• 제목/요약/키워드: Human structure and function

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디지털 환경의 웰빙 패션 디자인에 관한 연구 (A Study on Characteristics of Well-being Fashion Design in Digital Environment)

  • 김지언
    • 복식문화연구
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    • 제15권5호
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    • pp.796-809
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    • 2007
  • The viewpoint of growth pursuit is changed to that of life quality's and happiness' pursuit by modern people. Modern people in digital environment, tired of fast-changing and oppressive daily life, prefer well-being trend providing tranquility and relaxation. Well-being is related to digital, because negative influences of digital lead human-oriented, environment-friendly well-being design. Therefore the purpose of this study is to research and analyze the relation of well-being fashion design and digital environment through case study in contemporary well-being fashion design. The results of this study are as follows: 1. This study shows that the attributes of digital environment make up function-intensive, interactivity, mobility & nomad, human & emotion-oriented and environment-friendly. And this study shows the design characteristics of digital environment consist of function-intensive design by digital convergence, open structure design for interactivity, modular design for mobility & nomad, emotion-oriented & multi-sensory design and environment- friendly design. 2. Function-intensive design in modem well-being fashion composed of vogue of caports style(casual+sports), practical use of multi-functional new-healthy textiles, and popularity of many style's mixture at once. Open structure design consist of wrapover design, use of transparent materials. Modular design are layered styling, practical use of zipper and velcro. Emotion-oriented & multi-sensory design are constitute of fad of wrinkle materials, application of bright & vivid tone, personal color and family look. Environment-friendly design in contemporary well-being fashion are comprised in use of natural color, re-advent of natural floral motif and eco-design.

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Characterization and function of human Ly-6/uPAR molecules

  • Kong, Hyun Kyung;Park, Jong Hoon
    • BMB Reports
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    • 제45권11호
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    • pp.595-603
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    • 2012
  • Human Ly-6/uPAR molecules are a superfamily composed of two subfamilies; one is the membrane bound proteins with a GPI-anchor and the other are secreted proteins without the GPI-anchor. Ly-6/uPAR molecules have remarkable amino acid homology through a distinctive 8-10 cysteine-rich domain that is associated predominantly with O-linked glycans. These molecules are encoded by multiple tightly linked genes located on Chr. 8q23, and have a conserved genomic organization. Ly-6/uPAR molecules have an interesting expression pattern during hematopoiesis and on specific tumors indicating that Ly-6/uPAR molecules are associated with development of the immune system and carcinogenesis. Thus, Ly-6/uPAR molecules are useful antigens for diagnostic and therapeutic targets. This review summarizes our understanding of human Ly-6/uPAR molecules with regard to molecular structure as well as what is known about their function in normal and malignant tissues and suggest Ly-6/uPAR molecules as target antigens for cancer immunotherapy.

추상화계층에 기반한 작업영역분석의 모델링 개념 및 적용 원칙 (Work Domain Analysis Based on Abstraction Hierarchy: Modelling Concept and Principles for Its Application)

  • 함동한
    • 대한안전경영과학회지
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    • 제15권3호
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    • pp.133-141
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    • 2013
  • As a work analysis technique, Work Domain Analysis (WDA) aims to identify the design knowledge structure of a work domain that human operators interact with through human-system interfaces. Abstraction hierarchy (AH) is a multi-level, hierarchical knowledge representation framework for modeling the functional structure of any kinds of systems. Thus, WDA based on AH aims to identify the functional knowledge structure of a work domain. AH has been used in a range of work domains and problems to model their functional knowledge structure and has proven its generality and usefulness. However, many of researchers and system designers have reported that it is never easy to understand the concepts underlying AH and use it effectively for WDA. This would be because WDA is a form of work analysis that is different from other types of work analysis techniques such as task analysis and AH has several unique characteristics that are differentiated from other types of function analysis techniques used in systems engineering. With this issue in mind, this paper introduces the concepts of WDA based on AH and offers a comprehensive list of references. Next, this paper proposes a set of principles for effectively applying AH for work domain analysis, which are developed based on the author's experiences, consultation with experts, and literature reviews.

신형경수로 1400을 위한 신뢰성 평가 (Reliability Evaluation for the Advanced Pressurized water Reactor 1400)

  • 강영식
    • 한국안전학회지
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    • 제16권3호
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    • pp.125-134
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    • 2001
  • The Advanced Pressurized rater Reactor 1400(APR1400) system is advanced of the successful Korean Nuclear Power Plants(KSNP) design which meets functional needs for safety enhancement reliability improvement, and control in the human-computer monitoring system. Therefore this paper describes the scoring model in order to justify the reliability and safety in APR 1400 under uncertainty. The structure of this paper consists of the human engineering, risk safety, quality function, safety organization management factors of the qualitative factors in chapter 2, and the expectation results of the normalized scoring model in chapter 3. Finally, the proposed reliability model have provided the technical flexibility not only for functional control fields but also for accidents protection systems in APR 1400 under uncertainty.

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The primary cilium as a multiple cellular signaling scaffold in development and disease

  • Ko, Hyuk-Wan
    • BMB Reports
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    • 제45권8호
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    • pp.427-432
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    • 2012
  • Primary cilia, single hair-like appendage on the surface of the most mammalian cells, were once considered to be vestigial cellular organelles for a past century because of their tiny structure and unknown function. Although they lack ancestral motility function of cilia or flagella, they share common ground with multiciliated motile cilia and flagella on internal structure such as microtubule based nine outer doublets nucleated from the base of mother centrioles called basal body. Making cilia, ciliogenesis, in cells depends on the cell cycle stage due to reuse of centrioles for cell division forming mitotic spindle pole (M phase) and assembling cilia from basal body (starting G1 phase and maintaining most of interphase). Ciliary assembly required two conflicting processes such as assembly and disassembly and balance between these two processes determines the length of cilia. Both process required highly conserved transport system to supply needed substance to grow tip of cilia and bring ciliary turnover product back to the base of cilia using motor protein, kinesin and dynein, and transport protein complex, IFT particles. Disruption of ciliary structure or function causes multiple human disorder called ciliopathies affecting disease of diverse ciliated tissues ranging from eye, kidney, respiratory tract and brain. Recent explosion of research on the primary cilia and their involvement on animal development and disease attracts scientific interest on how extensively the function of cilia related to specific cell physiology and signaling pathway. In this review, I introduce general features of primary cilia and recent progress in understanding of the ciliary length control and signaling pathways transduced through primary cilia in vertebrates.

Human Sensibility Ergonomics Investigation of Car Navigation System Digital Map Color Structure

  • Cha, Doo-Won;Park, Peom
    • 산업경영시스템학회지
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    • 제23권60호
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    • pp.47-55
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    • 2000
  • Two experiments were conducted to examine the relationships between the color structure and the user preference of a CNS (Car Navigation System) digital map in terms of HSE (Human Sensibility Ergonomics). In the first experiment, the user's preference of color structures were investigated from the subjects' self-designed digital maps using a CNS digital map UIMS (User Interface Management System): in the second, statistical relation models between the user's color structure satisfaction level and the color components of CIE (Commission Internationale de ι'Eclairage) of the real products were suggested. For each experiment, CIE L*u*v* and CIE LCH color space were adapted, respectively, because they have their own characteristics of perceptual uniformity which enables the color components to transform a linear function.

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우리나라 온천의 실태와 치료적 효과에 관한 연구 (The studies of actual condition and therapeutic effects of hot spring water in Korea)

  • 박래준
    • The Journal of Korean Physical Therapy
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    • 제12권3호
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    • pp.369-377
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    • 2000
  • Hot spring water is petrifaction water and mixed with animals and plants disintegrated water in the underground. The ingredient are complicated and abundant. The contained element is used to facilitate the function of human body. activate the human structure movement. discharge waste material due to increase circulation and metabolism, also it can remain the homeostasis. We can not find research for spa therapy in our country. We use to drink and bath in the hot spring water bue don't have rehabilitation facilities

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서버리스 플랫폼에서 GPU 지원 및 인공지능 모델 추론 에 적합한 함수 구조에 관한 연구 (A Study on Function which supported GPU and Function Structure Optimization for AI Inference)

  • 황동현;김동민;최영윤;한승호;전기만;손재기
    • 한국정보처리학회:학술대회논문집
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    • 한국정보처리학회 2019년도 추계학술발표대회
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    • pp.19-20
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    • 2019
  • 서버리스 프레임워크(Serverless Framework)는 마이크로서비스 아키텍처의 이론을 클라우드와 컨테이너를 기반으로 구현한 것으로 아마존의 AWS(Amazon Web Service)와 같은 퍼블릭 클라우드 플랫폼이 서비스됨에 따라 활용도 높아지고 있다. 하지만 현재까지의 플랫폼들은 GPU 와 같은 하드웨어의 의존성을 가진 인공지능 모델의 서비스에는 지원이 부족하다. 이에 본 논문에서는 컨테이너 기반의 오픈소스 서버리스 플랫폼을 대상으로 엔비디어-도커와 k8s-device-plugin 을 적용하여 GPU 활용이 가능한 서버리스 플랫폼을 구현하였다. 또한 인공지능 모델이 컨테이너에서 구동될 때 반복되는 가중치 로드를 줄이기 위한 구조를 제안한다. 본 논문에서 구현된 서버리스 플랫폼은 객체 검출 모델인 SSD(Single Shot Multibox Detector) 모델을 이용하여 성능 비교 실험을 진행하였으며, 그 결과 인공지능 모델이 적용된 서버리스 플랫폼의 함수 응답 시간이 개선되었음을 확인하였다.

심리적 공간구조의 연장적 결합원리 연구 - 화이트헤드의 연장이론을 중심으로 - (A Study on the Principles of Extensive Connection in Psychological and Spatial Structure - Focused on the Extension Theory of Alfred North Whitehead -)

  • 박경아
    • 한국실내디자인학회논문집
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    • 제20권6호
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    • pp.79-87
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    • 2011
  • Spatial perception and spatial structure that focus on psychological effects produce a real force through the medium of space that can control human actions, even their psychology. The job of understanding the characteristics and effects of architectural spaces that recognize the relationship between architecture and human beings, including the psychological dimension, is an alternative search for quality spaces that can increase the mutual relationship between space and human beings. This paper introduces two propositions called "space" and "psychology" in order to discover a meta-pattern connecting space and the human mind with the aim of systematizing that internal network and establishing a new architectural system concerning space and human beings. This paper also proposes a method of accessing physical spaces that can affect psychological states through a conceptual substitution called "extension," with the aim of discovering the implications inherent in such extensive relationships and proposing a methodology of organizing psychological spaces based on the characteristics of that extensive connection. The means of extensively connecting psychological spaces were classified into the three categories of memory system, sensory system, and motor system, and their corresponding extensive connection characteristics called "simultaneous relativity," "non-mediated immediacy," and "purification process" were also derived. These characteristics accelerate the changes in psychological intensity and function as principles that organize psychological space.

Comparative Genomics of T-complex protein 10 like in Humans and Chimpanzees

  • Kim, Il-Chul;Kim, Dae-Soo;Kim, Dae-Won;Choi, Sang-Haeng;Choi, Han-Ho;Chae, Sung-Hwa;Park, Hong-Seog
    • Genomics & Informatics
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    • 제3권2호
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    • pp.61-65
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    • 2005
  • Comparing 231 genes on chimpanzee chromosome 22 with their orthologous on human chromosome 21, we have found that 15 orthologs have indels within their coding sequences. It was rather surprising that significant number of genes have changed by indel, despite the shorter time since their divergence and led us hypothesize that indels and structural changes may represent one of the major mechanism of proteome evolution in the higher primates. Human T-complex protein 10 like (TCP 10L) is a representative having indel within its coding sequence. Gene structure of human TCP10L compared with chimpanzee TCP10L gene showed 16 base pair difference in genomic DNA. As a result of the indel, frame shift mutation occurs in coding sequence (CDS) and human TCP10L express longer polypeptide of 21 amino acid residues than that of chimpanzee. Our prediction found that the indel may affect to dramatic change of secondary protein structure between human and chimpanzee TCP10L. Especially, the structural changes in the C-terminal region of TCP10L protein may affect on the interacting potential to other proteins rather than DNA binding function of the protein. Through these changes, TCP10L might influence gene expression profiles in liver and testis and subsequently influence the physiological changes required in primate evolution.