• 대한한의학원전학회지
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• 제21권1호
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• pp.143-151
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• 2008

Objective : Classification of herbal formulas through the analysis of compositional herb's is a suitable method in the aspects of the effective applications of herbal formulas. However, these classification methods have some problems in dealing with lots of herbal formulas because the estimations of herbal formula's effects are dependent upon one's memory. In this study, we aimed to establish the effective methodology to elicit the classified herbal formula's chart by introducing the DB systems without interfering with non-standard terms. Results : We have known that this plan is realized by follow methods. We entered the herbs informations of the composition of herbal formulas into database, made an alias tables of corresponding herbs, and achieved standardization of herb's informations. Using these databases, we made the classified herbal formula's chart according to the presence and the treatment informations of herbs.

• 대한한의학원전학회지
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• 제21권1호
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• pp.123-141
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• 2008

Objective Classification of herbal formulas through the analysis of compositional herb's is a suitable method in the aspects of the effective applications of herbal formulas. However, these classification methods have some problems in dealing with lots of herbal formulas because the estimations of herbal formula's effects are dependent upon one's memory. In this study, we aimed to establish the effective methodology to elicit the classified herbal formula's chart by introducing the DB systems without interfering with non-standard terms. Method : We entered the herbs informations of the composition of herbal formulas into database, made an alias tables of corresponding herbs, and achieved standardization of herb's informations. Using these databases, we made the classified herbal formula's chart according to the presence and the treatment informations of herbs. Results By analyzing the herbal formula into the set of compositional herbal elements, we could systemically express the parents and children herbal formula at once according to search terms. We provided the advanced searching tools entering the name of herbal formula and compositional herb together. Through these searching methods, it is facilitated to grasp the classified herbal formula's chart according to the addition and reduction of compositional herbs in Dong-uibogam(東醫寶鑑) and Bangjehak(方劑學)

• 대한본초학회지
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• 제24권4호
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• pp.101-106
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• 2009

Objectives : We investigated the anti-aging effects on skin with 9 Repetitive steaming and fermenting herbal composition extract (FHE). Methods : Herbal composition is comprised of Panax Ginseng, Rehmannia glutinosa, Polygonum multiflorum and Polygonatum Sibiricum. They steamed and fermented with Saccharomyces cerevisiae and Lactobacillus brevis by turns at 9 times. We measured various effects related to skin aging such as scavenging activity against free radical, cell proliferation, collagen synthesis and toxicity of 9 repetitive steaming and fermenting herbal composition extract were evaluated and compared with herbal composition extract (HE). Results : As the number of steaming and fermenting cycle increased free-radical scavenging activity were increased. But cell proliferating ratio was not increased when the number of steaming and fermenting cycle. The FHE could significantly increase the collagen synthetic ratio compared with HE treated group. And, FHE was showed no toxicity at all tested concentrations. Conclusions : The results of our study propose that FHE has good anti-aging effects on skin.

• 대한한의학방제학회지
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• 제32권3호
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• pp.277-296
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• 2024

Objective : Dyspepsia is one of the most common ailments among Koreans, leading to a continuously expanding market for liquid digestive solutions. These products are popular due to their convenience and low risk of side effects. However, there is a lack of research on the basic prescription composition of these ingredients and their precise indications according to Korean Medicine. Methods : Drugs were selected from the Korea Pharmaceutical Information Service website (http://www.health.kr), focusing on oral and liquid products classified under the Ministry of Food and Drug Safety's category of stomach and digestive aids (category 233). Frequency analysis was conducted to determine the occurrence and combinations of herbal ingredients within each product. Additionally, the four properties and five flavors of each product were calculated using their herbal ingredient composition ratios, and Pearson correlation coefficients were employed to verify the linear relationships between the composition ratios of the ingredients. Results : A comparative analysis of 33 liquid digestive medicines revealed that Zingiberis Rhizoma was the most frequently used herb. The most common dual-herb combination was Zingiberis Rhizoma and Citri Unshius Pericarpium, and the most prevalent tri-herb combination was Zingiberis Rhizoma, Citri Unshius Pericarpium, and Cinnamomi Cortex. Pearson correlation coefficient analysis showed a strong positive correlation between the composition ratios of Zingiberis Rhizoma and Cinnamomi Cortex. The analysis of four properties and five flavors indicated that products with warm and bitter flavors were the most common. Conclusions : The most frequently used herbal combination in liquid digestive solutions was Zingiberis Rhizoma, Citri Unshius Pericarpium, and Cinnamomi Cortex. This composition is suitable for treating dyspepsia caused by cold-dampness in the digestive system.

• 대한한의학방제학회지
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• 제22권2호
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• pp.45-54
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• 2014

Objectives : The main objective of this study is to classify herbal components to 4 groups which are similar to Gunsinjwasa grades by using herbal composition ratio of prescription. Another objective is to design the searching system which compares prescriptions and improves efficiency with 4 groups like Gunsinjwasa grades. Methods : This study was proceeded with Acess 2007 on Microsoft Windows 7 and we created composition ratio based on weight by using prescriptions of Donguibogam, Uihagipmun and Banghakhabpyun. We could make comparison and searching method of prescriptions. Results : We could search using composition ratio degree of herbs which composes prescription. And the similarity comparison of prescription was possible with value from 0 to 10. Conclusions : We could increase the accuracy of the searching prescriptions and comparison with putting into the information about composition degree and composition ratio of herbs which compose a prescription.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2020년도 춘계학술대회
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• pp.9-9
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• 2020

Many modern people are exposed to chronic inflammatory diseases, such as inflammatory bowel disease (IBD), atopic dermatitis and immune disorder. Among those chronic diseases, the incidence ratio of IBD has been increased. IBD, including Crohn's disease and ulcerative colitis (UC), is known to cause abnormal inflammation in intestinal tissue. UC is accompanied by abdominal pain, bloody stool and diarrhea. Many therapeutic agents, such as sulfasalazine, corticosteroids, immunosuppressive agents, have been used for treating UC. However, those agents have side-effects and temporary effects on UC. The aim of this study was to investigate the effect of herbal medicine on UC and relationship between UC and intestinal bacteria according characteristic of herbal medicine. To determine the effect of herbal medicine on UC, various herbal medicine were chosen within oriental medicine category such as cheongyeol and onyeol medicine. In this study, we found carthami fructus, included in cheongyeol medicine, had stronger effect than onyeol medicine. Also, we determined influence of carthami fructus against lactic acid bacteria. Catthami fructus and lingon berry extracts affected the composition of mice intestinal bacteria in mice fecal. The symptoms of UC could be regulate by using herbal medicine, according to characteristic of herbal medicine. Also, herbal medicine might be change body condition to healthy by controlling intestinal bacteria composition. Herbal medicine characteristic could be a therapeutic agent by revealing relationship between intestinal bacteria and UC.

• 대한본초학회지
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• 제24권1호
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• pp.121-131
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• 2009

Objectives：This study was designed to investigate the effects of herbal composition and fermented Cervi Pantotrichum Cornu on the growth of longitudinal bone in the adolescent male rats. Methods： Longitudinal bone growth was measured by fluorescence microscopy. To examine the effects on the growth plate metabolism, the total height of growth plate and the induction of local insulin-like growth factor-1 (IGF-1) and bone morphogenetic protein-2 (BMP-2) were measured. Results： The herbal composition treatment enhanced longitudinal bone growth and total heght of growth plate and promoted the induction of local IGF-1 and BMP-2 of growth plate. Conclusions： This study showed that the herbal composition have the effect of bone growth in adolescent rats and might be used for the growth delayed adolescent and inherent growth failure patient.

• 사상체질의학회지
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• 제24권3호
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• pp.80-92
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• 2012

Objectives The purpose of this study is to investigate the effects of korean herbal bathing extracts composition 1 and composition 2 on Th2 cytokine production in MC/9 mast cells. Methods The effects of composition 1, 2 was analyzed by ELISA and Real-time PCR in MC/9 mast cells. Levels of IL-5, IL-13 were measured using enzyme-linked immunosorbent assays(ELISA). mRNA levels of IL-4, IL-5, IL-6, IL-13 were analyzed with Real-time PCR. Results Composition 1, 2 inhibited the IL-5, IL-13 production significantly(p<.001) in comparison to PI-control group at concentration of 100 ${\mu}g/mL$, 200 ${\mu}g/mL$. Composition 1, 2 inhibited the IL-4, IL-5, IL-13 mRNA expression significantly in comparison to PI-control group at concentration of 100 ${\mu}g/mL$, 200 ${\mu}g/mL$. Composition 1 inhibited the IL-6 mRNA expression significantly in comparison to PI-control group at concentration of 200 ${\mu}g/ml$. Composition 2 inhibited the IL-6 mRNA expression significantly in comparison to PI-control group at concentration of 100 ${\mu}g/mL$, 200 ${\mu}g/mL$. Conclusions These results indicate that composition 1, 2 has the effect of decreasing the Th2 cytokine production in the MC/9 mast cell.

• 한방비만학회지
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• 제22권1호
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• pp.86-92
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• 2022

26명의 환자에게 8~12주동안 산삼복합약침과 한약을 병행한 식이요법을 시행하여 체성분 변화에 미치는 영향을 알아보았다. 체성분 검사 결과 체중, BMI, 골격근량, 체지방량, 복부지방률, 내장지방단면적, 체지방률이 유의하게 감소하였고, 체중이 감소하면서 골격근량이 감소하긴 하였으나 체지방량 위주의 감소로 골격근의 비율은 오히려 유의하게 증가하였다. 태음조위탕을 증례에 맞게 가감하고, 하루 한 시간 혹은 만 보 걷기의 운동지도를 통해 하루 400~800 kal의 초저열량 식이로 인해 야기될 수 있는 부작용 중 일시적인 현기증과 무기력감 외에 탈모, 부종, 설사, 월경 이상 등은 관찰되지 않았다. 향후 체성분 변화뿐만 아니라 생화학적 검사나 골밀도 검사를 통한 장기적인 탐색이 필요할 것으로 생각한다.

• 대한한의학방제학회지
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• 제15권1호
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• pp.107-115
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• 2007

Objectives : The aim of this study is to analyze the prescription used for dysuria in herbal medication. Methods : Investigating the Oriental Medicine textbooks, I found the prescription used for dysuria. So I analyzed the herbal medication for frequency or compositon and classified it. Results : 1. The most used prescription on dysuria is Paljung-san. 2. The order of frequency of herb for treating dysuria is Moktong, Hwalseok, Gamcho, 3. The group of Yisusamseopyak is used for main prescription about 42%.