubMed and KoreaMed databases. IPDs are congenital bleeding disorders that can be dangerous due to unexpected bleeding and require genetic counseling for family members and descendants. Therefore, the pediatrician should be suspicious and aware of IPDs and perform the appropriate tests if the patient has unexpected bleeding. However, all IPDs are extremely rare; thus, the domestic incidences of IPDs are unclear and their diagnosis is difficult. Diagnostic confirmation or differential diagnoses of IPDs are challenging, time-consuming, and expensive, and patients are frequently misdiagnosed. Comprehensive molecular characterization and classification of these disorders should enable accurate and precise diagnosis and facilitate improved patient management.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제30권6호
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• pp.482-487
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• 2004

Aims: This study was designed to determine the incidence of altered sensation in patients undergoing orthognathic surgery. Method: Seventy two patients who underwent orthognathic surgery between January, 1999 and December, 1999 constituted the study group. Seven patients were excluded because of lack of follow up. Sixty five patients were followed using objective and subjective neurologic testing during the period immediately following operation, 1 month, 2 months, 6 months, and 1 year postoperatively. Age ranged from 17 to 38 years, with a mean of 24.5 years. Male patients were 21, female 44. Twenty eight bilateral sagittal splitting ramus osteotomy(BSSRO) of mandible were performed, 35 BSSRO with genioplasty, 2 genioplasties. Information on the degree of intraoperative nerve encounter was obtained from the surgical reports in 47 patients and was divided into the following three categories: (1) the nerve was not encountered in 23 patients; (2) the nerve was exposed in 11 patients; (3) the nerve was exposed and repositioned from the proximal segment in 13 patients. Results: Four patients reported altered nerve sensation of lower lip and/or chin(6.2%) at final follow up. Two patients underwent BSSRO and the other two patients BSSRO with genioplasty. Three of the patients underwent nerve exposure during the operation. Conclusion: We suggest that the nerve exposure during the operation might be partly responsible for nerve dysfunction after orthognathic surgery.