• Journal of KIISE:Databases
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• v.31 no.3
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• pp.232-242
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• 2004

Metadata is a general notion of data about data to improve data sharing and exchanging by definitely describing meaning and representation of data. However, metadata has been created in various ways and It caused another kind of heterogeneity problem named metadata heterogeneity problem. Recently, the research on metadata gateway approach that allows metadata heterogeneity is being more actively progressed. However, the existing commercialized systems that have been implemented with the metadata gateway approach are dependent on a metadata schema. In this paper, we propose a message conversion system which separates the mapping information from the mapping rules between heterogeneous metadata schemas. The proposed system dynamically manages standardized data elements by applying ISO/IEC l1179. Therefore, the proposed system provides the set of standard data elements to create consistently metadata of new databases and provides a fundamental resolution to the metadata heterogeneity problem.

• Anatomy and Cell Biology
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• v.56 no.1
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• pp.94-108
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• 2023

Cancer cell heterogeneity is a serious problem in the control of tumor progression because it can cause chemoresistance and metastasis. Heterogeneity can be generated by various mechanisms, including genetic evolution of cancer cells, cancer stem cells (CSCs), and niche heterogeneity. Because the genetic heterogeneity of CSCs has been poorly characterized, the genetic mutation status of CSCs was examined using Exome-Seq and RNA-Seq data of liver cancer. Here we show that different surface markers for liver cancer stem cells (LCSCs) showed a unique propensity for genetic mutations. Cluster of differentiation 133 (CD133)-positive cells showed frequent mutations in the IRF2, BAP1, and ERBB3 genes. However, leucine-rich repeat-containing G protein-coupled receptor 5-positive cells showed frequent mutations in the CTNNB1, RELN, and ROBO1 genes. In addition, some genetic mutations were frequently observed irrespective of the surface markers for LCSCs. BAP1 mutations was frequently observed in CD133-, CD24-, CD13-, CD90-, epithelial cell adhesion molecule-, or keratin 19-positive LCSCs. ASXL2, ERBB3, IRF2, TLX3, CPS1, and NFATC2 mutations were observed in more than three types of LCSCs, suggesting that common mechanisms for the development of these LCSCs. The present study provides genetic heterogeneity depending on the surface markers for LCSCs. The genetic heterogeneity of LCSCs should be considered in the development of LCSC-targeting therapeutics.

• Asia-Pacific Journal of Business
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• v.12 no.2
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• pp.39-60
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• 2021

Purpose - The purpose of this paper is exploring whether the characteristics and heterogeneity of the TMT play a moderating role in CSR and corporate value or not. Design/methodology/approach - The literature research method includes collecting, organizing, and analyzing the literature on the characteristics and heterogeneity of the TMT, the effect of corporate social responsibility (CSR), and corporate value. We analyze the contributions and limitations in existing research, grasp the current research status, and develop the research content of this article. The empirical analysis method is based on the data of Chinese A-share listed companies from 2001 to 2017. This allows us to study the moderating effect of the characteristics and heterogeneity of the TMT on CSR and corporate value. Findings - The TMT age, education degree, overseas background, and compensation have a positive moderating effect on CSR and corporate market value. The comprehensive heterogeneity of the TMT also has a positive effect on CSR and financial performance. Research implications or Originality - The research on the relationship between CSR and corporate value is still inconclusive. Some results have found a positive relationship, while others show a negative relationship. Studies exist that report mixed findings as well. This study has attempted to clarify this problem by adding potentially missing variables related on the TMT characteristics and heterogeneity, investigating causality effects.

• Proceedings of the Korean Information Science Society Conference
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• 2011.06c
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• pp.96-97
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• 2011

Heterogeneity in different Health Information Systems (HIS) processes persists to be the most demanded problem to be resolved in healthcare domain. The only way to resolve this problem is to practice health standards. One of such standards is Health Level Seven (HL7), used for the communication of medical information between healthcare systems. HL7 V3 has the aim to support all healthcare workflows. It defines series of electronic messages called interactions to support healthcare workflows. These interactions are part of the Interaction Model. Different healthcare organizations can conform to different process workflows based on their requirements. The heterogeneity in workflows results in communication blockade between sender and receiver healthcare organizations. We propose Interaction Ontology in order to cater the heterogeneity in workflows and provide process interoperability.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.25 no.1
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• pp.69-75
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• 2007

The information in physical planning field shows the socio-economic potentials of land resources while cadastral data does the physical and legal realities of the land. The two domains commonly deal with land information but have different views. Cadastre has to evolved to the multi-purpose ones which provide value-added information and support a wide spectrum of decision makers by mixing their own information with other spatial/non-spatial databases. In this context, the demands of data exchange between the two domains is growing up but this cannot be done without resolving the heterogeneity between the two information applications. Both of either discipline sees the reality within its own scope, which means each has a unique way to abstract real world phenomena to the database. The heterogeneity problem emerges when an GIS is autonomously and independently established. It causes considerable communication difficulties since heterogeneity of representations forms unique data semantics for each database. The semantic heterogeneity obviously creates an obstacle to data exchange but, at the same time, it can be a key to solve the problems too. Therefore, the study focuses on facilitating data sharing between the fields of cadastre and physical planning by resolving the semantic heterogeneity. The core job is developing a conversion mechanism of cadastral data into the information for the physical planning by DB coupling techniques.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.17 no.3
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• pp.958-979
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• 2023

Due to laws, regulations, privacy, etc., between 70-90 percent of providers do not share medical data, forming a "data island". It is essential to collaborate across multiple institutions without sharing patient data. Most existing methods adopt distributed learning and centralized federal architecture to solve this problem, but there are problems of resource heterogeneity and data heterogeneity in the practical application process. This paper proposes a collaborative deep learning modelling method based on the blockchain network. The training process uses encryption parameters to replace the original remote source data transmission to protect privacy. Hyperledger Fabric blockchain is adopted to realize that the parties are not restricted by the third-party authoritative verification end. To a certain extent, the distrust and single point of failure caused by the centralized system are avoided. The aggregation algorithm uses the FedProx algorithm to solve the problem of device heterogeneity and data heterogeneity. The experiments show that the maximum improvement of segmentation accuracy in the collaborative training mode proposed in this paper is 11.179% compared to local training. In the sequential training mode, the average accuracy improvement is greater than 7%. In the parallel training mode, the average accuracy improvement is greater than 8%. The experimental results show that the model proposed in this paper can solve the current problem of centralized modelling of multicenter data. In particular, it provides ideas to solve privacy protection and break "data silos", and protects all data.

• Journal of the Korean Operations Research and Management Science Society
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• v.40 no.4
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• pp.145-156
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• 2015

Incorporation of individual learning and forgetting behaviors within worker-task assignment models produces a mixed integer nonlinear program (MINLP) problem, which is difficult to solve as a NP hard due to its nonlinearity in the objective function. Previous studies commonly assume homogeneity among workers in workforce scheduling that takes account of learning and forgetting characteristics. This paper expands previous researches by considering heterogeneous individual learning/forgetting, and investigates the impact of worker heterogeneity in initial expertise, steady-state productivity, learning and forgetting on system performance to assist manager's decision-making in worker-task assignments without tackling complex MINLP models. In order to understand the performance implications of workforce heterogeneity, this paper examines analytically how heterogeneity in each of the four parameters of the exponential learning and forgetting (L/F) model affects system performance in three cases : consecutive assignments with no break, n breaks of s-length each, and total b break-periods occurred over T periods. The study presents the direction of change in worker performance under different assignment schedules as the variance in initial expertise, steady-state productivity, learning or forgetting increases. Thus, it implies whether having more heterogenous workforce in terms of each of four parameters in the L/F model is desired or not in different schedules from the perspective of system productivity measurement.

• The KIPS Transactions:PartA
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• v.12A no.1 s.91
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• pp.31-40
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• 2005

In this paper, we propose XMDR(XML Metadata Registry) to guarantee the interoperability of data in distributed database, and describe a data synchronizing agent system using it. The proposal of XMDR is to solve the data heterogeneity problem in the sharing and exchanging data. Data heterogeneity problem is generated by different definition or mismatching expression of the same information. Therefore, we define XMDR with XML document by analyzing data elements based on MDR specification. The proposed synchronizing agent system using XMDR not only solves data heterogeneity for data interoperability in synchronizing data but also provides more efficient the agent system by offering errors of low frequency in the number of systems and requests of synchronizing data.

• The Journal of the Korea institute of electronic communication sciences
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• v.17 no.5
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• pp.801-808
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• 2022

Research on how to embed knowledge in large-scale Linked Data and apply neural network models for entity matching is relatively scarce. The most fundamental problem with this is that different labels lead to lexical heterogeneity. In this paper, we propose an extended GCN (Graph Convolutional Network) model that combines re-align structure to solve this lexical heterogeneity problem. The proposed model improved the performance by 53% and 40%, respectively, compared to the existing embedded-based MTransE and BootEA models, and improved the performance by 5.1% compared to the GCN-based RDGCN model.

• Journal of Engineering Education Research
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• v.18 no.4
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• pp.26-33
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• 2015

The purpose of this study is to microscopically analyze the problem solving activities in creative robotics making and programming activity in order to investigate the characteristics of team interaction in accordance with MBTI disposition of team members in the creative robotics making activity in which the engineering education has a lot interest in the recent years. For the prosecution of this study, teams composed of 2 students targeting 30 students who were at the related department of engineering education in the college of eduction, A university located in Daejeon were organized. In addition, individual propensities of team members, in other words, team dynamic structure and team interaction were analyzed through microscopical analysis of the problem solving activities in creative robotics making and programming activity. The results of this study showed that there was a static correlation between the organization of MBTI Heterogeneity team and the interaction of team members, and also there was a positive interaction of team members in organizing MBTI Homogeneity team in area of Thought (T) - Feeling (F). In addition, mutual complement to solve the problems was carried out and the problem-solving capability was shown in the course of the communication along with the organization of MBTI team of extreme heterogeneity.