Herbal Formula Science (대한한의학방제학회지)

The Korean Medicine Society for the Herbal Formula Study (대한한의학방제학회)
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Prescriptive analysis of liquid gastric digestive solutions

액상형 건위소화제의 방제학적 분석

  • Hong Seok Lee (College of Korean Medicine, Daegu Haany University) ;
  • Min Ju Kim (College of Korean Medicine, Daegu Haany University) ;
  • Ye Bin Shin (College of Korean Medicine, Daegu Haany University) ;
  • Soo Myeong Kim (College of Korean Medicine, Daegu Haany University) ;
  • Sung Jong Shin (College of Korean Medicine, Daegu Haany University) ;
  • Kyung Hwan Jegal (College of Korean Medicine, Daegu Haany University)
  • 이홍석 (대구한의대학교 한의과대학) ;
  • 김민주 (대구한의대학교 한의과대학) ;
  • 신예빈 (대구한의대학교 한의과대학) ;
  • 김수명 (대구한의대학교 한의과대학) ;
  • 신성종 (대구한의대학교 한의과대학) ;
  • 제갈경환 (대구한의대학교 한의과대학)
  • Received : 2024.08.01
  • Accepted : 2024.08.22
  • Published : 2024.08.31
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Abstract

Objective : Dyspepsia is one of the most common ailments among Koreans, leading to a continuously expanding market for liquid digestive solutions. These products are popular due to their convenience and low risk of side effects. However, there is a lack of research on the basic prescription composition of these ingredients and their precise indications according to Korean Medicine. Methods : Drugs were selected from the Korea Pharmaceutical Information Service website (http://www.health.kr), focusing on oral and liquid products classified under the Ministry of Food and Drug Safety's category of stomach and digestive aids (category 233). Frequency analysis was conducted to determine the occurrence and combinations of herbal ingredients within each product. Additionally, the four properties and five flavors of each product were calculated using their herbal ingredient composition ratios, and Pearson correlation coefficients were employed to verify the linear relationships between the composition ratios of the ingredients. Results : A comparative analysis of 33 liquid digestive medicines revealed that Zingiberis Rhizoma was the most frequently used herb. The most common dual-herb combination was Zingiberis Rhizoma and Citri Unshius Pericarpium, and the most prevalent tri-herb combination was Zingiberis Rhizoma, Citri Unshius Pericarpium, and Cinnamomi Cortex. Pearson correlation coefficient analysis showed a strong positive correlation between the composition ratios of Zingiberis Rhizoma and Cinnamomi Cortex. The analysis of four properties and five flavors indicated that products with warm and bitter flavors were the most common. Conclusions : The most frequently used herbal combination in liquid digestive solutions was Zingiberis Rhizoma, Citri Unshius Pericarpium, and Cinnamomi Cortex. This composition is suitable for treating dyspepsia caused by cold-dampness in the digestive system.

Keywords

Acknowledgement

This research was supported by a grant from Daegu Haany University Ky·lin Foundation in 2023.

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